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Using nominal group technique to compare patients' and clinicians' perspectives on symptoms in multiple myeloma to inform the development of a self management tool for patients with relapsed myeloma.

BackgroundThe nominal group technique (NGT) allows stakeholders to directly generate items for needs assessment. The objective was to demonstrate the use of NGT to inform the development of a healthcare app in patients with relapsed myeloma. Healthcare professionals with experience in the care of patients with relapsed/refractory myeloma were invited to participate.MethodsOne NGT group was conducted. In the group, health care professionals working in haematology were asked to vote anonymously in order of highest priority, on symptoms previously highlighted by relapsed/refractory myeloma patien

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… Participant (Myeloma patients) Number: 15 Age 18–45 years | 0 46–55 years | 1 56–65 years | 8 66–80 years | 6 80 + years | 0 Gender Male | 9 Female | 6 Length of Diagnosis < 2 years | 0 2–5 years | 7 5–10 years | 2 >10 years | 5 Unknown | 1 Marital Status: Single (never married) | 1 Married | 11 Separated/Divorced …

A Qualitative Study of the Initial Diagnosis and Treatment Experience of Black Patients with Newly Diagnosed Acute Myeloid Leukemia.

PURPOSE: Black patients with acute myeloid leukemia (AML) experience disparate outcomes, and factors such as structural racism and differential treatment access have been implicated. We sought to understand the experience of Black patients with newly diagnosed AML to gain insight into their unique experience. METHODS: We interviewed Black patients ≥18 years of age with newly diagnosed AML (diagnosed from 7/1/2021 to 7/31/2022) over Zoom. Interviews were conducted by the same interviewer, with concordance in race between the interviewer and interviewees. A rapid qualitative content analysis wa

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… 6 (60) Female | 4 (40) Primary vs. secondary AML, N (%) | Primary | 3 (30) Secondary | 7 (70) Current/recent treatment, N (%) | Hypomethylating agents | 6 (60) Allogeneic hematopoietic stem cell transplant | 3 (30) Clinical trial | 1 (10) Marital status, N (%) | Single | 2 (20) Married | 6 (60) Divorced …

Survival prognosis evaluation in advanced breast cancer patients: a study on the application of the advanced lung cancer inflammation index.

BackgroundInflammation and nutritional status play critical roles in tumor initiation and progression. Advanced Lung Cancer Inflammation Index (ALI) has gained widespread attention as a novel biomarker for cancer prognosis evaluation.MethodsThis retrospective study analyzed 163 advanced breast cancer patients with distant metastasis (Guangxi Medical University Cancer Hospital, 2016-2023). Patients were stratified into high-ALI (n=64) and low-ALI (n=99) groups via K-means clustering. Kaplan-Meier survival curves with log-rank testing were used to assess survival differences, while Cox proportio

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… 0.6734 No | 81 (81.8%) | 54 (84.4%) | Yes | 18 (18.2%) | 10 (15.6%) | Diabetes, n(%) | | | 0.2655 No | 96 (97.0%) | 59 (92.2%) | Yes | 3 (3.0%) | 5 (7.8%) | Marital status, n(%) | | | 0.9515 Married | 91 (91.9%) | 58 (90.6%) | Unmarried | 4 (4.0%) | 2 (3.1%) | Widow | 3 (3.0%) | 3 (4.7%) | Divorced …

Программа оказания помощи пациентам, страдающим множественным склерозом, позволяет повысить уровень знаний и расширить права и возможности людей: предварительное, послеиспытательное многоцентральное исследование.

ЦЕЛЬ: Множественный склероз (МС) связан со сложными потребностями и потребностями, которые требуют ухода с учетом интересов пациентов. Программы для пациентов-экспертов (ЭО) способствуют передаче знаний посредством взаимного обучения, способствуя расширению возможностей пациентов в плане самостоятельного лечения своих заболеваний. На основе предыдущего исследования целевой группы мы разработали программу ЕР для НР, координируемую профессионалами-медиками, для осуществления в различных справочных единицах НР Каталонии (Южная Западная Европа). Цель этого исследования состояла в том, чтобы органи

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… Relapsing MS n  = 57 Progressive MS n  = 55 p -value Sociodemographic characteristics Sex, n (%) Female 46 (80.7) 31 (56.4) 0.0055 a Male 11 (19.3) 24 (43.6) Age (years), median (IQR) 44.0 (38.0, 50.0) 50.0 (46.0, 58.0) 0.0001 b Marital status, n (%) Single, separated, divorced, widow(er) 12 (21.8 …

Cancer burden across the South Asian Association for Regional Cooperation in 2022.

ObjectiveThe objective of this study is to present a cross-sectional analysis of cancer burden in the South Asian Association for Regional Cooperation (SAARC) region and explain unique characteristics of its cancer burden as compared with the rest of the world.Methods and analysisUsing publicly available data from the Global Cancer Observatory (GCO) and the World Bank, we collected cancer statistics and population statistics for Afghanistan, Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka from 2017 to 2022.ResultsThe number of newly diagnosed cases in the region was 1 8

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… Sun, sand & separation: Maldives has world’s highest divorce rat . WION News ; 2016 . 23 Basu P , Hassan S , Fileeshia F , et al . Knowledge, attitude and practices of women in Maldives related to the risk factors, prevention and early detection of cervical cancer . …

Nomogram model for predicting frailty of patients with hematologic malignancies - A cross-sectional survey.

ObjectiveThis study aimed to develop and validate an assessment tool for predicting and mitigating the risk of frailty in patients diagnosed with hematologic malignancies.MethodsA total of 342 patients with hematologic malignancies participated in this study, providing data on various demographics, disease-related information, daily activities, nutritional status, psychological well-being, frailty assessments, and laboratory indicators. The participants were randomly divided into training and validation groups at a 7:3 ratio. We employed Lasso regression analysis and cross-validation technique

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… 65 (27.2) | 24 (23.3) College | 89 (26.0) | 43 (33.3) | 46 (21.6) | 64 (26.8) | 25 (24.3) a Marital status Unmarried/Single | 57 (16.7) | 20 (15.5) | 37 (17.4) | χ 2 = 0.364 | 0.833 | 42 (17.6) | 15 (14.6) | χ 2 = 0.515 | 0.773 Married | 270 (78.9) | 104 (80.6) | 166 (77.9) | 187 (78.2) | 83 (80.6) Divorced …

Validation study of the Functional Assessment of Cancer Therapy-Cognitive Function-Version 3 for the Portuguese population.

BackgroundCancer-related cognitive impairment is a common and potentially debilitating symptom experienced by patients with non-central nervous system (CNS) cancers, with negative impact on their quality of life. The Functional Assessment of Cancer Therapy-Cognitive Function-Version 3 (FACT-Cog-v3) is the most extensively used instrument specifically developed to evaluate cognitive complaints in adult cancer patients. Nevertheless, this self-report measure is not yet validated for the Portuguese population. Therefore, the purpose of this study was to evaluate the psychometric properties of the

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… Sociodemographic and clinical characteristics of the sample (N = 281) SD standard deviations Characteristic | N (%) Age (Years) [Mean (SD), range] | 45.97 (9.00), 18–65 Gender | Female | 268 (95.4%) Male | 13 (4.6%) Marital status | Single | 55 (19.6%) Married | 148 (52.7%) Cohabitation | 34 (12.1%) Divorced …

Strategies to improve patient-reported outcome completion rates in longitudinal studies.

PURPOSE: The quality of patient-reported outcome (PRO) data can be compromised by non-response (NR) to scheduled questionnaires, particularly if reasons for NR are related to health problems, which may lead to unintended bias. The aim was to investigate whether electronic reminders and real-time monitoring improve PRO completion rate. METHODS: The population-based study "Quality of life in Danish multiple myeloma patients" is a longitudinal, multicentre study with consecutive inclusion of treatment-demanding newly diagnosed or relapsed patients with multiple myeloma. Education of study nurses

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… Table 1 Demographic and disease characteristics at entry P number of patients, SD standard deviation, IQR interquartile range, IMWG International Myeloma Working Group, HDT high dose therapy with stem cell support, ISS International Staging System a Separated, divorced, widow or unmarried b Missings …

Understanding what matters most to people with multiple myeloma: a qualitative study of views on quality of life.

BACKGROUND: Multiple myeloma is an incurable haematological cancer that affects physical, psychological and social domains of quality of life (QOL). Treatment decisions are increasingly guided by QOL issues, creating a need to monitor QOL within clinical practice. The development of myeloma-specific QOL questionnaires has been limited by a paucity of research to fully characterise QOL in this group. Aims of the present study are to (1) explore the issues important to QOL from the perspective of people with multiple myeloma, and (2) explore the views of patients and clinical staff on existing Q

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… groups (n = 11) Gender | | | | Male | 10 | 12 | 8 | 30 Female | 10 | 8 | 3 | 21 Age | | | | Median (range) | 66 (41–78) | 63.5 (46–81) | 60 (41–70) | 64 (41–81) <65 | 10 | 12 | 6 | 27 ≥65 | 10 | 8 | 5 | 24 Marital status | | | | Single | 0 | 2 | 1 | 3 Married/partnered | 14 | 15 | 9 | 38 Divorced …

A chain mediation model reveals the association between metacognition and quality of life in hematologic tumor patients.

The study aims to explore the relationship among metacognition (MC), fear of disease of progression (FoP), psychological distress (PD), and quality of life (QoL), and verify whether FoP and PD have a chain mediating effect between MC and QoL. 231 hematologic tumor patients in a large tertiary hospital were investigated by using Meta-Cognitions Questionnaire-30, Fear of Progression Questionnaire-Short Form, Hospital Anxiety and Depression Scale, and Functional Assessment of Cancer Therapy scale. Data analyses were performed using IBM SPSS (version 25.0) and the PROCESS macro (version 4.1). The

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… Variables Group N % Age (year) < 60 201 87.0 ≥ 60 30 13.0 Sex Male 127 55.0 Female 104 45.0 Marital status Married 190 82.3 Unmarried/Divorced/Widowed 8 (3.4) 17.7 Education level High school/Technical secondary school and below 177 76.6 College degree or above 54 23.4 Working status Employed 21 (9.1 … Variables | Group | N | % Age (year) | < 60 | 201 | 87.0 ≥ 60 | 30 | 13.0 Sex | Male | 127 | 55.0 Female | 104 | 45.0 Marital status | Married | 190 | 82.3 Unmarried/Divorced/Widowed | 8 (3.4) | 17.7 Education level | High school/Technical secondary school and below | 177 | 76.6 College degree or above …

Use of Herbal Medicine Is Associated With Late-Stage Presentation in Tanzanian Patients With Cancer: A Survey to Assess the Utilization of and Reasons for the Use of Herbal Medicine.

PurposeIn Tanzania, patients with cancer present late with advanced stages. Among other reasons, the use of herbal medicine (HM) might contribute to delay in diagnosis and treatment. This study aims to understand the utilization of HM and the reasons for its' use.MethodsA semistructured 30-item questionnaire with closed- and open-ended questions was applied to a cohort of patients with cancer at Kilimanjaro Christian Medical Centre. Content analysis was performed for answers to open-ended questions.ResultsThree hundred two patients were interviewed, 50.9% males and 49.1% females. The mean age

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… Two hundred four participants were married (67.6%), 49 were widowers (16.2%), 33 were single (10.9%), and 16 (5.3%) were divorced. …

Sitz bath with different concentrations of diluted povidone-iodine for prevention of perianal infection in patients with hematological malignancies undergoing chemotherapy: a randomized controlled trial in a tertiary hospital in China.

BackgroundThe incidence of perianal infection in patients with hematologic malignancies undergoing chemotherapy can reach 40-50%. Despite advances in medical technology and improved management strategies, the rate of perianal infection following chemotherapy remains substantial. Currently medicated sitz baths are not widely adopted in clinical practice due to their side effects and limited applicability. Povidone-iodine (PI) is a commonly used clinical broad-spectrum antiseptic, yet its efficacy in preventing perianal infection has not been adequately studied. Therefore, we aimed to evaluate t

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… . (%) Married | 42 (70.0) | 30 (55.6) | 35 (61.4) | 5.339 a | 0.385 Unmarried | 16 (26.7) | 19 (35.2) | 16 (28.1) | | Divorce | 2 (3.33) | 5 (9.26) | 6 (10.5) | | Primary caregiver, no. (%) Spouse | 30 (50.0) | 17 (31.5) | 33 (57.9) | 9.843 a | 0.043 Parents | 16 (26.7) | 24 (44.4) | 17 (29.8) | …

beta Testing a Medical Symptom Management для людей с продвинутым раком: Исследование одноразовой осуществимости и приемлемости.

КОЛИЧЕСТВО: Люди, страдающие раком, имеют более частые и серьезные симптомы, чем лица, страдающие ранней стадией заболевания. Обычные, тревожные симптомы включают трудности со сном, беспокойство и неуверенность, усталость и депрессию. Когнитивная поведенческая терапия (КБТ) и терапия принятия и принятия обязательств (АКТ) эффективно устраняют эти симптомы, но зачастую они являются слишком продолжительными для пациентов с несколькими назначениями, ограниченной энергией и конкурирующими приоритетами. Кратко говоря, мобильные медицинские услуги (медицинское обслуживание) являются доступной альтер

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… | Values Sex, n (%) Female | 6 (54.5) Male | 5 (45.5) Race, n (%) Black | 2 (18.2) Middle Eastern | 1 (9.1) White | 8 (72.7) Age (y), mean (SD) | 65.91 (13) Time since diagnosis (y), mean (SD) | 10.55 (8) Education (y), mean (SD) | 15.64 (2) Marital status, n (%) Married | 8 (72.7) Divorced | 2 (18.2 …

Exploring Barriers and Facilitators to Engagement of an Online Acceptance and Commitment Therapy Intervention for Cancer Survivors With Chronic Painful Chemotherapy-Induced Peripheral Neuropathy: Qualitative Interview Study.

BackgroundOnline self-management interventions for cancer survivors are increasingly being used, but engagement is often difficult for patients. Given the importance of engagement for intervention effectiveness, identifying patient-reported barriers and facilitators is essential.ObjectiveThe aim of this study was to qualitatively examine barriers and facilitators influencing engagement with an online self-management intervention, offered with or without guidance, for cancer survivors experiencing chronic painful chemotherapy-induced peripheral neuropathy (CIPN).MethodsPatients who took part in

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… I am a mother with adult children who is divorced and who lives alone. I can’t do anything with examples related to partners . [P2] In addition, some patients indicated that they were already familiar with the content: Well I have found that I do a lot of things already. …

Living and dying with incurable cancer: a qualitative study on older patients' life values and healthcare professionals' responsivity.

BackgroundIn ageing Western societies, many older persons live with and die from cancer. Despite that present-day healthcare aims to be patient-centered, scientific literature has little knowledge to offer about how cancer and its treatment impact older persons' various outlooks on life and underlying life values. Therefore, the aims of this paper are to: 1) describe outlooks on life and life values of older people (≥ 70) living with incurable cancer; 2) elicit how healthcare professionals react and respond to these.MethodsSemi-structured qualitative interviews with 12 older persons with advan

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… .” - i11 (male, 83, divorced, lost contact with his children) Main theme 2: Being supported by others Sub-themes | Related life values | Representative quotes 2.1 “Being there” | Receiving love from one’s fellow human beings: family, friends, religious communities (charity, support) | Q12a: “ What does …

The Psychological Inflexibility in Pain Scale (PIPS) in Brazilian patients with chronic cancer pain: translation, cross-cultural adaptation, and validation study.

BackgroundThe Psychological Inflexibility in Pain Scale (PIPS) was developed to measure avoidance and cognitive fusion.ObjectivesTo translate, cross-culturally adapt, and analyze the measurement properties of the Psychological Inflexibility in Pain Scale (PIPS) in Brazilian patients with chronic cancer pain.MethodsQuestionnaire translation, cross-cultural adaptation, and validation studies were conducted in two hospitals in northeastern Brazil. The measurement properties tested included structural validity, construct validity, reliability, and internal consistency. The following assessment ins

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… Table 1 Personal and social characteristics of the patients included in the study (n = 122) Variables | Number (%) Sex | Male | 42 (34.4%) | Female | 80 (65.6%) Marital status | Married | 62 (50.8%) | Divorced | 7 (5.7%) | Single | 50 (41%) | Widowed | 3 (2.5%) Scholarity | Primary education | …

Доклад по делу: Существенное сокращение повреждений и структурные нейронные изменения после лечения ибогина при множественном склерозе.

Множественный склероз (MS) — изнуряющее нейродегенеративное заболевание, характеризующееся демиэлированием и нейронной потерей. Традиционная терапия часто не может остановить прогрессирование заболеваний или обратный неврологический дефицит. Ибогаин, психоактивный алкалоид, был предложен в качестве потенциального нейрогенеративного агента в силу его многогранного фармакологического профиля. Мы представляем два тематических исследования пациентов MS, которые прошли новое лечение ибогином, высветив значительные нейроимации и клинические улучшения. Пациент А продемонстрировал существенное сокраще

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… Patient B Also in February 2023, Ambio received a 44-year-old female (“PB”) who was diagnosed with secondary progressive MS (SPMS) in 2018, as well as complex PTSD (CPTSD) from childhood trauma and a recent divorce following 17 years of marriage. …

Optimizing Patient Education of Oncology Medications: A Patient Perspective.

The medication information needs of patients with cancer have been primarily studied using quantitative methods and little qualitative research on this topic exists. The purpose of this study was to explore patients' perspectives of optimal oncology medication education provided to patients at the Nova Scotia Health Authority (NSHA). Adult (≥ 18 years) outpatients in medical, gynecological and hematology oncology at NSHA were invited to participate in focus groups, which were audio-recorded, transcribed and analyzed thematically. Three focus groups, including 21 outpatients, were conducted. Fo

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… Participants’ marital statuses included married, divorced, common-law, single, and widowed. Additional demographic and clinical characteristics are presented in Table 1 . …

Patients' Perceptions of Physician-Patient Discussions and Adverse Events with Cancer Therapy.

OBJECTIVES: Patients with cancer who are treated with chemotherapy report adverse events during their treatment, which can affect their quality of life and increase the likelihood that their treatment will not be completed. In this study, patients' perceptions of the physician-patient relationship and communication about cancer-related issues, particularly adverse events were examined. METHODS: We surveyed 508 patients with cancer concerning the occurrence of adverse events and their relationship and communication with their physicians regarding cancer, treatment, and adverse events. RESULTS:

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… Education High school or less | 240 (47) Some college | 151 (30) College graduate | 117 (23) Annual household income, $ * <35,000 | 143 (28) 35,000–75,000 | 113 (22) >75,000 | 127 (25) Declined to state | 126 (25) Household status Married or living with partner | 359 (71) Single, never married | 29 (6) Divorced …

Навязчивое сексуальное поведение и проблематичное использование порнографии: всеобъемлющий, междисциплинарный и экспертный обзор описательной информации с указанием предлагаемых направлений будущей деятельности.

СПРАВОЧНАЯ ИНФОРМАЦИЯ И МАТЕРИАЛЫ: Характер и классификация дисрегулированного сексуального поведения по-прежнему широко обсуждаются. Сексуальные расстройства, связанные с сексуальным поведением, и проблематичное использование порнографии (PUP) two Наиболее часто изученные конструкции в этой области, каждая из которых имеет значительные последствия для психического здоровья, межличностного функционирования и более широкого благосостояния. Хотя научные результаты по этим темам за последнее десятилетие быстро расширились, в последних обзорах основное внимание, как правило, уделялось конкретным п