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Health assessment of harbour porpoises (PHOCOENA PHOCOENA) from Baltic area of Denmark, Germany, Poland and Latvia.

Harbour porpoise (Phocoena phocoena), the only resident cetacean species of the Baltic Sea is formed of two subpopulations populations, occurring in the western Baltic, Belt Seas and Kattegat and the Baltic Proper, respectively. Harbour porpoises throughout these areas are exposed to a large number of human activities causing direct and indirect effects on individuals, that might also harm this species on a population level. From Latvia, Poland, Germany and Denmark 385 out of 1769 collected dead harbour porpoises were suitable for extensive necropsy. The animals were collected between 1990 and…

Tick-borne encephalitis virus vaccination breakthrough infections in Germany: a retrospective analysis from 2001 to 2018.

OBJECTIVES: There are few data available regarding the clinical course of tick-borne encephalitis virus (TBEV) vaccination breakthrough infections. The published studies suggest that vaccination breakthrough infections may have a more severe course than native TBEV infection in unvaccinated individuals-potentially due to antibody-dependent enhancement. Here we report a large analysis of vaccination breakthrough infections. METHODS: This retrospective analysis was based on a national surveillance dataset spanning the years 2001-2018. Variables reflecting disease severity, such as 'CNS symptoms

Whole genome sequencing suggests transmission of Corynebacterium diphtheriae-caused cutaneous diphtheria in two siblings, Germany, 2018.

In September 2018, a child who had returned from Somalia to Germany presented with cutaneous diphtheria by toxigenic Corynebacterium diphtheriae biovar mitis. The child's sibling had superinfected insect bites harbouring also toxigenic C. diphtheriae. Next generation sequencing (NGS) revealed the same strain in both patients suggesting very recent human-to-human transmission. Epidemiological and NGS data suggest that the two cutaneous diphtheria cases constitute the first outbreak by toxigenic C. diphtheriae in Germany since the 1980s.

Assessing minimal medical statistical literacy using the Quick Risk Test: a prospective observational study in Germany.

OBJECTIVES: To assess minimal medical statistical literacy in medical students and senior educators using the 10-item Quick Risk Test; to assess whether deficits in statistical literacy are stable or can be reduced by training. DESIGN: Prospective observational study on the students, observational study on the university lecturers. SETTING: Charité University Medicine medical curriculum for students and a continuing medical education (CME) course at a German University for senior educators. PARTICIPANTS: 169 students taking part in compulsory final-year curricular training in medical statis

Median urinary iodine concentration reflected sufficient iodine supply in neonates from Northeast Germany in 2005-2006.

PURPOSE: Data from recent adult studies suggest a decline of median urinary iodine concentrations (UIC) in Germany, but since 1996 no German study investigated UIC in neonates. The aim of our study was to investigate UIC and serum thyroid-stimulating hormone (TSH) levels in neonates from Germany. METHODS: We used data from 399 neonates, which were born between April 2005 and November 2006 in the Northeast of Germany. UIC were evaluated by a photometric procedure with Sandell and Kolthoff reaction and afterwards corrected to be comparable with an ICP-MS method. TSH was determined from capillar…

Trends in herpes zoster epidemiology in Germany based on primary care sentinel surveillance data, 2005-2016.

Herpes zoster (HZ) is caused by reactivation of the varicella-zoster-virus (VZV). Childhood varicella vaccination, as recommended in Germany in 2004, may reduce the risk of HZ in vaccinated children but also virus circulation and thus the booster possibility of latent infected persons. In this context we analyzed age-specific trends in HZ epidemiology in Germany using data on HZ-associated outpatient consultations in participating sentinel sites and HZ-associated cases in all hospitals since 2005. We analyzed two separate time periods that differed in sentinel management and data integrity. Fo…

Cryptosporidium spp. and Enterocytozoon bieneusi in introduced raccoons (Procyon lotor)-first evidence from Poland and Germany.

The raccoon (Procyon lotor) carnivore native to North America is a fast spreading, invasive species in the Europe now. At the moment, the hi … osporidium spp. and microsporidia in the introduced raccoons obtained from localities in Poland and Germany. A PCR-based approach that permitted genetic characterization via sequence analysis was applied to raccoon fecal samples (n = 49), collected during 2012-2014. All fecal samples were simultaneously tested with the use of genetic markers, and DNA of m …

First detection of Borrelia burgdorferi-antibodies in free-living birds of prey from Eastern Westphalia, Germany.

Borrelia (B.) burgdorferi sensu lato, the causative agent of Lyme disease, is the most important arthropod-borne zoonosis-pathogen in the No … llected from free-living birds of prey (n = 29) at the rehabilitation centre in Eastern Westphalia, Germany, highlights that birds of prey are also susceptible to B. burgdorferi and react immunologically to an infection. Increased antibody-levels could be found by using a modified Indirect Immunofluorescent-testing in two common buzzards, Buteo buteo, and …

Факторы, влияющие на характер паразитизма тика на лесных грызунах в районах риска энцефалита, переносимых клещами, Германия.

Для понимания систем инфекционных заболеваний существенно важное значение имеет выявление факторов, влияющих на нагрузку отдельных переносчиков. На основе данных программы мониторинга грызунов, проведенной в девяти различных лесных пятнах в южной части Гессен, Германия, мы разработали модели, которые предсказывают тикание (Ixodes spp. и Dermconentor spp.) нагрузки на два вида грызунов Apodemus flavicollis и Myodes glareolus. Модели двух видов грызунов в целом аналогичны, но различаются по некоторым аспектам. Характеристики иксодов spp. нагрузки были подвержены воздействию внешних факторов, так

Совпадение в аннотации оригинала
Identifying factors affecting individual vector burdens is essential for understanding infectious disease systems. Drawing upon data of a rodent monitoring programme conducted in nine different forest patches in southern Hesse, Germany, we developed models which predict tick (Ixodes spp. and Dermacentor spp.) burdens on two rodent species Apodemus flavicolli…

Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) in fulminant blastomycosis in Germany.

In fulminant blastomycosis with multiorgan failure, the earliest diagnosis possible is crucial for successful treatment. If severe acute respiratory distress syndrome (ARDS) develops, miniaturised veno-venous extracorporeal membrane oxygenation (ECMO) might provide a unique and efficacious possibility to prolong the time frame for diagnosis and the beginning of treatment. This is the first report on a case of fatal blastomycosis in Germany. It reminds us to add exotic infections to the differential diagnosis in patients with refractory pneumonia in the era of worldwide tourism.

Impact of biogenic terpene emissions from Brassica napus on tropospheric ozone over Saxony (Germany): numerical investigation.

INTRODUCTION: The role of biogenic emissions in tropospheric ozone production is currently under discussion and major aspects are not well understood yet. This study aims towards the estimation of the influence of biogenic emissions on tropospheric ozone concentrations over Saxony in general and of biogenic emissions from brassica napus in special. MODELLING TOOLS: The studies are performed by utilizing a coupled numerical modelling system consisting of the meteorological model METRAS and the chemistry transport model MUSCAT. For the chemical part, the Euro-RADM algorithm is used. EMISSIONS: A

Changing mortality patterns in East and West Germany and Poland. I: long term trends (1960-1997).

OBJECTIVES: To examine the long term evolution of mortality in the former German Democratic Republic (GDR) in the period from 1960 and its s … expectancy over time by cause of death were examined using data for 1974 and 1989 for both parts of Germany and for 1974 and 1988 for Poland. RESULTS: Male life expectancy in the two parts of Germany diverged twice, in the mid-1960s, favouring the GDR, and in the mid-1970s, giving increasing advantage to the FRG, while female life expectancy remained sim …

Accuracy of death certificates: a population-based, complete-coverage, one-year autopsy study in East Germany.

The Goerlitz Autopsy Study is a population-based autopsy study, conducted in 1987 in the municipality of Goerlitz, population 78,484, in former East Germany. It is unique in that 1,023 (96.5 percent) of the 1,060 subjects who died in the municipality over a period of one year were investigated by full autopsy. An underlying cause was assigned to every death, using the procedures recommended by the International Classification of Diseases, Injuries and Causes of Death, ninth revision, German edition. Assignment of cause of death was done independently by the attending clinician and the patholog…

Workload demands, surgical education and training among resident surgeons in Germany: a cross-sectional questionnaire-based study.

BACKGROUND: The medical system is experiencing increasing systemic workload pressures and a developing shortage of doctors, making the well- … om resident surgeons across multiple surgical specialties, predominantly at university hospitals in Germany. It was designed to assess the quality of resident surgeons' training experiences and gauge their perceptions of their career progression and workload distribution. Furthermore, the questionnaire assessed emotional well-being, workload demands, trai …

Trends in glaucoma diagnosis and medical management in Germany: A nationwide claims data analysis over 10 years.

PURPOSE: Analysing longitudinal trends in recorded diagnosis and medical management of glaucoma in Germany over a 10-year period. METHODS: A retrospective cohort study using nationwide outpatient claims and prescription data from the German statutory health insurance system. Patients with documented glaucoma or glaucoma suspect (ICD-10 H40.*) between 2014 and 2023 were included. Analyses assessed annual diagnosed glaucoma patients, demographic characteristics, proportions of medically treated patients and prescribing patterns of glaucoma medications. Trends in medication classes and number of…

Current skin of color representation in medical school dermatology education in Germany, Austria and Switzerland (DACH region).

BACKGROUND AND OBJECTIVES: Dermatologic diagnosis relies heavily on visual recognition, yet educational resources predominantly depict lighter skin types. While underrepresentation of Skin of Color (SoC) in medical education has been demonstrated in North America, data from German-speaking countries remain lacking. This study assesses the SoC representation in dermatology curricula in the DACH region (Germany, Austria, Switzerland). METHODS: We conducted a questionnaire-based study targeting dermatology departments at all medical schools in the DACH region (n = 57). RESULTS: The response rat…

Cost-effectiveness analysis of pneumococcal conjugate vaccines, PCV21 vs PCV20, in adults aged  ≥60 years in Germany.

BACKGROUND: Higher-valency pneumococcal conjugate vaccines (PCVs) may reduce the burden of adult pneumococcal disease (PD), yet it is unclea … 1 may provide greater health and economic benefits than PCV20 for adult pneumococcal vaccination in Germany, remaining cost-saving across a range of model inputs and scenarios.

Clinical management and outcomes of relapsed NSCLC after chemoradiotherapy and durvalumab consolidation: real-world evidence from Germany.

BACKGROUND: Despite recent advances in the treatment of locally advanced non-small cell lung cancer (NSCLC), most patients relapse after definitive chemoradiotherapy followed by durvalumab consolidation. Due to limited evidence on post-relapse management, no standard treatment approach has been established for this patient population. OBJECTIVES: The objective of this study was to evaluate real-world treatment strategies and clinical outcomes in patients with NSCLC who experienced disease recurrence after durvalumab consolidation. DESIGN: This was a multicenter, retrospective cohort study co

Prevalence of peri-implant disease in Germany: results of the 6th German Oral Health Study (DMS • 6).

OBJECTIVE: To report the prevalence of peri-implant disease and factors associated with peri-implant tissue inflammation in a German population-based cohort comprising younger adults (35- to 44-year-olds) and younger seniors (65- to 74-year-olds) among participants in the 6th German Oral Health Study (DMS • 6). METHOD AND MATERIALS: Data were available for 925 and 788 younger adults and younger seniors, of whom 63 (n = 108 implants) and 163 (n = 477 implants) had at least one dental implant. Probing depth (PD) and bleeding on probing (BOP) were recorded at six sites per implant. For each impl

Hospitalization profiles and complications across ICD and CRT-D implantations in Germany: data from the VIDEO study.

BACKGROUND: Implantable cardioverter-defibrillator (ICD) is a cornerstone therapy for the prevention of sudden cardiac death. However, clinical profiles and in-hospital outcomes may differ according to device type-single-chamber ICD, dual-chamber ICD, or cardiac resynchronization therapy defibrillator (CRT-D). This study aimed to compare hospitalization parameters and peri-procedural complications among patients receiving these device types. METHODS: We retrospectively analyzed 2,001 consecutive ICD recipients (single-chamber: 815; dual-chamber: 463; CRT-D: 723). Baseline characteristics, int