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Blood Pressure Management After Endovascular Therapy for Acute Ischemic Stroke: The BEST-II Randomized Clinical Trial.

IMPORTANCE: The effects of moderate systolic blood pressure (SBP) lowering after successful recanalization with endovascular therapy for acu … f the follow-up infarct volume for each mm Hg decrease in the SBP target, adjusted for the baseline Alberta Stroke Program Early CT score, was -0.29 (95% CI, -0.81 to ∞; futility P = .99). The slope of the utility-weighted mRS score for each mm Hg decrease in the SBP target after endovascular therapy, adjusted for baseline utility-weighted mRS score, was …

Updates in Kidney Transplantation From the 2022 Banff-Canadian Society of Transplantation Joint Meeting: Conference Report.

PURPOSE OF THE CONFERENCE: The 2022 Banff-Canadian Society of Transplantation Meeting in Banff, Alberta, brought together transplant professionals to review new developments across various aspects of solid organ transplantation (SOT) in Canada. SOURCES OF INFORMATION: Presentations included consensus recommendations from expert-led forums; experiences with new procedures and legislation; reports from public health data repositories; original clinical and laboratory research; and industry updates regarding novel technologies. Speakers referenced articles and reports published in peer-reviewed …

How Are Albertans "Adjusting to and Coping With" Dialysis? A Cross-Sectional Survey.

BACKGROUND: Depression and anxiety are commonly reported (40% and 11%-52%) among adults receiving dialysis, compared with ~10% among all Canadians. Mental health in dialysis care is underrecognized and undertreated. OBJECTIVE: (1) To describe preferences for mental health support reported by Albertans receiving dialysis; (2) to compare depression, anxiety, and quality-of-life (QOL) domains for people who would or would not engage in support for mental health; and (3) to explore sociodemographic, mental health, and QOL domains that explain whether people would or would not engage in support fo…

Final 2 year results of the vascular imaging of acute stroke for identifying predictors of clinical outcome and recurrent ischemic eveNts (VISION) study.

UNLABELLED: Among patients with ischemic stroke, little attention has been paid to differentiation between stroke progression and recurrence. We assessed the role of MR imaging in predicting stroke progression, recurrent stroke, and death within 2 years of symptom onset. METHODS: Ischemic stroke or TIA patients were prospectively enrolled. They were examined within 12 hours and had a stroke MR completed within 24 hours of symptom onset. Patients were closely followed neurologically and examined if there was any deterioration in neurological status. Relationships between baseline clinical and

Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data.

BACKGROUND: Evidence regarding whether imaging can be used effectively to select patients for endovascular thrombectomy (EVT) is scarce. We … ormation other than stroke side, categorised baseline imaging features of ischaemic change with the Alberta Stroke Program Early CT Score (ASPECTS) or according to involvement of more than 33% of middle cerebral artery territory, and by thrombus volume, hyperdensity, and collateral status. The primary endpoint was neurological functional disability scored …

Pancreatic islet transplantation in type 1 diabetes: 20-year experience from a single-centre cohort in Canada.

BACKGROUND: Islet transplantation offers an effective treatment for selected people with type 1 diabetes and intractable hypoglycaemia. Long-term experience, however, remains limited. We report outcomes from a single-centre cohort up to 20 years after islet transplantation. METHODS: This cohort study included patients older than 18 years with type 1 diabetes undergoing allogeneic islet transplantation between March 11, 1999, and Oct 1, 2019, at the University of Alberta Hospital (Edmonton, AB, Canada). Patients who underwent islet-after-kidney transplantation and islet transplantation alone o…

USPSTF2013 versus PLCOm2012 lung cancer screening eligibility criteria (International Lung Screening Trial): interim analysis of a prospective cohort study.

BACKGROUND: Lung cancer is a major health problem. CT lung screening can reduce lung cancer mortality through early diagnosis by at least 20 … NG: Terry Fox Research Institute, The UBC-VGH Hospital Foundation and the BC Cancer Foundation, the Alberta Cancer Foundation, the Australian National Health and Medical Research Council, Cancer Research UK and a consortium of funders, and the Roy Castle Lung Cancer Foundation for the UK Lung Screen Uptake Trial.

Несоразмерный небольшой форник с модифицированной микроструктурой в педиатрическом множественном склерозе, показываемом с высокой разрешающей жидкостной диффузионной трактографией.

ОКРУЖАЮЩАЯ СРЕДА: У взрослых с множественным склерозом (MS) диффузионно-тензорная съемка (DTI) выявила явные аномалии объема и диффузии форникса, основного выходного участка гиппокампа (WM). ЦЕЛЬ: Определение того, затрагивает ли форник в педиатрическом плане MS (POMS), используя те же протоколы DTI, что и для взрослых MS (AOMS), что предполагает его участие в курсе болезни на раннем этапе. МЕТОДЫ: Для выявления форников в 11 пациентах в возрасте 13-19 лет и 26 контролерах с высоким разрешением была использована инфекционная трактография с использованием флюидов. Показатели объема и диффузии с

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… Contributor Information Carly Weber, Biomedical Engineering, University of Alberta, Edmonton, Canada. Colin Wilbur, Pediatric Neurology, University of Alberta, Edmonton, Canada. Gregg Blevins, Neurology, University of Alberta, Edmonton, Canada. … Christian Beaulieu, Biomedical Engineering, University of Alberta, Edmonton, Canada; Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada. …

Beyond the cis-binary: Radiation therapists' experiences caring for transgender and gender diverse patients.

INTRODUCTION: Transgender and gender diverse (TGD) people are part of a marginalized and medically underserved group that faces unique chall … utilizing voluntary response sampling methods. Interviews were conducted electronically with RTs in Alberta, and the results informed the development of an online survey that was then sent to RTs across all of Canada and contained both multiple-choice and open-response questions. Descriptive statistics were used to display quantitative survey data, and qu …

Practical Guidance for the Expanded Implementation and Provision of Bispecific Antibodies for Diffuse Large B-Cell Lymphoma (DLBCL) Across Canada.

(1) Background: Bispecific antibodies (BsAbs) for the treatment of relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) can be delivered in ambulatory healthcare settings; however, the safe and effective management of potential side effects, such as cytokine release syndrome (CRS), requires protocolized monitoring and management. (2) Methods: An Expert Working Group (EWG) of nine hematologists from across Canada, with experience in leading BsAb program implementation, combined a review of published literature, a comparison of national/provincial/regional guidance documents and protoco

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… AHS Alberta Referral Directory > Malignant Hematology Alberta Health Services Calgary, AB, Canada 2025 54. BCCA Bispecific Antibody Nursing Process BC Cancer Agency Vancouver, BC, Canada 2024 55. … Cancer Care Alberta Clinical Practice Guideline, Lymphoma > Prevention and Management of Toxicities of Bispecific Antibodies in Lymphoma Alberta Health Services Calgary, AB, Canada 2024 115 120 82. …

Symptoms, Symptom Profiles, and Healthcare Utilization in Patients with Hematologic Malignancies: A Retrospective Observational Cohort Study and Latent Class Analysis.

Symptom burden is known to be high in patients with hematologic malignancies and can adversely impact patients' quality of life. The aims of this retrospective observational cohort study were to explore symptoms in patients with hematologic malignancies, including during the last year of life, to explore symptom profiles in patients with hematologic malignancies, and to explore associations among symptoms/symptom profiles and demographic, clinical, and treatment-related variables. Symptom prevalence and severity and symptom profiles were explored in patients with hematologic malignancies who c

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… The first case of COVID-19 in Alberta was announced in early March 2020 with restrictions on gatherings coming into effect on 12 March 2020 [ 137 ]. Cancer Care Alberta rapidly implemented virtual clinic visits for many patients in March 2020 [ 138 ]. … Alberta. …

Proceedings of the Canadian Society of Allergy and Clinical Immunology Annual Scientific Meeting 2018

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… A11 Trends in asthma epidemiology in Alberta from 1995 to 2015 Ana-Maria Bosonea 1 , Heather Sharpe 1 , Harissios Vliagoftis 1 , Larry Svenson 1 , Dean Befus 1 1 Department of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada Correspondence: Ana-Maria Bosonea Allergy, Asthma … , Edmonton, Alberta, Canada Correspondence: Zihang Lu # Zihang Lu and Christopher J. …

A Population-Based Analysis of Quality Indicators in CKD.

BACKGROUND AND OBJECTIVES: Awareness of CKD remains low in comparison with other chronic diseases, such as diabetes, leading to low use of preventive medications and appropriate testing. The objective of this study was to evaluate the quality of care provided to people with and at risk of CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a population-based analysis of all Albertans with eGFR=15-59 ml/min per 1.73 m2 between April 1, 2011 and March 31, 2012 as well as patients with diabetes (as of March 31, 2012). We assessed multiple quality indicators in people with eGFR=15-59…

40th Annual CAPO Conference-Responding to the Human Experience of Cancer and Caring for the Soul: Building on 40 Years of Global Leadership in Psychosocial Oncology.

On behalf of the Canadian Association of Psychosocial Oncology, we are pleased to present the Abstracts from the 2025 Annual Conference, titled "Responding to the Human Experience of Cancer and Caring for the Soul: Building on 40 years of global leadership in psychosocial oncology". The 40th Annual CAPO Conference was held in Toronto from 23 April 2025 to 25 April 2025. In an era marked by the rapid advancement of biologically focused precision medicine, it is imperative to redirect our attention towards the human experience of illness and the soul of medicine. Biomedicine has conceptualized i

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… Background/Rationale or Objectives/Purpose Background: Cancer Care Alberta is a provincial ambulatory program with 17 facilities across Alberta. … Cancer Care Alberta, Calgary. 10.1. …

Резюме, представленные на 32nd Ежегодная конференция Международного общества по изучению качества жизни.

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… The Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital, Nyborg, Denmark, 6 Amsterdam UMC location University of Amsterdam, Medical Library, Research Support, Amsterdam, The Netherlands, 7 University of Calgary, Department of Community Health Sciences, Calgary, Alberta … , 11 University of Sydney, Faculty of Medicine and Health, Sydney Quality of Life Office, Susan Wakil School of Nursing and Midwifery, Sydney, Australia, 12 School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK, 13 Cumming School of Medicine, University of Calgary, Calgary, Alberta …

Feasibility of a tailored and virtually supported home exercise program for people with multiple myeloma using a novel eHealth application.

INTRODUCTION: eHealth exercise interventions have the unique ability to leverage the benefits of in-person programming (tailoring and supervision) with the benefits of home programming (flexibility). There may be a role for eHealth-delivered exercise for people with multiple myeloma (MM), as exercise tailoring and supervision are critical for successful outcomes due to the significant impacts/risks of myeloma-related side effects. The purpose of this study was to determine the safety, feasibility, and preliminary efficacy of a 12-week virtually supported eHealth exercise program. METHODS: Par

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… Funding: The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: GP was supported by the Government of Alberta through the Alberta Graduate Excellence Scholarship, by the Canadian Institutes for Health Research through the Sir … Frederick Banting & Dr Charles Best Canada Graduate Scholarship—Master's, and by the University of Alberta through the Walter H Johns Graduate Fellowship. …

Материалы ежегодной конференции Канадского общества респираторных терапевтов, май 8-10, 2025.

Мы рады представить ряд выдержек из работы ежегодной Конференции по ТРСК. состоявшемся в Оттаве, Онтарио, в мае 8 в адрес 10, 2025, эта конференция включала в себя темы, подготовленные отдельными лицами, имеющими опыт работы в различных областях практики дыхательной терапии. Как видно из следующих резюме, работа наших коллег 2025 :: акцентировали внимание на текущих исследовательских и практических нововведениях, осуществляемых РТ. Мы приложили все усилия для того, чтобы включить все выдержки, принятые Комитетом по программе до предельного срока публикации; вместе с тем просьба иметь в виду, ч

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… We will review our newly chosen ventilator including why it was chosen for Alberta and its functionality for mouthpiece ventilation. … the Continuing Care Health Services Standards that are set by the Alberta government. …

Physical activity programming and counseling preferences among cancer survivors: a systematic review.

BackgroundPhysical activity (PA) participation and adherence among cancer survivors is low, despite research indicating numerous physical, psychological and emotional health benefits of exercise. Tailoring exercise programs specific to the PA preferences in cancer survivors has merit for increasing PA participation and adherence to accrue these benefits. This systematic review identifies and differentiates PA programming and counseling preferences of adult cancer survivors across various cancer survivor groups.MethodsPubMed, SPORTDiscus, Scopus, PsycINFO, EMBASE, Web of Science and CINAHL were

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… , Canada Completed university/college or higher (37.6%) 50.2% No timing; cancer diagnosis Karvinen et al., (2007) [ 74 ] Quantitative -- -- 25.7% -- Married/common law (79.1%) -- -- 20.9% b Alberta, Canada Some post secondary or more (37.8%) 51.0% No timing; cancer diagnosis Karvinen et al., (2011) [ … (74.0%) 24.2% 51 33.0% a Alberta, Canada Some post secondary or more (51%) 34.0% Diagnosed between 2003-2007 Midgley et al., (2017) [ 81 ] Quantitative 66.0 -- 26.0% -- -- -- 43.0 (Median) -- North West England, United Kingdom -- 43.0% Received treatment between 2010 and 2014 Murnane et al., (2012) …

Clinical utility of ustekinumab in Crohn's disease.

The introduction of anti-tumor necrosis factor (TNF) therapy marked an important milestone in the management of moderate-to-severe Crohn's disease (CD). However, there remains a pressing demand for alternative therapeutic options for patients with primary nonresponse, secondary loss of response, or intolerable side effects to conventional treatment and TNF antagonists. Ustekinumab (UST) is a fully human IgG1κ monoclonal antibody that inhibits the p40 subunit shared by the proinflammatory cytokines, the interleukin (IL)-12 and -23. This blockade leads to dampening of the inflammatory cascade an

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… The largest open-label UST experience, including 167 CD patients, was reported by Ma et al from two tertiary care centers in Alberta, Canada. 49 , 50 Using more strict definitions of clinical response (decrease in HBI ≥3 points compared to baseline with complete corticosteroid tapering), 38.9 and 60.3% … Concurrent immunomodulation was identified as a positive predictor of induction response in the GETAID cohort and of maintenance response in both the Alberta and USTEK cohorts. 47 , 50 , 51 This was not replicated in subgroup analysis of the UNITI program, and the potential biological mechanisms are …

Baseline Characteristics of Participants in the Exercise for Cancer to Enhance Living Well (EXCEL) Study: A Canada-Wide Rural-Urban Analysis.

IntroductionExercise interventions improve quality of life and survival for individuals living with and beyond cancer (ILWBC), yet equitable access remains limited. Evidence on characteristics of who enrolls in exercise oncology programs is scarce, leaving gaps for equity-focused recruitment and scale-up, particularly in rural and underserved settings. The EXercise for Cancer to Enhance Living Well (EXCEL) study offers a unique opportunity to examine these issues across a Canada-wide cohort.MethodsEXCEL is an 8-12-week tailored exercise intervention delivered primarily to ILWBC in rural/remote

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… While the majority of sessions were delivered via Zoom, in‐person classes were also available in select rural locations within the Maritime provinces, Alberta, and Ontario [ 14 ]. … Additional program funding provided by the Alberta Cancer Foundation (Grant #N/A). SNCR is a UCalgary Research Excellence Chair and a Killam Laureate. …