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Abstract Proceedings of the 38th Annual Canadian Association of Psychosocial Oncology (CAPO) Conference, June 2023.

On behalf of the Canadian Association of Psychosocial Oncology, we are pleased to present the Abstracts from the 2023 Annual Conference, titled "Co-designing Psychosocial Oncology: Optimizing Outcomes for All". The conference was held in Montreal from 20 June 2023 to 22 June 2023. This conference brought together key stakeholders including multidisciplinary professionals from nursing, psychology, psychiatry, social work, spiritual care, nutrition, medicine, rehabilitation medicine, occupational health and radiation therapy for both adult and pediatric populations. Participants included clinici

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… Preliminary Results of the PIVOT Group Intervention for People in Their 30s and 40s Navigating the Ways Cancer Changes Life Plans Dana Male 1,2 , Sara Beattie 1,2 , Perri Tutelman 1,2 , Fiona Schulte 1,2 , Jennifer Pink 3 , Jessie Moorman 2 and April Boychuk 2 University of Calgary, Calgary, Canada Alberta … Participants were AYAs with cancer (currently 16–29 years, diagnosed ≥ 15 years) who were treated at the Alberta Children’s Hospital or Tom Baker Cancer Centre in Calgary, AB. To be eligible, patients had to be currently receiving treatment or be within 5 years of treatment completion. …

Elective Surgical Care Pathways Are Associated With Lower Fracture Rates at Presentation and Contribute to Superior Clinical Outcomes in Metastatic Bone Disease.

BACKGROUND AND OBJECTIVES: Metastatic bone disease (MBD) often necessitates orthopaedic surgical intervention, which occurs through either emergent or elective care pathways. This study compared post-operative outcomes between patients undergoing elective versus emergent surgery for MBD involving the pelvis and appendicular skeleton. METHODS: We performed a retrospective, multicenter, propensity-matched cohort study of patients who underwent surgery for MBD. Emergent surgery was defined as an unplanned admission followed by unscheduled surgery, while elective surgery referred to cases with an

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… Results A total of 558 patients with MBD of the long bones or pelvis were treated with orthopaedic surgery across nine institutions in southern Alberta, Canada over a 15‐year period. … This study was approved by the Health Research Ethics Board of Alberta Cancer Committee (HREBA. CC‐20‐0335). Conflicts of Interest The authors declare no conflicts of interest. …

Abstracts of the Cell Therapy Transplant Canada 2024 Annual Conference.

On behalf of Cell Therapy Transplant Canada (CTTC), we are pleased to present the Abstracts of the CTTC 2024 Annual Conference. The conference was held on 1-3 May 2024 in beautiful Victoria, British Columbia, at the Victoria Conference Centre, and attracted 293 in-person delegates and five virtual attendees. Several plenary sessions were held on topics such as gene therapy for hemoglobin disorders, optimizing donor selection, graft-versus-host disease (GvHD) strategies, collaborative care, survivorship, graft failure, and CAR-T therapy. Poster authors presented their work during a lively and e

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… Acker 1,2 and Esme Dijke 1,4,5,6 Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada PanTHERA CryoSolutions Inc, Edmonton, AB, Canada Department of Pediatrics, University of Alberta, Edmonton, AB, Canada Alberta Transplant Institute, Edmonton, AB, Canada … , Edmonton, AB, Canada Children’s Heart Centre, British Columbia Children’s Hospital, Vancouver, BC, Canada Alberta Cell Therapy Manufacturing, University of Alberta, Edmonton, AB, Canada Cumming School of Medicine, University of Calgary, Calgary, AB, Canada Background: CD4 + T regulatory cells ( …

В канадском продольном исследовании по проблемам старения было проведено исследование с целью выявления взаимосвязи между неблагоприятным детским опытом и иммунопосредованным воспалительным заболеванием.

ЦЕЛЬ: Неблагоприятный детский опыт (АСЕ) непоследовательно учитывается в качестве факторов риска для иммунных подстрекательских заболеваний (ИМИД). Мы провели оценку того, отличается ли связь между ACE и болезнями между IMID и другими хроническими заболеваниями. DESIGN: Ретроспективное исследование по вопросам контроля за делами. СИТТИНГ: Мы использовали данные Канадского продольного исследования по проблемам старения (CLSA), в котором за период с 2010 по 2015 год были привлечены участники в возрасте от 45 до 85 лет.В число участников входили 12 627 участников КЛСА: 2 102 человека, сообщившие

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… Western provinces include British Columbia, Alberta, Saskatchewan, and Manitoba. Atlantic provinces include Nova Scota, New Brunswick, Prince Edward Island, and Newfoundland. … Western provinces include British Columbia, Alberta, Saskatchewan, and Manitoba. Atlantic provinces include Nova Scota, New Brunswick, Prince Edward Island, and Newfoundland. …

Канадский совместный проект по генетической восприимчивости к многочисленным склерозовым группам населения и этиологии болезней.

В предыдущих генетических и эпидемиологических исследованиях анализировались подгруппы канадского Совместного проекта по генетической приемлемости для группы пациентов с множественным склерозом (CCPGSMS), однако всеобъемлющий анализ населения, охваченного исследованиями, еще не проведен. ЦЕЛЬ: В этом ретроспективном исследовании рассматриваются модели множественного склероза (МС) 13,663 Члены групп, включая 4,821 лиц с НР или подозреваемых НР и 8,842 Члены семьи.Мы сгруппировали участников в эпидемиологические подгруппы по возрасту MSshore, клинической стадии диагностики, типу симптомов при на

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… BC, British Columbia; AB, Alberta; SK, Saskatchewan; MB, Manitoba; ON, Ontario; QC, Quebec; NL, Newfoundland; NB, New Brunswick; NS, Nova Scotia. To interpret differences between subsets of persons with MS, disability status was examined using ARMSS scores. … Proband incidences in this study were proportionally comparable to the relative populations of most Canadian provinces, apart from Alberta and Nova Scotia. …

метрики соотношений на основе пропорциональности при подсчете данных о составе.

Составные данные включают векторы, описывающие составные части целого. Данные, полученные с помощью различных -омикических платформ, таких, как 16S и RNA, носят составный характер. В таких данных корреляции между характеристиками первичных счетов не имеют сколько-нибудь значимого толкования. Для решения этой проблемы были сформулированы критерии пропорциональности. Однако имманентная погрешность возникает тогда, когда эти метрики рассчитываются эмпирически на основе показателей, основанных на подсчете, из-за изменчивости глубин считываемого материала. Мы подсчитали погрешность, введенная путем

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… Simona Veniamin, Department of Medicine, Division of Gastroenterology, University of Alberta, Alberta, T6G 2B7, Canada. Juan Jovel, Faculty of Veterinary Medicine, University of Calgary, Alberta, T2N 1N4, Canada. … , Alberta, T6G 2R3, Canada. …

A Retrospective Study of Chronic Kidney Disease Burden in Saskatchewan's First Nations People.

BackgroundChronic kidney disease is more prevalent among First Nations people than in non-First Nations people. Emerging research suggests that First Nations people are subject to greater disease burden than non-First Nations people.ObjectiveWe aimed to identify the severity of chronic kidney disease and quantify the geographical challenges of obtaining kidney care by Saskatchewan's First Nations people.DesignThis study is a retrospective analysis of the provincial electronic medical record clinical database from January 2012 to December 2013.SettingThe setting involved patients followed by th

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… Distance traveled by each client to access services was estimated courtesy of a Geographic Information System analyst in the First Nations and Inuit Health Branch (FNIHB) of Health Canada, Alberta Region. … Previous work by Gao et al in 2007 in Alberta reported on rates of CKD in First Nations communities, identifying First Nations peoples as those registered under the Federal Indian Act; however, it is unclear by which First Nations indicator was used to confirm registration. …

Afri-Can Forum 2 : Johannesburg, South Africa. 16-18 February 2015.

A1 Introduction to the 2nd synchronicity forum of GHRI/CHVI-funded Canadian and African HIV prevention and vaccine teams O1 Voluntary medica … are associated with peripheral CXCR6+ NK cell subsets Moustapha Mbow, Sabelle Jallow, Moussa Thiam, Alberta Davis, Assane Diouf, Cheikh T. Ndour, Moussa Seydi, Tandakha N. Dieye, Souleymane Mboup, Martin Goodier, Eleanor Rilley, Assan Jaye O11 Profiles of resistance: Local innate mucosal immunity to HIV-1 in commercial sex workers Xiao-Dan Yao, RW. Omange …

The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer.

Breast cancer is the leading cause of cancer-associated deaths in women worldwide. Clinical biomarkers give information on disease progression and identify relevant biological pathways. A confounding factor that uncouples markers from disease outcome is the ability of tumor cells to mutate and evade clinical intervention. Therefore, we focussed on apoptotic genes that modulate tumor regression. Using gene and tissue microarray analyses, we identified an association of Bcl-2 interacting killer (Bik) with poor breast cancer prognosis. Bik prognostic ability was independent of Estrogen Receptor/P

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… Gene expression and tissue microarray analyses Pre-treatment tumor samples were accessed from the Alberta Cancer Research Biobank/CBCF Tumor Bank. Patient information was collected under research ethics board approval (HREB Biomedical). All patients received guideline based standard therapy. … SUPPLEMENTARY FIGURE AND TABLES Operating grants from the Alberta Institute for Health Research (AIHS)/Pfizer program (ISG, JRM), Alberta Cancer Foundation (ISG, JRM) and Canadian Breast Cancer Foundation (CBCF) Prairies/NWT Chapter (ISG) supported this research. …

Review of the utility of routine mortality reviews among deaths on General Internal Medicine wards in a Canadian tertiary care hospital.

BackgroundHospital morbidity and mortality reviews are common quality assurance activities, intended to uncover latent or unrecognised systemic issues that contribute to preventable adverse events and patient harm. Mortality reviews may be routinely mandated by hospital policy or for accreditation purposes. However, patients under the care of certain specialties, such as general internal medicine (GIM), are affected by a substantial burden of chronic disease, advanced age, frailty or limited life expectancy. Many of their deaths could be viewed as reasonably foreseeable, and unrelated to poor-

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… UAH is a large urban academic tertiary care Canadian hospital operated by Alberta Health Services (AHS) in Edmonton, Alberta, and is one of the city’s largest hospitals, serving a population of approximately 1.3 million people. … Table 1 Alberta Health Services clinical adverse event rating Grading | Description 1 | There were no clinical adverse events detected. 2 | There were no clinical adverse events detected. …

Recanalisation theraphy for acute ischemic stroke in cancer patients.

To date, very few studies focused their attention on efficacy and safety of recanalisation therapy in acute ischemic stroke (AIS) patients with cancer, reporting conflicting results. We retrospectively analysed data from our database of consecutive patients admitted to the Udine University Hospital with AIS that were treated with recanalisation therapy, i.e. intravenous thrombolysis (IVT), mechanical thrombectomy (MT), and bridging therapy, from January 2015 to December 2019. We compared 3-month dependency, 3-month mortality, and symptomatic intracranial haemorrhage (SICH) occurrence of patien

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… artery, middle cerebral artery, and extracranial internal carotid artery plus middle cerebral artery, i.e. tandem occlusion) or posterior (intracranial vertebral artery, basilar artery, and posterior cerebral artery) circulation as revealed by CT angiography (CTA); (2) symptoms onset within 6 h; (3) Alberta … Pexman JH Barber PA Hill MD Use of the Alberta stroke program early CT score (ASPECTS) for assessing CT scans in patients with acute stroke Am. J. Neuroradiol. 2001 22 1534 1542 11559501 PMC7974585 20. …

Exploring participant perceptions of a virtually supported home exercise program for people with multiple myeloma using a novel eHealth application: a qualitative study.

IntroductionSupervision, tailoring, and flexibility have been proposed as key program elements for delivering successful exercise programs for people with multiple myeloma (MM). However, no studies to date have evaluated the acceptability of an intervention employing these components. The aim of this study was to determine the acceptability of a virtually supported exercise program and eHealth application for people with MM.MethodsA qualitative description approach was used. One-on-one interviews were conducted with participants who completed the exercise program. Content analysis was used to

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… Funding GP was supported by the Government of Alberta through the Alberta Graduate Excellence Scholarship, by the Canadian Institutes for Health Research through the Sir Frederick Banting and Dr. … Ethics approval was received from the Health Research Ethics Board of Alberta: Cancer Committee on August 26 th , 2020 (HREBA.CC-20–0201). The study was registered at www.clinicaltrials.gov ( NCT04484714 ). …

Guidelines for the use of survivorship care plans: a systematic quality appraisal using the AGREE II instrument.

BackgroundSurvivorship care plans (SCPs) are written treatment summaries and follow-up care plans that are intended to facilitate communication and coordination of care among survivors, cancer care providers, and primary care providers. A growing number of guidelines for the use of SCPs exist, yet SCP use in the United States remains limited. Limited use of SCPs may be due to poor quality of these guidelines. The purpose of the study was to evaluate the quality of guidelines for SCP use, tools that are intended to promote evidence-based medicine.MethodsWe conducted a comprehensive search of th

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… Guideline | Country of origin | Focus | Target audience | Survivor group Alberta Health Services | Canada | Survivorship care | Oncology providers; family physicians | Breast American Cancer Society | United States | Survivorship care | None explicitly stated, but oncology practitioners implied | None … Alberta Health Services. Follow-up care for early-stage breast cancer: Clinical Practice Guideline BR-013 version 1. 2013. 20. Comprehensive Cancer Centre of the Netherlands. Cancer Survivorship Care: Nationwide Guideline, Version 1.0. 2011. 21. …

Acceptability and Effectiveness of a Fully Web-Based Nutrition and Exercise Program for Individuals With Chronic Disease During COVID-19: Randomized Controlled Trial.

BackgroundIn-person nutrition and exercise interventions improve physical function in chronic diseases, yet the acceptability and effectiveness of web-based delivery, especially with different levels of personnel support, require further investigation.ObjectiveThis study aims to evaluate a web-based nutrition and exercise intervention delivered entirely digitally from recruitment to trial completion.MethodsA randomized controlled trial was conducted using the Heal-Me version 1 platform across 2 levels of personnel support (Light and Intensive). Eligible adults with a history of cancer, chronic

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… Recruitment Study advertisement and recruitment were carried out by the digital distribution of recruitment materials by frontline staff involved in oncology (Alberta Cancer Exercise), pulmonary (Breathe Easy), and posttransplant lung or liver rehabilitation programs (University of Alberta Hospitals … ) in Edmonton, Alberta. …

Mobilization and Exercise Intervention for Patients With Multiple Myeloma: Clinical Practice Guidelines Endorsed by the Canadian Physiotherapy Association.

ObjectiveIndividuals with multiple myeloma (MM) often have reduced functional performance due to the cancer itself or as a direct side effect of cancer treatments. Physical therapy is a part of cancer rehabilitation; however, no guidelines are available to provide information and direction for physical therapists managing patients with MM. The goal of this guideline is to provide recommendations based on a systematic review and consensus process that physical therapists can use to manage patients with MM.MethodsA systematic review of the literature published until August 2018 was performed in

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… Of these, 4 physical therapists were from Ontario, 2 from Winnipeg, 2 from Québec, and 1 from British Columbia and 1 from Alberta. The physical therapists’ work experience ranged from 4 to 27 years with tremendous experience working with patients with MM. … Alberta Health Services . Management of neutropenia. Alberta, Canada: Alberta Health Services. Accessed August 11, 2020. https://www.albertahealthservices.ca/assets/info/hp/cancer/if-hp-cancer-guide-adult-febrile-neutropenia.pdf . 19. Anaissie M. …

Abstracts of the 5(th) Cachexia Conference, Barcelona, Spain, December 5-8, 2009.

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… Baracos 2 , Marion Perrine 3 , Marina Mourtzakis 4 1 Alberta Institute for Human Nutrition, University of Alberta, Edmonton, AL, Canada; 2 Department of Oncology, University of Alberta, Edmonton, AL, Canada; 3 UNILEVER Deutschland GmbH, Centre of Excellence Dry Foods, Heilbronn, Germany; 4 Department … Baracos 2 1 Department of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, AL, Canada; 2 Division of Palliative Care Medicine, University of Alberta/Cross Cancer Institute, Edmonton, AL, Canada; 3 School of Health Information Science, University of Victoria, Victoria, BC …

Treatment preferences of patients with relapsed and refractory multiple myeloma: a qualitative study.

BACKGROUND: Multiple myeloma is a haematological malignancy characterized by significant morbidity and mortality. This study sought to develop an in-depth understanding of patients' lived experiences of relapsed or refractory multiple myeloma (RRMM) and its treatment, and to identify which features of treatment were most important to them. METHODS: Qualitative interviews and focus groups (FGs) were conducted with 32 people living with RRMM across Canada. In Phase 1, interviews focused on participants' accounts of their experiences with the disease and its treatment and laid the groundwork for

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… Interview participants were recruited from across Canada and participated in in-depth semi-structured one-on-one interviews by phone; follow-up focus groups were conducted in regions (Alberta, Ontario and Quebec) where interview participants had indicated they would be able to attend. … In-person focus groups were held in three cities in three Canadian provinces (Alberta, Ontario and Quebec). Each focus group lasted approximately 90 min. Based on the results of our interviews, we derived a list of features that we presented to focus group participants. …

Inequities in access to palliative and end-of-life care in the black population in Canada: a scoping review.

BackgroundImproving equity and early access to palliative care for underserved populations in Canada is a priority. Little is known regarding access to palliative and end-of-life care in the Black population.MethodsWe undertook a scoping review using the framework by Arksey and O'Malley to identify knowledge, access gaps, and experiences of palliative and end-of-life care among Blacks living with life-limiting illnesses in Canada. Primary studies, discussion papers, books, and reports were considered eligible. We followed a comprehensive search strategy developed by an information scientist. S

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… These cities are found in three main provinces: Ontario, Quebec, and Alberta. More than half of Canada’s Black population reported Ontario as their home, with the largest number found in Toronto [ 16 ]. … Acknowledgements We are grateful for the funding support of the University of Alberta Endowment Fund for the Future: Support for the Advancement of Scholarship (EFF-SAS) Research Fund. …

Post hip fracture orthogeriatric care-a Canadian position paper addressing challenges in care and strategies to meet quality indicators.

INTRODUCTION: Osteoporosis is a major disease state associated with significant morbidity, mortality, and health care costs. Less than half of the individuals sustaining a low energy hip fracture are diagnosed and treated for the underlying osteoporosis. OBJECTIVE: A multidisciplinary Canadian hip fracture working group has developed practical recommendations to meet Canadian quality indicators in post hip fracture care. METHODS: A comprehensive narrative review was conducted to identify and synthesize key articles on post hip fracture orthogeriatric care for each of the individual sections

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… This report is also guided by key quality indicators for hip fracture care provided by Health Quality Ontario (HQO) and Alberta Health Services (AHS) [ 2 , 6 ]. … See Alberta Health Services regarding post-discharge instructions (available here: http://www.rehabcarealliance.ca/uploads/File/Initiatives_and_Toolkits/QBP/UPDATED_November_2017-_Hip_Fracture_QBP_Rehabilitative_Best_Practices_Framework.pdf ) [ 110 ]. …

How should multiple myeloma research change in a patient-oriented world? Findings and lessons from the pan-Canadian myeloma priority setting partnership.

BACKGROUND: Over the last decade there has been considerable research into the treatment, management, and quality of life of people living with multiple myeloma. However, there has been limited investigation into topics deemed important to patients and caregivers within this community. We conducted a James Lind Alliance Priority Setting Partnership to establish the 'Top 10 Priorities for Myeloma Research', informed by patient and public partners. METHODS: A research team and steering group were established in 2019 to conduct the myeloma priority setting partnership. Steering group members inc

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… (0.84%) Arab or West Asian | 3 (0.51%) Black | 3 (0.51%) Chinese | 3 (0.51%) Filipino | 1 (0.17%) Japanese | 1 (0.17%) Korean | 2 (0.34%) Latin American | 2 (0.34%) South Asian | 1 (0.17%) South East Asian | 5 (0.84%) White | 426 (71.72%) Other | 12 (2.02%) Not Specified | 138 (23.23%) Province | Alberta … 100%) Mean age (SD) | 53.29 (13.73) Race (note: participants could check all that applied) | South Asian | 2 (8.70%) Black | 1 (4.35%) Indian | 1 (4.35%) Arab or West Asian | 3 (13.04%) South East Asian | 1 (4.35%) Latin American | 1 (4.35%) White | 15 (65.22%) Not specified | 1 (4.35%) Province | Alberta …