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[Variability in scabies mites Sarcoptes scabiei De Geer (Acariformes, Sarcoptidae) in relation to scabies epidemiology. 1. A statistical model of female variability].

Individual variability of 235 grain mite females from Moscow and the Moscow Province was studied. The data were processed on a computer. Body proportions were used as a representative dimension index. The size of proterosomal scutellum was stable. A map of the chaetoid cover of notum is given, and its variability was studied. Statistical analysis of all signs was made. Frontal chaetoid and sejugal sections and the number of caudal chaetoids are stable. Naked, middle and abdominal chaetoid sections are the most variable. Linear sizes of naked section and the number of chaetoid sets on middle an…

[Epidemiology of spontaneous nasal, ear and throat bleedings].

UNLABELLED: Bleeding is a life-threatening condition, requiring an urgent care. The first line of treatment this kind of patients is ambulance doctors (emergency medical team). Spontaneous bleeding (SB), in this case, don't have a traumatic agent (including surgical trauma). STUDY OBJECTIVE: The purpose of this study was to evaluate spontaneous bleeding epidemiological profile of Moscow city emergency service. METHODS: Study included statistical reports of Moscow city emergency services medical teams (EMT) were servicing adults. We analyzed total number of calls and number of EMT calls to pa…

[The effect of polymorphisms C677T and 1298 gene MTHFR on the reproductive function of men].

UNLABELLED: References. Disturbances of spermogram parameters are associated with infertility in men and are determined by polymorphisms of many genes involved in spermatogenesis. Folate metabolism plays an important role in spermatogenesis, as it is involved in the synthesis, repair and methylation of DNA. OBJECTIVE: the distribution of C677T (rs1801133) and A1298C (rs1801131) polymorphisms of the MTHFR gene among infertile and fertile men in the Moscow region and to identify a possible Association of these polymorphisms with the risk of pathospermia. MATERIALS AND METHODS: the study includ…

[Direct human DNA damage by unfavorable environmental and climatic factors].

AIM: To study the impact of simulated climatic conditions of the 2010 summer in Moscow on the telomere repeats of chromosomes in human blood cells. MATERIALS AND METHODS: The climatic conditions of July-August 2010 in Moscow were simulated at the Medical Technical Complex, Institute of Biomedical Problems, Russian Academy of Sciences. The relative length of the telomeric repeats of blood cell chromosomes from 6 apparently healthy volunteers was measured by quantitative real-time polymerase chain reaction. RESULTS: These conditions were ascertained to lead to a statistically significant decli…

[Methodological recommendations for surgical care in patients with hemophilia A receiving prophylactic therapy with emicizumab].

Methodological recommendations for surgical care in patients with hemophilia A receiving prophylactic therapy with emicizumab. Recommendations of the expert group. Moscow, 2024.

[Classification of coagulase-negative staphylococci isolated from urologic diseases].

A total of 174 strains of coagulase-negative staphylococci were isolated from the urine of urological patients in the USSR (Moscow) and the GDR (Wernigerode). Three schemes were used for identifying the species of the cultures (S. epidermidis and S. saprophyticus): the scheme proposed by the International Subcommittee for Taxonomy of Staphylococci and Micrococci (1976), the scheme of Digranes and Oeding (1975) and the scheme proposed by the authors of the present work. The use of the above-mentioned schemes allowed to identify 25, 33 and 68 per cent of the strains respectively. S. epidermidis …

[Method of endonasal endoscopic dacryocystorhinostomy with plastic stoma formation].

The article presents modern methods of surgical treatment of chronic dacryocystitis, a brief historical review of various options for endonasal endoscopic dacryocystorhinostomy is carried out. The method of plastic seamless formation of dacryocystostomy, which does not require intubation of the lacrimal passages and/or using of silicone stoma dilators, is described. Between 2010 and 2019 at The State Budgetary Healthcare Institution of Moscow Area Moscow regional research clinical institute n.a. M.F. Vladimirskiy, according to the developed technique, 32 patients (32 eyes) with chronic dacryoc…

[Seeding efficiency of the causative agent of dysentery as an index of the intensity of the epidemiologic process].

A study was made of the character and extent of interrelationship between the indices of dysentery morbidity and the indices of the seeding efficiency of dysentery bacilli persons who did not apply for medical aid. Establishment of such interrelationship permitted the authors to suggest the use of a more objective index of the seeding efficiency of dysentery bacilli, along with morbidity indices, for the assessment of the intensity of the epidemic process in this infection. On the basis of investigations carried out the authors came to the conclusion that a tendency to the increase of dysenter

[The epidemiological-epizootiological subdivision of the nosogeographic range of trichinosis].

The prevalence of trichinosis was analyzed among human beings and animals in Moscow Province over 50 years (1946-1996). A total of 7022 domestic, synanthropic, and wild carnivorous animals were incompletely helminthologically dissected. Enzyme immunoassay revealed diagnostic Trichinella antigen antibody titers in 45.4% of 544 examinees during outbreaks and at their intervals, as well as in 0.58% of domestic pigs of different property forms. Trichinella larvae were found in domestic pigs (0.13%), dogs (12.3%), cats (12.9%), hunting and fur-bearing (wild boars (2.0%), wolves (38.8%), red foxes (…

В поисках интригующих головоломок.

Этот специальный обзор представляет собой своего рода научную автобиографию, основанную на презентации на симпозиуме "Вирусы: открытие большого и малого", проведенном в ознаменование 90-летия автора (Москва, март 2019 года).

Совпадение в аннотации оригинала
This Invited Review is a kind of scientific autobiography based on the presentation at the Symposium "Viruses: Discovering Big in Small" held in honor of the author's 90th birthday (Moscow, March 2019).

[Contact granuloma of the larynx].

The authors analyse the results of clinical examination of patients with contact granuloma of the larynx treated in Moscow and Erlangen (Germany) clinics. Etiology, pathogenesis of this disease and treatment policy are discussed.

[The age-related structure of an Ixodes ricinus population studied by using a rapid anatomical method].

A rapid anatomic method for the assessment of the physiologic age of ticks and their virtual age was used in studies of the age structure of a natural population of I. ricinus in the Moscow region. The anatomic method was found quite fit for the purpose. The findings evidence that the age structure of I. ricinus (active imago) population is heterogeneous with variously directed seasonal fluctuations. In spring the structure is the youngest (up to 60% of imagoes are in the second age, 8 months) and in the fall the females are mainly old, just starting to get younger (up to 90% are in the third …

[Assessment of the effectiveness of different methoods of immunization with live plague vaccine EB in aerosol infections].

The work deals with the results of the comparative evaluation of the effectiveness of vaccines developed at the Sanitary Research Institute (Zagorsk) and the Mechnikov Research Institute for Vaccines and Sera (Moscow), as well as two methods of immunization against plague, by inhalation and subcutaneous injection, under the conditions of aerosol infection. The immunogenic effectiveness of both vaccines, when evaluated in terms of LD50, was shown to be approximately the same, but the animals immunized by the inhalation method with the vaccine developed at the Sanitary Research Institute proved …

Russian experience in screening, analysis, and clinical application of novel interferon inducers.

This review describes a long-standing experience of screening for interferon (IFN) inducers in Russia. IFN inducers represent a special group of potential antiviral compounds. The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-alpha/beta produc…

State of transition to Ministry of Health governance of prison healthcare in the Council of Europe region.

OBJECTIVES: This study aimed to examine timebound prison healthcare governance amendments and current structures in Europe two decades after the World Health Organization (WHO) Declaration on Prison Health as part of Public Health adopted in Moscow on 24 October 2003 (Moscow Declaration), which recommended prison health care be closely linked with public health systems to ensure quality prison health care, connected health surveillance, and continuity of care. STUDY DESIGN: We present here a regional evolutionary mapping of the Council of Europe Member State transfer of prison healthcare gove…

[Prevalence of some modified cardiovascular risk factors among young students].

AIM: To estimate the prevalence of some modified cardiovascular risk factors (RFs) among the students of two Moscow higher education institutions to further test the technology of individual medical prevention counseling. SUBJECTS AND METHODS: A questionnaire survey was conducted among 1912 first-year students (boys and girls, mean age 17.7 years) from 2 Moscow higher education institutions to reveal physical activity levels, smoking status, alcohol abuse, and food addictions. RESULTS: Almost one third of the students (mainly girls) lead a sedentary lifestyle. The mean age at onset of smokin…

[A case of tubercular laryngopharyngitis diagnosed by biopsy].

A 47-year-old man had ulcero-necrotic pharyngitis examined and treated without effect in various Moscow hospitals for 3 months. The diagnosis was established after histologic and bacteriologic examination of the biopsy.

[Current features of a mastoiditis course].

A clinical course of mastoiditis according to recent literature data is characterized, therapeutic policy is discussed. The results of mastoidectomies made in the ENT clinic of the Moscow State Medical University in 2004-2007 are reviewed retrospectively.

Birth month as a risk factor of allergic diseases: Analysis of database of about 50 thousand children.

BACKGROUND: The season of birth is a factor influencing the child during the neonatal adaptation period and potentially affecting the risk of allergies. The objective of this study was to ascertain the association between the month of birth and the subsequent development of allergic diseases in Moscow children, Russia. METHODS: in 2024 the de-identified data from medical records and parental questionnaires of 49,857 children under the age of 18 was retrieved from the Moscow Unified Medical Information and Analytical System. The database contained the information regarding the presence of atop…

[The influence of psychological and psychosomatic disorders on population mortality rates].

The importance of the psychological-and-social factors as the key reasons for the high prevalence of cardiac diseases, hypertension, ulcers, hepatocirrhosis, alcoholic psychosis and of suicides was pointed out on the basis of an analysis of the death rate among Moscow residents.