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Минимальная информация для исследований внеклеточной везиклетки (MISEV2023): от базовых до передовых подходов.

Внеклеточные везиклолы (ЭМ) с помощью своего сложного груза могут отражать состояние клетки их происхождения и изменять функции и фенотипы других ячеек. Эти особенности свидетельствуют о значительном биомаркировании и терапевтическом потенциале и вызывают широкий интерес, о чем свидетельствует постоянное увеличение числа научных публикаций об ЭМ за год. Значительные успехи были достигнуты в области ЭВМ, а также в понимании и применении биологии ЭМ. Вместе с тем сохраняются препятствия на пути реализации потенциала ЭМ в различных областях - от базовой биологии до клинического применения - в свя

The Fifth International Meeting of ISEV, ISEV2016, Rotterdam, The Netherlands, 4 - 7 May, 2016.

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… OPW1.3=PF6.01 Characterization of EVs by flow cytometry John Tigges, Camacho Virginia and Toxavidis Vasilis: Flow Cytometry Science Center, Center for Extracellular Vesicle Research, Beth Israel Deaconess Medical Center, Boston, USA Characterization of extracellular vesicles (EVs) is greatly impeded …

Herpes Zoster in Aging Patients: Risk Factors and Prevention Strategies.

Herpes zoster (HZ), also known as shingles, is caused by varicella-zoster virus reactivation and can lead to long-term complications such as postherpetic neuralgia (PHN). Risk of HZ and related complications increases with age, presence of chronic conditions, and immunosuppression. The United States (US) has an increasingly aging and multimorbid population; therefore, knowledge of risk factors and prevention opportunities for HZ are of critical importance to inform broad efforts to prevent this disease. To consolidate information on risk factors for adults aged ≥50 years and opportunities to a

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… The association between healthcare access and shingles vaccination among older adults in Virginia, United States. PLoS One . 2025;20(4):e0316429. doi: 10.1371/journal.pone.0316429 102. Vogelsang EM, Polonijo AN. Scarier than the flu shot? …

Cannabis, One Health, and Veterinary Medicine: Cannabinoids' Role in Public Health, Food Safety, and Translational Medicine.

Public health is connected to cannabis with regard to food, animal feed (feed), and pharmaceuticals. Therefore, the use of phytocannabinoids should be examined from a One Health perspective. Current knowledge on medical cannabis treatment (MCT) does not address sufficiently diseases which are of epidemiological and of zoonotic concern. The use of cannabinoids in veterinary medicine is illegal in most countries, mostly due to lack of evidence-based medicine. To answer the growing need of scientific evidence-based applicable medicine in both human and veterinary medicine, a new approach for the

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… A feasibility study of industrial hemp on Virginia commercial poultry production. Senior Honors Projects, 2010-current. JMU Scholarly Commons 716. [accessed November 19, 2019]. Published May 4, 2019. Available at: https://commons.lib.jmu.edu/honors201019/716 . 34. US Food & Drug Administration. …

Резюме научных материалов, представленных ГКОМ 2019 : Берлин, Германия. 27 - 30 Март 2019

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Устные доклады

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… Luke’s/Rocky Mountain Hospital for Children, Denver, CO, United States 6 Ankara ARTES Spine Center, Ankara, Turkey 7 University of Virginia Medical Center, Charlottesville, VA, USA 8 Schulthess Klinik, Zürich, Switzerland 9 Hospital for Special Surgery, New York, NY, USA 10 Bordeaux University Hospital …

Иммунотерапевтический ландшафт амиотропического бокового склероза: библиометрический анализ тенденций в области исследований, приоритетов в области перевода и сетей сотрудничества (см.2006-2025).

Амиотрофный боковой склероз (ALS) по-прежнему является серьезной терапевтической проблемой, при этом иммунная диагностика все чаще признается в качестве одного из важнейших факторов развития заболеваний. Несмотря на обширные механистические исследования, никакой иммунотерапевтический подход не привел к последовательному изменению болезней, в связи с чем возникают вопросы о том, отражает ли этот переводный пробел биологическую сложность или структурную несогласованность в исследовательской экосистеме. Чтобы охарактеризовать интеллектуальную эволюцию исследований иммунотерапевтии ALS, определить

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… Virginia Lee (2020 Breakthrough Prize laureate) at the University of Pennsylvania. His research focuses on the pathological and physiological functions of disease-associated proteins in neurodegenerative disorders using electrophysiology, live-cell imaging, and in vivo techniques. Dr. …

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia.

AbstractLineage switch (LS), defined as the immunophenotypic transformation of acute leukemia, has emerged as a mechanism of relapse after antigen-targeted immunotherapy, which is associated with dismal outcomes. Through an international collaborative effort, we identified cases of LS after a host of antigen-targeted therapies (eg, CD19, CD22, CD38, and CD7), described how LS was diagnosed, reviewed treatment approaches, and analyzed overall outcomes for this form of postimmunotherapy relapse. Collectively, 75 cases of LS were evaluated, including 53 (70.7%) cases of B-cell acute lymphoblastic

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… F.E.C. is a consultant with SPD Oncology, Amgen, CTI BioPharma, AbbVie, MorphoSys, Association of Community Cancer Centers, PharmaEssentia, Bristol Myers Squibb, Geron, Sobi, and DAVA Oncology; received clinical trial grant support (principal investigator) to the University of Virginia from Amgen, Celgene …

Всемирный конгресс молекулярного воображения 2022.

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PROCEEDINGS 32nd Symposium ESVN-ECVN WROCLAW, POLAND 12th-14th September 2019. Selected research communications of the 32nd Symposium of the ESVN-ECVN Wroclaw, Poland 12th to 14th September 2019.

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Совпадение в полном тексте источника
… Debinski 2 1 Department of Neurology and Neurosurgery, Virginia‐Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA, 2 Brain Tumor Center of Excellence, Wake Forest Baptist Medical Center Comprehensive Cancer Center, Winston‐Salem, NC, USA, 3 Department of Surgical and Radiological … York 1 1 Department of Surgical and Radiological Sciences, University of California, Davis, CA, USA, 2 Veterinary Medical Teaching Hospital, University of California, Davis, CA, USA, 3 Department of Small Animal Clinical Sciences, Virginia Tech, Blacksburg, VA, USA, 4 Department of Pathology, Microbiology …

ISEV2018 абстрактная книга

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… 2 – EVs and the Immune System Chairs: Francesc Borras; Esther Nolte’t-Hoen Location: Room 5 10:45–12:15 OT02.01 Exosomal transfer of microRNAs during immune synapsis contributes to the fine-tuning of immune responses Lola Fernández Messina 1 ; Ana Rodríguez-Galán 2 ; Francisco Sánchez-Madrid 1 ; Virginia …

Abstracts of the 19th International Congress on Neuromuscular Diseases 7th – 11th July 2026

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… University Hospitals-Cleveland Medical Center, Case Western Reserve University, Cleveland, United States. 18 Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, United States. 19 Stanford Neuroscience Health Center, Palo Alto, United States. 20 Department of Neurology, Virginia …

Электронные постеры

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… Anterior cervical hybrid constructs reduce upper adjacent segment hypermobility compared to anterior cervical discectomy and fusion Fenil Bhatt 1 , Lindsay Orosz 2 , Tarek Yamout 1 , Christopher Good 1 , Anthony Bucci 2 , Brandon Allen 2 , Thomas Schuler 1 , Ehsan Jazini 1 , and Colin Haines 1 1 The Virginia …

Е-постеры.

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2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference.

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… CT of the liver showing multiple focal lesions (20) Submission ID#792474 A Late Presentation of MPO Deficiency Farah Khan, MD 1 , Brant Ward, MD, PhD 2 1 Allergy/Immunology Fellow/Virginia Commonwealth University 2 Assistant Professor of Medicine/Virginia Commonwealth University Abstract/Case Report …

USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer.

BACKGROUND: Radiotherapy is a major modality for esophageal cancer (ESCA) treatment, yet radioresistance severely hampers its therapeutic efficacy. Ubiquitin-specific peptidase 14 (USP14) is a novel deubiquitinase and can mediate cancer cells' response to irradiation, although the underlying mechanism remains unclear, including in ESCA. METHODS: To evaluate the expression of USP14 in ESCA tissues or cells, we used RNA-Seq, immunoblotting, co-immunoprecipitation (Co-IP), ubiquitination, quantitative real-time polymerase chain reaction (qRT-PCR), and immunofluorescence assays in this investigat

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… Human ESCA cell lines TE-10 and KYSE-150 were purchased from ATCC (Manassas, Virginia, USA). Human ESCA cell lines TE-12 and OE-19 were purchased from Procell (Wuhan, China). All cell lines were cytogenetically tested by STR-Promega and authenticated. …

Lipocalin 2-not only a biomarker: a study of current literature and systematic findings of ongoing clinical trials.

Lipocalin 2 (Lcn2), also known as neutrophil gelatinase-associated lipocalin, is an innate immune protein encoded by the LCN2 gene. In this study, we investigated various roles and functions of Lcn2 characterized in a systems-based format and evaluated its therapeutic potentials and clinical relevance for diagnosis and prognosis. An additional systematic presentation was presented for 70 ongoing clinical trials utilizing Lcn2 in the diagnostic and prognostic setting as a key outcome measure. With trials being conducted through December 2030, Lcn2 will become all the more relevant given its ass

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… : none (open label); primary purpose: basic science | May 2023 | Imperial Clinical Research Facility, London, UK NCT05358171 | 42 | Other | Interventional | Allocation: randomized; intervention model: parallel assignment; masking: single (outcomes assessor); primary purpose: prevention | Jun 2024 | Virginia …

ISEV2021 Abstract Book

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RESEARCH COMMUNICATIONS OF THE 34th ECVIM-CA CONGRESS.

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… Borgarelli 4 1 Virginia Maryland College of Veterinary Medicine Small Animal Clinical Science, Blacksburg, VA, United States; 2 Virginia Maryland College of Veterinary Medicine Small Animal Clinical Science, Blacksburg, VA, United States; 3 NorthStar Vets, Robbinsville, NJ, United States; 4 Virginia … Paranjape 2 1 Virginia‐Maryland College of Veterinary Medicine Department of Small Animal Clinical Sciences, Blacksburg, United States; 2 Virginia‐Maryland College of Veterinary Medicine, Blacksburg, United States Transesophageal echocardiography (TEE) can be used for estimating cardiac output (CO) …

Е-постеры.

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Совпадение в полном тексте источника
… Alessandro Versace 1 , Daniele Bongetta 1 , Elena Virginia Colombo 1 , Miriam Bua 2 , Tommaso Calloni 3 , Marilou Cavaliere 3 , and Roberto Assietti 1 1 ASST Fatebenefratelli Sacco, Milan, Italy 2 Università degli Studi di Milano, Milan, Italy 3 Università di Milano Bicocca, Milan, Italy Background … A Propensity Weight Adjusted Comparison Scott Daffner 1 , Joshua Bunch 2 , Douglas Burton 2 , Alden Milam 3 , Daniel Park 4 , Peter Whang 5 , John Jones 6 , and Howard An 7 1 West Virginia University, Morgantown, USA 2 University of Kansas Medical Center, Kansas City, USA 3 OrthoCarolina, Charlotte …