Результаты поиска

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990-2019: An analysis of the Global Burden of Disease Study 2019.

BACKGROUND: The burden of heart failure (HF) is high globally, but information on its burden in the Eastern Mediterranean Region (EMR) is limited. This study provides a systematic analysis of the burden and underlying causes of HF in the EMR, including at the country level, between 1990 and 2019. METHODS: We used the 2019 Global Burden of Disease (GBD) data for estimates of prevalence, years lived with disability (YLDs), and underlying causes of HF in the EMR. Age-standardised prevalence, YLDs, and underlying causes of HF were compared by 5-year age groups (considering 15 years old and more),…

Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia.

BACKGROUND: In the Mediterranean and Black Sea Region, arbovirus infections are emerging infectious diseases. Their surveillance can benefit from one health inter-sectoral collaboration; however, no standardized methodology exists to study One Health surveillance. METHODS: We designed a situation analysis study to document how integration of laboratory/clinical human, animal and entomological surveillance of arboviruses was being implemented in the Region. We applied a framework designed to assess three levels of integration: policy/institutional, data collection/data analysis and disseminati

The Analysis of Trends of Preschool Child Stunting, Wasting and Overweight in the Eastern Mediterranean Region: Still More Effort Needed to Reach Global Targets 2025.

BACKGROUND: This study was undertaken to analyze and compare Eastern Mediterranean (EM) countries in achievement of WHO nutrition global targets for children growth indicators by 2025. METHODS: A total of 108 national surveys from 20 countries in EM region were analyzed to estimate the prevalence of stunting and wasting and 93 surveys to estimate the prevalence of overweight/obesity in children. These data were obtained from national surveys included in the WHO Global Database on Child Growth and Malnutrition. RESULTS: In EM region, the prevalence of childhood stunting was estimated to have

Estimated incidence, prevalence, mortality, and registration of childhood cancer (ages 0-14 years) in the WHO Eastern Mediterranean region: an analysis of GLOBOCAN 2020 data.

BACKGROUND: There is little evidence about childhood cancer burden in the WHO Eastern Mediterranean region (EMR). We aimed to provide an estimate of childhood cancer burden in the EMR, examine the connection between age-standardised mortality rate and level of income (gross domestic product [GDP] per capita), and reflect on the current status of childhood cancer registration in the EMR. METHODS: Using the GLOBOCAN 2020 data from the Cancer Surveillance Unit of the International Agency for Research on Cancer, we extracted data for childhood cancer (at ages 0-14 years) incidence, prevalence, an…

Associations of free, bioavailable and total 25-hydroxyvitamin D with neonatal birth anthropometry and calcium homoeostasis in mother-child pairs in a sunny Mediterranean region.

Sufficient vitamin D status is crucial for successful pregnancy and fetal development. The assessment of 25-hydroxyvitamin D (25(OH)D) concentrations is commonly used to evaluate vitamin D status. Our objective was to examine the interrelated biodynamics of maternal and neonatal total, free and bioavailable 25(OH)D in maternal-neonatal dyads at birth and their associations with homeostasis and neonatal birth anthropometry. We analysed a cohort of seventy full-term mother-child pairs. We found positive associations between all neonatal measures of vitamin D status. Maternal forms exhibited a si

Electronic Nicotine Delivery Systems Use Among Students in the Eastern Mediterranean Region: A Systematic Review and Meta-Analysis of 60 Studies on Prevalence and Socioeconomic Determinants.

BACKGROUND: The rapid global increase in Electronic Nicotine Delivery Systems (ENDS) use among youth is a pressing public health concern. However, comprehensive data for the Eastern Mediterranean Region (EMRO) remains sparse. This study aimed to conduct a systematic review and meta-analysis to determine the pooled prevalence of ENDS use among student populations in EMRO countries. METHODS: Following PRISMA guidelines, a systematic search was conducted across PubMed, Scopus, Web of Science, and Embase for studies published up to August 2025. Observational studies reporting the prevalence of cu…

Entomological Survey for the Detection of Sand Fly Fauna and Vector Species in the Cutaneous Leishmaniasis Endemic Area in East Mediterranean Region of Turkey, Mersin Province.

Cutaneous (CL) and visceral (VL) forms of leishmaniasis, transmitted by sand flies, are seen in all countries located in Mediterranean Basin including Turkey. In this study, we aimed to conduct an entomological survey for the detection of sand fly fauna and vector species in Mersin province, one of the important endemic areas for CL in Turkey. In total, 912 sand fly specimens were collected in 2010 and 2011 using CDC light traps. Nine Phlebotomus (Diptera: Psychodidae) and three Sergentomyia (Diptera: Psychodidae) species were detected. Of the collected Phlebotomus sand flies, P. sergenti Parr

Public health impact of the spread of Anopheles stephensi in the WHO Eastern Mediterranean Region countries in Horn of Africa and Yemen: need for integrated vector surveillance and control.

BACKGROUND: Anopheles stephensi is an efficient vector of both Plasmodium falciparum and Plasmodium vivax in South Asia and the Middle East. The spread of An. stephensi to countries within the Horn of Africa threatens progress in malaria control in this region as well as the rest of sub-Saharan Africa. METHODS: The available malaria data and the timeline for the detection of An. stephensi was reviewed to analyse the role of An. stephensi in malaria transmission in Horn of Africa of the Eastern Mediterranean Region (EMR) in Djibouti, Somalia, Sudan and Yemen. RESULTS: Malaria incidence in Hor…

Prevalence of injecting drug use and HIV, hepatitis B, and hepatitis C in people who inject drugs in the Eastern Mediterranean region: a systematic review and meta-analysis.

BACKGROUND: Considerable disease burden is attributed to injecting drug use (IDU). This regional systematic review and meta-analysis aimed to assess the prevalence of IDU and the characteristics of people who inject drugs in the 22 countries of the WHO Eastern Mediterranean region. METHODS: We conducted a systematic review and meta-analysis on the prevalence of IDU, estimation of the population size of people who inject drugs, the characteristics of people who inject drugs, commonly injected drugs, the prevalence of HIV, hepatitis C virus, and hepatitis B virus in people who inject drugs, and…

MEFV variant spectrum and exploratory in silico stratification of uncommon variants in 611 individuals tested for suspected familial Mediterranean fever in the Eastern Black Sea region of Türkiye.

BACKGROUND: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, caused by variants in the MEFV gene. Regional MEFV variant spectra differ across Türkiye. We characterised the MEFV variant spectrum in a single-centre series of individuals tested for suspected FMF in the Eastern Black Sea region and explored in silico stratification of uncommon variants. No standardised clinical diagnostic criteria were applied; the study is therefore framed as a molecular variant-spectrum study. METHODS: We retrospectively analysed MEFV next-generation sequencing (NGS) rep

Разработка генетической диверсификации в сортах кизилов (Crataegus azarolus L.) естественно растущих в восточной части Медитерранееанской области Турции с использованием морфологических, помологических и интерпретирующих последовательностей повторов маркеров.

БАКGROUND: Турция является местом проживания многих важных видов фруктов благодаря своей географической локации и экологии. Кизил (Crataegus azarolus L.) — один из этих важных видов фруктов, который очень полезен для здоровья человека. В настоящем исследовании в 2022 и 2023 годах были идентифицированы 125 доступов кизила из различных регионов генеральной коллекции кизила в Восточном Медиiterrаниане Турции. Настоящее исследование проводилось для обнаружения морфологических, помологических и молекулярно-генетических вариаций доступов. РЕЗУЛЬТАТЫ: Исследованные доступы показывали значительные ра

Совпадение в аннотации оригинала
BACKGROUND: Türkiye hosts many important fruit species due to its geographical location and ecology. Hawthorn, which is highly beneficial for human health, is one of these significant fruit species. In the present study, 125 accessions of Crataegus azarolus L. were identified from different regions of hawthorn germplasm in the Eastern Mediterranean region of…

Toxic Release Damage Distance Assessment Based on the Short-Cut Method: A Case Study for the Transport of Chlorine and Hydrochloric Acid in Densely Urbanized Areas in the Mediterranean Region.

The transportation of dangerous goods by road is the most accident-prone mode of transportation, even if accidents involving road transportation of dangerous goods are considered as a Low Probability and High Consequence event (LPHC event). However, several dangerous goods are transported by road networks, such as petroleum products and chemicals, which can generate major dangerous consequences such as spills, explosions, fires, or toxic clouds. In this context, this article presents a method to calculate and quickly quantify the sizes of impact zones characterized by high lethality and irreve

Indigenous Plasmodium vivax upsurge in the Eastern Mediterranean, Western Pacific, and South East Asia regions - beyond the constant culpability of climate change, COVID-19, and armed conflicts.

Controlling Plasmodium vivax presents greater challenges compared to Plasmodium falciparum. Here, we analyzed epidemiological data on indigenous P. vivax cases from the Eastern Mediterranean, Southeast Asia, and Western Pacific regions in recent years. Significant upsurges are observed in more than half of the countries within these regions. In Papua New Guinea and Yemen, the increase has been consistent since 2015, while others, including Indonesia and Pakistan, have experienced sharp rises between 2020 and 2023 (e.g., +100 % and +83.4 %). Notably, in countries like Thailand, initially target

Situational analysis of health systems for ear and hearing care in the World Health Organization (WHO) Eastern Mediterranean Region: A systematic review and evidence synthesis to inform national policies and strategies.

In the Eastern Mediterranean Region (EMR), 78.1 million people experience hearing loss of any degree, with 22.1 million having disabling hearing loss, projected to reach 51.7 million by 2050. Unless global action is taken, the worldwide burden could reach over 700 million people with disabling hearing loss by 2050. This systematic review presents the first comprehensive health systems analysis of ear and hearing care (EHC) in the region. Following PRISMA guidelines, we analysed 146 articles through the WHO health systems framework to identify systemic barriers to effective EHC integration. Our…

Updates on the Epidemiology of the Human T-Cell Leukemia Virus Type 1 Infection in the Countries of the Eastern Mediterranean Regional Office of the World Health Organization with Special Emphasis on the Situation in Iran.

BACKGROUND: The epidemiology and prevalence of the Human T-cell leukemia virus type-1 (HTLV-1) infection represent a recommended priority by global health agencies. An in-depth revision to update the status of this infection in countries including those of the Eastern Mediterranean Regional Office (EMRO) of the World Health Organization is hence required. METHODS: Ninety-seven studies evaluating the HTLV-1 infection in low- and high-risk populations in EMRO countries were retrieved from the international electronic databases and were used to assess the epidemiological status of the infection …

Atmospheric mercury speciation at the Monte Curcio GAW/GMOS high-altitude observatory: A multi-year (2015-2023) assessment of long-range transport and regional dynamics in the Central Mediterranean basin.

High-altitude stations provide unique insights into background chemistry, although decoupling long-range transport from local mountain dynamics remains challenging. This study presents a comprehensive, high-resolution, multi-year (2015-2023) record of TGM/GEM, GOM, and PBM at the Monte Curcio observatory. The station's strategic position is highly significant as it is located within the Mediterranean basin, a well-recognized climate and mercury hotspot, allowing for the observation of the free troposphere and regional boundary layer dynamics. Atmospheric transport and chemical dynamics were th

Investigating the Role of Functional Polymorphism of Maternal and Neonatal Vitamin D Binding Protein in the Context of 25-Hydroxyvitamin D Cutoffs as Determinants of Maternal-Neonatal Vitamin D Status Profiles in a Sunny Mediterranean Region.

Recent results indicate that dysregulation of vitamin D-binding protein (VDBP) could be involved in the development of hypovitaminosis D, and it comprises a risk factor for adverse fetal, maternal and neonatal outcomes. Until recently, there was a paucity of results regarding the effect of maternal and neonatal VDBP polymorphisms on vitamin D status during pregnancy in the Mediterranean region, with a high prevalence of hypovitaminosis D. We aimed to evaluate the combined effect of maternal and neonatal VDBP polymorphisms and different maternal and neonatal 25-hydroxyvitamin D (25(OH)D) cut-of…

Adherence to Mediterranean diet: a public health paradox.

Diet plays a fundamental role in our life starting from the earliest stages and throughout each phase of our existence. One diet that has ga … need for coordinated public health strategies aimed at correcting or reversing this shiftwithin the Mediterranean region itself to avoid the long-term economic and public health consequences.

A voluntary code of conduct for promoting adherence to the Mediterranean diet: rationale and propositions.

Throughout the Mediterranean region, adherence to the Mediterranean diet is decreasing especially among young people. The Mediterranean diet is the most studied dietary pattern with proven health benefits, especially regarding the prevention of non-communicable diseases at a time when their incidence is increasing worldwide. It has also been recognized as a sustainable diet model with multiple interdependent benefits on social, cultural, environmental, and economic dimensions. Faced with the challenge of promoting adherence to the Mediterranean diet, a Joint Med Diet Task Force of CIHEAM, FENS…

Fatty acid specific δ13C values reveal earliest Mediterranean cheese production 7,200 years ago.

The earliest evidence for cheese production in the Mediterranean is revealed by stable carbon isotope analyses of individual fatty acids in pottery residues from the Dalmatian coast of Croatia. Lipid residue data indicate the presence of milk in the earliest pottery, Impressed Ware, by 5700 cal. BCE (7700 BP). In contrast, by 5200 cal BCE (7200 BP), milk was common in refined Figulina pottery, meat was mostly associated with Danilo ware, cheese occurred in Rhyta, and sieves contained fermented dairy, representing strong links between specific function and stylistically distinctive pottery vess