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Резюме докладов 2017 Ежегодное совещание Общества общей внутренней медицины.

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33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018) : Washington, D.C., USA. 7-11 November 2018.

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… Acknowledgements Acknowledgement: Daniel Foundation of Alabama and Mayo Clinic Cancer Center ( CA015083 ; A.A.C-K.), University of Iowa and Mayo Clinic Lymphoma SPORE Developmental Research Program (P50 CA097274; A.P.) and the Predolin Foundation (A.A.C-K). … Acknowledgements Acknowledgement: Daniel Foundation of Alabama and Mayo Clinic Cancer Center ( CA015083 ; A.A.C-K.), University of Iowa and Mayo Clinic Lymphoma SPORE Developmental Research Program (P50 CA097274; A.P.) and the Predolin Foundation (A.A.C-K). …

Vitamin C Supplementation in the Treatment of Autoimmune and Onco-Hematological Diseases: From Prophylaxis to Adjuvant Therapy.

Vitamin C is a water-soluble vitamin introduced through the diet with anti-inflammatory, immunoregulatory, and antioxidant activities. Today, this vitamin is integrated into the treatment of many inflammatory pathologies. However, there is increasing evidence of possible use in treating autoimmune and neoplastic diseases. We reviewed the literature to delve deeper into the rationale for using vitamin C in treating this type of pathology. There is much evidence in the literature regarding the beneficial effects of vitamin C supplementation for treating autoimmune diseases such as Systemic Lupus

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… Diet and risk of leukemia in the Iowa Women’s Health Study. Cancer Epidemiol. Biomark. Prev. 2002;11:777–781. 69. Rice J.M., Rehm S., Donovan P.J., Perantoni A.O. …

The updated landscape of tumor microenvironment and drug repurposing.

Accumulating evidence shows that cellular and acellular components in tumor microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and response to therapies. Cancer research and treatment have switched from a cancer-centric model to a TME-centric one, considering the increasing significance of TME in cancer biology. Nonetheless, the clinical efficacy of therapeutic strategies targeting TME, especially the specific cells or pathways of TME, remains unsatisfactory. Classifying the chemopathological characteristics of TME and crosstalk among one another can greatly b

Abstracts of the 36th Annual Meeting of the Society of General Internal Medicine. April 24-27, 2013. Denver, Colorado, USA.

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High-Dose Vitamin C for Cancer Therapy.

In recent years, the idea that Vitamin C (Vit-C) could be utilized as a form of anti-cancer therapy has generated many contradictory arguments. Recent insights into the physiological characteristics of Vit-C, its pharmacokinetics, and results from preclinical reports, however, suggest that high-dose Vit-C could be effectively utilized in the management of various tumor types. Studies have shown that the pharmacological action of Vit-C can attack various processes that cancerous cells use for their growth and development. Here, we discuss the anti-cancer functions of Vit-C, but also the potenti

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… The Iowa Women’s Health Study. Am. J. Epidemiol. 1996;144:165–174. doi: 10.1093/oxfordjournals.aje.a008904. 39. Roa F.J., Pena E., Gatica M., Escobar-Acuna K., Saavedra P., Maldonado M., Cuevas M., Moraga-Cid G., Rivas C.I., Munoz-Montesino C. …

Waldenström macroglobulinemia: clinical and immunological aspects, natural history, cell of origin, and emerging mouse models.

Waldenström macroglobulinemia (WM) is a rare and currently incurable neoplasm of IgM-expressing B-lymphocytes that is characterized by the occurrence of a monoclonal IgM (mIgM) paraprotein in blood serum and the infiltration of the hematopoietic bone marrow with malignant lymphoplasmacytic cells. The symptoms of patients with WM can be attributed to the extent and tissue sites of tumor cell infiltration and the magnitude and immunological specificity of the paraprotein. WM presents fascinating clues on neoplastic B-cell development, including the recent discovery of a specific gain-of-function

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… Tompkins, University of Iowa Carver College of Medicine, for reading the manuscript and making valuable suggestions. This work was funded, in part, by research grants 2010-1 from the IWMF and R01CA151354 from the NCI/NIH. …

Резюме докладов 38th - ежегодное собрание общества общей внутренней медицины.

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АКНП 60th Ежегодное совещание: выдержки из плакатов P276 - P550.

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Clinical Posters From JADPRO Live 2025

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Ketogenic Diet in Cancer Prevention and Therapy: Molecular Targets and Therapeutic Opportunities.

Although cancer is still one of the most significant global challenges facing public health, the world still lacks complementary approaches that would significantly enhance the efficacy of standard anticancer therapies. One of the essential strategies during cancer treatment is following a healthy diet program. The ketogenic diet (KD) has recently emerged as a metabolic therapy in cancer treatment, targeting cancer cell metabolism rather than a conventional dietary approach. The ketogenic diet (KD), a high-fat and very-low-carbohydrate with adequate amounts of protein, has shown antitumor effe

2,4 Dinitrophenol as Medicine.

In the sanctity of pure drug discovery, objective reasoning can become clouded when pursuing ideas that appear unorthodox, but are spot on physiologically. To put this into historical perspective, it was an unorthodox idea in the 1950's to suggest that warfarin, a rat poison, could be repositioned into a breakthrough drug in humans to protect against strokes as a blood thinner. Yet it was approved in 1954 as Coumadin® and has been prescribed to billions of patients as a standard of care. Similarly, no one can forget the horrific effects of thalidomide, prescribed or available without a prescri

Unraveling Obesity and Multiple Myeloma: Insights from Epidemiology and Molecular Mechanisms.

Purpose of reviewThe global incidence of obesity has risen dramatically in recent decades, with consequent detrimental health effects. Extensive studies have demonstrated that obesity significantly affects the risk, prognosis, and progression of various cancers, including multiple myeloma (MM). As an established modifiable risk factor for both MM and its precursor stages -monoclonal gammopathy of unknown significance (MGUS) and smoldering MM (SMM)- the association between obesity and disease onset has become a compelling area of research. This review presents a comprehensive overview of the cu

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… female 51.529 male 582 MM | A larger body shape, especially after 60, and extreme weight fluctuation are risk factors for MM | Based on self-reported data for primary exposure variables Number of people with stable weight overestimated Homogeneous populations Blair et al. 2005 [ 56 ] | Cohort study | Iowa …

Электронные постеры

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2026 Приложение к резюме Международного конгресса

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Rapid Fire

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2021 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Las Vegas, Nevada, 31 August–3 September 2021: Video Loops

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Rapid Fire Presentations

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Novel therapeutic approaches for pulmonary fibrosis.

Pulmonary fibrosis represents the end stage of a number of heterogeneous conditions and is, to a greater or lesser degree, the hallmark of the interstitial lung diseases. It is characterized by the excessive deposition of extracellular matrix proteins within the pulmonary interstitium leading to the obliteration of functional alveolar units and in many cases, respiratory failure. While a small number of interstitial lung diseases have known aetiologies, most are idiopathic in nature, and of these, idiopathic pulmonary fibrosis is the most common and carries with it an appalling prognosis - med

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… sildenafil below | Losartan in Treating Patients with IPF (National Cancer Institute, USA) | Open label interventional study; recruiting patients; planned n = 25 | Primary end point: FVC response at 1 year | Results awaited | | Targeting Vascular Reactivity in Idiopathic Pulmonary Fibrosis (University of Iowa …

RESEARCH COMMUNICATIONS OF THE 34th ECVIM-CA CONGRESS.

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