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[Results of congenital cataract surgery using 2,2 microincision in children before the age of 5 years].

BACKGROUND: Thanks to the recent advances of the microsurgical techniques, the results of the congenital cataract surgery in children less t … rected distance visual acuity, evaluated in 12 children, was 5.2/10 ranging from 1/10 to 10/10. The amblyopia was also noted to 12/26 children (46.1 %). Among these children, 11/12 (91.6%) had a delay of surgery and 5/12 (41.6 %) had an unilateral cataract. CONCLUSION: Currently the anatomical prognosis of the congenital cataract surgery in children less t …

Optic neuropathies--importance of spatial distribution of mitochondria as well as function.

Optic neuropathies such as Leber's hereditary optic neuropathy, dominant optic atrophy and toxic amblyopia are an important cause of irreversible visual failure. Although they are associated with a defect of mitochondrial energy production, their pathogenesis is poorly understood. A common feature to all these disorders is relatively selective degeneration of the papillomacular bundle of retinal ganglion cells resulting central or caecocentral visual field defects. The striking similarity in the pattern of clinical involvement seen with these disparate disorders suggests a common pathway in th…

Primary vitrectomy for rhegmatogenous retinal detachment: an analysis of 512 cases.

BACKGROUND: Primary pars plana vitrectomy (PPPV) has gained widespread popularity in the treatment of rhegmatogenous retinal detachments (RR … omical or functional failure included duration of symptoms, low preoperative visual acuity, myopia, amblyopia, hypotony, macular detachment, preoperative PVR, extent of detachment, involvement of inferior quadrants, no detectable breaks, large breaks, breaks posterior to the equator, surgeon, level of surgical training, endocryotherapy, and combined scleral …

["Vision through the hands": experience of a project].

PURPOSE: The Project "Vision through the hands" was performed by the Altino Ventura Foundation, with the purpose of investigating the present child situation with multiple disabilities in the state of Pernambuco, Brazil. METHODS: Birth and social conditions, social problems, and difficulty in accessing the specialized services were evaluated, aiming to collect relevant data with the goal of posterior implantation of a specialized diagnosis and treatment center. Ophthalmologic care and proper treatment were offered. RESULTS: Three hundred and nine children from five reference institutions in

Predictive factors associated with the safety and efficacy of refractive surgery for Myopia: a retrospective cohort study.

BACKGROUND/OBJECTIVES: Wavefront-guided refractive surgery delivers excellent visual outcomes for myopia, but the relative contribution of d … uary 2020 and July 2024. After exclusion of hyperopia, ectatic disorders, incomplete follow-up, and amblyopia (preoperative best-corrected visual acuity [BCVA] logMAR ≥ 0.3), 329 patients (648 eyes) were analyzed. The primary outcomes were the safety index (postoperative BCVA / preoperative BCVA) and the efficacy index (postoperative uncorrected visual acui …

Clinical Performance and Implementation of AI-Enabled Paediatric Ophthalmic Screening, Triage, Diagnosis, and Surveillance in Primary, Community, and Referral-Linked Pathways: A Systematic Review.

Background/Objectives: Artificial intelligence (AI) is increasingly being evaluated for ophthalmic diagnosis, screening, and triage, yet its … d one public dataset descriptor were included, covering retinopathy of prematurity, retinoblastoma, amblyopia risk, myopia, congenital cataract, and visual-acuity assessment. AI systems frequently demonstrated promising diagnostic or screening performance, including sensitivity-first detection of treatment-requiring retinopathy of prematurity, high discrimi …

Parents' perception of common childhood eye diseases: a community-based cross-sectional study.

BACKGROUND: Childhood eye diseases can significantly affect vision. This may have a negative impact on mental development, academic performa … e of 7 years supports normal visual development, and 167 (62.5%) recognised that early treatment of amblyopia leads to better outcomes. Gaps were also identified among the study population, as 92 (34.5%) correctly defined cataract and 126 (47.2%) believed that occasional eye deviation in young children is normal. As per the participating parents' practice, …

Prevalence of visual impairment and refractive error-related risk factors in preschool children in beijing, China.

BACKGROUND: Childhood vision loss represents a significant public health burden worldwide, with the majority of these cases being treatable … luding astigmatism (24.2%), hyperopia (19.6%), myopia (9.1%), and anisometropia (6.4%), followed by amblyopia (9.8%) and strabismus (2.3%). Factors associated with VI, as determined through both univariate and multivariate analyses, included older age (OR = 1.472, P < 0.01), greater absolute value of cylinder (OR = 5.691, P < 0.01), myopia (OR = 85.432, P < …

Social Media Interventions and Postoperative Follow-Up in Congenital Ectopia Lentis: A Randomized Clinical Trial.

IMPORTANCE: Congenital ectopia lentis (CEL), often associated with systemic diseases such as Marfan syndrome, requires rigorous postoperativ … ter improvements in parental CEL knowledge accuracy (10.6%, 95% CI, 7.8%-13.5%) and higher rates of amblyopia treatments (RR, 2.40; 95% CI, 1.26-4.56). CONCLUSIONS AND RELEVANCE: Results of this randomized clinical trial reveal that social media smartphone application-based interventions significantly improved follow-up adherence and increased parental kno …

[Clinical and laboratory characteristics and genetic diagnosis of Kabuki syndrome].

Objective: To investigate the clinical features, laboratory characteristics and genetic diagnosis of Kabuki syndrome (KS). Methods: Between … ; two cases presented with strabismus and earlap malformation respectively; one case presented with amblyopia. Six cases presented with skeletal anomalies. Six cases presented with dermatoglyphic anomalies. All cases presented with mild to moderate mental retardation. Three cases presented with short stature. Four cases presented with cardiac abnormalities. …

Adjustable surgical treatment of adult exotropia: postoperative target angles and surgical success.

OBJECTIVES: This study had 3 objectives: (i) to characterize clinical profiles of adults with consecutive exotropia (CXT), intermittent exot … ly. RESULTS: Comparison of clinical profile groups showed that CXT patients had more hyperopia and amblyopia and smaller preoperative deviations; IXT patients had more diplopia and larger preoperative deviations (near > distance); and SXT patients had poor vision in the deviating eye and larger preoperative deviations. Immediate postoperative alignment was …

Retinopathy of prematurity in infants weighing less than 500 grams at birth enrolled in the early treatment for retinopathy of prematurity study.

PURPOSE: To describe patient characteristics, classification, and onset of prethreshold retinopathy of prematurity (ROP), and ocular finding … es in 4 (14.8%), and an unfavorable structural outcome (stage 4B) in 1 (3.7%). One infant developed amblyopia, 4 infants developed nystagmus, 4 infants developed strabismus, and 8 infants developed myopia >-5.00 diopters. CONCLUSIONS: This is the first report on characteristics of prethreshold ROP in infants with birth weights <500 g. These infants are at …

Penetrating keratoplasty for endothelial decompensation in eyes with buphthalmos.

PURPOSE: To evaluate the prognosis and complications of penetrating keratoplasty (PKP) for corneal decompensation in eyes with buphthalmos a … ficantly improved but is usually still very limited by advanced glaucomatous optic nerve damage and amblyopia. Efficient control of IOP before and after PKP is mandatory in eyes with buphthalmos to avoid graft failure and progress of glaucomatous optic nerve atrophy.

Ocular Signs and Ocular Comorbidities in Monoclonal Gammopathy: Analysis of 80 Subjects.

PURPOSE: To examine the ocular signs of monoclonal gammopathy and to evaluate ocular comorbidities in subjects with monoclonal gammopathy. Patients and Methods. We analyzed patients from two large referral hematology centers in Budapest, diagnosed and/or treated with monoclonal gammopathy between 1997 and 2020. As a control group, randomly selected individuals of the same age group, without hematological disease, have been included. There were 160 eyes of 80 patients (38.75% males; age 67.61 ± 10.48 (range: 38-85) years) with monoclonal gammopathy and 86 eyes of 43 control subjects (32.56% mal

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… chronic blepharitis in 16 (10.00%), glaucoma in 12 (7.50%), age-related macular degeneration in 12 (7.50%), epiretinal membrane in 10 (6.25%), Fuchs dystrophy in 8 (5.00%), peripheral retinal degeneration in 7 (4.38%), corneal immunoglobulin deposition in 6 (3.75%), diabetic retinopathy in 4 (2.50%), amblyopia … previous cataract surgery in 12 (13.95%), Meibomian gland dysfunction in 10 (11.63%), glaucoma in 4 (4.65%), diabetic retinopathy in 4 (4.65%), peripheral retinal degeneration in 4 (4.65%), posterior cortical cataract in 3 (3.49%), Fuchs dystrophy in 2 (2.33%), epiretinal membrane in 2 (2.33%), and amblyopia …

Electroacupuncture improves V1 cortex synaptic plasticity via the CREB/BDNF/TrkB pathway in juvenile rats with monocular deprivation.

The present study aims to investigate the impact of the CREB/BDNF/TrkB signaling pathway on synaptic plasticity in the visual cortex of juvenile amblyopic rats that have undergone monocular deprivation (MD). This study involved sixty 2-week-old Sprague-Dawley (SD) juvenile rats, which were not specified by gender. In the first part of the study, 24 rats were randomized into control and MD groups; In the second part, 36 rats were randomized into MD, electroacupuncture (EA) and EA + CREB antagonist (666-15) groups. The MD model was established using the monocular suture method. 14 d after monocu

HOTV Vision Test Compared With Tumbling E for Pediatric Vision Screening.

IMPORTANCE: Accurate assessment of uncorrected visual acuity (UCVA) is fundamental to pediatric vision screening. Although the HOTV letter-m … VA (logMAR). Secondary outcomes included referral rates for reduced UCVA, screening performance for amblyopia and refractive errors, testability, and time required for vision test. RESULTS: Overall, mean (SD) UCVA was 0.15 (0.22) (20/25) with HOTV and 0.20 (0.20) (20/32) with tumbling E (95% CI, -0.07 to -0.02; P < .001). The difference between the 2 tests …