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A systematic review and meta-analysis of herpes zoster risk in adults with immunocompromised conditions and autoimmune diseases in Asia-Pacific.

Asia-Pacific (APAC) faces an increasing burden of herpes zoster (HZ) over time. The risk of HZ and its complications are increased in immunocompromised (IC) patients and those with autoimmune diseases (AID). Our study aimed to synthesize evidence on the epidemiological burden of HZ and its complications among the general adult population and patients with IC/AID conditions in APAC. Following a systematic literature review, we performed meta-analyses for outcomes where ≥3 studies met the inclusion criteria. Of the 271 articles identified, 75 were included for meta-analysis. We found a high burd

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… The full methodologic details of the SLR (including the search terms and full list of outcomes of interest) have been described in Chen et al. 2024. 4 For the current meta-analysis, the literature search was extended to five Southeast Asian countries (Indonesia, Malaysia, the Philippines, Thailand, and … Briefly, the inclusion criteria were: 1) studies published in the English language, 2) studies providing HZ data for adults ≥18 years, 3) studies conducted in Australia, China, Hong Kong, Indonesia, Japan, Korea, Malaysia, New Zealand, the Philippines, Singapore, Taiwan, Thailand, and Vietnam, and 4) …

Incentives for smoking cessation.

BACKGROUND: Financial incentives (money, vouchers, or self-deposits) can be used to positively reinforce smoking cessation. They may be used … tudies at unclear risk. Thirty-three of the trials were run in the USA, two in Thailand, one in the Philippines, one in Hong Kong, and one in South Africa. The rest were European. Incentives offered included cash payments, self-deposits, or vouchers for goods and groceries, offered directly or collected and redeemable online. The pooled RR for quitting with i …

Стратегии охраны мозга у лиц среднего возраста с незначительным нейрокогнитивным расстройством: аналитическая оценка.

Здравоохранение мозга означает оптимальное функционирование и целостность мозга, определяемые сложными когнитивными, психологическими и социальными детерминантами. Лица с легким нейрокогнитивным расстройством (mNCD) подвергаются повышенному риску развития слабоумия. Первостепенное состояние мозга имеет важное значение на протяжении всей жизни, особенно в период среднего возраста, когда риск для здоровья часто возникает наряду с тяжелыми жизненными обязанностями. В международных рамочных программах особое внимание уделяется изменению факторов риска на протяжении всей жизни в целях снижения риск

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… Not discussed | Not discussed | 79% male; 29% female | Not reported | 10 high school graduates & 4 had some college | Not reported | living in an assisted living facility- existing social structure that can provide day-to-day support | Age & brain injury as a disability status included Parial et al., Philippines … | Bulacan province, Philippines | Not reported | Not reported | 76.7% female; 23.3% male | Not reported | 28.3% elementary, 53.3% secondary, 18.3% college | Not reported | 70% married, 3.3% single, 6.7% separated/ divorced, 20% widowed | Age & health status included Pettigrew et al., USA | USA (John …

Fortification of rice with vitamins and minerals for addressing micronutrient malnutrition.

BACKGROUND: Rice fortification with vitamins and minerals has the potential to increase the nutrition in rice-consuming countries where micr … a control (8245 participants). Four studies were conducted in India, three in Thailand, two in the Philippines, two in Brazil, one each in Bangladesh, Burundi, Cambodia, Indonesia, Mexico and the USA. Two studies involved non-pregnant, non-lactating women and 10 involved pre-school or school-age children. All 17 studies reported fortification with iron. Of t …

Imaging in plasma cell disorders-consensus recommendations of the Asian myeloma network bone imaging workgroup.

The role of imaging in accurate classification and management of plasma cell disorders is substantial with the increasing evidence in the ability of cross-sectional imaging to identify disease related manifestations. International myeloma working group and nation-wide guidelines provide recommendations for guiding practice. However, there are remarkable variations in practice globally and in particular, adoption of incorrect imaging techniques due to lack of awareness/education, lack of equipment or personnel and resource constraints. These limitations are not specific to any particular geogra

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… Asian Myeloma Network (AMN) was established by the international myeloma foundation and is comprised of myeloma experts from China, Hong Kong, Malaysia, Taiwan, Japan, Philippines, Singapore, South Korea, Vietnam, and Thailand. … The participants spanned countries and regions across Asia including China, Japan, South Korea, Malaysia, Taiwan, Thailand, Philippines, Vietnam, and Singapore from public and private hospitals in tertiary as well as peripheral or district setting [ Figure S1 ] and were all Haematologists with an interest …

Evaluation of Neurosurgery Consultations in Hospitalized Geriatric Patients During and After the COVID-19 Pandemic.

Background and Objectives: This study aims to evaluate neurosurgery consultations for elderly patients during and following the COVID-19 pandemic. Materials and Methods: This study included patients aged 65 and older who were hospitalized in non-neurosurgery departments at Istinye University Gaziosmanpasa Medical Park Hospital and were referred for neurosurgery consultations between 1 April 2020 and 31 May 2024. Patients in the intensive care unit and emergency department were excluded. The period from 1 April 2020 to 30 April 2022 was defined as the pandemic period, and from 1 May 2022 to 31

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… Neurosurgery in the elderly: Findings from a cohort in the Philippines J. Clin. Neurosci. 2024 128 110794 10.1016/j.jocn.2024.110794 39146578 7. Koester S.W. Catapano J.S. Ma K.L. Kimata A.R. Abbatematteo J.M. Walker C.T. Cole T.S. Whiting A.C. Ponce F.A. Lawton M.T. …

Topical antibiotics for treating bacterial keratitis: a network meta-analysis.

BACKGROUND: Infectious keratitis, commonly known as corneal infection, is a major cause of blindness, affecting approximately six million pe … diagnosed with BK. The studies were conducted in Australia, Canada, India, Iran, Israel, Japan, the Philippines, Serbia, Thailand, the UK, and the USA. The majority of participants were of working age, with a mean age ranging from 26 to 66 years, and 58% were male. We classified six types of interventions: fluoroquinolone monotherapy, cephalosporin monotherap …

Interventions for pityriasis rosea.

BACKGROUND: Pityriasis rosea is a scaly, itchy rash that mainly affects young adults and lasts for 2 to 12 weeks. The effects of many availa … included studies did not categorise. Six studies were conducted in India, three in Iran, two in the Philippines, and one each in Pakistan, the USA, and China. The included studies were conducted in dermatology departments and a paediatric clinic. Study duration ranged from 5 to 26 months. Three studies were funded by drug manufacturers; most studies did not r …

Donor Evaluation for Hematopoietic Stem and Progenitor Cell Collection

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… Caicos Islands U.S Virgin Islands Venezuela Oceana/Pacific Islands Africa American Samoa Fiji Kosrae, Federated States of Micronesia Marshall Islands New Caledonia Palau Papua New Guinea Samoa Solomon Islands Tonga Asia Bangladesh Burma (Myanmar) Cambodia India Indonesia Laos Malaysia Maldives Pakistan Philippines … Islands U.S Virgin Islands Venezuela Oceana/Pacific Islands | Africa | American Samoa Fiji Kosrae, Federated States of Micronesia Marshall Islands New Caledonia Palau Papua New Guinea Samoa Solomon Islands Tonga Asia Bangladesh Burma (Myanmar) Cambodia India Indonesia Laos Malaysia Maldives Pakistan Philippines …

The Mediating Role of Mental Adjustment in the Relationship between Perceived Stress and Depressive Symptoms in Hematological Cancer Patients: A Cross-Sectional Study.

BackgroundDepression is a particularly common psychological disorder that affects cancer patients. Diagnosed with hematological malignancies constitute a serious unpredictable and uncontrollable medical stress situation and patients are susceptible to suffer from depressive symptoms. The aims of the study were to explore the correlation between perceived stress and depressive symptoms in patients with hematological malignancies, and assess the mediating role of mental adjustment between these variables.MethodsA single center, cross-sectional study was performed by convenience sampling between

Reduced-versus Standard-dose Melphalan as Single-agent Conditioning Regimen in Auto HSCT for Multiple Myeloma: A Systematic Review and Meta-Analysis.

BackgroundThe optimal conditioning dose of melphalan for autologous hematopoietic stem cell transplantation (AHSCT) in multiple myeloma remains a subject of debate. While prior studies have presented conflicting evidence on whether standard-dose melphalan (SDM, 200 mg/m2) provides a statistically significant survival advantage over reduced-dose melphalan (RDM, 140 mg/m2), further investigation is necessary to clarify this.AimThis systematic review and meta-analysis aimed to consolidate existing studies and assess whether standard-dose melphalan confers a significant benefit in terms of overall

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… An exception for review by the University of the Philippines Manila Research Ethics Board (UPMREB) was also applied and granted based on the criteria for exemption in the National Ethical Guidelines for Research Involving Human Participants 2022 (provision 47, page 48), that is, “protocols that neither …

Treatment Decision Making at Diagnosis for Children Presenting With Advanced Cancer in Low- and Middle-Income Countries.

PurposeAlthough most children diagnosed with cancer live in low- and middle-income countries (LMICs), research exploring decision making in these settings remains sparse. When children present with advanced cancer in LMICs, local centers may lack resources to provide treatment required to achieve cure. Existing treatment guidelines often do not account for contextual and resource variations influencing decision making. This qualitative study sought to understand physician approaches to treatment decision making for children presenting with advanced cancer at diagnosis in LMICs.MethodsSemistruc

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… Dolendo, MD, FPPS, FPSPO (Southern Philippines Medical Center, Children's Cancer Institute, Davao City, Philippines); Diego Figueredo, MD (Hospital de Clinicas, National University of Asunción, Asuncion, Paraguay); Lisa M. …

Keyword Index for Volume 100

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… perioperative metastatic tumour growth 1589 peripheral blood 153, 1937 peritoneal dissemination 1937 persistence 1184 persistent trophoblastic disease 979 PET CT 693 Petersen Index 701 pH 1287 pharmacogenetics 732, 1549 pharmacogenomics 870 pharmacokinetics 1549 Phase-I trial 315, 1373 Philippines …

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015. METHODS: We estimated incid

Medical countermeasures against henipaviruses: a review and public health perspective.

Henipaviruses, including Nipah virus, are regarded as pathogens of notable epidemic potential because of their high pathogenicity and the paucity of specific medical countermeasures to control infections in humans. We review the evidence of medical countermeasures against henipaviruses and project their cost in a post-COVID-19 era. Given the sporadic and unpredictable nature of henipavirus outbreaks, innovative strategies will be needed to circumvent the infeasibility of traditional phase 3 clinical trial regulatory pathways. Stronger partnerships with scientific institutions and regulatory au

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… prominent respiratory symptoms (eg, atypical pneumonia and severe respiratory problems, including acute respiratory distress) and human-to-human transmission. 4 Since 1994, henipavirus spillover events have caused human outbreaks in several countries, including Australia, Bangladesh, India, Malaysia, the Philippines … Four countries (Bangladesh, India, Malaysia, and the Philippines) historically affected by henipaviruses are low-income or middle-income countries 145 whereas two (Australia and Singapore) are high-income countries. …

Mortality Trend of Hematological Neoplasms in Babol, Northern Iran (2013-2021).

BackgroundBlood cancers account for a significant proportion of cancer-related deaths worldwide. In this study, hematological cancer mortality in northern Iran was examined during 2013-2021, along with age-adjusted mortality rates.MethodsIn a cross-sectional study, we conducted an analysis of all deaths from hematological neoplasms registered in Babol city between 2013 and 2021. In order to estimate the population, the most recent census data was used. The mortality rates and trends for each hematological malignancy were reported in crude mortality rate (CMR) and age-standardized mortality rat

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… According to estimates from one study, the mortality trend for leukemia for both genders from 1980 to 2017 has decreased in most countries while it has increased in four countries, including the Philippines, Ecuador, Belarus, and Thailand. 25 Another study using the Global Burden of Disease (GBD) data …

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate how disease burden changes with development. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 20

Standard Poster Abstracts for the 17th Asia Pacific Heart Rhythm Society (APHRS) Scientific Sessions

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… Pacing, University of the Philippines, Philippine General Hospital, Manila, Philippines, 8 Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital ‐ Division of Cardiology, Department of Medicine, Tri‐Service General Hospital, Taipei, Taiwan, 9 Heart Rhythm … INDUCED VENTRICULAR TACHYCARDIA IN ACUTE RHEUMATIC FEVER COMPLICATED WITH NON‐ISCHEMIC CARDIOMYOPATHY TAM ADRIAN AYA‐AY , GISELLE GERVACIO, MICHAEL‐JOSEPH AGBAYANI, WILFRED DEE, BIANCA VELANDO, ZANE OLIVER NELSON University of the Philippines‐Philippine General Hospital, Manila City, Philippines Introduction …

Ассоциации физического партнерского насилия и пережитого сексуального насилия с рисковыми поведениями и психическим здоровьем среди студентов университетов из 25 стран.

ИСТОРИЯ ВОПРОСА: Исследование было направлено на изучение связей между виктимизацией физического партнера и/или сексуальным насилием и различными видами поведения, сопряженными с риском для здоровья, и психическим здоровьем студентов университетов 25 странами. МЕТОДЫ: С использованием плана перекрестного исследования, 18,335 Студенты высших учебных заведений среднего возраста 20 лет с 25 страны Африки, Северной и Южной Америки и Азии ответили на сообщения о случаях насилия в отношениях между людьми, действиях, подрывающих здоровье, мерах по охране психического здоровья и защитных факторах.РЕЗУ

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… Methods Sample and procedure The cross-sectional study comprised 18,335 college or university students with a median age of 20 years (interquartile range = 3 years) with complete physical IPV and/or sexual violence victimization data from 25 countries in Southeast Asia: Indonesia, Laos, Philippines …

Active Mycobacterium tuberculosis infection at a comprehensive cancer center, 2006-2014.

BackgroundMorbidity and mortality from Mycobacterium tuberculosis (Mtb) infection remain significant in cancer patients. We evaluated clinical characteristics, management, and outcomes in patients with active Mtb infection at our institution who had cancer or suspicion of cancer.MethodsWe retrospectively examined medical records of all patients with laboratory-confirmed active Mtb infection diagnosed between 2006 and 2014.ResultsA total of 52 patients with laboratory-confirmed active Mtb infection were identified during the study period, resulting in an average rate of 6 new cases per year. Th

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… A total of 31 patients (60%) were foreign-born, with 29 (56%) originating from countries with a high burden of tuberculosis [14 (70%) without cancer and 15 (47%) with cancer], including the Philippines (9), India (5), China (4), Vietnam (2), Pakistan (2), and Thailand (1). …