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Diagnostic, Clinical and Post-SARS-CoV-2 Scenarios in Cancer Patients with SARS-CoV-2: Retrospective Analysis in Three German Cancer Centers.

Oncologists face challenges in the management of SARS-CoV-2 infections and post-SARS-CoV-2 cancer treatment. We analyzed diagnostic, clinical and post-SARS-CoV-2 scenarios in patients from three German cancer centers with RT-PCR confirmed SARS-CoV-2 infection. Sixty-three patients with SARS-CoV-2 and hematologic or solid neoplasms were included. Thirty patients were initially asymptomatic, 10 of whom developed COVID-19 symptoms subsequently. Altogether 20 (32%) patients were asymptomatic, 18 (29%) had mild, 12 (19%) severe and 13 (20%) critical courses. Lymphocytopenia increased risk of severe

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… combined with radiotherapy | 1 | 2% Immunotherapy | 7 | 11% - immunotherapy monoregimen | 5 | 8% - combined with radiotherapy | 2 | 3% Targeted therapy | 4 | 6% Surgery | 4 | 6% Hormonal therapy | 1 | 2% Radiotherapy | 1 | 2% No therapy yet due to first diagnosis or “watch and wait” strategy | 2 | 3% Aftercare …

Research in haematological cancers: What do patients in the Netherlands prioritise?

IntroductionThe experiential knowledge of patients can provide research communities with complementary perspectives on disease. The aim of this study was to identify and prioritise everyday problems and research needs of haematological cancer patients and people who have undergone a stem cell transplantation.MethodsA mixed-method participatory research approach (the Dialogue Model) was applied, including interviews (n = 19), four focus group discussions (n = 27), a questionnaire (n = 146) and a stakeholder dialogue meeting (n = 30) with patients in the Netherlands.ResultsPatients' physical dis

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… (P2, FGD Cured, late side effects) Participants to FGDs advocate research into the effects of standardisation of aftercare. Also, they would like to improve the efficacy of these check‐ups and be provided with information regarding the late side effects of treatments. …

Bridging the gap - Establishing a dental-oncology service in a cancer centre.

Dental disease remains the most common non-communicable disease worldwide. It predisposes patients to significant morbidities following bone modifying agents or radiation therapy to the head and neck. Preventative dental regimes effectively reduce the risk of both medication-related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis (ORN) in these patients. Co-ordination of routine dental care as a component of mainstream oncology treatment optimises long term outcomes for oncology patients. This case series offers insights into patient, institutional and social difficulties that challeng

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… As a result of post-operative infection, her treatment plan also included 3 months of intense aftercare and wound debridement following decoronation of the wisdom tooth. …

Устойчивые выгоды мультидоменального стиля жизни при множественном склерозе в исследовании LIMS: A 24-Month Продолжайте.

СПРАВОЧНАЯ ИНФОРМАЦИЯ И ЦЕЛИ: Множественный склероз (МС) часто приводит к физическим, когнитивным и психологическим расстройствам, существенно влияющим на повседневное функционирование и качество жизни. Поскольку нынешняя медикаментозная медикаментозная терапия не в полной мере предотвращает прогресс в развитии заболеваний, интерес к потенциальной роли изменяемых факторов образа жизни растет. Мы провели оценку.1) сохранялось ли воздействие на результаты, представляемые пациентами 24 месяцев и2) долгосрочные изменения в образе жизни после завершения программы MS.МЕТОДЫ: УЧАСТНИКИ СООБЩЕНИЙ 3-mo

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… In conclusion, the multimodal digital LIMS program resulted in modest improvements immediately after the intervention, with partial attenuation during a 21-month aftercare period; however, outcomes generally remained improved relative to baseline, and the absence of deterioration over 21 months may in …

Measurement Properties of Patient-Reported Outcome Measures for Adolescent and Young Adult Survivors of a Central Nervous System Tumor: A Systematic Review.

Purpose: To identify and evaluate patient-reported outcome measures (PROMs) for assessing survivorship-related concepts for adolescent and young adult (AYA) survivors of central nervous system (CNS) tumors. Methods: We searched five electronic databases. Two researchers independently screened all titles for inclusion and used consensus-based standards for the selection of health measurement instruments (COSMIN) guidance to grade the quality of evidence for each measurement property. Results: Four studies met eligibility criteria: single-item pain thermometer; single-item fatigue thermometer; 3

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… Enhanced quality and productivity of long- term aftercare of cancer in young people. Arch Dis Child 2013;98(10):818–824. 14. NHS England. The NHS Long Term Plan. 2019. Available from: https://longermplan.nhs.uk/publication/nhs-long-term-plan/ [Last accessed: January 12, 2022]. 15. …

Systematic Review of Intravenous Ascorbate in Cancer Clinical Trials.

BackgroundAscorbate (vitamin C) has been evaluated as a potential treatment for cancer as an independent agent and in combination with standard chemotherapies. This review assesses the evidence for safety and clinical effectiveness of intravenous (IV) ascorbate in treating various types of cancer.MethodsSingle arm and randomized Phase I/II trials were included in this review. The PubMed, MEDLINE, and Cochrane databases were searched. Results were screened by three of the authors (GN, RP, and CJP) to determine if they met inclusion criteria, and then summarized using a narrative approach.Result

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… Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare: Results of a retrospective, multicentre, epidemiological cohort study in Germany In Vivo 2011 25 983 990 22021693 69. Riordan H.D. Hunninghake R.B. Riordan N.H. …

Интернет-упражнения и содействие физической активности лиц с множественным склерозом: выборочное контролируемое испытание.

Мы провели оценку воздействия 12-недельной программы поощрения физической активности на основе Интернета для лиц с множественным склерозом. Мы провели многоцентральное, случайное исследование, контролируемое списками ожидания. Группа по оказанию помощи (ГГ) получила 12-недельную программу, за которой последовало 12 недель с обычной заботой. Контрольная группа (КГ) получала только обычную медицинскую помощь. Основными компонентами 12-недельной программы были: 1) специальная программа занятий на дому, 2) средства электронного обучения, 3) телефонные и видеозаписи с терапевтом, 4) предоставление

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… These interventions were either 6-month behavioral interventions based on social cognitive theory [ 19 , 56 , 68 ] or 12-week rehabilitation aftercare programs for pwMS suffering from fatigue [ 69 ]. …

Management of keratinocyte carcinoma - Special considerations in the elderly.

Keratinocyte carcinomas (KCs) are now an epidemic in The United States of America, especially in elderly patients. KCs, including basal cell carcinoma and squamous cell carcinoma, can lead to disfigurement and occasionally death. However, the lower mortality rate associated with KC compared with melanoma allows for increased flexibility in the selection of treatment. Flexibility in treatment is particularly important in the elderly given that this patient population often has medical comorbidities that should be considered. These patients may have multiple KCs, higher risk tolerance to recurre

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… The advantages of RT include noninvasive, quick, and painless treatment sessions and minimal aftercare. RT may be particularly useful for patients who are frail, on multiple anticoagulants, have poor wound healing capacity, or cannot properly perform wound care ( Bhatnagar et al., 2016 ). …

International guidelines for groin hernia management.

INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indica … hnique) can be offered. Day surgery is recommended for the majority of groin hernia repair provided aftercare is organized. Surgeons should be aware of the intrinsic characteristics of the meshes they use. Use of so-called low-weight mesh may have slight short-term benefits like reduced postoperative pain and shorter convalescence, but are not associated wi …

Воздействие систем телемониторинга на лечение раковых заболеваний: систематический обзор.

В рамках этого систематического обзора оценивается воздействие, пригодность для использования, техническая эффективность и применение систем телемониторинга при лечении рака у взрослых. Этот систематический обзор проводился в соответствии с предпочтительными принципами отчетности для системных обзоров и мета-анализов и коллегиального обзора стратегий электронного поиска. Пубмед, МЕДЛИНА и КИНАХЛ были обысканы с июня 2013 по март 2025. Термины " поиск " охватывают лечение раковых заболеваний, системы телемониторинга, мобильное медицинское обслуживание (медицинское здоровье), электронн

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… . | Pts with BC/survivors in therapy or aftercare; n=60 (I=38; C=22). | PHQ-9, EORTC QLQ-C30 fatigue, IPAQ (MET-min) | In the IC, PHQ-9 scores ↓ by 2.5 points (~32.9% reduction; p<0.01; d=0.8) and fatigue scores ↓ by 9.9 points (~19.5% reduction; p<0.01), with ↑ physical activity, particularly among …

Adaptation of the Charlson Comorbidity Index for Register-Based Research in Sweden.

PurposeComorbidity indices are often used to measure comorbidities in register-based research. We aimed to adapt the Charlson comorbidity index (CCI) to a Swedish setting.MethodsFour versions of the CCI were compared and evaluated by disease-specific experts.ResultsWe created a cohesive coding system for CCI to 1) harmonize the content between different international classification of disease codes (ICD-7,8,9,10), 2) delete incorrect codes, 3) enhance the distinction between mild, moderate or severe disease (and between diabetes with and without end-organ damage), 4) minimize duplication of co

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… Kronisk njursvikt, chronic kidney failure) 586 (Icke specificerad njursvikt, unspecified kidney failure) 588A (Renal osteodystrofi, Renal osteodystrophy) V42A (Njurtransplantation, kidney transplantation) V45B (Behov av återkommande njurdialys, Kidney dialysis) V56 (Eftervård med återkommande dialys, Aftercare …

Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome.

The recent outbreak of Covid19 has required urgent treatments for numerous patients. No suitable vaccines or antivirals are available for Covid19. The efficiency against Covid19 of WHO therapies of choice, that are two antivirals developed for other pathologies, is controversial. Therefore, alternative approaches are required. Intravenous (IV) Vitamin C (Vit-C) has emerged as one of the other alternatives for this purpose. Here we review the effects of IV Vit-C on the immune system response, the antiviral properties of IV Vit-C, and finally the antioxidant properties of IV Vit-C to specificall

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… Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare: results of a retrospective, multicentre, epidemiological cohort study in Germany. In Vivo. 2011;25(6):983–990. 63. Yeom C.H., Jung G.C., Song K.J. …

Technological Resources for Physical Rehabilitation in Cancer Patients Undergoing Chemotherapy: A Scoping Review.

Background/Objectives: Cancer patients undergoing chemotherapy often face challenges that reduce their physical function and quality of life. Technological resources offer innovative solutions for physical rehabilitation, but the extent of their application in this context remains unclear. This scoping review aims to explore and map the various technological tools used to support physical rehabilitation in cancer patients during chemotherapy, focusing on their potential to improve outcomes and enhance patient care. Methods: A scoping review was conducted following the Joanna Briggs Institute (

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… S16 [ 45 ] | mHealth app (Smart Aftercare app) | DHI 1.2—Client-targeted (self-monitoring) | Physical activity, intensity tracking | High adherence, feasible for remote monitoring of exercise capacity | Easy to use for tracking physical activity intensity and providing real-time feedback for patients …

Ferroptosis, lipid metabolism, and genetic regulation in postoperative rehabilitation of elderly hip fractures: from molecular mechanisms to clinical translation.

BACKGROUND: Elderly hip fracture represents a major global public health challenge, with postoperative rehabilitation involving complex molecular mechanisms and metabolic networks. Beyond osteoporotic fractures, pathological hip fractures caused by tumor bone metastasis constitute a non-negligible proportion in elderly patients, with molecular pathological mechanisms significantly different from osteoporotic fractures. Recent research has confirmed that ferroptosis (iron-dependent regulated cell death) and lipid metabolism dysregulation are key links in fracture healing and functional recovery

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… Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database Syst. Rev. 11 (11), CD001880. 10.1002/14651858.CD001880.pub6 Ayala A., Muñoz M. F., Argüelles S. (2014). …

Effect of healthcare professional-delivered health literacy interventions on patient reported outcomes in cancer patients - a systematic review.

BACKGROUND: Cancer impairs quality of life (QoL) and mental wellbeing and other patient-reported outcomes (PROs). Health literacy (HL) in cancer patients can be an intermediary factor and can improve PROs. For this reason, the aim of this systematic review is to identify HL interventions delivered by healthcare professionals (HCPs) that have an impact on PROs. METHODS: We carried out a comprehensive literature search on 1 December 2023 across nine databases and included studies 1) with HL interventions delivered through HCPs aiming to have an effect on HL, HL-related outcomes, anxiety, depress

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… After placement, patients received education cards and brochures about aftercare. HCPs used checklists to supervise each patient and their families. After this intervention, the compliance in the intervention group was significantly higher than in the control group [ 63 ]. …

Diverse antitumor effects of ascorbic acid on cancer cells and the tumor microenvironment.

Ascorbic acid has attracted substantial attention for its potential antitumor effects by acting as an antioxidant in vivo and as a cofactor in diverse enzymatic reactions. However, solid proof of its clinical efficacy against cancer and the mechanism behind its effect have not been established. Moreover, cancer forms cancer-specific microenvironments and interacts with various cells, such as cancer-associated fibroblasts (CAFs), to maintain cancer growth and progression; however, the effect of ascorbic acid on the cancer microenvironment is unclear. This review discusses the effects and mechan

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… Intravenous vitamin c administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare: results of a retrospective, multicentre, epidemiological cohort study in Germany . In Vivo ( 2011 ) 25 : 983–90 . 22021693 162 Takahashi H Mizuno H Yanagisawa A . …

An Individualized Exercise Intervention for People with Multiple Myeloma-Study Protocol of a Randomized Waitlist-Controlled Trial.

People with multiple myeloma (MM) are second only to people with lung cancer for the poorest reported health-related quality of life (HRQoL) of all cancer types. Whether exercise can improve HRQoL in MM, where bone pain and lesions are common, requires investigation. This trial aims to evaluate the efficacy of an exercise intervention compared with control on HRQoL in people with MM. Following baseline testing, people with MM (n = 60) will be randomized to an exercise (EX) or waitlist control (WT) group. EX will complete 12-weeks of supervised (24 sessions) and unsupervised (12 sessions) indiv

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… High-intensity interval training in the therapy and aftercare of cancer patients: A systematic review with meta-analysis. J. Cancer Surviv. 2019;13:205–223. doi: 10.1007/s11764-019-00743-3. 19. Viana R.B., Naves J.P.A., Coswig V.S., de Lira C.A.B., Steele J., Fisher J.P., Gentil P. …

The Power of Movement: How Exercise Influences Chemotherapy-Induced Peripheral Neuropathy.

As the number of cancer patients and survivors increases, we face a rising challenge: the long-term impact of the adverse effects of cancer treatment. One of the known adverse effects is chemotherapy-induced peripheral neuropathy (CIPN), which courses with pain complaints. The treatments of CIPN have reduced efficacy. The neurobiological causes of CIPN have been mainly ascribed to peripheral nerve damage, but recent studies show effects in the brain, namely in the descending pain modulatory systems. Physical exercise seems to be associated with better outcomes in CIPN patients, but the mechani

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… Physical Activity, Exercise and Breast Cancer—What Is the Evidence for Rehabilitation, Aftercare, and Survival? A Review. Breast Care. 2018;13:93–101. doi: 10.1159/000488717. 82. Tajerian M., Clark J.D. Nonpharmacological Interventions in Targeting Pain-Related Brain Plasticity. …

mHealth technologies in research studying cardiovascular health in cancer: A systematic review.

Cancer survivors face an increased risk of cardiovascular disease (CVD) due to treatment-related toxicity, lifestyle factors, and comorbidities. Addressing CV health is crucial for improving quality of life and long-term outcomes. The American Heart Association's Life's Essential 8 framework highlights modifiable determinants of CV health, emphasizing early detection and monitoring. Mobile health (mHealth) technologies, such as wearables and smartphone apps, offer continuous tracking, yet their applications in cancer survivorship remain unclear. This review systematically characterizes the typ

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… mHealth care using a rehabilitation program for colorectal cancer patients | • Sample size : 102 • Study duration : 12 weeks • Study type : prospective, non-randomized • Cancer site : colorectal (stages NS) | Risk factors • PA Surrogate endpoints • Signs and symptoms of CV risk • HR | • Mobile app ( “Aftercare …

Factors influencing cancer patients' experiences of care in the USA, United Kingdom, and Canada: A systematic review.

The extent to which individual and structural factors influence cancer patients' reports of their experiences are not yet well understood. We sought to identify which groups of patients consistently report poorer experiences and whether structural care factors might also be associated with better or worse reports. We conducted a systematic review of literature in PubMed and Web of Science with the date of last search as 27th of February 2022 following PRISMA guidelines. We focused on studies from three established population-based surveys datasets and instruments. After screening 303 reference

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… Positive experiences were attributed to the caring and professional nature of cancer staff, but some specific concerns about aftercare and perceived disconnect between primary and secondary care. …