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A malignant omental extra-gastrointestinal stromal tumor on a young man: a case report and review of the literature.

BACKGROUND: Gastrointestinal stromal tumors (GIST) are uncommon intra-abdominal tumors. These tumors tend to present with higher frequency i … ized tomography imaging demonstrated an intra-abdominal mass of 22 cm, without invasion of adjacent viscera or liver lesions. This mass was resected en bloc with its fused omentum and an adherent portion of sigmoid colon. Pathology results demonstrated a malignant gastrointestinal stromal tumor with positive CD117 (c-kit) staining, and negative margins of …

Quality control, accuracy, and prediction capacity of dual energy X-ray absorptiometry variables and data acquisition.

The acquisition of soft tissue measurements, fat (chemical) or adipose tissue (morphological) quantities, is essential in clinical research … , muscle, and bone from hind legs may give an incomplete picture of reality as one needs to measure viscera, connective tissue, and air pockets of the body. Validation studies with intact bodies are advised.

Studies on the toxicological effects of PFOA and PFOS on rats using histological observation and chemical analysis.

As an emerging class of environmentally persistent and bioaccumulative contaminants, perfluorinated compounds (PFCs), especially perfluorooc … arked hepatomegaly, renal hypertrophy, and orchioncus in treated groups were in accordance with the viscera-somatic indexes of the liver, kidney, and gonad. Histopathological observation showed that relatively serious damage occurred in the liver and lung, mainly including hepatocytic hypertrophy and cytoplasmic vacuolation in the livers and congestion an …

Pediatric lumbar Chance fractures in British Columbia: chart review and analysis of the use of shoulder restraints in MVAs.

Chance fractures of the skeletally immature spine classically occur in frontal motor vehicle accidents (MVAs) when the occupants are restrai … age from 3 to 16 with a mean age of 10.6 years. Eleven of the 26 (42%) patients sustained abdominal viscera injuries, seven of the 26 patients suffered neurologic injury (spinal cord and/or spinal nerve injury) associated with their spinal fracture, with two cases of complete paralysis, and there was a 38% incidence of head injury. Concomitant injuries (i …

Gallbladder cancer with duodenal infiltration: is it still resectable?

OBJECTIVE: To assess the resectability and the long-term survival in patients of gallbladder cancer with duodenal involvement. BACKGROUND: … hepatectomy, whereas the remaining 24 underwent segment IVB and V resection. Bile duct and adjacent viscera were resected when involved. Of the resected patients, eight underwent bile duct excision, seven had colonic resection, and three had vascular resection and reconstruction. The postoperative morbidity and mortality was 15 (34.9%) and three (6.97%), …

Intrauterine bacterial inoculation and level of dietary methionine alter amino acid metabolism in nulliparous yearling ewes.

Using an intrauterine bacterial inoculation method, our objective was to determine the effects of acute sepsis and level of dietary metaboli … ptake of Phe occurred throughout the sampling period, more Asp was released from the portal-drained viscera, and hepatic vein glucose concentrations were greater (P < 0.05). We conclude that Met seemed to be limiting in low-MM ewes, and as such, would continue to be limiting during sepsis. However, additional MM, in excess of the dietary requirement, woul …

Патогенез вируса гепатита мыши в гамма-интерферонно-дефицитных мышах модифицируется в результате совместного заражения геликобактром печени.

Гамма-интерферонно-дефицитные (IFN-gamma KO) мыши развили синдром пустой траты и обнаружили, что они совместно заражены с Helicobacter sp. и новой изолацией вируса гепатита мыши (MHV), названного MHV-G. Болезнь характеризовалась плевритом, перитонитом, гепатитом, пневмонией и менингитом. В ходе первоначальных экспериментов использовался цекальский однородный инокулум из клинических случаев, в которых содержались H. hepaticus и MHV-G, для воспроизведения развития перитонита и плевурита в мышах IFN-гамма KO. В отличие от этого, иммунокомпетентные мыши, учитывая тот же инокулум, развили острую, с

Совпадение в аннотации оригинала
Gamma interferon-deficient (IFN-gamma KO) mice developed a wasting syndrome and were found to be co-infected with Helicobacter sp., and a ne … intestinal tract, and acute peritonitis and pleuritis with adhesions on the serosal surfaces of the viscera. However, mice given H. hepaticus alone had minimal pathologic changes even though the organism was consistently detected in the cecum or feces. Although co-infection with H. hepaticus and MHV-G induced lesions similar to those associated with MHV-G …

Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.

Studies in mice lacking genes encoding for substance P or its receptor (NK1), or with NK1 antagonists, have shown that this system contributes to nociception, but the data are complex. Here, we have further examined the role of NK1 receptors in pain and hyperalgesia by comparing nociceptive responses to mechanical and chemical stimulation of viscera and the resulting hyperalgesia and inflammation in NK1 knockout (-/-) and wild-type (+/+) mice. We concentrated on visceral nociception because substance P is expressed by a much greater proportion of visceral than cutaneous afferents. NK1 -/- mice…

Microvascular prefabricated free skin flaps for esophageal reconstruction in difficult patients.

BACKGROUND: Reconstruction of the esophagus for complicated benign stricture or after resection of malignant lesion is still a challenge for surgeons. When abdominal viscera cannot be used, skin flaps are selected for esophageal reconstruction. However, skin flaps for esophageal reconstruction are notorious for leakage, and have not been widely accepted. Prefabrication before microvascular transfer to its final site can improve the result of esophageal reconstruction when skin flaps are used. METHODS: Eight patients with complicated corrosive esophagitis had been treated with prefabricated sk…

Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals.

Evidence suggests that the plasminogen activators (PAs), in particular urokinase-type PA (uPA), play a pivotal role in tumor invasion and me … ated microscopically for evidence of invasion. The regional lymph nodes, lungs, and solid abdominal visceral organs were sectioned and examined microscopically for evidence of metastatic disease. Cellular blue nevi were induced in 100% of uPA-/- and uPA+/+ promoted animals. Although a reduction in the radial and vertical progression of these lesions was n …

Compensatory responses and development of the nodose ganglion following ablation of placodal precursors in the embryonic chick (Gallus domesticus).

The nodose ganglion is the distal cranial ganglion of the vagus nerve which provides sensory innervation to the heart and other viscera. In this study, removal of the neuronal precursors which normally populate the right nodose ganglion was accomplished by ablating the right nodose placode in stage 9 chick embryos. Subsequent histological evaluation showed that in 54% of lesioned embryos surviving to day 6, the right ganglion was absent. Most embryos surviving to day 12, however, had identifiable right ganglia. In day 12 embryos, the right ganglion which developed was abnormal, with ganglion v…

Entrapment of the colon following diaphragmatic injuries: report of eight cases.

With a rise in the incidence of severe injuries, we are seeing increasing numbers of patients with colonic entrapment occurring at the sites … uries are suspected, an abdominal incision is necessary. In long-standing cases where the abdominal viscera are intact, the thoracic approach is preferable. At times, the combined thoraco-abdominal incision may be preferable. Diaphragmatic injuries resulting in colonic entrapment occurred most often in the left hemidiaphragm, which is relatively unprotect …

Toxoplasma gondii and Coxiella burneti antibodies among Brazilian slaughterhouse employees.

Previous studies have indicated toxoplasmosis and Q fever are potential hazards to persons who handle raw meat or who work in slaughterhouse … C. burneti was found in employees on the killing floor (36% positive) who were exposed to hides and viscera, but employees handling meat in the deboning or sausage section had prevalence levels of 20% and 14% respectively. Serologic testing of zebu cattle processed at the abattoir indicated that 10% of 124 tested had antibodies to T. gondii and 29% of 156 …

Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve.

The superior hypogastric plexus (SHP) and hypogastric nerves (HN) are components of the autonomic nervous system required for sympathetic regulation of the pelvic viscera. Despite their functional importance, the three-dimensional (3D) distribution and immunohistochemical composition of neurons in these structures remain poorly characterized. In this study, we used a multiscale imaging approach to generate a 3D anatomical and immunohistochemical characterization of the SHP and HN in adult humans. Both embalmed (body donor program) and unembalmed paraformaldehyde (PFA)-fixed specimens (organ do…

C3+ cancer-associated fibroblast-derived GAS6 promotes cervical cancer metastasis via activation of AXL signaling pathway in a syngeneic orthotopic mouse model.

BACKGROUND: Metastatic cervical cancer remains a leading cause of cancer-related death in women, although several mouse models of metastatic … cervical os and vaginal fornix. By day 14 post-injection, cancer cells had invaded into the pelvic viscera, particularly the rectum, and disseminated to regional lymph nodes. By day 28, distant metastases, predominantly in the lungs, were observed. Single-cell analysis revealed that crosstalk between cancer cells and T cells in LNMT promoted immune escap …

Porcine myogenesis in cloned wildtype and MYF5/MYOD/MYF6-null porcine embryo.

The pig is an important animal model increasingly used for biomedical research, particularly in transplantation strategies involving xenotra … ressive development of skeletal muscle in WT embryos but not in null embryos whereas development of viscera progressed equally in both groups. Molecular analyses highlighted dynamic changes in myogenic gene expression and myofiber formation, demonstrating an organized progression of myogenesis in WT embryos. Morphologically, the null embryos exhibited abn …

Utilizing Artificial Intelligence: Machine Learning Algorithms to Develop a Preoperative Endometriosis Prediction Model.

OBJECTIVE: To evaluate the predictive value of clinical features in the diagnosis of endometriosis by utilizing machine learning algorithms (MLAs), aiming to develop an accurate, explainable prediction model. DESIGN: Retrospective case-control study from 2011 to 2022. SETTING: Tertiary referral center specializing in pelvic pain and minimally invasive gynecologic surgery. PARTICIPANTS: All women aged 18 to 55 undergoing laparoscopic or robot-assisted excision of lesions of the ovary, pelvic viscera, or peritoneal surface by a single surgeon from 2011 to 2022. Exclusion criteria included wom…

Radiologic Assessment of Malpositioned Indwelling Catheters and Medical Devices: A Retrospective Case Series With Pictorial Review.

BACKGROUND: Indwelling medical devices such as central venous catheters (CVCs), ureteral stents, ventriculoperitoneal (VP) shunts, inferior … d proximal perforation through the renal cortex. VP shunt cases showed distal extrusion into hollow viscera such as the rectum. IVC filter malpositions included tilt, strut perforation, and extension into adjacent organs. PEG tube malpositions resulted in intraperitoneal leakage and peritonitis, while NG tube misplacements involved tracheobronchial insert …

Ureter as an Innocent Bystander: Presentation and Management in Unusual Vascular Compression Syndromes.

Objective Abdominopelvic vascular compression syndromes occur when the vascular structures either cause compression or are compressed by the surrounding hollow viscera. Apart from retrocaval ureter and UPJO (ureteropelvic junction obstruction), ureteric compression by other vascular structures is rare. We present five rare cases of ureter compression caused by the inferior mesenteric vein, testicular vein, ovarian vein, common iliac arteries, and an unnamed tributary of the inferior vena cava (IVC). Methods Retrospective data of all cases of hydroureteronephrosis between January 2019 and March…

Human anthrax in a non-epizootic area: epidemiological investigation and response based on One Health-Chengdu, China.

BACKGROUND: Anthrax, caused by Bacillus anthracis, is endemic in western China's pastoral regions. Urban areas adjacent to these regions fac … Aba Prefecture. B. anthracis was detected via qPCR in samples from a patient's skin lesions, beef, viscera, and forage; environmental samples were negative. Blood cultures showed no bacterial growth. Interventions included disinfection (10,000 mg/L chlorine), livestock culling, and incineration of traced beef. Approximately 30% of sold meat remained untr …