Результаты поиска

International comparison of the factors influencing reimbursement of targeted anti-cancer drugs.

BackgroundReimbursement policies for anti-cancer drugs vary among countries even though they rely on the same clinical evidence. We compared the pattern of publicly funded drug programs and analyzed major factors influencing the differences.MethodsWe investigated reimbursement policies for 19 indications with targeted anti-cancer drugs that are used variably across ten countries. The available incremental cost-effectiveness ratio (ICER) data were retrieved for each indication. Based on the comparison between actual reimbursement decisions and the ICERs, we formulated a reimbursement adequacy i

ESMO expert consensus statements on the screening and management of financial toxicity in patients with cancer.

BackgroundFinancial toxicity, defined as both the objective financial burden and subjective financial distress from a cancer diagnosis and its treatment, is a topic of interest in the assessment of the quality of life of patients with cancer and their families. Current evidence implicates financial toxicity in psychosocial, economic and other harms, leading to suboptimal cancer outcomes along the entire trajectory of diagnosis, treatment, supportive care, survivorship and palliation. This paper presents the results of a virtual consensus, based on the evidence base to date, on the screening an

Совпадение в полном тексте источника
… Counselling should be given by a dedicated professional (like a social worker) who can assess the patient’s economic situation, knows thoroughly the social security system of the jurisdiction and is aware of modalities to help the patient in his/her economic situation. … Counselling should be given by a dedicated professional (like a social worker) who can assess the patient’s economic situation, knows thoroughly the social security system of the jurisdiction and is aware of modalities to help the patient in his/her economic situation. …

Patient Perspectives on Palliative Care Outreach to Adults Living With Homelessness.

ImportancePeople experiencing homelessness face higher rates of early mortality, multimorbidity, and unmet needs at the end of life, but despite these risks, they often encounter systemic barriers to accessing palliative care. Outreach-based models have emerged to address this gap, yet little is known about how these models are perceived by those receiving care.ObjectiveTo evaluate a palliative care outreach intervention, the Palliative Education and Care for the Homeless (PEACH) program, from the perspective of patients living with homelessness and life-limiting illness.Design, setting, and p

Effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer: A systematic review and meta-analysis.

BackgroundTelehealth is being integrated with palliative care for patients with advanced cancer to improve access to specialized palliative care. However, its effectiveness and implementation requirements in palliative care remain unclear.AimThis study evaluates the effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer.DesignThis was designed as a systematic review and meta-analysis with narrative synthesis (registered; CRD42024581786). The effects on patients' quality of life, symptom burden, and depression were analyzed using a rando

Using virtual reality hypnosis during stem cell transplant for patients in hematology: A protocol for a feasibility randomized study.

BackgroundStem cell transplantation is a highly stressful treatment for hematological cancer patients, negatively impacting their quality of life. Hypnosis has proven effective in managing symptoms like pain, fatigue, and anxiety, and improving quality of life. Virtual reality (VR) is used in cancer treatments to distract from pain, and combining VR with hypnosis (VRH) could enhance the hypnotic experience. However, methodological limitations in current studies prevent clear evaluation of its effectiveness, particularly for individualized care and psychosocial interventions.Aims1) To evaluate

Clinical Trials of Stem Cell Therapy in Japan: The Decade of Progress under the National Program.

Stem cell therapy is a current world-wide topic in medical science. Various therapies have been approved based on their effectiveness and put into practical use. In Japan, research and development-related stem cell therapy, generally referred to as regenerative medicine, has been led by the government. The national scheme started in 2002, and support for the transition to clinical trials has been accelerating since 2011. Of the initial 18 projects that were accepted in the budget for preclinical research, 15 projects have begun clinical trials so far. These include the transplantation of retin

Расовые различия в выживании нескольких миелом: ассоциации с трансплантацией стволовых клеток, страхованием и расширением сети медицинских учреждений.

На уровне населения чернокожие пациенты с множественной миеломой (ММ) могут выжить хуже, чем белые. Авторы изучили вопрос о том, как автологическая трансплантация стволовых клеток (ASCT), страхование и расширение сети " Медикэйд " связаны с расовыми различиями в общем уровне выживания (rwOS) в реальном мире. МЕТОДЫ: Данные, полученные 4932 больные MM (MM)24% Блэк) в Флатиронской базе данных исследований в области здравоохранения анализировался с использованием моделей " Кокс регрессиал " (rwOS), " Файн энд срей " (ASCT) и " политомная регрессия " (страхо

Совпадение в полном тексте источника
… Am J Hematol . 2014 ; 89 ( 8 ): 825 ‐ 830 . doi: 10.1002/ajh.23753 24799343 22 Social Security Administration . Disability Benefits: Approval Process . Social Security Administration ; 2026 . … Accessed June 9, 2026. https://www.ssa.gov/benefits/disability/approval.html 23 Social Security Administration . Medicare Information for People with Disabilities . Social Security Administration ; 2026 . …

Воздействие систем телемониторинга на лечение раковых заболеваний: систематический обзор.

В рамках этого систематического обзора оценивается воздействие, пригодность для использования, техническая эффективность и применение систем телемониторинга при лечении рака у взрослых. Этот систематический обзор проводился в соответствии с предпочтительными принципами отчетности для системных обзоров и мета-анализов и коллегиального обзора стратегий электронного поиска. Пубмед, МЕДЛИНА и КИНАХЛ были обысканы с июня 2013 по март 2025. Термины " поиск " охватывают лечение раковых заболеваний, системы телемониторинга, мобильное медицинское обслуживание (медицинское здоровье), электронн

A real-world comparative analysis of carfilzomib and other systemic multiple myeloma chemotherapies in a US community oncology setting.

BackgroundMost multiple myeloma (MM) patients ultimately progress, with remission duration decreasing after first relapse. Recently, novel agents have been approved for the treatment of relapsed MM. There is a paucity of real-world data on these treatments. We sought to compare time to next treatment (TTNT) in MM patients in their second line of therapy (LOT2), treated with common proteasome inhibitor (PI)-based triplets.MethodsAdult MM patients who received carfilzomib (K) between 1 November 2013 and 29 February 2016 at US Oncology Network (USON) clinics utilizing iKnowMed™ electronic health

Совпадение в полном тексте источника
… To supplement the data available in iKM on vital status and dates of death, the Social Security Death Index (SSDI) was used. … The SSDI, which is maintained by the Social Security Administration, includes records of deaths reported by family members, funeral homes, hospitals, financial institutions, and federal agencies for individuals who have a social security number. …

The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels.

UNLABELLED: The 2022 report of the Lancet Countdown is published as the world confronts profound and concurrent systemic shocks. Countries and health systems continue to contend with the health, social, and economic impacts of the COVID-19 pandemic, while Russia’s invasion of Ukraine and a persistent fossil fuel overdependence has pushed the world into global energy and cost-of-living crises. As these crises unfold, climate change escalates unabated. Its worsening impacts are increasingly affecting the foundations of human health and wellbeing, exacerbating the vulnerability of the world’s pop

Future Patient Incidence in Hemato-Oncology: A Study Using Data from Cancer Registries in Japan.

PurposeThe distribution of patients with hematological malignancies is expected to change markedly in the future due to aging of the Japanese population. We assessed the expected incidence rates of leukemia, malignant lymphoma, and multiple myeloma using national population estimates and data from the Kanagawa Cancer Registry.Patients and methodsTo evaluate the effects of community aging, we compared expected future incidences of hematological malignancies in Kanagawa with other three areas, namely the Yamagata, Osaka, and Nagasaki prefectures, which have different populations and predicted ag

Совпадение в полном тексте источника
… Estimated data for 2015, 2020, 2025, 2030, and 2035 populations were retrieved from the National Institute of Population and Social Security Research. 14 Patients with hematological malignancy identified by DCO were excluded from the study because detailed information, such as incidence data and diagnosis … National Institute of Population and Social Security Research. Estimates of the nation’s population trends by region 2010–2040. [Home page on the internet]; 2013. Available from: http://www.ipss.go.jp/pp-shicyoson/j/shicyoson13/t-page.asp . …

Viewing the US presidential electoral map through the lens of public health.

Health, disease, and mortality vary greatly at the county level, and there are strong geographical trends of disease in the United States. Healthcare is and has been a top priority for voters in the U.S., and an important political issue. Consequently, it is important to determine what relationship voting patterns have with health, disease, and mortality, as doing so may help guide appropriate policy. We performed a comprehensive analysis of the relationship between voting patterns and over 150 different public health and wellbeing variables at the county level, comparing all states, including

Совпадение в полном тексте источника
… While still important to Republican voters, it fell behind the issues of terrorism, the economy, social security, immigration, and the military, with an 18 point gap between Democrat and Republican voters on the issue of health care costs and a 13 point gap on the issue of Medicare reform [ 2 ]. … Trump said he wouldn’t cut Medicaid, Social Security, and Medicare. His 2020 budget cuts all 3. Vox. 2019 [cited 2021 Jun 28]. Available from: https://www.vox.com/policy-and-politics/2019/3/12/18260271/trump-medicaid-social-security-medicare-budget-cuts . …

A cross-sectional study of the socio-demographic and epidemiological factors associated with childhood cancer in Cali, Colombia.

This study investigates the occurrence of childhood cancer between the years 2015 and 2016 in the city of Cali, Colombia, with respect to: a) sociodemographic characteristics, b) type of cancer, c) epidemiological weeks of cancer and d) comparative survival according to health system affiliation by consolidating the records notified to the municipal health secretariat. Statistically significant differences were found between the groups analysed in relation to the variables related to the type of cancer (p = 0.006). With respect to the proportion of cancer mortality between the years 2015-2016

Совпадение в полном тексте источника
… Figure 1 Table 2 shows the comparison by social security health regime and type of cancer according to year of notification. Table 2 Average and medium of survival times by social security health regime and type of cancer in children under 18 years of age according to year of notification. … Table 2 Average and medium of survival times by social security health regime and type of cancer in children under 18 years of age according to year of notification. Cali-Colombia, 2015 and 2016. a The estimate is limited to the longest survival time, if censored. ∗ Log Rank (Mantel-Cox). …

Prices and Clinical Benefit of National Price-Negotiated Anticancer Medicines in China.

BackgroundHigh prices of anticancer medicines have increased the economic burden for both patients and health insurance systems. Since 2017, China has implemented national price negotiations for medicines, relying on evidence from health technology assessments. We aim to assess the relation between negotiated price and value of anticancer medicines listed in China's National Reimbursement Drug List (NRDL).MethodsFor all price-negotiated anticancer medicines and corresponding indications listed in the latest NRDL between 2017 and 2020, we collected their clinical outcomes data, including overal

Совпадение в полном тексте источника
… Ministry of Human Resources and Social Security. … Notice of the ministry of human resources and social security on issuing the national drug catalog for basic medical insurance, work- related injury insurance, and maternity insurance. 2021. http://www.mohrss.gov.cn/SYrlzyhshbzb/shehuibaozhang/zcwj/yiliao/201707/t20170718_274153.html 26. …

Were economic evaluations well reported for the newly listed oncology drugs in China's national reimbursement drug list.

PurposeTo assess the reporting quality of published economic evaluations of the negotiated oncology drugs listed for China's 2020 National Reimbursement Drug List (NRDL).MethodsA comprehensive search was conducted to identify economic evaluation studies of negotiated oncology drugs listed in China's 2020 NRDL using the PubMed/MEDLINE, Embase, Web of Science, CNKI, SinoMed, and WanFang Database up to March 31, 2021. The Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist scored the reporting quality between 0 and 100. A linear regression analysis was employed to exami

Совпадение в полном тексте источника
… Notice of the ministry of human resources and social security on the inclusion of 36 drugs in the category B of the national basic medical insurance, work injury insurance and maternity insurance drug list. http://www.gov.cn/xinwen/2017-07/19/content_5211741.htm#2 . 13. … Administration (NHSA) and Ministry of Human Resources and Social Security (MOHRSS). http://www.nhsa.gov.cn/art/2020/12/28/art_37_4220.html . 23. Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, Augustovski F, Briggs AH, Mauskopf J, Loder E. …

Hematological cancer patients' social support, coping strategies, anxiety, depression and posttraumatic growth: a structural equation model.

ObjectivePosttraumatic growth (PTG), defined as positive psychological changes following traumatic events, has been observed in some hematological cancer patients during their disease course. These changes, encompassing shifts in life perspective, interpersonal relationships, and self-perception, are critical for psychological recovery. However, the interplay of social support, coping strategies, anxiety, and depression in shaping PTG remains unclear. Therefore, the aim of this study was to explore these associations in hematological cancer patients using a hypothetical model.MethodsFrom Augus

A latent profile analysis of financial toxicity and its association with anxiety and depression in patients with hematologic malignancies.

OBJECTIVE: To identify latent subgroups of financial toxicity among patients with hematologic malignancies, examine associated sociodemographic and clinical predictors, and explore the relationship between financial toxicity and anxiety-depression symptoms. METHODS: A cross-sectional study was conducted among 486 patients with hematologic malignancies recruited through convenience sampling from provincial-level hospitals in Hunan Province, China. Participants completed the General Information Questionnaire, the Patient-Reported Outcome Financial Toxicity (PRO-FT) Scale, the Patient Health Que

Совпадение в полном тексте источника
… Chinese insurance system is a social security mechanism that provides financial support to retirees through mandatory or voluntary contributions. 31 The risk characteristics of patients without medical insurance are particularly prominent. 11 , 31 Against the gradual improvement of the Chinese multi-level …

Множественная миелома у людей трудоспособного возраста в Германии, Польше и Чехии: результаты качественного исследования.

ЦЕЛЬ: Цель исследования состояла в том, чтобы понять опыт взрослых трудоспособного возраста с миеломой и их партнерами/членами семьи, проживающими в Германии, Чешской Республике и Польше. МЕТОДЫ: КОНСУЛЬТАТИВНЫЕ СООБРАЖЕНИЯ 36 взрослых трудоспособного возраста, живущих с миеломой, и three Члены семьи. Данные были собраны в период с мая по октябрь 2022. К данным был применен тематический анализ. Результаты: Описано медицинское обслуживание и государственная поддержка в каждой стране. Степень участия в трудовой деятельности зависит от бремени симптомов пациентов, потребностей в лечении, государс

Совпадение в полном тексте источника
… Setting Three countries — Czechia, Germany, and Poland — were chosen to allow for diversity in sociocultural context, and its impact on social security, work, and health services. …

Health-Related Quality of Life and Satisfaction With Health Care: Relation to Clinical Stage in Mexican Patients With Multiple Myeloma.

Multiple myeloma (MM) is characterized by bone pain, pathologic fractures, bone destruction, and secondary hypercalcemia, all these conditions impact on health-related quality of life of patients. The objective was to evaluate the global health state and health-related quality of life in a group of patients with MM who attended a tertiary health-care center of the Instituto Mexicano del Seguro Social in Mexico, through the questionnaires designed by European Organization for Research and Treatment of Cancer (EORTC) quality of life group. Exploratory cross-sectional study in patients with MM tr

Совпадение в полном тексте источника
… Data of each patient were managed confidentially and anonymously; data were analyzed and identified by the social security number. Patients signed the institutional informed consent form. … Evaluation of health-related quality of life in patients with non-Hodgkin lymphoma and colorectal cancer at different stages, attending the Mexican Institute of Social Security. Value Health. 2011;14(5 suppl 1):S130–S132. doi: 10.1016/j.jval.2011.05.031. 20. …

The impact of the COVID-19 pandemic on the oncology services demand in a middle-income setting with universal health insurance.

AimWe analyze the impact of the COVID-19 pandemic on oncology service demand in a middle-income country with universal health coverage.MethodsWe collected data from January 1st-2017 to December 31th-2021 at a reference center in Bogotá-Colombia regarding first-time consultations of cross-cutting services (clinical oncology, hematology, palliative care, radiation oncology); specialized multidisciplinary units (breast, prostate, lung, stomach); inpatient and outpatient systemic therapy; radiotherapy; oncology surgery; and bone marrow transplant. A descriptive time series analysis was performed,