Результаты поиска

The prevalence of neuropathic pain pathophysiology associated with ankle fracture: A study protocol.

Chronic pain is prevalent among U.S. military personnel and often accompanied by comorbid behavioral health disorders and other medical cond … lth Systems (MHS), and that this population is disproportionately affected by lost duty days, early retirement, loss of readiness, and increased burden to the MHS. To date, the Department of Defense (DOD) and MHS have emphasized multimodal, multidisciplinary, stepped treatment for chronic pain that prioritizes nonpharmacologic therapies and non-opioid pain m …

Planning for the future following receipt of Alzheimer's disease risk estimate among Latinos in New York City.

BackgroundAlzheimer's disease (AD), a debilitating incurable neurodegenerative disorder, causes progressive deterioration in memory, languag … sted to be placed in a nursing home if they developed AD. Some contemplated making changes to their retirement plans to ensure access to their informal support networks for future care needs. Others with future financial concerns started to save more money and investigate their social security/employee benefits. Several started to get their financial/legal a …

Merkel Cell Carcinoma With Lymph Node Metastasis: A Case Emphasizing Early Diagnosis and Multidisciplinary Management.

Merkel cell carcinoma (MCC) is a rare but exceptionally aggressive neuroendocrine skin cancer, characterized by low global incidence yet sig … nt outcomes. Key risk factors include advanced age, with an exponential increase in incidence after retirement age, immunosuppression, and chronic sun/UV exposure. Merkel cell polyomavirus has been identified as an important etiologic factor in the majority of cases. This case report describes an elderly female patient who presented with a rapidly growing, u …

Экономическое бремя вторичного прогрессивного множественного склероза: исследование DISCOVER.

ОКРУЖАЮЩАЯ СРЕДА: Оценить социально-экономическое бремя людей со вторичным прогрессивным множественным склерозом (ПВСПМС), принимая во внимание прямое медико-санитарное обслуживание, прямое немедицинское обслуживание и косвенные издержки, а также оценить взаимосвязь между издержками и функциональными результатами пациентов. МЕТОДЫ: Изучение наблюдений, перекрестных и многоцентральных исследований с ретроспективным сбором данных о реальной клинической практике, полученных в ходе посещения служб неврологии 34 Больницы в период 2019-2020. Клинические данные включали в себя оценки по расширенной ш

Совпадение в аннотации оригинала
BACKGROUND: To estimate the socioeconomic burden of people with secondary progressive multiple sclerosis (pwSPMS), considering direct health … for domestic/housekeeping tasks. More than 90% were inactive at work, with nearly 80% taking early retirement. The estimated total annual cost per pwSPMS in Spain was almost €41,500, of which more than 50% (€21,400) were indirect costs, followed by direct health care costs (30%, €11,300), and, finally, direct non-health care costs (about 20%, €8,800). Older …

Breast cancer survivorship needs: a qualitative study.

BACKGROUND: Breast cancer rates and the number of breast cancer survivors have been increasing among women in Iran. Effective responses from … d. The analysis focused on four central themes: (1) financial toxicity (healthcare costs, unplanned retirement, and insurance coverage of services); (2) family support (emotional support, Physical support); (3) informational needs (management of side effects, management of uncertainty, and balanced diet); and (4) psychological and physical issues (pain, fati …

Associations of type 2 diabetes and the risk of migraine in Chinese populations.

AIM: We aimed to explore the relationship between type 2 diabetes mellitus (T2DM) and the incidence rate of migraine in a Chinese population, and analyze the clinical characteristics of migraine patients with T2DM. METHODS: Data on the study cohort of 9873 individuals were obtained from the China Health and Retirement Longitudinal Study (CHARLS). The incidence rate of migraine from 2015 to 2018 was assessed. The Cox proportional hazards model was used to estimate hazard ratios (HRs) and their 95% confidence intervals (CIs) for the relationship between T2DM and the incidence of migraine. In ad…

Triglyceride glucose index combined with body mass index and its 4-year change with the risk of hypertension in middle-aged and older Chinese: A prospective cohort study.

BACKGROUND AND AIM: To explore the association of triglyceride glucose index-body mass index (TyG-BMI) and its dynamic changes with the risk of hypertension among middle-aged and older Chinese adults based on a large-sample prospective cohort study. METHODS AND RESULTS: Participants over 45 years old and without a history of hypertension were included from the China Health and Retirement Longitudinal Study registry. Data were collected in 2011 and followed up in 2015. TyG index and TyG-BMI were calculated as ln (triglyceride∗glucose/2) and TyG index∗BMI, respectively. We performed multivariat…

Forecasting the 20-Year Incidence of Dementia by Socioeconomic Status, Race/Ethnicity, and Region Based on Mid-Life Risk Factors in a U.S. Nationally Representative Sample.

BACKGROUND: Alzheimer's disease and related dementias (ADRD) incidence varies based on demographics, but mid-life risk factor contribution t … ctors, Aging, and Incidence of Dementia (CAIDE) prediction model to the 2006 wave of the Health and Retirement Study (HRS) in participants aged 45 to 64 to estimate the 20-year risk of incident ADRD. RESULTS: The 20-year risk of dementia among middle-aged Americans was 3.3% (95% CI: 3.2%, 3.4%). Dementia incidence was forecast to be 1.51 (95% CI: 1.32, 1.71 …

The structure, function, and quality of the social convoy for improvements in depressive symptoms in urban and rural China: A 3-year longitudinal cohort study.

OBJECTIVE: To delve into the intricate relationship between the social convoy characteristics and the improvement in depressive symptoms (IDS) over three years among middle-aged and older adults in China, focusing on the potential moderating role of the rural-urban divide. METHODS: The study analyzed data from 2229 respondents aged 45 and above from the 2015 and 2018 surveys of China Health and Retirement Longitudinal Study (CHARLS). The 10-item Center for Epidemiologic Studies Depression Scale was used to determine the presence of depressive symptoms. Questions on social support, social netw…

Novel anthropometric indices are superior adiposity indexes to portend visual impairment in middle-aged and older Chinese population.

OBJECTIVE: To investigate differential associations of traditional and novel adiposity indices with visual impairment (VI) in the middle-aged and older Chinese population. METHODS AND ANALYSIS: Based on the China Health and Retirement Longitudinal Study, 7750 Chinese older adults aged over 45 were included at baseline 2011, and 4133 participants who accomplished all three interviews from 2011 to 2015 were adapted for longitudinal analyses. We enrolled six adiposity indices, including the body mass index (BMI), waist-to-height ratio (WHtR), weight-adjusted-waist index (WWI), a body shape index…

The association between abdominal obesity and depressive symptoms among Chinese adults: Evidence from national and regional communities.

BACKGROUND: The association between body shape and depressive symptoms has been reported in adults. The present study aimed to investigate the association between body shape-specific abdominal obesity and depressive symptoms among multi-regional Asian adults. METHODS: The 2011-2012 China Health and Retirement Longitudinal Study and 2022-2023 Hangzhou study were used as the discovery and validation datasets, respectively. Body shape was assessed by body mass index categories. Abdominal obesity was defined as a body shape index (ABSI) ≥ 75th centile. Depression was measured using 10-item Centre…

Joint daily functional trajectory and risk of new-onset Alzheimer's disease and related dementias in older adults with normal and abnormal weight.

BACKGROUND: Associations between daily functional trajectories and new-onset all-cause dementia and Alzheimer's disease (AD) and the role of body weight are underexplored. METHODS: Data were from the Health and Retirement Study (HRS) 1994-2020. Daily function was assessed using (instrumental) activities of daily living ([I]ADLs). All-cause dementia and AD were defined by self- or proxy-reported physician diagnoses. Body weight was assessed using body mass index (BMI) and categorized as normal (18.5 kg/m2 ≤ BMI < 30 kg/m2) and abnormal (BMI < 18.5 kg/m2 or ≥30 kg/m2). The group-based trajector…

Gender differences in self-rated health among older adults in the Chinese workforce.

INTRODUCTION: This study investigates gender-based disparities in self-rated health among older individuals in the Chinese workforce, utilizing data from the China Health and Retirement Longitudinal Study (CHARLS). Understanding these health gaps is crucial for crafting effective health policies and interventions in light of the rapidly aging population. MATERIALS AND METHODS: Data from the 2020 CHARLS survey, comprising Chinese individuals aged 45 and above, were analyzed, focusing on older adults actively employed. Descriptive statistics and regression analyses examined gender discrepancies…

Influence of multimorbidity and socioeconomic position on long-term healthcare utilization and prognosis in patients after cardiac resynchronization therapy implantation.

AIMS: We aimed to investigate the influence of socioeconomic position (SEP) and multimorbidity on cross-sectional healthcare utilization and … ds regression. We followed 2007 patients (median age of 70 years), 79% were male, 75% were on early retirement or state pension, 37% were living alone, and 41% had low education level for a median of 5.2 [inter-quartile range: 2.2-7.3) years. In adjusted regression models, a higher number of chronic conditions were associated with increased healthcare utiliz …

Comparing Neighbors and Friends in Age-Related Network Changes.

OBJECTIVES: To assess how the role of neighbors and friends in people's networks changes with age and how this is affected by cohort, marria … ople than for married people, but this gap declined with age. The share of neighbors increased with retirement, especially for men. The share of neighbors vis-à-vis friends was also larger for people with less income and education and this gap did not change with age. DISCUSSION: In the nonkin part of older adults' networks, proximity eventually becomes dom …

Childhood intra- and extra-familial maltreatment and later-life trajectories of depressive symptoms: evidence from China.

BACKGROUND: Both late-life depression and childhood maltreatment have become major global public health issues, given their prevalence and s … hinese context. METHODS: Hierarchical linear models were applied to data from the China Health and Retirement Longitudinal Study (2011-2018, N = 12,669 individuals aged 45 to 80, comprising N = 43,348 person-years). Depressive symptoms were measured by the CES-D-10 scale. Childhood intra-familial maltreatments were measured by physical abuse and emotional n …

Adverse childhood experiences, sarcopenia, and social participation in older adults: a cohort study.

OBJECTIVES: To examine the relationships between adverse childhood experiences (ACEs) and developing sarcopenia in older adults and the modifying effects of active social participation. METHODS: This prospective cohort study used survey data from the China Health and Retirement Longitudinal Study, including baseline surveys from 2011, follow-up data from 2013, follow-up data from 2015, and information on ACEs from the 2014 Life History Survey. Information concerning 10 ACEs, including five threat-related ACEs and five deprivation-related ACEs before 17 years of age was obtained by questionnai…

Association of High-Density Lipoprotein Cholesterol with Sarcopenia in Chinese Community-Dwelling Middle-Aged and Older Adults: Evidence from 4-Year Longitudinal Study.

INTRODUCTION: There is inconsistent evidence on the associations between high-density lipoprotein cholesterol (HDL-C) and risk of sarcopenia. The aim of the study was to determine the evidence existing between HDL-C and sarcopenia in Chinese middle-aged and older adults. METHODS: We used a panel study design of the China Health and Retirement Longitudinal Study (CHARLS), with 7,415 participants (mean age 57.5 years) from 2011, 2013, and 2015. HDL-C was measured by colorimetric test of venous serum samples. Sarcopenia was defined as low muscle mass, plus low muscle strength, or low physical pe…

Associations between housing quality and sarcopenia among older adults: evidence from China and India.

OBJECTIVES: Housing is an important social determinant of health. However, limited studies have focused on the relationship between housing quality and sarcopenia, especially in low- and middle-income countries. This study aims to examine the association between housing quality and sarcopenia in older adults in China and India. METHODS: The study was based on the China Health and Retirement Longitudinal Study and Longitudinal Aging Study in India. Housing quality was evaluated by five indicators, including housing materials, water sources, sanitation facilities, main fuel for cooking, and ava…

Novel Insight into the Association between Balneotherapy and Functional State and Health Perception in Chronic Low Back Pain: A Cross-Sectional Study.

Background: Epidemiological data indicate that low back pain (LBP) affected 619 million people globally in 2020, representing a significant health and economic burden. Additionally, chronic LBP (cLBP) strongly impairs quality of life and leads to disability and premature retirement, thus emphasizing the need for providing deeper insight into the factors that affect treatment outcomes and for offering thorough guidance for the assessment and management of this condition. Taking into consideration the rising prevalence of cLBP and the knowledge gap referring to the overall health benefits of bal…