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Обнаружение новых листьев с использованием большой языковой модели: прикладные программы в массивах данных с множественным склерозом в реальном мире.

ЦЕЛЬ: Нейроимация обычно используется для выявления новых видов подстрекательской деятельности при множественном склерозе (МС). Крупная языковая модель классификации описей магнитного резонанса в электронной медицинской записи (ЭПЧ) в качестве дискретных данных может принести значительные выгоды для исследований в области НР. Цели нынешнего исследования заключались в разработке такой оперативной иллюстрации его исследовательской деятельности на основе общего клинического сценария: мониторинг реакции на разрушающую клетки B (BCDT). МЕТОДЫ: Институциональная экосистема, которая надежно увязывает

Use of remote blood releasing system for red cell transfusion in hospice care center.

ObjectivesIt is quite common to have advanced cancer or end-stage renal disease patients for regular or even frequent blood transfusion in palliative care. However, due to geographical reason in some hospice centers, blood transfusion is sometimes difficult if blood bank is closed during non-office hour or not available.MethodsHere, we reported a new blood releasing system, that is, remote blood releasing system, that could be used safely by nursing staff alone when the blood bank was closed during the night time and holiday.ResultsOn-call nursing staff could collect red cells successful in th

Histopathological study of Enterobius vermicularis among appendicitis patients in Gaza strip, Palestine.

OBJECTIVES: Relatives of long-term missing persons need to deal with uncertainties related to the disappearance. These uncertainties may give rise to ruminative thinking about the causes and consequences of the loss. Focusing on tolerating uncertainties in treatment of relatives of missing persons might foster recovery. Adding mindfulness to cognitive behavioural therapy might serve this aim. The feasibility and potential effectiveness of cognitive behavioural therapy with mindfulness were evaluated in a pilot study. We aimed to detect changes in symptom levels and mindfulness from pre-treatme

Second-Class Care: How Immigration Law Transforms Clinical Practice in the Safety Net.

This article examines how U.S. immigration law extends into the health care safety net, enacting medical legal violence that diminishes noncitizens' health chances and transforms clinical practices. Drawing on interviews with health care workers in three U.S. states from 2015 to 2020, I ask how federal citizenship-based exclusions within an already stratified health care system shape the clinical trajectories of noncitizens in safety-net institutions. Focusing specifically on cancer care, I find that increasingly anti-immigrant federal policies often reshape clinical practices toward noncitize

Характеризация качества жизни и её полезность как показателя здоровья для людей с глубокими интеллектуальными и множественными нарушениями: обзор первичных исследований.

БАКGROUND: Установление эффективности вмешательств, способствующих улучшению качества жизни, является важным для предоставления обоснованной медицинской помощи, оптимизации результатов и обоснования расходов на такую поддержку. Настоящий обзор исследует, как качество жизни у взрослых с глубокими интеллектуальными нарушениями характеризуется, измеряется и используется для оценки здравоохранительных вмешательств в научной литературе. МЕТОДЫ: Проведена скопинг-ревью первичных исследований, опубликованных с 2010 по 2024 год, в базах данных CINAHL, MEDLINE, APA PsycINFO, APA SocIndex, Education So

Impact of the National Health Insurance Coverage Policy on the Utilisation and Accessibility of Innovative Anti-cancer Medicines in China: An Interrupted Time-Series Study.

Objective: The study aimed to evaluate the impact of the National Health Insurance Coverage (NHIC) policy on the utilisation and accessibility of innovative anti-cancer medicines in Nanjing, China. Methods: We used the adjusted World Health Organisation and Health Action International methodology to calculate the price and availability of 15 innovative anti-cancer medicines included in the National Health Insurance drug list in 20 tertiary hospitals and six secondary hospitals in Nanjing before and after NHIC policy implementation. Interrupted time-series regression was used to analyse the cha

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… In China, the high cost of cancer treatment has become a major issue in the area of social security. … Jiangsu province department of human resources and social security . Notice of Jiangsu provincial department of human resources and society on the inclusion of 36 drugs into list of basic medical insurance, industrial injury insurance and maternity insurance. (2017). …

Telemedicine With Wearable Technologies in Patients Undergoing Hematopoietic Cell Transplantation and Chimeric Antigen Receptor T-Cell Therapy (TEL-HEMATO Study): Prospective Noninterventional Single-Center Study.

BackgroundPatients with hematological malignancies receiving hematopoietic cell transplantation (HCT) or chimeric antigen receptor (CAR) T-cell therapy are at risk of developing serious clinical complications after discharge.ObjectiveThe aim of the TEL-HEMATO study was to improve our telehealth platform for the follow-up of patients undergoing HCT or CAR T-cell therapy during the first 3 months after discharge with the addition of wearable devices.MethodsEleven patients who received autologous (n=2) or allogeneic (n=5) HCT or CAR T-cell therapy (n=4) for hematological malignancies were screene

Взгляд румынских пациентов на непрерывную терапию миеломы.

UNLABELLED: В последние годы изменилась парадигма лечения множественной миэломы (ММ), поскольку непрерывная терапия становится стандартом ухода за вновь диагностированными и рецидивированными пациентами. Хотя не вызывает сомнений тот факт, что непрерывная терапия принесла большую пользу как без прогрессирования, так и с точки зрения общего выживания, до сих пор не ясно, какова точка зрения пациентов на этот терапевтический подход. МЕТОДЫ: Это исследование включало в себя 155 Взрослые пациенты ММ из Клинического института Фундэни в Румынии получают непрерывную терапию с помощью дратумумаба, про

The 2019 report of The Lancet Countdown on health and climate change: ensuring that the health of a child born today is not defined by a changing climate.

UNLABELLED: The Lancet Countdown is an international, multidisciplinary collaboration, dedicated to monitoring the evolving health profile of climate change, and providing an independent assessment of the delivery of commitments made by governments worldwide under the Paris Agreement. The 2019 report presents an annual update of 41 indicators across five key domains: climate change impacts, exposures, and vulnerability; adaptation, planning, and resilience for health; mitigation actions and health co-benefits; economics and finance; and public and political engagement. The report represents th

Socioeconomic and physical health status changes after visual impairment in Korea using difference-in-difference estimations.

This study analyzed the impact of visual impairment on socioeconomic and physical health status and its heterogeneity by severity of visual impairment. We used nationally representative cohort data based on Korean national health insurance claims (2002-2013), which were extracted for 11,030 persons (2206 visually impaired, 8824 control). This was restructured as monthly data for each person (person-month). Multivariate and ordered logistic regressions were conducted, and the pre-impairment status between the visually impaired and non-visually impaired people was adjusted by difference-in-diffe

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… Korea operates a social security system, which includes disability pensions for people with severe disabilities, disability allowances for people with mild disabilities, and an obligatory employment system for disabled people to secure income and employment 20 – 22 . … External validity is established given that people with disabilities in Korea are entitled to targeted assistance from the social security system and adjusted premiums for health insurance. …

Body composition predictors of mortality in patients undergoing surgery for long bone metastases.

Background and objectivesBody composition measurements using computed tomography (CT) may serve as imaging biomarkers of survival in patients with and without cancer. This study assesses whether body composition measurements obtained on abdominal CTs are independently associated with 90-day and 1-year mortality in patients with long-bone metastases undergoing surgery.MethodsThis single institutional retrospective study included 212 patients who had undergone surgery for long-bone metastases and had a CT of the abdomen within 90 days before surgery. Quantification of cross-sectional areas (CSA)

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… Date of death was obtained from medical charts and the Social Security Index. 28 Loss to follow‐up in survival was 5.2% (11/212) at 90 days and 8.0% (17/212) at 1 year. Follow‐up was verified until May 15th, 2020. … Social Security Administration : Social Security Death Index, 2014. 29. Forsberg JA, Eberhardt J, Boland PJ, Wedin R, Healey JH, El‐Deiry WS. Estimating survival in patients with operable skeletal metastases: an application of a bayesian belief network. PLoS One. 2011;6:e19956. 30. …

Availability of secondary healthcare data for conducting pharmacoepidemiology studies in Colombia: A systematic review.

Real-world evidence (RWE) is emerging as a fundamental component of the post-marketing evaluation of medicinal products. Even though the focus on RWE studies has increased in Colombia, the availability of secondary data sources to perform this type of research is not well documented. Thus, we aimed at identifying and characterizing secondary data sources available in Colombia. We performed a systematic literature review on PubMed, EMBASE, and VHL using a combination of controlled vocabulary and keywords for the concepts of electronic health records, epidemiologic studies and Colombia. A total

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… Even though there are government‐led information systems and a single‐payer healthcare system, the collection of data is not always complete. 10 , 11 The Colombian health system includes a social security system with public funding and a less preeminent private sector. … Antidepressant prescription patterns in patients affiliated with the general social security health system of Colombia. Rev Panam Salud Publica. 2011;30:461‐468. 135. Machado‐Alba JE, Morales‐Plaza CD. …

Искусственный интеллект и наука о вкладе пациента: точка зрения людей с множественным склерозом.

Искусственный интеллект (АИ) может сыграть жизненно важную роль в переходе к прогнозной, профилактической и индивидуализированной медицине при условии, что мы руководствуемся наукой с помощью и с помощью пациента. Меры по достижению результатов, о которых сообщают пациенты (ПРОМ), представляют собой уникальную возможность для получения практических знаний от людей, живущих в условиях здоровья, и обеспечения их научной актуальности для всех других заинтересованных сторон. Несмотря на это, использование стандартизированных результатов, включая ПРОМ, в рамках научно-исследовательской системы и си

Анализ затрат и последствий для бюджета в отношении подкожного Натализумба в случае повторного выброса нескольких склерозов в Италии.

ЦЕЛЬ: Two Для оценки экономических и финансовых последствий подкожного (СК) и внутривенного (IV) внутриутробного (ВД) внутриутробного (ВД) родовспоможения с точки зрения времени управления и затрат в итальянской среде с точки зрения центра склероза (МС), пациента и общества были проведены анализы, сведение к минимуму затрат и последствия для бюджета. ПАТИЕНТЫ И МЕТОДЫ: Анализ минимизации затрат (КМА) принял модель Маркова с three В его основу положены результаты исследования REFINE и его пост-специального анализа, в ходе которого была произведена оценка и продемонстрирована неприязнь к формуле

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… With the same cost for travel/transport, the SC formulation results in a saving on the costs incurred by the patient, especially indirect ones due to lost earnings, which are not reimbursed by social security bodies. … security bodies (included in the 245 working hours lost by the patient) ( Table 7 ). …

Sex differences in cancer incidence and survival: a Danish nationwide population-based study assessing 35 cancer sites.

BACKGROUND: Sex differences in cancer incidence and survival have been documented, but underlying mechanisms remain unclear. We examined sex differences in incidence and survival for non-sex-specific cancers and the role of socioeconomic factors and comorbidity. METHODS: All individuals living in Denmark from 2004-2020 were included. Incidence rate ratios (IRRs) and excess mortality ratios (EMRs) for 35 cancers were estimated using Poisson regression adjusted for age and year. Modification of associations between sex and death by cohabitation, education and comorbidity was assessed. RESULTS:

Decoding the Role of Companions in Supporting the Health Communication of Older African-American Men With Cancer.

The objective of this study was to systematically characterize the content and patterning of companion's communicative behavior during oncology consultations for older African-American male patients. Companions and family members often play an important role in patient-centered communication for patients with cancer. Despite their disproportionate cancer burden, little is known about how companions facilitate patient-provider communication for older African-American men with cancer. This study represents a secondary qualitative analysis of 14 video-recorded doctor patient-companion medical vis

Disability-Adjusted Life Years for Cancer in 2010⁻2014: A Regional Approach in Mexico.

The disability-adjusted life years (DALYs) were used to estimate the regional (state of Colima, Mexico) cancer burden in 2010⁻2014. The years of life lost (YLL) were estimated with mortality data and years lived with disability (YLD) using incidence data. The DALYs were calculated as the arithmetic addition of YLL and YLD. Sex and cancer site-specific estimations were made and DALY rates were used to identify the leading causes of disease burden. Data from 2532 deaths were analyzed and, for all malignant tumors combined, 18,712.9 DALYs and 20,243.3 DALYs were estimated in males and females res

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… A published research ranking the cancer burden among users from the Mexican Institute of Social Security (from Spanish Instituto Mexicano del Seguro Social ) had similar findings [ 22 ]. … The burden of disease of cancer in the Mexican Social Security Institute Salud Publica Mex. 2016 58 132 141 10.21149/spm.v58i2.7781 27557371 23. Castillejos-Molina R.A. Gabilondo-Navarro F.B. Prostate cancer Salud Publica Mex. 2016 58 279 284 10.21149/spm.v58i2.7797 27557386 24. …

Cancer during a pandemic: A psychosocial telehealth intervention for young adults.

The SARS-II COVID-19 pandemic has posed pronounced global health threats and prompted assorted transformations in societal engagement and clinical service delivery. For cancer survivors, many of whom are immune-compromised, these pandemic-related health threats pose greater challenges, warranting extra precautions within everyday living. Young adult (YA) cancer survivors already confront many unique physical and emotional challenges specific to their demographic. Already comfortable with assorted technologies, the pandemic presented an opportunity to provide telehealth intervention that target

Что имеет значение для пациентов с множественным склерозом? Определение параметров, имеющих отношение к пациентам, с использованием ранжирования с открытыми ответами по результатам онлайнового обследования в Италии.

ЦЕЛИ: Данное исследование было направлено на изучение того, какие особенности вмешательства или атрибуты вновь диагностированных лиц с множественным склерозом (МС) считаются важными, и изучение возможных причин, лежащих в основе их оценок. DESIGN: Поэтапный подход начался с систематического обзора литературы в целях выявления важных атрибутов. Пациенты, имеющие MS, затем оценивали эти атрибуты с помощью онлайнового обследования, которое включало в себя ранжирование и открытые вопросы. Наконец, результаты были оценены клинической группой для определения наиболее важных факторов индивидуального

Geriatric assessment for the practicing clinician: The why, what, and how.

Older adults with cancer heterogeneously experience health care, treatment, and symptoms. Geriatric assessment (GA) offers a comprehensive evaluation of an older individual's health status and can predict cancer-related outcomes in individuals with solid tumors and those with hematologic malignancies. In the last decade, randomized controlled trials have demonstrated the benefits of GA and GA management (GAM), which uses GA information to provide tailored intervention strategies to address GA impairments (e.g., implementing physical therapy for impaired physical function). Multiple phase 3 cli