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Hematology

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… Proceed to compression U/S or impedance plethysmography → serial studies → venogram APPROACH —“diagnostic accuracy for DVT improves when clinical probability is estimated before diagnostic tests. Patients with low clinical probability on the predictive rule have prevalence of DVT of <5%. … Proceed to compression U/S or impedance plethysmography → serial studies → venogram APPROACH —“diagnostic accuracy for DVT improves when clinical probability is estimated before diagnostic tests. Patients with low clinical probability on the predictive rule have prevalence of DVT of <5%. …

Effects of physical exercise in patients undergoing haematopoietic stem cell transplantation: systematic review and meta-analysis.

PurposeTo evaluate the effects of physical exercise on key clinical outcomes (such as quality of life (QoL), aerobic capacity, fatigue, and muscle strength) in patients undergoing haematopoietic stem cell transplantation.MethodsPRISMA systematic review and meta-analysis from inception to April 2025. PubMed, Embase, Cochrane Library, Web of Science and Scopus databases were searched for eligible studies. Methodological quality and risk of bias were evaluated with the Pedro scale and the Risk-Of-Bias Tool for randomized trials (ROB2.0) respectively.ResultsAn initial search retrieved 5217 article

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… al. 2003 Pilot RCT Multiple myeloma Autologous HSCT 55 Intervention group (14) Aerobic and resistance training 32 weeks 7 days a week Variably, the programme is home based Aerobic capacity (Modified Balke protocol) Strength (1RM) Fatigue (POMS) Sleep quality (Actigraph) Anthropometric measurements (plethysmography … | Multiple myeloma | Autologous HSCT | 55 | Intervention group (14) | Aerobic and resistance training | 32 weeks | 7 days a week | Variably, the programme is home based | Aerobic capacity (Modified Balke protocol) Strength (1RM) Fatigue (POMS) Sleep quality (Actigraph) Anthropometric measurements (plethysmography …

Epoetin-beta treatment in patients with cancer chemotherapy-induced anaemia: the impact of initial haemoglobin and target haemoglobin levels on survival, tumour progression and thromboembolic events.

BackgroundEpoetin-beta is used to treat patients with cancer undergoing chemotherapy to alleviate the symptoms of anaemia, reduce the risk of blood transfusions and improve quality of life (QoL).MethodsThis meta-analysis of all 12 randomised, controlled studies of epoetin-beta evaluated the impact of therapy at different Hb-initiation levels and to different target Hb levels on overall survival, tumour progression and thromboembolic events (TEE). An analysis of risk factors pre-disposing patients to TEEs under epoetin-beta therapy was also performed. A total of 2297 patients are included in th

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… Management by impedance plethysmography . …

Материалы ежегодной конференции Канадского общества респираторных терапевтов, май 8-10, 2025.

Мы рады представить ряд выдержек из работы ежегодной Конференции по ТРСК. состоявшемся в Оттаве, Онтарио, в мае 8 в адрес 10, 2025, эта конференция включала в себя темы, подготовленные отдельными лицами, имеющими опыт работы в различных областях практики дыхательной терапии. Как видно из следующих резюме, работа наших коллег 2025 :: акцентировали внимание на текущих исследовательских и практических нововведениях, осуществляемых РТ. Мы приложили все усилия для того, чтобы включить все выдержки, принятые Комитетом по программе до предельного срока публикации; вместе с тем просьба иметь в виду, ч

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… Melanie Kjarsgaard, MSc, RRT, CRE mkjarsga@stjoes.ca Background/Introduction: Traditional measurements of lung function such as spirometry, plethysmography and gas dilution provide an assessment of flow, volume and resistance, however, they require coordinated efforts between both the user and the … Respiratory Therapists are to perform full Pulmonary Function Testing to ATS criteria and examine the obtained FVL and body plethysmography Raw. …

Состав органа и его результаты и управление в области множественного склероза: обзор скрипта.

Справочная информация: Растет интерес к ожирению и его распространенности, результатам и управлению в отношении людей с множественным склерозом (МС). Индекс массы тела (ИОМ) является традиционным маркером ожирения в MS, в то время как состав тела, включая отдельные отсеки тканей тела (например, жир, кости и мышцы), часто не учитывается, несмотря на его актуальность. Цель: Настоящий описательный обзор a) подчеркивает использование и полезность рентгеновской рентгеновской усвоения двух источников энергии (DEXA) в качестве точного и надежного показателя состава тела; b) тематический анализ и обоб

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… Common 2C methods of measurement are hydrodensitometry, air displacement plethysmography, and hydrometry [ 20 ]. The three-compartment model (3C) incorporates an additional component by subdividing fat-free mass into bone mineral and lean soft tissue mass [ 20 ]. …

Opportunistic CT for Prediction of Adverse Postoperative Events in Patients with Spinal Metastases.

The purpose of this study was to assess the value of body composition measures obtained from opportunistic abdominal computed tomography (CT) in order to predict hospital length of stay (LOS), 30-day postoperative complications, and reoperations in patients undergoing surgery for spinal metastases. 196 patients underwent CT of the abdomen within three months of surgery for spinal metastases. Automated body composition segmentation and quantifications of the cross-sectional areas (CSA) of abdominal visceral and subcutaneous adipose tissue and abdominal skeletal muscle was performed. From this,

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… This was defined as any symptomatic pulmonary embolism or symptomatic distal or proximal deep vein thrombosis diagnosed within 30 days of the surgery, using the following diagnostic procedures: venography, impedance plethysmography, pulmonary arteriography, chest CT, ventilation-perfusion lung scan, …

The lung function score and its components as predictors of overall survival and chronic graft-vs-host disease after allogeneic stem cell transplantation.

AimTo retrospectively assess if the modified lung function score (LFS) and/or its components, forced expiratory volume within the first second (FEV1) and diffusion capacity for carbon monoxide corrected for hemoglobin level (cDLCO), predict overall survival (OS) and chronic graft-vs-host-disease (cGvHD).MethodsWe evaluated 241 patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT) at the University of Regensburg Transplant Center between June 1998 and July 2005 in relation to their LFS, FEV1 and cDLCO, before and after HSCT.ResultsDecreased OS after allo-HSCT was rel

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… PFT was performed in our center according to the guidelines of the European Respiratory Society using the MasterScreen Body (Viasys Health Care, Würzburg, Germany) including spirometry, body plethysmography, and diffusion capacity measurements using the single breath method. …

Sacubitril/Valsartan Ameliorates Crizotinib-Induced Cardiotoxicity in Mice.

BackgroundLung cancer is one of the major cause of death globally. Crizotinib is a first-line drug used in treating non-small-cell lung cancer (NSCLC). However, the pathophysiological mechanisms underlying its cardiotoxicity are unknown. This study investigated the mechanisms of crizotinib-induced cardiotoxicity and explored whether this toxicity can be prevented by the angiotensin receptor/neprilysin inhibitor sacubitril/valsartan.MethodsMale C57BL/6 mice were randomly divided into three groups: control, crizotinib (40 mg ⋅ kg - 1 ⋅ d - 1 for four weeks), and crizotinib + sacubitril/valsartan

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… was dissected after sacrifice for subsequent experiments. 2.2 BP Measurement in Mice Conscious animals were pre-warmed in a warm-up chamber at 36 °C–37 °C for 15 mins and their systolic, diastolic and mean arterial blood pressure (SBP, DBP and MBP, respectively) were recorded by using tail sleeve plethysmography …

Lymphangioleiomyomatosis and Pregnancy-Do We Have All the Answers for a Woman Who Desires to Conceive?-Literature Review.

Lymphangioleiomyomatosis (LAM) is a rare, progressive, and poor-prognosis systemic disorder that primarily affects women of reproductive age, with a higher prevalence among individuals of Caucasian origin. However, there are limited reliable data on the prevalence of LAM during pregnancy. The fulminant respiratory clinical presentation that often includes progressive dyspnea on exertion, cough, or hemoptysis, frequently complicated by pneumothorax, and the increased risk of spontaneous abortion due to increased estrogen and progesterone production during gestation, are arguments that most ofte

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… Plethysmography detects a residual volume exceeding 120% of the predicted value due to air trapping. The diffusing capacity of carbon monoxide across the alveolar-capillary membrane (DLCO) is frequently altered before the impairment of FEV1 [ 58 ]. …

Перепрофилированный активатор Nrf2 диметилфумарат спасает мышцы воспаление и фиброз в отягченной мышиной модели мышечной дистрофии Дученна.

В унаследованных нейромускульных болезнях мышечная дистрофия Дюченна (ДМД) глюкокортикоиды значительно медленнее прогрессируют, но в то же время создают достаточно серьезные побочные эффекты, исключающие применение в значительной части пациентов. Распространяя наши выводы о том, что в результате острого лечения с УЛХ были одобрены многочисленные склерозные препараты, диметилфумарат (ДМФ), спасающая мышечную патологию у молодых мышей Mdx, мы намеревались провести доклиническое тестирование на перевод. Чтобы усилить фенотип болезни у взрослых мышц mdx, у которых обычно нет эквивалентной человече

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… There was no effect of treatment on plethysmography (respiratory) readouts ( Supplemental Fig. 3E–G ) or kyphosis index ( Supplemental Fig. 3H–L ), albeit these measures were unaffected by mdx aggravation. …

Electroretinographic dysfunction, insulin resistance, and childhood trauma in early-course psychosis: A case-control exploratory study.

BACKGROUND: Subarachnoid hemorrhage (SAH) is characterized by intense central inflammation, leading to substantial post-hemorrhagic complications such as vasospasm and delayed cerebral ischemia. Given the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation (taVNS) and its ability to promote brain plasticity, taVNS has emerged as a promising therapeutic option for SAH patients. However, the effects of taVNS on cardiovascular dynamics in critically ill patients, like those with SAH, have not yet been investigated. Given the association between cardiac complications and e

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… We subsequently compared the plethysmography peripheral perfusion index (PPI) between the treatment groups as it is a proxy metric for cardiac stroke volume and vascular tone ( Elshal et al., 2021 ; Coutrot et al., 2021 ). …

Evaluation of the Enhanced Recovery After Surgery (ERAS) Guidance for Patients With Spinal Metastasis.

Surgery continues to remain the most effective treatment for spinal metastasis (SM). As the number of surgeries continues to grow, the need for consensus guidelines for optimal perioperative care is imperative. Enhanced recovery after surgery (ERAS) protocols were created for this purpose. The objective of this study is to review evidence-based ERAS guidelines for SM surgery. A group of multiple experienced spine surgeons was invited to participate in this study. This group identified 19 ERAS items for SM surgery. The principal literature search utilized MEDLINE, Embase, and Cochrane databases

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… Such as plethysmography variability index, perfusion index, mean arterial pressure, heart rate are important detection indicators of GDFM. Although different GDFM clinical trials had different clinical outcomes in promoting early postoperative rehabilitation [ 90 , 91 ]. …

Overview of Ayurveda and Ashwagandha: Bioactive Phytochemicals and Potential Applications to Gliomas.

Ayurveda is the traditional medical system of India and has been in use for more than 5000 years. The focus of Ayurveda is to maintain harmony and balance of the three Doshas (Vata, Pitta, Kapha), or life forces, that govern the physiology and health of each individual. Ashwagandha is considered one of the most useful plants in the Ayurvedic system for various illnesses, including cancer. Ethnopharmacological and phytochemical analyses have been elucidating the bioactive compounds in ashwagandha that mediate the anti-cancer effects. The most bioactive compounds appear to be the withanolides, i

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… Some older methods, such as pulse diagnosis and plethysmography, have been shown to be too subjective, with poor inter-rater reliability. Various types of detailed questionnaires seem to be the most accurate and reliable method of determining Prakriti at the moment, but more research is needed. …

Whole body vibration training during allogeneic hematopoietic cell transplantation-the effects on patients' physical capacity.

Patients undergoing allogeneic hematopoietic cell transplantation (alloHCT) experience a considerable decline in physical and psycho-social capacity. Since whole body vibration (WBV) is known to efficiently stimulate the neuromuscular system and enhance cardiorespiratory fitness and muscle strength in frail individuals, we hypothesized that WBV would maintain various physical and psychological capacities in patients during alloHCT. Seventy-one patients were randomly allocated to either an intervention group (IG) doing WBV or an active control group (CG) doing mobilization exercises five times

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… Body composition To determine body fat (%; kg) and fat-free mass (%), an air displacement plethysmography system (Bod Pod Body, Composition System, Life Measurement, INC) as well as bioelectrical impedance analysis (BIA, Nutriguard-S, Data Input, Pöcking, Germany) was used. …

European Guidelines for Obesity Management in Adults.

Obesity is a chronic metabolic disease characterised by an increase of body fat stores. It is a gateway to ill health, and it has become one of the leading causes of disability and death, affecting not only adults but also children and adolescents worldwide. In clinical practice, the body fatness is estimated by BMI, and the accumulation of intra-abdominal fat (marker for higher metabolic and cardiovascular disease risk) can be assessed by waist circumference. Complex interactions between biological, behavioural, social and environmental factors are involved in regulation of energy balance and

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… With the development of devices and equipment to more accurately measure body fat, including dual energy X-ray absorptiometry (DEXA), air-displacement plethysmography (BodPod), bioimpedance analysis (BIA) and body scanning procedures – replacing the cumbersome underwater weighing -, it has become possible …

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: children and adolescents.

The Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Children and Adolescents was developed by dietitians, physicians, and pediatric hematologists from 10 Brazilian reference centers in hematopoietic stem cell transplantation. The aim was to emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to patient´s nutritional assessment. This consensus is intended to improve and standardize nutrition therapy during hematopoietic stem cell transplantation. The consensus was approved by the Brazilian

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… There are several methods to assess body composition, such as waist circumference and skin folds, magnetic resonance, computed tomography, body densitometry, ultrasound, bioimpedance analysis, total body potassium and air plethysmography. ( 29 – 31 ) In pediatrics, and in association with allogeneic …

Машинное обучение выявляет микробиомы и клинические прогнозы устойчивой потери веса после продолжительного поста.

Длительное постирование может улучшить метаболическое здоровье, однако контролируемые данные по здоровым взрослым с более длительным последующим наблюдением и многомерным профилированием ограничены. Мы расследовали немедленное и 12-week ПОСЛЕДУЮЩИЕ ПОСЛЕДУЮЩИЕ ПОСЛЕДСТВИЯ 5-day Быстрое вмешательство в состав тела, кишечный микробиом и циркулирующие и фекальные метаболиты, а также оценка того, прогнозируют ли базовые характеристики индивидуальные реакции на потерю веса. В ходе случайного, контролируемого списка ожидания, 38 здоровые взрослые 5-day быстрого вмешательства с помощью 12-week :: пос

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… We measured waist and hip circumference to calculate waist-to-hip ratio and determined body composition (lean and fat mass) by air displacement plethysmography (Bod Pod, Life Measurements, Inc., Concord, CA). …

Antiobesity Medications for Older Adults-the New, the Good, the Bad, and the Unknown.

OBJECTIVE: Obesity affects 42% of older adults, with rates continuing to rise. This a complex condition influenced by non-modifiable as well as modifiable risk factors. The disease can be treated through modifications to diet, physical activity, and behavior and more recently through antiobesity medications (AOMs) and surgery. Treatment must be tailored to individual needs due to age-related metabolic and physiological changes. This review aimed to identify the suitability of seven FDA-approved AOMs in the treatment of obesity in older adults. METHODS: A review of AOMs was performed, focusing

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… In this trial, VBC measurement of body fat was compared to professional bioimpedance systems and air displacement plethysmography, and VBC performance was superior to these other methods. …

Respiratory and Thoracic Medicine

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37th International Symposium on Intensive Care and Emergency Medicine (part 1 of 3) : Brussels, Belgium. 21–24 March 2017

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