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Dermatologic conditions in women receiving systemic cancer therapy.

As advances in cancer therapies have improved cancer-related survival, novel therapeutics have also introduced a variety of dermatologic toxicities, and an increased number of patients are living with these sequalae. Women with cancer in particular experience a spectrum of dermatologic conditions that affect their skin, hair, nail, and mucosal surfaces. Studies have shown that these toxic effects can significantly affect quality of life and alter a woman's self-image, cultural identity, femininity, sexuality, and mental health. In severe instances, dermatologic toxicities may even disrupt canc

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… Winther et al. (2007) found that 40% of patients with docetaxel-induced nail changes had functional problems, 37% had trouble finding comfortable shoes, and 33% had difficulty ambulating. … Prevention and treatment Preventive measures focus on minimizing friction to vulnerable areas by wearing supportive socks (e.g., running socks), gel inserts, and soft shoes; avoiding mechanical irritation of the hands; and avoiding temperature extremes ( Chu et al., 2008 ). …

Minimally Invasive Chevron Akin Osteotomy for Hallux Valgus Correction.

BACKGROUND: The minimally invasive chevron Akin osteotomy technique is indicated for the treatment of symptomatic mild to moderate hallux valgus deformities. The aim of the procedure is to restore alignment of the first ray while minimizing soft-tissue disruption. DESCRIPTION: Prior to the procedure, radiographs are utilized to characterize the patient's hallux valgus deformity by determining the hallux valgus angle and intermetatarsal angle. The metatarsal rotation is also assessed via the lateral round sign and sesamoid view. To begin, a stab incision is made over the lateral aspect of the

Validation of the Artificial Floor Technique in First Metatarsophalangeal Joint Arthrodesis.

BACKGROUND: Patient function after arthrodesis of the first metatarsophalangeal joint (MTPJ) relies on proper positioning of the first MTPJ. To maximize the likelihood of good postoperative function, the dorsiflexion angle, referred to as the fusion sagittal angle, should range between 20° and 30°, corresponding to 10° to 15° of dorsiflexion off the weightbearing axis. However, achieving appropriate sagittal alignment intraoperatively is challenging. The artificial floor technique (AFT) uses a rigid, flat surface to simulate the weightbearing position of the foot intraoperatively to accurately

Operative treatment of displaced intraarticular calcaneal fractures: long-term (10-20 Years) results in 108 fractures using a prognostic CT classification.

OBJECTIVE: The primary purpose of this study was to determine whether the Sanders computed tomography (CT) scan classification was still prognostic for outcome when long-term (10-20 years) radiographic and functional data of patients after open reduction and internal fixation for Sanders type II versus type III displaced intra-articular calcaneal fractures (DIACFs) were compared. The secondary purpose was to assess whether a bone graft or a locked plate was needed to maintain a reduction over time. DESIGN: Prognostic case-control study. SETTING: Level I trauma hospital. PATIENTS: Patients w

Экспериментальное технико-экономическое обоснование исследования виртуальной оценки гейт на основе реальности с орехами у людей с множественным склерозом: исследовательский протокол.

Множественный склероз (МС) часто приводит к значительным нарушениям в походах и мобильности. Несмотря на то, что пешие брекеты обычно предписываются, их эффективность в реальном мире ограничивается недостаточной адаптацией. Традиционные клинические оценки основываются на субъективных масштабах и могут не в полной мере отражать проблемы повседневной жизни. Неизмеримая виртуальная реальность (VR) и износимые сенсоры предлагают перспективные решения для экологического мониторинга, однако их комбинированное использование по-прежнему не является приемлемым для ортопедической поддержки в MS. В рамка

Primary Angiosarcoma of Humerus - A Case Report and Literature Review.

INTRODUCTION: When the fracture fails to heal for more than 12 months, it is called chronic non-union. Surgical intervention becomes mandatory to get this type of fracture healed. We are reporting our results in a case of congenital pseudoarthrosis of the tibia (CPT) having chronic non-union of 18 years duration with superadded infection following attempted surgery, using Ilizarov technology. We shall highlight the problems found during the course of treatment and different strategies to tackle them. CASE PRESENTATION: An 18-year-old female, born with CPT of the right tibia with neurofibromat

'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives.

ObjectivesTo explore alignment of experiences before lymphoma and myeloma diagnosis with the appraisal, help seeking and diagnostic intervals in the Model of Pathways to Treatment (MPT).DesignA qualitative study using in-depth semistructured interviews with patients and relatives. Interviews were transcribed verbatim, anonymised and analysed using qualitative description.SettingA UK population-based haematological malignancy patient cohort.ParticipantsFifty-five patients (35 lymphoma, 20 myeloma: diagnosed 2014-2016) and 28 relatives participated, within around a year of the patient's diagnosi

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… Some relatives said they adapted their own behaviour to accord with the patient, often over long time periods: ‘patient’s) height loss, was gradual, at first, so, I noticed…I stopped buying shoes with heels, because I was getting to be, you know, too tall (for him) when I was wearing shoes with heels …

Through the Eyes of Patients: The Effect of Training General Practitioners and Nurses on Perceived Shared Decision-Making Support.

PurposeTo examine the effects of training general practitioners and nurses in shared decision-making (SDM) support as perceived by cancer patients and survivors.DesignAn innovative, experimental design was adopted that included analogue patients (APs), that is, people who have or have had cancer and who imagine themselves in the position of the actor-patient presented in a video. Each AP assessed a video-recorded simulated consultation of a health care professional (HCP) conducted before or after an SDM support training program. The primary outcome was the APs' perceived SDM support with 13 se

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… APs were explicitly asked to not only observe but also sympathize with the actor-patient, that is, to put oneself in the shoes of the patient while watching the video recording and to pay particular attention to how the HCP and patient talked about the treatment decision. … Can naive patients put themselves in patients’s shoes? Reliability and validity of the analogue patient methodology. Med Care. 2013;51:e16–21. 28. van Vliet LM, van der Wall E, Albada A, Spreeuwenberg PM, Verheul W, Bensing JM. …

Impact of discontinuing 5 years of enzyme replacement treatment in a cohort of 6 adults with hypophosphatasia: A case series.

Asfotase alfa is a human recombinant enzyme replacement therapy for hypophosphatasia. We describe 6 adults who were treated with asfotase alfa for 61-68 months in a clinical trial (NCT01163149), after which asfotase alfa was discontinued for 15-48 months. The patients experienced clinical deterioration and, when treatment was restarted, showed improvement. Patients with hypophosphatasia should be closely monitored if asfotase alfa is stopped as clinical decline is likely. Clinical practice guidelines are needed.

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… , codeine, ibuprofen, naproxen | Not available Use of assistive devices Prior to restarting ERT | Cane, walker, modification to bath/shower, long-handled appliances | Not available | Cane, special or built-up chair, modification to toilet/bath/shower, long-handled appliances | None used | Orthotic shoes … , jar opener | Cane, table, props, modification to bath/shower Most recent follow-up | Walker, cane, modification to bath/shower, jar opener, long-handled appliances | Not available | Cane, special or built-up chair, modification to toilet/bath/shower, long-handled appliances | None used | Orthotic shoes …

Association between nutritional status and biochemical markers among hematopoietic stem cell transplant candidates: a cross-sectional study.

AimCandidates of Hematopoietic Stem Cell Transplantation (HSCT) may be at nutritional risk due to decreased oral intake, high nutritional requirements and nutrient malabsorption. The aim of this study was to evaluate the association between nutritional status and blood biomarkers in candidates of HSCT.MethodsA total of 278 patients aged 18-65 years old were recruited and their baseline demographic and clinical characteristics were recorded. All subjects underwent nutritional status analysis using Nutritional Risk Screening (NRS-2002). Blood biomarkers including C-reactive protein (CRP), Erythr

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… Weight was measured with minimal clothing and without shoes with 0.1 kg accuracy. Standing height of the patients was measured without shoes with 0.1 cm accuracy (Balas Company, Iran). Body Mass Index (BMI) was calculated by dividing the weight (kg) by height squared (m 2 ). …

Chemical-specific health consultation for chromated copper arsenate chemical mixture: port of Djibouti.

The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public h … anner approved for pesticide disposal. Workers should leave all protective clothing, including work shoes and boots, at the workplace, so that CCA will not be carried into their cars and homes, which would endanger other people. People not involved in the cleanup of the CCA and who are not wearing protective clothing should be prevented from entering co …

The effect of oral nutrition supplement (ONS) on the nutritional and clinical status of patients undergoing autologous hematopoietic stem cell transplantation: study protocol for a randomized controlled clinical trial.

IntroductionSeveral side effects within the patients undergoing hematopoietic stem cell transplantation (HSCT), especially ones that influence nutrition intake, can cause weight loss and malnutrition. Based on studies, oral nutritional supplement (ONS) may reinforce their nutrient intake and progress clinical outcomes. The objective of this research is to investigate the effect of oral nutrition supplements on the nutritional and clinical status of patients undergoing autologous hematopoietic stem cell transplantation.MethodsAfter block randomization used the website www.randomization , 38 pat

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… Digital scales (Seca, Hamburg, Germany) will be used to measure body weight in a fasting state, without shoes, with minimal clothing, to the nearest 100 g. Standing height will be measured using a tape measure mounted on the wall without shoes with an accuracy of 0.5 cm. …

Surgical interventions for treating hallux valgus and bunions.

BACKGROUND: Hallux valgus (lateral angulation of the great toe towards the lesser toes, commonly known as bunions) presents in 23% to 35% of the population. This condition leads to poor balance and increases the risk of falling, adding to the difficulty in fitting into shoes and pain. Conservative (non-surgical) interventions treating pain rather than curing deformity are usually first-line treatments. When surgery is indicated, the overall best surgical procedure is an ever-evolving topic of discussion. OBJECTIVES: To assess the benefits and harms of different types of surgery compared with …

Lifestyle in Multiple Myeloma - a longitudinal cohort study protocol.

BACKGROUND: Deterioration in bone health is one of the presenting symptoms of Multiple Myeloma (MM), a cancer of plasma cells. As a consequence of this condition, patients suffer bone pain and bone damage and report cancer-related fatigue, resulting in deterioration in their quality of life. Evidence in patients with solid tumours shows promise for the positive effects of physical activity on quality of life. However, in the case of patients with MM a better understanding of the association between physical fitness and quality of life factors is still required. Therefore, this cohort study aim

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… Height without shoes is measured using a Leicester height measure and body mass index (BMI) calculated (weight kg/height 2 ). …

Цифровой дистанционный мониторинг людей с множественным склерозом.

ВВЕДЕНИЕ: Множественный склероз (MS) является хроническим нейродегенеративным заболеванием, которое затрагивает более 2,8 млн. человек во всем мире и приводит к значительным симптомам моторного и немоторного происхождения. Эффективный мониторинг заболеваний имеет решающее значение для улучшения результатов лечения пациентов, но часто затрудняется ограниченностью редких клинических оценок. Цифровые средства дистанционного мониторинга с использованием больших данных, и МА открывает новые возможности для отслеживания симптомов в режиме реального времени и выявления развития заболеваний. МЕТОДЫ: В

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… However, one key limitation is the compatibility of insoles with different shoe types, and the need to switch the insoles when changing shoes and when recharging, which could prove burdensome for patients in the long term, and could lead to missing data for extended periods of time or in some specific …

Case series: Odontohypophosphatasia or missed diagnosis of childhood/adult-onset hypophosphatasia? - Call for a long-term follow-up of premature loss of primary teeth.

IntroductionHypophosphatasia, a metabolic bone disease caused by a tissue-nonspecific alkaline phosphatase deficiency, leads to undermineralization of bone and/or teeth, impaired vitamin B6 metabolism, and a spectrum of disease presentation. At the mild end of the spectrum, it presents as pathologic fractures in later adulthood. Patients with isolated dental manifestations, typically presenting as premature loss of primary teeth, are classified as having odontohypophosphatasia (odontoHPP). A subset of patients diagnosed with odontoHPP in childhood can later develop extra-dental manifestations

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… Case 7 This is a 50-year-old woman who had missing teeth and premature primary tooth loss, developed chronic joint pain and required orthopedic shoes in childhood, and developed 19 fractures starting at age 18. …

Воздействие вицеральной ожирения на клинический исход и качество жизни пациентов с множественной миеломой: вторичный анализ данных о СТАМИНЕ (BMT CTN) 0702) Судебное разбирательство

Краткое изложение проблемы ожирения является общей проблемой для здоровья многих пациентов, страдающих миеломой (ММ), и она связана с плохими клиническими результатами и качеством жизни (КОЛ). Мы провели вторичный анализ БМТ CTN 0702, выборочное, контролируемое испытание с сопоставлением результатов three :: лечение после одной пересадки гематополиетических клеток (ГХТ) для изучения воздействия висцерального ожирения, измеряемого соотношением талии и голени (ВПЧ), на клинические результаты и QOL у пациентов с MM. 549 Пациенты ММ, средний возраст 55.5 Годы, были зачислены в исследование. Больши

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… Height and weight were measured without shoes and in light clothing or hospital gown. Self-reported height was acceptable only if the patient was unable to stand. Waist and hip measurements were taken in underwear or with light clothing or hospital gown and were recorded in centimeters. …

Oncology Nursing During a Pandemic: Critical Reflections in the Context of COVID-19.

ObjectivesTo provide a critical reflection of COVID-19 in the context of oncology nursing and provide recommendations for caring for people affected by cancer during this pandemic.Data sourcesElectronic databases, including CINAHL, MEDLINE, PsychINFO, Scopus, professional web sites, and grey literature were searched using Google Scholar.ConclusionNurses are key stakeholders in developing and implementing policies regarding standards of care during the COVID-19 pandemic. This pandemic poses several challenges for oncology services. Oncology nurses are providing a pivotal role in the care and ma

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… PAPRs) Eye protection | Mask with eye protection or goggles if splashing is likely and for cleaning of spills | Full face piece air purifying respirators or PAPRs Gloves | Double chemotherapy-tested gloves | Single chemotherapy-tested gloves, double standard exam gloves, or single standard exam glove Shoe … covers | Use in compounding areas only | Work-only washable shoes Safe handling of NIOSH drugs | Poly-coated gown and double chemotherapy tested gloves (single use to hang or take down chemotherapy) | Use one gown per patient – hang gown inside-out near patient and away from surfaces between uses One …

Важное значение акромагалоидных физических свойств для клинической практики.

Акромагали и гигантизм - это гормональные расстройства, которые возникают в результате гиперсекретирования хронического роста гормона. Псевдоним префикса используется для описания определенного клинического состояния без четко подтвержденной характеристики патофизиологического механизма и основных биохимических характеристик; псевдоакромегалы или акромигалоидизм соответствуют определению, приведенному выше. В данном случае мы попытаемся представить краткий обзор диагностической оценки акромигалоидной физической внешности при обсуждении two - случаи пациентов, которые имеют такие же клинические

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… In the mentioned period, he also noticed enlargement of his hands and feet with an increase in shoes size for 2 numbers. The patient denied headache and visual problems. A clinical examination revealed coarse face, deep creases on his forehead, broad nose, and bilateral conjunctivitis. …

Средиземноморская диета и достаточность питательных микроэлементов в связи с риском повторного возникновения множественных склерозов: тематическое исследование.

Множественный склероз (MS) является хроническим аутоиммунным и нейродегенеративным заболеванием, под влиянием экологических факторов, включая рацион питания. Средиземное питание (MeDi), богатое антивоспалительными и антиокислительными соединениями, а также адекватность питательных микроэлементов могут снизить риск и прогрессировать в плане НР. АИМ: Цель настоящего исследования заключается в изучении связей между Средиземноморским диетическим счётом (MDS), средним коэффициентом достаточности (MAR) и риском, связанным с НР, в рамках контроля за конкретными случаями. МЕТОДЫ: Это тематическое иссл

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… Weight and body composition were assessed using a body impedance analyzer (Tanita BC‐418) for each included individual when they were without shoes and wearing minimal clothes. …