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Thai Osteoporosis Foundation (TOPF) position statements on management of osteoporosis.

The adjusted incidence rate of hip fracture in Thailand has increased more than 31% from 1997 to 2006. Mortality and morbidity after hip fracture are also high. One year mortality after a hip fracture has increased from 18% in 1999 to 21% in 2007. The Thai Osteoporosis Foundation (TOPF) developed the first Clinical Practice Guideline (CPG) in 2002 and keeps updating the CPG since then. This latest version of the CPG is our attempt to provide comprehensive positional statement on the diagnosis, prevention and treatment of osteoporosis in Thailand. The study group who revised this position state

Risk of Surgeon Contracting COVID-19 while Operating on COVID-19-Positive Patient, Impact of Safety Measures: Lessons Learnt.

Introduction  On March 11, 2020, the novel coronavirus disease 2019 (COVID-19) was declared as a pandemic. General surgeons provide care to COVID-19 positive patients requiring emergency surgeries and hence are exposed to the virus. Surgery on COVID-19-positive patient itself is a major risk factor for surgeon to contract COVID-19 infection. Noticeably, there is no data regarding number of surgeons who have contracted COVID-19 after operating on COVID-19-positive patients. Hence, the aim of this study was to find out the exact incidence of COVID-19 among surgeons operating on COVID-19-positive

Interventions for preventing falls in older people living in the community.

BACKGROUND: Approximately 30% of people over 65 years of age living in the community fall each year. This is an update of a Cochrane review first published in 2009. OBJECTIVES: To assess the effects of interventions designed to reduce the incidence of falls in older people living in the community. SEARCH METHODS: We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (February 2012), CENTRAL (The Cochrane Library 2012, Issue 3), MEDLINE (1946 to March 2012), EMBASE (1947 to March 2012), CINAHL (1982 to February 2012), and online trial registers. SELECTION CRITERIA

Машинное прогнозирование качества сна у пациентов с множественным склерозом.

Предыстория/задачи: нарушения сна являются распространенными, но часто недооцениваются при множественном склерозе (МС), независимо предсказывая снижение качества жизни и усиливая усталость, когнитивное расстройство и депрессию. В то время как боль, ноктура, усталость и симптомы настроения являются известными причинами, кардиометаболические и подстрекательские факторы остаются в основном неизученными, несмотря на их известные связи с плохим сном в других группах населения. В этом исследовании используется интерпретируемое машинное обучение для определения относительного вклада связанных с болез

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… Anthropometric and hemodynamic measurements: Body weight was measured using a calibrated mechanical scale, and height using a stadiometer, with participants in light clothing and without shoes; BMI was calculated as weight (kg)/height 2 (m 2 ). …

'It gives you an understanding you can't get from any book.' The relationship between medical students' and doctors' personal illness experiences and their performance: a qualitative and quantitative study.

BackgroundAnecdotes abound about doctors' personal illness experiences and the effect they have on their empathy and care of patients. We formally investigated the relationship between doctors' and medical students' personal illness experiences, their examination results, preparedness for clinical practice, learning and professional attitudes and behaviour towards patients.MethodsNewly-qualified UK doctors in 2005 (n = 2062/4784), and two cohorts of students at one London medical school (n = 640/749) participated in the quantitative arm of the study. 37 Consultants, 1 Specialist Registrar, 2 C

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… I guess being able to put yourself in other people's shoes." [Teacher 5, male, Consultant Physician] "A sprinkling of graduate students helps learning: they have more life experience, what the GMC [General Medical Council] would call 'transferable skills'." …

Оценка понижательного риска при множественном склерозе с использованием результатов, о которых сообщают пациенты, и износимых показателей походок.

Падение людей с множественным склерозом (pwMS) ведет к заболеваемости и расходам. ЦЕЛЬ: Определение клинических параметров, связанных с водопадами. МЕТОДЫ: Eighty-six PCMS завершены обследования осенних осадков, времяd 25-foot Пройдите (T25FW) и анализ движения с помощью устройств Clario Opal. Были разработаны модели логистической регрессии. Результаты: Средний возраст 54.5 годы (дальность 21-73), 62% (В тыс.53) были женщинами. Включена группа 58% с вращением50) и 42% с прогрессивным НР36). Лица, сообщившие о сокращении в прошлом году, были старше (средний возраст) 58 vs. 52.5, р = .03) и имел

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… Gait assessment Participants completed two trials of a timed 25-foot walk (T25FW) assessment with patients instructed to walk at their natural pace in comfortable shoes. The fastest of the two trials was analyzed. …

Sphingobacterium multivorum cellulitis: case report and mini-review.

BACKGROUND: Sphingobacterium multivorum is a gram-negative, non-fermentative, oxidase-positive, catalase-positive bacillus. S multivorum has been identified in urinary tract infections, respiratory tract infections, spontaneous peritonitis, septic arthritis, meningitis, bacteraemia and septic shock. Ours is the second case of skin and soft tissue infection sustained by S. multivorum (a case of necrotizing fasciitis with septic shock has been previously reported). In this paper, we furnish a review of the literature on all the cases of S multivorum described in the medical literature (with the

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… Wearing protective equipment adapted to the activities (gloves, shoes, and clothing), regular maintenance of the environment of the accommodation premises, and respect for hygiene recommendations during medical procedures should make it possible to avoid such infections. …

Economic Burden of Intravenous Decitabine Administration in Patients Affected by Acute Myeloid Leukemia Ineligible for Induction Chemotherapy and Impact of Oral Formulation Introduction: A Micro-Costing Study in Italy.

PurposeIntravenous (IV) decitabine is a therapeutic option for patients with newly diagnosed acute myeloid leukemia (AML) ineligible for induction chemotherapy. Recently, the oral formulation of decitabine-cedazuridine demonstrated comparable efficacy and safety to IV decitabine, and pharmacokinetic equivalence. This study estimates the direct non-drug healthcare costs of IV decitabine administration in Italy, including central venous catheter (CVC) and infection management, and assesses the economic impact of oral decitabine introduction.MethodsA micro-costing analysis from the Italian Nation

Primary hyperhidrosis: an updated review.

BACKGROUND: Hyperhidrosis (HH) is a condition characterized by excessive sweating beyond the physiological needs of thermoregulation. HH can be classified as primary (idiopathic) hyperhidrosis (PHH) or secondary hyperhidrosis (SHH), which is associated with underlying medical conditions, medications or systemic disorders. This narrative review provides an updated overview of PHH, with a focus on epidemiology, aetiopathogenesis, clinical manifestations, diagnostic approaches and current management strategies, particularly highlighting pharmacological and procedural treatment options. METHODS:

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… triggering emotional stimulation. 114 Adjunctive therapies that fall into this category include using moisture-wicking sheets and pyjamas, portable body coolers, pens that can write in wet conditions, shirts with cooling devices, synthetic fabrics, masking sweat with underarm liners, dress shields, leather shoes … , absorbent shoe insoles, foot powder and cotton/wool socks. 114 , 115 , 200 , 201 Lifestyle, behavioural and adjunctive therapies are recommended for all patients with PHH regardless of the type, can be initiated at any time, and are often used in conjunction with another treatment modality to support …

Profile of elderly patients receiving antiretroviral therapy at Newlands Clinic in 2020: A cross-sectional study.

BACKGROUND: People living with HIV (PLWH) face new challenges such as accelerated ageing and higher rates of comorbidities including cardiovascular, renal and metabolic diseases as they age. OBJECTIVES: To profile the demographic and clinical characteristics of elderly patients receiving HIV care at Newlands Clinic (NC), Harare, Zimbabwe, as of 01 October 2019. METHODS: A cross-sectional analysis was conducted using clinic data. All patients who were 50 years and older on 01 October 2019 were enrolled. Descriptive statistics (medians, interquartile ranges [IQRs] and proportions) were used to

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… Before being weighed, patients removed shoes, jackets and emptied their pockets. Samples for blood glucose measurement were collected into 4-mL BD Vacutainer Plus plastic tubes with 10 mg sodium fluoride and 8 mg potassium oxalate additives. …

Treatment of metastatic lesions localized in the acetabulum.

BackgroundMetastatic lesions localized in the periacetabular area cause troublesome pain and reduced mobility of the patients. Radiotherapy effectively decreases pain, yet it does not restore the ability to load the joint. Surgical treatment involving resection of metastatic lesions and joint reconstruction using bone grafts is burdened with a high rate of complications. Modular tumor prostheses are being increasingly used. In some cases, it is possible to strengthen the acetabular roof with bone cement using vertebroplasty kits. The aim of the study was to demonstrate various methods of treat

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… It was compensated using insoles for shoes. Results of the treatment of bone losses in the pelvis with bone cement (PMMA) using vertebroplasty kits are very encouraging. No inflammatory reactions in soft tissues after precutaneous injection of cement were noted. …

How do Internal Medicine Residents from Different Backgrounds Make Subspecialty Career Choices? A Qualitative Analysis.

PurposeMedical career decisions are complex. Gender and racial disparities remain among internal medicine (IM) subspecialty fellows, particularly in procedural subspecialties. This qualitative study aims to thematically explore factors that influence IM resident subspecialty career choice, with a focus on factors specific to women and UIM trainees to better understand existing disparities. This is the first study to explore IM residents own stated reasons to subspecialize into various fields.MethodsWe conducted virtual focus groups with 37 IM residents from multiple institutions, organized by

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… shared a lot of similarities with [my research mentors], whether it's race or growing up in a similar part of the country or going to the same med [school] […] In the process as I was seeking out mentors, whether consciously or subconsciously, I realized I wanted to be able to see myself […] in their shoes …

Duke Cancer Care Experience: a longitudinal, multidisciplinary oncology curriculum for medical students.

BackgroundCancer prevalence continues to rise in the United States with a projected shortage of oncologists in the workforce. Despite this need, medical schools often lack oncology-focused education in their curriculum. Duke's Cancer Care Experience (CCE) is a multi-disciplinary elective designed to meet the growing demand for highly competent, compassionate, and diverse physicians of all medical specialties who are aware of the unique needs of patients diagnosed with cancer. CCE integrates principles of adult learning theory to increase learner engagement and prioritize knowledge retention of

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… There was a modest increase in the percentage of those who agreed or completely agreed with the following statements: "when I’m upset at someone, I usually try to “put myself in their shoes” for a while" (2023: pre 85%, post 93%, 2024: pre 81%, post 91%), "before criticizing somebody, I try to imagine …

Impact of stress and coping strategies on quality of life in hematological malignancies: A cross-sectional study.

Background and aimsWhile perceived stress and coping strategies have been established as significant determinants of quality of life (QoL) in patients with solid malignancies, their impact on hematological malignancy population have not been fully elucidated. This study aimed to examine how perceived stress and medical coping strategies interact with sociodemographic factors to influence QoL in patients with hematologic malignancies.MethodsThe study, involving 185 hematologic cancer patients in China, was conducted between August 2024 and December 2024. Self-reported scales were used to assess

Occupational risk factors among Iranian farmworkers: a review of the available evidence.

Farming is one of the most important components of most economies. No comprehensive picture exists of the health status of Iranian farmers and the work-related hazards that affect them. We aimed to determine the gaps in the current knowledge regarding the occupational health of Iranian farmworkers. Electronic databases including Medline, Web of Science, Scopus, and Embase, as well as national databases including the Scientific Information Database, MagIran, and Barakat Knowledge System, were searched for articles published through March 2017. All epidemiologic studies regarding the occupationa

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… C. parvum was identified in 72% of the positive farm workers and 65% of the positive household members Contact with calves (p<0.0001) was an important risk factor of C. parvum infection A negative association was observed between C parvum infection and cleaning of shoes/boots after daily work (p=0.004 …

Clinical curative effect and quality of life evaluation of dupilumab in treating children with atopic dermatitis and its effect on IgE levels, eosinophil count, Th2 cytokines (IL-4 and IL-13), and thymus and activation-regulated chemokine.

INTRODUCTION: Atopic dermatitis (AD) is a common chronic skin inflammatory disease. The traditional treatment shows limited effect and side effects. Dupilumab is a monoclonal antibody immunotherapy targeting IL-4 and IL-13, which may become a new direction for treating AD. AIM: This study was to explore the clinical curative effect of dupilumab in the treatment of children with AD, and its influence on the quality of life (QoL) of children. MATERIAL AND METHODS: 54 children with AD, who were treated in the outpatient and inpatient departments of the hospital from August 2023 to July 2024, we

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… | 0 | 1 | 2 | 3 How much have your skin lesions influenced your choice of clothes and shoes? | 0 | 1 | 2 | 3 How much have your skin lesions impacted your social or leisure activities? | 0 | 1 | 2 | 3 To what extent did your skin lesions make physical activities difficult? …

Interrupted Identities: Autologous Stem Cell Transplant in Patients With Multiple Myeloma.

In the current study, we sought to examine whether patients incorporate the identity of a patient receiving autologous stem cell transplant (ASCT) for multiple myeloma (MM) into their daily lives. Multiple myeloma patients receive education before initiating the ASCT treatment process. In this ethnographic study using interpretative phenomenological analysis, we observed pretransplant education visits with 30 MM patients, followed by semistructured interviews in their hospital rooms during transplant. The experience of receiving ASCT for MM required effort by patients to not only maintain thei

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… Susan, a 71-year-old retired white female, came to her evaluation day visit in attire she described as “glamorous”, as described in the following field note excerpt: “She wore a white, quarter length shirt with lace around her shoulder, black capris, and open toed shoes that revealed her freshly painted …

Influence of taste disorders on dietary behaviors in cancer patients under chemotherapy.

ObjectivesTo determine the relationship between energy and nutrient consumption with chemosensory changes in cancer patients under chemotherapy.MethodsWe carried out a cross-sectional study, enrolling 60 subjects. Cases were defined as patients with cancer diagnosis after their second chemotherapy cycle (n = 30), and controls were subjects without cancer (n = 30). Subjective changes of taste during treatment were assessed. Food consumption habits were obtained with a food frequency questionnaire validated for Mexican population. Five different concentrations of three basic flavors --sweet (suc

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… Physical exam Body weight was measured in light clothing and without shoes, to the nearest 0.10 kg. Height was measured to the nearest 0.5 cm. Body mass index (BMI) was calculated in all subjects. …

Exploring social determinants of health on chemotherapy-induced peripheral neuropathy severity in ovarian cancer: An integrative review.

Ovarian cancer remains a significant public health concern for women despite advancements in cancer management. Despite comprising only 2.5 % of cancers in women, ovarian cancer ranks as the fifth leading cause of cancer-related deaths among women, with patients frequently receiving late diagnoses. Chemotherapy, a primary treatment, frequently causes chemotherapy-induced peripheral neuropathy (CIPN), affecting over 60 % of patients and leading to severe sensory, motor, and autonomic nerve impairments. This often necessitates dosage reduction or discontinuation of treatment, thereby increasing

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… For example, she experiences difficulty with tasks such as buttoning and zipping her clothing, tying her shoes, and holding eating utensils. …

Decoding Cancer Risk: Understanding Gene-Environment Interactions in Cancer Development.

While lifestyle choices or behavioral patterns remain the most significant factors influencing cancer risk, environmental exposure to certain chemicals, both manufactured and natural, may also contribute to an individual's likelihood of developing cancer. This interplay of factors, coupled with an aging demographic and shifting lifestyle patterns, has led to an increasing prevalence of cancer in recent years. This study examines the environmental and behavioral factors that contribute to anomalies in the immune system and increase the risk of developing cancer. Significant environmental and oc