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Intention to use contraceptives and its correlates among reproductive age women in selected high fertility sub-saharan Africa countries: a multilevel mixed effects analysis.

BACKGROUND: Intention to use contraceptive methods has an overriding importance to better visualize the women's future needs and more likely … ception was 59.20%, 53.30%, 42.32%, 37.88%, 37.63%, 35.25%, 31.32%, 20.64%, 20.30% in Burkina Faso, Burundi, Niger, Mali, DR. Congo, Nigeria, Angola, Gambia, and Chad respectively. Age; 15-24 (AOR = 3.72, 95% CI, 3.58, 3.86) and 25 - 24 years (AOR = 2.81, 95% CI, 2.74, 2.89), education of women; primary (AOR = 1.16, 95% CI, 1.13, 1.20), and secondary (AOR …

Suggested Improvements to the Current East African Community Medicines Regulatory Harmonization Joint Review Process and a Proposed New Review Model for this Initiative.

BACKGROUND: In 2012, the East African Community Medicines Regulatory Harmonization (EAC-MRH) initiative was established to improve access to safe, effective, and high-quality medical products to patients in the East African region. The East African Community (EAC) Partner States, the Republic of Burundi, Democratic Republic of Congo, Republic of Rwanda, United Republic of Tanzania, Republic of Kenya, Republic of South Sudan, and the Republic of Uganda, have a population of 290 million inhabitants. The timely access to medical products for this population was to be achieved through harmonisatio…

Spatiotemporal patterns of Rift Valley fever virus in Africa: a retrospective genomic epidemiology and phylodynamic modelling study.

BACKGROUND: Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen causing outbreaks in humans and ruminants across Africa and … e human and livestock isolates comprised large (n=56), medium (n=53), and small (n=45) collected in Burundi (2018), Kenya (2007, 2018, 2019, 2021, and 2022), and Rwanda (2018 and 2022). Our dataset revealed that RVFV exhibited low overall genetic diversity. Lineage C, however, showed evidence of active evolution, with substitution rates ranging from 3·58 …

Targeted FMD Vaccines for Eastern Africa: The AgResults Foot and Mouth Disease Vaccine Challenge Project.

As one of the most infectious livestock diseases in the world, foot and mouth disease (FMD) presents a constant global threat to animal trad … ed to meet the needs of Eastern Africa (EA). The Project targets the following Pool Four countries: Burundi, Ethiopia, Kenya, Rwanda, Tanzania and Uganda. The Project is being run in two phases: a development phase, which will encourage the production of regionally relevant vaccines, and a cost-share phase, designed to help to reduce the price of these va …

Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.

BackgroundMultiple myeloma (MM) is a growing global public health challenge. Known epidemiological data suggest that MM accounts for approximately 10% of all hematologic malignancies and remains the second most common hematologic cancer worldwide. This study utilized data from the 2021 Global Burden of Diseases (GBD) study to evaluate the prevalence, incidence, mortality, disability-adjusted life years (DALYs), and attributable risk factors of MM from 1990 to 2021, and to project future trends for the next 15 years.MethodsGBD 2021 data were analyzed to assess MM's global burden using four key

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… The largest decreases in ASIR were observed in Burundi, Northern Mariana Islands and Tajikistan ( Supplementary Table S5 ). … In contrast, the Northern Mariana Islands [1.45 (95%CI −1.69 to −1.21)], Singapore [−1.44 (95%CI −1.55 to −1.33)], and Burundi [−1.2 (95%CI −1.4 to −1.01)] had the largest decrease in MM AMSR from 1990 to 2021 ( Supplementary Table S5 ). …

Effective cataract surgical coverage in adults aged 50 years and older: empirical estimates from population-based surveys in 68 countries and modelled estimates for 2000-30.

BACKGROUND: Cataract is the leading cause of blindness worldwide despite treatment being very cost-effective. To stimulate efforts to addres … mates of eCSC6/18. Country estimates for eCSC6/18 from surveys ranged from 2·1% (95% CI 0·9-3·4) in Burundi (2024) to 77·7% (72·9-82·5) in Qatar (2023). Globally, we predicted eCSC6/18 of 48·2% (39·7-57·2) in 2025, increasing by 8·4 percentage points (8·1-8·6) between 2020 and 2030 (from 43·9% [36·6-51·2] to 52·3% [41·4-62·7]). Uncorrected refractive erro …

A global, regional, and national survey on burden and Quality of Care Index (QCI) of hematologic malignancies; global burden of disease systematic analysis 1990-2017.

BackgroundHematologic malignancies (HMs) are a heterogeneous group of cancers that comprise diverse subgroups of neoplasms. So far, despite the major epidemiologic concerns about the quality of care, limited data are available for patients with HMs. Thus, we created a novel measure-Quality of Care Index (QCI)-to appraise the quality of care in different populations.MethodsThe Global Burden of Disease data from 1990 to 2017 applied in our study. We performed a principal component analysis on several secondary indices from the major primary indices, including incidence, prevalence, mortality, ye

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… In 2017, QCI spanned from as high as 99.8 in Australia, Iceland, and Finland, to values as low as 9.6 in Eritrea, 9.8 in Somalia, and 10.2 in Burundi. … Countries located in this region including Eritrea, Somalia, Burundi, and Central African Republic had the lowest QCI score in our analysis. …

The outside medical evacuation for cancer from Madagascar.

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… In the Muteganya et al. study in Burundi from 1986 to 1993, radiotherapy-being unavailable-was the only reason for requesting outside MEDEVAC for cervical cancer patients who needed it [ 9 ]. …

Demographic, epidemiological, and health transitions: are they relevant to population health patterns in Africa?

BackgroundStudies of trends in population changes and epidemiological profiles in the developing world have overwhelmingly relied upon the concepts of demographic, epidemiological, and health transitions, even though their usefulness in describing and understanding population and health trends in developing countries has been repeatedly called into question. The issue is particularly relevant for the study of population health patterns in Africa and sub-Saharan Africa, as the history and experience there differs substantially from that of Western Europe and North America, for which these conce

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… Sub-Saharan Africa | 39.6; 47.4 | 13.0; 27.7 | 19.7; 28.9 | 5.4; 6.8 | 1980 | 36.23 | 52.94 | 0.32 | 0.15 Africa | 36.7; 48.1 | 11.8; 26.8 | 21.3; 28.8 | 4.9; 6.7 | 1975 | 37.38 | 55.55 | 0.36 | 0.15 Eastern Africa | 39.4; 49.3 | 11.1; 27.0 | 22.3; 30.3 | 5.4; 7.1 | 1980 | 37.03 | 55.85 | 0.30 | 0.27 Burundi …

Donor Evaluation for Hematopoietic Stem and Progenitor Cell Collection

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… Kosrae, Federated States of Micronesia Marshall Islands New Caledonia Palau Papua New Guinea Samoa Solomon Islands Tonga Asia Bangladesh Burma (Myanmar) Cambodia India Indonesia Laos Malaysia Maldives Pakistan Philippines Singapore Thailand Timor-Leste (East Timor) Vietnam Angola Benin Burkina-Faso Burundi … Kosrae, Federated States of Micronesia Marshall Islands New Caledonia Palau Papua New Guinea Samoa Solomon Islands Tonga Asia Bangladesh Burma (Myanmar) Cambodia India Indonesia Laos Malaysia Maldives Pakistan Philippines Singapore Thailand Timor-Leste (East Timor) Vietnam | Angola Benin Burkina-Faso Burundi …

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leadi … s countries, with less than 20% of additional years spent in poor health in Bosnia and Herzegovina, Burundi, and Slovakia, whereas in Bahrain all the extra years were spent in poor health. In 2017, the highest estimate of HALE at birth was in Singapore for both females (75·8 years [72·4-78·7]) and males (72·6 years [69·8-75·0]) and the lowest estimates we …

Fortification of rice with vitamins and minerals for addressing micronutrient malnutrition.

BACKGROUND: Rice fortification with vitamins and minerals has the potential to increase the nutrition in rice-consuming countries where micr … nducted in India, three in Thailand, two in the Philippines, two in Brazil, one each in Bangladesh, Burundi, Cambodia, Indonesia, Mexico and the USA. Two studies involved non-pregnant, non-lactating women and 10 involved pre-school or school-age children. All 17 studies reported fortification with iron. Of these, six studies fortified rice with iron only; …

Mapping Cancer in Africa: A Comprehensive and Comparable Characterization of 34 Cancer Types Using Estimates From GLOBOCAN 2020.

ObjectiveCancer incidence and mortality rates in Africa are increasing, yet their geographic distribution and determinants are incompletely characterized. The present study aims to establish the spatial epidemiology of cancer burden in Africa and delineate the association between cancer burden and the country-level socioeconomic status. The study also examines the forecasts of the cancer burden for 2040 and evaluates infrastructure availability across all African countries.MethodsThe estimates of age, sex, and country-specific incidence and mortality of 34 neoplasms in 54 African countries, we

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… Angola | 20,327 [18,854–21,915] | 130.6 | 86.5 | 12,599 [11,627–13,652] | 0.62 Benin | 6,747 [5,981–7,610] | 95.8 | 69.3 | 4,662 [4,065–5,347] | 0.69 Botswana | 2,010 [1,874–2,156] | 109.5 | 63.4 | 1,112 [1,036–1,193] | 0.55 Burkina Faso | 12,045 [10,722–13,531] | 112 | 84.4 | 8,695 [7,649–9,884] | 0.72 Burundi …

Глобальное, региональное и национальное бремя множественной миеломы, 1990 в адрес 2021 и прогнозы 2035:: анализ исследования глобального бремени болезней; 2021.

Предыстория и объективная мультипликативная миелома (ММ) является вторым по распространенности гематологической злокачественности. Цель этого исследования состояла в том, чтобы оценить глобальное бремя множественной миеломы по всему миру. 204 странами и территориями 1990 в адрес 2021Данные для этого исследования были получены из Глобального центра по проблемам заболеваемости (ГБЗ) 2021 набор данных, содержащий всеобъемлющую информацию о глобальном и региональном бремени 369 - болезни, травмы и 88 факторов риска в различных областях 204 странами и территориями 1990 в адрес 2021. Мы проанализиро

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… In contrast, the most pronounced downward trends were observed in Northern Mariana Islands (EAPC, −1.35 per 100,000 persons; 95% UI: −1.61 to −1.08), Republic of Burundi (EAPC, −1.19 per 100,000 persons; 95% UI: −1.40 to −0.98), and Republic of Tajikistan (EAPC, −0.66 per 100,000 persons; 95% UI: −0.93 …

A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors.

Observational and ecological studies are generally used to determine the presence of effect of cancer risk-modifying factors. Researchers generally agree that environmental factors such as smoking, alcohol consumption, poor diet, lack of physical activity, and low serum 25-hdyroxyvitamin D levels are important cancer risk factors. This ecological study used age-adjusted incidence rates for 21 cancers for 157 countries (87 with high-quality data) in 2008 with respect to dietary supply and other factors, including per capita gross domestic product, life expectancy, lung cancer incidence rate (an

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… The other 70 countries: Algeria, Angola, Bangladesh, Benin, Bolivia, Botswana, Burkina Faso, Burundi, Cambodia, Cameroon, Cape Verde, Central African Republic, Chad, Chile, China, Comoros, Djibouti, Ethiopia, French Polynesia, Gabon, Gambia, Ghana, Guadeloupe, Guinea, Guinea-Bissau, Honduras, India, …

Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with e

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate how disease burden changes with development. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 20

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… Other regions where observed all-ages DALY rates fell below expected levels, included western Europe (eg, Portugal, Spain, France, Italy, and Sweden); western sub-Saharan Africa (eg, Burkina Faso, Niger, and Senegal); eastern sub-Saharan Africa (eg, Burundi and Ethiopia); north Africa and the Middle …

50th ESCP Symposium on Clinical Pharmacy, Polypharmacy and ageing - highly individualized, interprofessional, person-centered care : 19–21 October 2022, Prague, Czech Republic

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Abstracts cont.

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Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

BACKGROUND: Timely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 provides cause-specific mortality estimates measured in counts, rates, and years of life lost (YLLs). GBD 2023 aimed to enhance our understanding of the relationship between age and cause of death by quantifying the probability of dying before age 70 years (70q0) and the mean age at death by cause and sex. This study enables comparis