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Entomological baseline data collection and power analyses in preparation of a mosquito swarm-killing intervention in south-western Burkina Faso.

BACKGROUND: Insecticides are currently the main tools used to reduce the transmission of malaria; therefore, the development of resistance to insecticides in malaria vectors is of major concern for malaria control. The resistance level to pyrethroids is particularly high in the Western region of Burkina Faso and may affect the efficacy of insecticidal bed nets and indoor residual spraying. Adult mosquito swarming and other nocturnal behaviours exhibit spatial and temporal patterns that suggest potential vulnerability to targeted space spraying with effective insecticides. Indeed, targeted spac

New Mosquitocide Derived From Volcanic Rock.

Malaria, dengue, yellow fever, and the Zika and West Nile Viruses are major vector-borne diseases of humans transmitted by mosquitoes. According to the World Health Organization, over 80% of the world's population is at risk of contacting these diseases. Insecticides are critical for mosquito control and disease prevention, and insect insecticide resistance is on the increase; new alternatives with potentially different modes of action from current chemistry are needed. During laboratory screening of industrial minerals for insecticide activity against Anopheles gambiae (Giles) (Diptera: Culic…

Practical management plan for invasive mosquito species in Europe: I. Asian tiger mosquito (Aedes albopictus).

Aedes albopictus, also known as the "Asian Tiger Mosquito", is an invasive mosquito species to Europe causing high concern in public health due to its severe nuisance and its vectorial capacity for pathogens such as dengue, chikungunya, yellow fever and Zika. Consequently, the responsible authorities implement management activities to reduce its population density, possibly to below noxious and epidemiological thresholds. In urban areas, these aims are difficult to achieve because of the species' ability to develop in a wide range of artificial breeding sites, mainly private properties. This d

Characterization of Tolypocladium cylindrosporum (Hypocreales, Ophiocordycipitaceae) isolates from Brazil and their efficacy against Aedes aegypti (Diptera, Culicidae).

AIMS: To survey and to characterize entomopathogenic fungi as natural enemies of mosquitoes in Central Brazil. METHODS AND RESULTS: Tolypocladium cylindrosporum (Hypocreales, Ophiocordycipitaceae) was isolated for the first time in South America by using Aedes aegypti (Diptera, Culicidae) as sentinel larvae in a stagnant mosquito breeding site in a secondary tropical forest. Two isolates were morphologically and molecularly identified, and their activity tested against A. aegypti eggs, larvae and adults. CONCLUSIONS: Findings emphasize the importance of T. cylindrosporum as a natural fungal

Наша гонка за будущее.

Потребность в борьбе с комарами документально зафиксирована в книгах истории с комментариями о скоплениях комаров, смерти от таинственных высоких температур и желтой лихорадки, малярии и денге. Бумага отслеживает появление в Соединенных Штатах противомоскитных средств до настоящего времени с целью заглянуть в будущее. Обсуждаются нормативные положения и их влияние на методы борьбы с комарами. В нем упоминается о просвещении и подготовке персонала. Мнение автора о роли АМСА в будущем в борьбе с комарами и проведении исследований является авторитетным и лидерским.

Совпадение в аннотации оригинала
The need for mosquito control is documented from history books with comments about hoards of mosquitoes, deaths from mysterious high fevers, and yellow fever, malaria and dengue. The paper traces the birth of mosquito control in the United States to the present time with a look into the future. Regulations are discussed and their effect on mosquito control m…

Maximizing the Potential of Attractive Targeted Sugar Baits (ATSBs) for Integrated Vector Management.

Due to the limitations of the human therapeutics and vaccines available to treat and prevent mosquito-borne diseases, the primary strategy for disease mitigation is through vector control. However, the current tools and approaches used for mosquito control have proven insufficient to prevent malaria and arboviral infections, such as dengue, Zika, and lymphatic filariasis, and hence, these diseases remain a global public health threat. The proven ability of mosquito vectors to adapt to various control strategies through insecticide resistance, invasive potential, and behavioral changes from ind…

Efficacy of ivermectin for malaria vector control: a systematic review and meta-analysis of randomized clinical trials.

BACKGROUND: Despite global malaria control efforts, malaria continues to cause approximately 241-249 million cases and over 600,000 deaths annually. Ivermectin, a broad-spectrum antiparasitic drug with endectocidal activity against mosquitoes feeding on treated hosts, has been proposed as a potential malaria vector-control intervention. OBJECTIVE: To systematically evaluate the effectiveness of ivermectin in reducing malaria transmission outcomes in adult populations, including malaria incidence, prevalence, mosquito mortality, and safety outcomes. METHODS: Following PRISMA 2020 guidelines,

New solutions against the dengue global threat: opportunities for Wolbachia interventions.

Reliance on traditional vector control methods, such as insecticides and "clean up" source reduction efforts for reducing mosquito breeding sites, has proven increasingly ineffective and costly in the battle against dengue. The Wolbachia-based mosquito replacement strategy, which replaces wild mosquitoes with mosquitoes trans-infected with Wolbachia bacteria, preventing up to 77% dengue transmission, represents an advancement in prevention. Integrating this approach into current routine dengue control efforts could reduce dengue incidence. However, challenges such as implementation costs, the

The urgent need for more research on Wolbachia-based mosquito interventions in public health.

The release of Wolbachia pipientis-infected Aedes aegypti mosquitoes has emerged as a novel strategy to reduce the transmission of arboviruses such as dengue, chikungunya, and Zika. Wolbachia-based approaches to dengue control include population replacement, which reduces vector competence by establishing Wolbachia in wild populations of Aedes aegypti, and population suppression, which lowers mosquito densities through cytoplasmic incompatibility. Field trials of the population replacement strategy, based on wMel Wolbachia-infected mosquitoes, have shown variable success and concerns persist a

Improving Wolbachia-based control programs in urban settings: Insights from spatial modeling.

Mosquito-borne diseases such as dengue remain major global public health challenges, especially in areas facing rapid climate change. Conventional mosquito control often proves ineffective or unsustainable, highlighting the need for innovative approaches. One promising strategy is releasing Aedes aegypti mosquitoes infected with Wolbachia, a bacterium that reduces mosquito-borne virus transmission. However, spatial heterogeneity across release areas complicates large-scale Wolbachia deployment, particularly in complex urban landscapes. High spatial variation and limited access to certain regio…

A taste of a toxin paradise: Xenorhabdus and Photorhabdus bacterial secondary metabolites against Aedes aegypti larvae and eggs.

Aedes-transmitted arboviral infections such as Dengue, Yellow Fever, Zika and Chikungunya are increasing public health problems. Xenorhabdus and Photorhabdus bacteria are promising sources of effective compounds with important biological activities. This study investigated the effects of cell-free supernatants of X. szentirmaii, X. cabanillasii and P. kayaii against Ae. aegypti eggs and larvae and identified the bioactive larvicidal compound in X. szentirmaii using The EasyPACId method. Among the three tested bacterial species, X. cabanillasii exhibited the highest (96%) egg hatching inhibitio

Boosting the efficacy of fungal biocontrol: miRNA339-5p-mediated mosquito immunity regulation.

BACKGROUND: Aedes mosquitoes are vectors for numerous viral diseases, including dengue, zika, chikungunya, and yellow fever. Therefore, unde … 5p through advanced genetic engineering techniques to bolster the efficacy of existing fungal-based mosquito control strategies, providing a promising approach in the fight against mosquito-borne diseases. © 2024 Society of Chemical Industry.

Residual Efficacy of Insecticides Sprayed on Different Types of Surfaces Against Leishmaniasis and Filariasis Vectors in Egypt.

Determination of the residual activity of insecticides is an essential component in the selection of an appropriate insecticide for indoor residual spraying operations. This report presents the results of a laboratory study to evaluate the residual bio-efficacy of four insecticides sprayed on the most common house-wall surfaces that occur in Egypt (wood, mud, and cement) against Phlebotomus papatasi (Scopoli, 1786) (Diptera: Psychodidae) and Culex pipiens Linnaeus, 1758 (Diptera: Culicidae). In total, 28,050 P. papatasi females and 31,275 Cx. pipiens females were subjected to the WHO cone bioa

Tracking the Asian tiger mosquito (Aedes albopictus) in Austria: benefits of combining expert-based monitoring with citizen science data.

BACKGROUND: The Asian tiger mosquito (Aedes albopictus) is an invasive species and a competent vector of numerous pathogens. Its establishment in Austria represents a growing public health concern, underscoring the need for effective surveillance strategies. In Austria, two complementary monitoring systems are implemented, an expert-based ovitrap monitoring programme and a citizen science-based monitoring approach. This study investigates whether combining structured expert monitoring with citizen science reporting provides measurable benefits and identifies which advantages are most relevant.

A Multiagency Approach to Reducing West Nile Virus Risk in Richmond County, Georgia, in 2015.

The Richmond County Mosquito Control program's mission statement is to incorporate strategies of integrated mosquito control management that are effective, practical, and environmentally safe and protect the health of Richmond County residents, as well as promote public education, in order to prevent large mosquito populations and the diseases that they transmit. To this end, the program coordinates efforts with other county agencies in order to provide better service. This is a small program with limited resources, so in an effort to provide better integrated mosquito management, the mosquito…

Field implementation of the sterile insect technique against Aedes aegypti in Recife, Brazil: operational challenges and impact of release frequency on vector dynamics.

BACKGROUND: The sterile insect technique (SIT) is an environmentally friendly tool for suppressing Aedes aegypti populations. While promising in controlled settings, its application in large urban environments presents logistical and biological challenges. This trial focused on releasing sterile males, sent from a long-distance production facility to suppress the local mosquito population. METHODS: Sterile males of Ae. aegypti were mass-reared, irradiated, and transported 712.2 km from a central facility to Recife, Brazil. Releases were performed once (SIT 1 ×) or twice per week (SIT 2 ×). En

Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico.

Mosquito-transmitted viruses such as dengue are a global and growing public health challenge. Without widely available vaccines, mosquito control is the primary tool for fighting the spread of these viruses. New mosquito control technologies are needed to complement existing methods, given current challenges with scalability, acceptability, and effectiveness. A field trial was conducted in collaboration with the Communities Organized to Prevent Arboviruses project in Ponce, Puerto Rico, to measure entomological and epidemiological effects of reducing Aedes aegypti populations using Wolbachia i…

Transmission of transgenic mosquito-killing fungi during copulation.

Entomopathogenic fungi engineered to express insect-specific neurotoxins have demonstrated potential as microbial control agents against malaria mosquitoes. Currently, the primary application method is via direct contact of spores with indoor resting mosquitoes. However, many malaria-transmitting mosquitoes feed and rest outdoors. To target these, we have developed an alternative application method that exploits the lethality of transgenic fungi as a sexually transmitted mosquito disease. This approach has both a wider interdisciplinary significance and important implications for preventing mo

Effectiveness of the sterile insect technique in controlling Aedes albopictus as part of an integrated control measure: evidence from a first small-scale field trial in Switzerland.

BACKGROUND: The invasive Asian tiger mosquito (Aedes albopictus) poses growing health risks across Europe. In Switzerland, a preliminary field trial was conducted to assess the feasibility of integrating the sterile insect technique (SIT) into existing integrated vector management (IVM), which includes breeding site removal and application of biological larvicides. SIT involves repeated releases of irradiated sterile males, which mate with wild females, producing non-viable eggs and leading to population decline. METHODS: Following a preliminary release test in 2022, a small-scale SIT trial t

Larvicidal potential of Pseudomonas mosselii isolated from Aedes (Diptera: Culicidae) egg surfaces against dengue vector mosquitoes and its impact on non-target organisms.

The critical impact of mosquito-borne diseases on public health, along with the failure of current control strategies, highlights the need for novel mosquito control approaches mainly in tropical countries. This study explored the larvicidal properties of bacterial isolates from the egg surfaces of Aedes aegypti L. and Aedes albopictus Skuse (Diptera: Culicidae), the primary and secondary dengue vector mosquitoes in Sri Lanka. Among 30 bacterial isolates, a local strain of Pseudomonas mosselii Quesnel isolated from the egg surfaces of the dengue vectors demonstrated strong larvicidal activity …