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Performance validity test failure rates among neuropsychological outpatients clinically referred for persistent Long COVID cognitive symptoms following mild SARS-CoV-2 disease severity.

OBJECTIVE: Persisting cognitive symptoms following SARS-CoV-2 infection (Long COVID) has become an increasingly common referral for neuropsy … anding (Test of Memory Malingering-Trial 1) and four embedded PVTs (Reliable Digit Span; California Verbal Learning Test-Brief Form Forced Choice; Brief Visuospatial Memory Test-Revised Recognition Discriminability; Stroop Color and Word Test-Word Reading T-Score), as well as a 11 neuropsychological test scores assessing the major domains of cognition, which were …

Pre-stroke physical activity and Val66Met (rs6265) genotype of BDNF gene correlate with the post-stroke cognitive outcome: a prospective cohort study.

Pre-stroke physical activity may protect against post-stroke cognitive impairment (PSCI) via neuroplastic mechanisms including BDNF signalli … igher pre-stroke METs correlated with superior baseline performance across global cognition (MoCA), verbal learning/recall (CVLT indices), attention and executive measures. After adjustment, CVLT long-delay free recall (LDFR) and TMTA remained significant (β for CVLT LDFR = 0.000087; β for TMTA = - 0.000336 per MET-min/week, p < 0.05). At 6 months several correla …

EEG stabilization and cognitive gains after pulse steroid therapy in developmental and/or epileptic encephalopathy with spike-wave activation in sleep: A prospective cohort study.

BACKGROUND: Developmental and/or epileptic encephalopathy with spike-wave activation in sleep (D/EE-SWAS) is a rare paediatric epileptic enc … quency at 24 months. Neuropsychological outcomes revealed significant improvements in attention and verbal learning overall, with meaningful domain-specific cognitive recovery predominantly confined to the idiopathic group. CONCLUSION: A structured six-month pulse IVMP regimen was associated with early spike suppression and delayed network stabilisation. Etiolog …

Central Nervous System T-cell immune architecture, and not HIV burden, tracks with cognition under long-term viral suppression.

Despite effective antiretroviral therapy, HIV persists in the central nervous system (CNS) and may contribute to neuroinflammation and cognitive impairment. How viral persistence, immune responses, and regional CNS T-cell architecture relate to cognitive functioning remains unclear. We performed a cross-sectional, multi-compartmental immune-genomic study in 12 people with HIV on long-term viral suppression enrolled in the Last Gift rapid autopsy program. Quantitative HIV reservoir measures (total-episomal DNA, unspliced-multiply spliced RNA) and paired αβ T-cell receptor repertoire (TCRR) sequ

Effects of Baduanjin on cognitive performance and upper limb function in patients receiving chemotherapy after breast cancer surgery: A randomized controlled trial.

BACKGROUND: Post-operative breast cancer patients undergoing chemotherapy frequently experience concurrent upper limb dysfunction and chemot … er Therapy-Cognitive Function (FACT-Cog). The neuropsychological test battery included the Auditory Verbal Learning Test (AVLT), the Trail Making Test (TMT), and the Digit Symbol Substitution Test (DSST). Upper limb function was assessed using the Constant-Murley Score (CMS). All assessments were performed at baseline (T0), Week 4 (T1), Week 8 (T2), and Week 12 ( …

Cerebellar gray matter atrophy and altered structural covariance networks are associated with cognitive impairment in type 2 diabetes mellitus.

BACKGROUND: The prevalence of type 2 diabetes mellitus (T2DM) is steadily increasing, with central nervous system complications commonly man … th Clock Drawing Test scores, while GMV of the right crus I was positively correlated with Auditory Verbal Learning Test (AVLT) scores. In addition, GMV of the right lobule VIIb was positively associated with both AVLT and Grooved Pegboard Test (GPT) scores, and GMV of the left lobule IX was positively correlated with GPT scores. With respect to network integrity …

Sex-specific brain morphological and network differences in patients showing Parkinson's disease with and without possible rapid eye movement sleep behavior disorder.

BACKGROUND: Sex is a crucial determinant in the clinical manifestations of diseases. However, previous studies have not clarified whether al … elation between morphological network metrics and cognitive performance, as measured by the Hopkins Verbal Learning Test-Revised (HVLT-R) memory scores. CONCLUSION: The presence of more significant sex-related differences in brain morphological changes in the PD-pRBD group in comparison with the PDnon-pRBD group highlights the importance of considering sex-relat …

Neurocognitive trajectories in long COVID: Evidence from longitudinal analyses.

BACKGROUND: Patients frequently report symptoms of cognitive impairment or "brain fog" after acute COVID-19 infection, but the trajectory of … es from cognitive measures of attention, working memory, processing speed, executive functions, and verbal learning and memory improved progressively through 42 months post-COVID. However, despite the improvements, on average, measures of processing speed and executive functioning remained ≥1 standard deviation below the normative mean. Having a body mass index o …

High‑Resolution T2 MRI Volumetry of Medial Temporal Lobe Subregions Predicts Cognitive Decline Across the Alzheimer's Disease Continuum.

Atrophy of medial temporal lobe (MTL) subregions is an early biomarker of Alzheimer's disease (AD). This study aimed to examine the relation … ate memory recall in AD was associated with atrophy in CA, DG, while in early stages of MCI, poorer verbal learning scores correlated with atrophy in the CA, DG, BA35, SUB, and CS regions. Moreover, diminished Logical Memory Delayed Recall was associated with atrophy in the CA, BA35, and PHC subfields among AD subjects. These findings support the value of atrophy …

Enhanced machine learning predictive modeling for delirium in elderly ICU patients with COPD and respiratory failure: A retrospective study based on MIMIC-IV.

BACKGROUND AND OBJECTIVE: Elderly patients with Chronic obstructive pulmonary disease (COPD) and respiratory failure admitted to the intensive care unit (ICU) have a poor prognosis, and the occurrence of delirium further worsens outcomes and increases hospitalization costs. This study aimed to develop a predictive model for delirium in this patient population and identify associated risk factors. METHODS: Data for the machine learning model were obtained from the MIMIC-IV database. Feature variable screening was conducted using Lasso regression and the best subset method. Four models-K-neares

Delayed primacy recall in AVLT is associated with medial temporal tau PET burden in cognitively unimpaired adults.

BACKGROUND: Alzheimer's disease (AD) can be diagnosed by in vivo abnormalities of amyloid-β plaques (A) and tau accumulation (T) biomarkers. … l cortex (PHC) and hippocampus (H) as outcomes, cross-sectional memory scores from the Rey Auditory Verbal Learning Test as predictors (total and delayed recall, along with serial position scores) and control variables, in separate analyses for each outcome and predictor. The sample was then stratified by biomarker profile and ANCOVAs were conducted with the stro …

Neurocognitive Functions Among Patients Dependent on Natural Opium: A Comparative Cross-Sectional Study.

INTRODUCTION: Opioid use has been associated with neurocognitive impairments. These deficiencies play a key role in perpetuating addictive b … ord Test (SCWT), F-A-S Test, Digit Span Test (DST), Trail Making Test (TMT) A & B, and Rey Auditory Verbal Learning Test (RAVLT), was used for assessment. Urinary opioid levels were measured in the patients. Partial correlation was employed to investigate the association of cognitive functions with the level of exposure to natural opium. RESULTS: The demographic …

Осуществимость и предварительные последствия вмешательства группы по танцованию на базе балета в случае повторного многоразового склероза: экспериментальное исследование.

Справочная информация: Групповые танцевальные мероприятия (ГБДИ) стали многообещающим подходом к реабилитации от неврологических расстройств. В рамках этого экспериментального исследования была проведена оценка осуществимости и предварительных последствий ГБДИ для моторной функции, когнитивирования, усталости и качества жизни лиц с множественным склерозом (RRMS). Методы: В ходе выступления в течение 10 недель в течение недели проводились два балета продолжительностью 60 мин., которые были организованы в форме 10 минут разогрева, 40 мин балетных упражнений и 10 минут растягивания. Оценки провод

Совпадение в аннотации оригинала
Background: Group-based dance interventions (GBDIs) have emerged as a promising approach to rehabilitation for neurological disorders. This … ox and block test (BBT) and 9-hole peg test (9HPT). Regarding cognitive functions, the Rey auditory verbal learning test (RAVLT), symbol digit modalities test (SDMT), and trail making test A and B (TMT-A/B) were administered, while fatigue and quality of life were assessed using the modified fatigue impact scale (MFIS) and the Short Form survey-36 (SF-36), respec …

Oxygen supplementation and cognitive function in long-COVID.

BACKGROUND: Patients can experience persistent cognitive complaints and deficits in long-COVID. Inflammation and capillary damage may contribute to symptoms by interfering with tissue oxygenation. METHODS: This was an exploratory pilot crossover study designed to describe the effects of supplemental oxygen (portable oxygen concentrator, POC) on cognitive performance and peripheral and cerebral oxygen saturation at rest and exercise. Participants with long-COVID (n = 21) were randomized 1:1 to: 1) POC (3h/day) for 2 weeks followed by standard of care (Control) for 2 weeks or 2) Control for 2 w

Effects of Tai Chi combined with tDCS on cognitive function in patients with MCI: a randomized controlled trial.

BACKGROUND: Mild cognitive impairment (MCI) is a critical stage of dementia. Previous reviews have suggested that physical exercise combined … st color reaction time compared to the WAS and WAT groups (P < 0.05), a higher increase in Auditory Verbal Learning Test-immediate recall than the TCS and WAT groups (P < 0.05), a shorter visual reaction time than the TCS group (P < 0.05), and a shorter sustained attention time compared to the WAT group (P < 0.05). CONCLUSION: Tai Chi combined with tDCS effectiv …

Serum glial cell line-derived neurotrophic factor (GDNF) a potential biomarker of executive function in Parkinson's disease.

OBJECTIVE: Evidence shows that the impairment of executive function (EF) is mainly attributed to the degeneration of frontal-striatal dopami … 0.01; r HVA = -0.323, P < 0.01) scores. Serum GDNF levels were positively correlated with auditory verbal learning test (AVLT-H) (r = 0.252, P < 0.05) and SFT (r = 0.275, P < 0.05) scores. Serum HVA levels showed a positively correlation with digit span test (DST) (r = 0.277, P < 0.01) scores. Stepwise linear regression analysis suggested that serum GDNF and HVA …

Speech rehabilitation in children with cochlear implants using a multisensory (French Cued Speech) or a hearing-focused (Auditory Verbal Therapy) approach.

INTRODUCTION: Early exposure to a rich linguistic environment is essential as soon as the diagnosis of deafness is made. Cochlear implantation (CI) allows children to have access to speech perception in their early years. However, it provides only partial acoustic information, which can lead to difficulties in perceiving some phonetic contrasts. This study investigates the contribution of two spoken speech and language rehabilitation approaches to speech perception in children with CI using a lexicality judgment task from the EULALIES battery. Auditory Verbal Therapy (AVT) is an early interven

Determining the neurocognitive profile of children with tuberous sclerosis complex within the Western Cape region of South Africa.

BACKGROUND: Tuberous sclerosis complex (TSC) is a multisystem genetic disorder associated with a wide spectrum of cognitive impairments that can often result in impaired academic, social and adaptive functioning. However, studies investigating TSC have found it difficult to determine whether TSC is associated with a distinct cognitive phenotype and more specifically which aspects of functioning are impaired. Furthermore, children with TSC living in low-income and middle-income countries, like South Africa, experience additional burdens due to low socio-economic status, high mortality rates and

Vascular Cognitive Impairment and cognitive decline; a longitudinal study comparing different types of vascular brain injury - The TRACE-VCI study.

BACKGROUND: Little is known about the trajectories of cognitive decline in relation to different types of vascular brain injury in patients … nts (43%)). We assessed cognitive functioning at baseline and follow-up, including the Rey Auditory Verbal Learning Test (RAVLT), Trail Making Test (TMT) A and B, category naming task and MMSE. The association of different types of vascular brain injury with cognitive decline was evaluated with linear mixed models, including one type of vascular brain injury (dic …

Altered dynamic brain activity and its association with memory decline after night shift-related sleep deprivation in nurses.

AIMS AND OBJECTIVES: To investigate, for the first time, aberrant time-varying local brain activity in nurses following night shift-related … c resonance imaging and memory function assessment (by Complex Figure Test (CFT) and the California Verbal Learning Test, Second Edition (CVLT-II)) twice, once in a rested wakefulness (RW) state and another after SD. By combining the sliding-window approach and amplitude of low-frequency fluctuation (ALFF) analysis, the dynamic ALFF (dALFF) variability was calcul …