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Viral etiology of severe lower respiratory tract infections in SARS-CoV-2 negative hospitalized patients during the COVID-19 pandemic in Kuwait.

BACKGROUND: The prevalence of respiratory infections is largely underexplored in Kuwait. The aim of our study is to determine the etiology o … ovirus (HRV) (32.7 %), respiratory syncytial virus (RSV) (20.9 %), metapneumovirus (HMPV) (14.1 %), bocavirus (13.2 %), and influenza A (12.7 %). The proportion of pathogens detected was highest in the under-5 age group, while HKU1 (44.4 %) predominated in the elderly (>50 years). CONCLUSION: Our study reveals a high prevalence of respiratory viruses in se …

Molecular and Epidemiologic Analysis of Diarrheal Pathogens in Children With Acute Gastroenteritis in Bangladesh During 2014-2019.

BACKGROUND: Diarrheal disease is one of the leading causes of childhood morbidity and mortality in the 21st century in developing countries. … Rotavirus was the most prevalent (26.3%), followed by adenovirus (5.7%), norovirus (5.4%) and human bocavirus (4.9%). Dual infection between rotavirus and E. coli accounted for the largest portion of coinfection (48%). Diarrhea (77%) and abdominal pain (65%) were most common followed by vomiting (63%), fever (43%) and dehydration (39%). E. coli and V. chole …

Survey of Respiratory Virus in Patients Hospitalised for Acute Exacerbations of Heart Failure - A Prospective Observational Study.

INTRODUCTION: Respiratory virus (RV) infections have been implicated in acute exacerbation cardiopulmunary conditions. This study aimed to d … nfluenza virus, rhinovirus, parainfluenza virus (HPIV), human coronavirus (HcoV), adenoviurs, human bocavirus (HboV), human metapneumovirus (hMPV), and respiratory syncytial virus (RSV). RESULTS: Twenty-five (13%) had RVs detected by RV multiplex PCR. There comprised 9 rhinoviruses (36%), 4 influenza A viruses (16%), 3 HPIV (12%), 3 HCoV (12%), 2 adenoviru …

Two novel dromedary camel bocaparvoviruses from dromedaries in the Middle East with unique genomic features.

The recent emergence of Middle East respiratory syndrome (MERS) coronavirus and its discovery from dromedary camels has boosted interest in the search for novel viruses in dromedaries. While bocaparvoviruses are known to infect various animals, it was not known that they exist in dromedaries. In this study, we describe the discovery of two novel dromedary camel bocaparvoviruses (DBoVs), DBoV1 and DBoV2, from dromedary faecal samples in Dubai. Among 667 adult dromedaries and 72 dromedary calves, 13.9 % of adult dromedaries and 33.3 % of dromedary calves were positive for DBoV1, while 7.0 % of a

Detection of 12 respiratory viruses by duplex real time PCR assays in respiratory samples.

Different viruses can be responsible for similar clinical manifestations of respiratory infections. Thus, the etiological diagnosis of respi … ding CoV OC43 and CoV HKU1), parainfluenza viruses type 1, 2, 3 and 4, human adenoviruses and human bocaviruses. The 2 target viruses of each duplex reaction were distinguishable by the melting temperatures of their amplicons. The 6 duplex real time PCR assays were applied for diagnostic purpose on 202 respiratory samples from 157 patients. One hundred fift …

Epidemiology and lagged climatic drivers of pediatric viral lower respiratory tract infections in Tianjin, China (2023-2025).

BACKGROUND: Following the lifting of pandemic-era restrictions, China experienced a sharp resurgence in pediatric respiratory infections; ho … n sequencing for human rhinovirus (HRV), adenovirus (ADV), respiratory syncytial virus (RSV), human bocavirus (HBoV), influenza virus (IFV), and human metapneumovirus (HMPV). Pathogen-climate associations were estimated using a quasi-Poisson model that adjusted for seasonality, secular trend, and lagged meteorological exposures. RESULTS: Among 2,597 virus- …

Korea 2024-2025 Influenza and Respiratory Virus Laboratory Surveillance Report.

OBJECTIVES: This study characterizes the detection patterns of respiratory viruses and the virological characteristics of influenza viruses … man metapneumovirus (4.8%), human coronavirus (4.7%), respiratory syncytial virus (3.6%), and human bocavirus (3.2%). The influenza virus subtypes included A(H1N1)pdm09 (39.6%), influenza B virus (36.8%), and A(H3N2) (23.6%). Circulating influenza viruses were genetically and antigenically similar to the 2024-2025 seasonal vaccine strains, and no antiviral- …

Long-Term Dynamics of Pediatric Respiratory Pathogens Before, During, and After the COVID-19 Pandemic: Evidence From Nine Years of Surveillance in the Netherlands (2015-2023).

Respiratory tract infections (RTIs) are common in children and are caused by viral and bacterial pathogens. However, seasonal variability an … st often. Pathogen co-detections occurred in 20.8% of all positive samples, with the combination RV-bocavirus (3.6%) being the most common. In < 12-month-olds, the need for hospitalization was associated with RV (84%), RSV (84%), or influenza (80%). After adjusting for covariates, the need for respiratory support was associated with infections caused by hum …

Respiratory virus detections in children presenting to an Australian paediatric referral hospital pre-COVID-19 pandemic, January 2014 to December 2019.

Acute respiratory infections cause significant paediatric morbidity, but for pathogens other than influenza, respiratory syncytial virus (RS … and enterovirus were detected year-round and low seasonal strength was observed for adenovirus and bocavirus. Biennial seasonal patterns were observed for influenza B and parainfluenza virus 2. Co-detections occurred in 5,428 samples, predominantly with two (4284, 79.0%) or three viruses (904, 16.7%). The most common co-detections were rhinovirus-adenoviru …

A new epidemic wave of Bordetella pertussis in paediatric population: impact and role of co-infections in pertussis disease.

BACKGROUND: In recent months, Bordetella pertussis has reappeared after maintaining a low rate for many years. Although pertussis is usually … and Parainfluenza-virus were the most prevalent in our pediatric population. Co-infections of human bocavirus with B.pertussis were observed exclusively in patients with respiratory failure. CONCLUSIONS: Our results highlighted an increase in B.pertussis cases from January to May 2024, reaching a peak of cases in the month of May. This study shows a high r …

[The Republic of Korea 2023-2024 Influenza and Respiratory Viruses Laboratory Surveillance Report].

OBJECTIVES: The study aim was to examine the detection patterns of respiratory virus circulation in the Republic of Korea from week 36 of 20 … %), respiratory syncytial virus (5.0%), human metapneumovirus (4.2%), human coronavirus (3.8%), and bocavirus (3.2%). CONCLUSIONS: The continuous surveillance of influenza and respiratory virus trends is essential to inform vaccine strain selection and enhance public health response strategies. Our division will conduct continuous surveillance of the epide …

Targeted Enrichment Sequencing Utilizing a Respiratory Pathogen Panel for Genomic Wastewater-Based Viral Epidemiology in Uruguay.

Human respiratory and enteric viruses are responsible for substantial morbidity and mortality worldwide. Wastewater-based epidemiology utili … h sequences of SARS-CoV-2. Additionally, several other viral pathogens were detected, such as human Bocavirus, human Parechovirus, Enterovirus A71, and Enterovirus D68; however, for these viruses further analysis was limited due to the small genomic regions or low-read coverage obtained. While the RPIP panel necessitates substantial sequencing depth and may …

Positive and negative viral associations in patients with acute respiratory tract infections in primary care: the ECOVIR study.

INTRODUCTION: Acute respiratory infections (ARIs) are the most common viral infections encountered in primary care settings. The identificat … 43, Influenza virus (H1 and H3 subtypes), Influenza virus B, Para-Influenza viruses (PIVs) 1-4, and Bocavirus (BoV)]. RESULTS: Among the 668 analyzed samples, 66% were positive for at least one virus, of which 7.9% were viral codetections. The viral detection was negatively associated with the age of patients. BoV, ADV, and HRV occurred more significantly …

Changing epidemiology of influenza and other respiratory viruses in the first year of COVID-19 pandemic.

INTRODUCTION: We aimed to determine the epidemiological change in influenza and other respiratory tract viruses isolated from patients with … za (PIV) 1,2,3,4, coronaviruses (CoVs) NL 63, 229E, OC43 and HKU1, human metapneumovirus (MPV) A/B, bocavirus, respiratory syncytial virus (RSV) A/B and adenovirus. RESULTS: We retrospectively analyzed the results of 319 nasopharyngeal swab samples. The average age of 199 (62.4%) male and 120 (37.6%) female patients between the ages of 0-92 was 16 years. W …

More than just a common cold: Endemic coronaviruses OC43, HKU1, NL63, and 229E associated with severe acute respiratory infection and fatality cases among healthy adults.

Respiratory viral infection can cause severe disease and hospitalization, especially among children, the elderly, and patients with comorbid … using official protocols. This cross-sectional study analyzed the presence of coronaviruses (HCoV), bocavirus (HBoV), metapneumovirus (hMPV), and rhinovirus in patients who died of SARI despite not having comorbidities, and that were negative for IAV, IBV, RSV, HAdV, and hPIV. Nasopharyngeal aspirates/swabs from patients were used for nucleic acid extractio …

ВИДОЛИЧЕСКАЯ ЭТИОЛОГИЯ И РЕЗУЛЬТАТЫ НИЖНЕЙ РЕАГИРУЮЩЕЙСЯ ПРОФЕССИОНАЛЬНОЙ ИНВЕСТИЦИИ, СООТВЕТСТВУЮЩЕЙ ХАРАКТЕРИСТИКЕ ДЕТЕЙ, ПРИНАДЛЕЖАЩИХ В ПИКЮ.

ЦЕЛЬ: Определение вирусной этиологии острых инфекций нижних дыхательных путей (LRTIs), их клинической значимости и прогнозирования среди детей, страдающих серьезными заболеваниями. DESIGN: Было проведено перспективное описательное исследование. СИТТИНГ: Отделение интенсивной педиатрической помощи (PICU) Стамбульского медицинского университета, Учебный и научно-исследовательский госпиталь Гозтепе, Стамбул, Турция. ПАТИЕНТЫ: В общей сложности 115 пациентов, госпитализированных в ПИКУ, были оценены на предмет включения в исследование. Исключаются дети с координированными свойствами и дети, не нуж

Совпадение в аннотации оригинала
OBJECTIVE: To determine the viral etiology of severe lower respiratory tract infections (LRTIs), their clinical significance and prognosis a … entified in 20.6% of the patients, the most common in this subgroup being rhinovirus. Patients with bocavirus infection had a higher likelihood of needing invasive mechanical ventilation (IMV) at presentation. Children who died were likely to be < 12 months old, have ARDS, hepatitis, pneumomediastinum, multiple viral infection, and required IMV support with …

Comprehensive Detection of Respiratory Bacterial and Viral Pathogens in the Middle Ear Fluid and Nasopharynx of Pediatric Patients With Acute Otitis Media.

BACKGROUND: Acute otitis media (AOM) is a common ear infection caused by respiratory viruses and bacteria of the nasopharynx. The present study aimed to detect various respiratory viruses and bacteria in middle ear fluid (MEF) and nasopharyngeal aspirates (NPA) using polymerase chain reaction (PCR). METHODS: We collected MEF and NPA samples from 122 pediatric patients with AOM. Real-time PCR detected 11 types of respiratory viruses (respiratory syncytial virus A/B, parainfluenza virus 1/2/3, human metapneumovirus, influenza virus A/B, adenovirus, human bocavirus and rhino virus) and 7 types o…

Risk factors for bronchiolitis severity: A retrospective review of patients admitted to the university hospital from central region of Slovenia.

AIM: Study's objective was to identify risk factors associated with bronchiolitis severity. METHODS: A retrospective chart review of all ch … requently detected viruses were respiratory syncytial virus (RSV), human rhinovirus (hRV) and human bocavirus (hBoV) (57.5%, 272/473; 25.6%, 121/473; 18.4%, 87/473). Patient groups differed in Wang Respiratory Score for the severity of bronchiolitis (P < 0.001). No differences regarding the causative viruses were found. There was a lower proportion of child …

Viral etiologies and epidemiology of patients with acute respiratory infections based on sentinel hospitals in Gansu Province, Northwest China, 2011-2015.

Understanding etiological role and epidemiological profile is needed to improve clinical management and prevention of acute respiratory infe … an parainfluenza (PIV, 4.0%), adenovirus (ADV, 2.1%), human metapneumovirus (hMPV, 1.6%), and human bocavirus (hBoV, 0.7%). Compared with URTI, RSV was more likely identified in pneumonia (χ2  = 12.720, P < 0.001) and hCoV was more commonly associated with bronchitis than pneumonia (χ2  = 15.019, P < 0.001). In patients aged less than 5 years, RSV showed th …

Does atopy affect the course of viral pneumonia?

BACKGROUND: The presence of atopy is considered as a risk factor for severe respiratory symptoms in children. The objective of this study wa … (18.9%), adenovirus (10%), human metapneumovirus (8%), parainfluenza (5.2%), coronavirus (6%), and bocavirus (1.6%) were isolated from respiratory samples. Eighty-five (30.4%) children had severe pneumonia. Atopic sensitisation was found in 21.4% of the patients. Ever wheezing (RR: 1.6, 95% CI: 1.1-2.4), parental asthma (RR: 1.5, 95% CI: 1.1-2.2), other al …