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Molecular Characterization of Cefoxitin-Resistant Coagulase-Negative Staphylococci From Frequently Touched Surfaces of Hospital and Urban-Built Environments of Central India.

Coagulase-negative staphylococci (CoNS) are the major pathogen (hospital as well as environmental) and their emerging multidrug-resistant (M … biotics and three marker gene characteristics, namely, ß-lactamase, cefoxitin screen, and inducible clindamycin resistance via the VITEK 2 system. These strains were 100% resistant to benzylpenicillin and oxacillin, and approximately 50% were resistant to vancomycin. Amplified mecA gene fragments were sequenced, and SNP analysis was performed alongside a stan …

Environmental Footprint of Antibiotics: A Multi-Source Investigation of Wastewater Systems in UAE.

Background/Objectives: Antibiotic resistance is a growing global health threat, requiring comprehensive investigations into the occurrence, … p to 247.9 ng/mL, while cefuroxime and vancomycin ranged between 0.2 and 10.9 ng/mL across samples. Clindamycin was notably prevalent in wastewater treatment plant samples (up to 10.9 ng/mL), whereas vancomycin and cefuroxime were dominant in residential community samples, reflecting diverse antibiotic usage patterns and persistence in treatment systems. Conc …

Exploring the prevalence and antibiotic resistance of Listeria monocytogenes in diverse food commodities across Sikkim, India.

Listeria monocytogenes is a foodborne pathogen of significant public health concern, especially due to its ability to survive in a wide rang … r of positive samples. AST revealed notable resistance to penicillin, ampicillin, erythromycin, and clindamycin, with high susceptibility to tetracycline and trimethoprim-sulfamethoxazole. The MAR index values ranged from 0 to 0.81 with 41 isolates showing higher values above 0.2. Our findings highlight the need for improved hygiene practices, regular surveil …

Rising trend of Enterococcus species as pathogen, and its antimicrobial susceptibility pattern in western Gujarat.

INTRODUCTION: Infections by enterococci pose a unique challenge as their ability to grow in extreme environments and intrinsic resistance to cephalosporin, clindamycin, and multidrug resistance. Enterococcus faecalis and Enterococcus faecium cause infections ranging from urinary tract infections (UTI) to bacteremia. METHODOLOGY: A retrospective study on urine and blood specimens was conducted over 11 months (February-December 2024) to assess the prevalence, age-gender distribution, species isolation, and vancomycin resistant enterococci (VRE) profile to aid treatment. A total of 4,549 urine a…

Mycoplasma hominis Intracranial Abscess Diagnosed by Characteristic Colonies Obtained Through Extended Culture: Case Report and Literature Review.

Mycoplasma hominis (M. hominis) causes genitourinary infections and pregnancy-related complications. Reports of intracranial abscesses due t … onies revealed the presence of M. hominis. On day 27, the treatment was changed to levofloxacin and clindamycin for treatment of the intracranial abscesses caused by M. hominis. Antibiotic therapy was continued for an additional 52 days until the abscesses disappeared. No recurrences were observed. When bacteria are suspected to be the cause of an intracrania …

Brevibacterium Species Infections in Humans-A Narrative Review.

Brevibacterium species are Gram-positive, non-sporulating, coryneform, aerobic rods that are catalase positive and exhibit a distinctive tra … Brevibacterium spp. was highly resistant to the combination of trimethoprim with sulfamethoxazole, clindamycin, and common beta-lactams. The most commonly used antimicrobials were vancomycin and aminoglycosides. The mortality was about 10%. Clinicians and laboratory personnel should consider this pathogen in the differential diagnosis in patients with malign …

Optimization of Anthralin Microemulgel Targeted Delivery for Psoriasis and Acne.

Background: Anthralin is known for its efficacy in treating psoriasis and acne, possessing poor solubility. Addressing these limitations, th … growth proving that formulation has anti-psoriatic activity. Conclusions: Combination therapy with Clindamycin might improve efficacy while reducing antibiotic resistance risks.

Pyomyositis in Children: A 15-year Retrospective Study From a Tertiary Care Pediatric Hospital in Portugal.

BACKGROUND: Pyomyositis is a primary infection of the skeletal muscle, commonly occurring in tropical countries in children. Treatment is st … t common isolated organism (36.0%). Most patients were treated with intravenous flucloxacillin plus clindamycin (55.2%) for a median of 14 days (7;30) and a median total duration of 29 days (14;72). Drainage was only performed in 20.7% of patients, of which 6/15 were in the suppurative phase. All patients improved without functional impairment at 6-month foll …

Analysis of standard aerobic bacterial culture and sensitivity results from three laboratories for canine pyoderma.

OBJECTIVES: The aim of this study was to evaluate the reported bacteria and antibiotic sensitivities of aerobic bacterial cultures taken fro … e more likely to have disagreement: gentamicin (40%), doxycycline (26.6%), enrofloxacin (26.6%) and clindamycin (13%). CLINICAL SIGNIFICANCE: Staphylococcus species and their sensitivities were reliable and reproducible, which agree with recent studies; however, the additional bacteria reported varied considerably, which may lead to the choice of a broader s …

Vaginitis: Diagnosis and Treatment.

Vaginitis is a general term for inflammation of the vagina with symptoms such as vulvovaginal itching, burning, irritation, dyspareunia, odo … probe test. Bacterial vaginosis is treated with oral or intravaginal metronidazole or intravaginal clindamycin. Vulvovaginal candidiasis is managed with topical or oral antifungals. Trichomoniasis is treated with oral metronidazole or tinidazole. When treating trichomoniasis, testing for reinfection, as well as other sexually transmitted infections, is recom …

Nasal Septal Abscess Causing Near-Fatal Toxic Shock Syndrome With Multiorgan Dysfunction: A Case Report.

Nasal septal abscess (NSA) is a rare collection of pus between the nasal septum and the surrounding lining tissues. We report a case of meth … ined, and blood and pus cultures grew MRSA. Antibiotics were adjusted to meropenem, vancomycin, and clindamycin. On day 4, the patient developed severe acute respiratory distress syndrome, requiring prone positioning. After receiving a course of IVIG, his condition began to improve. His ventilation/perfusion (P/F) ratio improved, urine output normalized, and …

Листерия моноцитогены и ауреат ауреуса Staphylococus у пациента с множественной миеломой: отчет по делу.

ВВЕДЕНИЕ: Listeria monocitogenes представляет собой грозный патоген, который представляет собой значительную угрозу для иммунокомпромизации и может вызвать редкие нетипичные формы заболевания, особенно осложненные при кондиционировании Staphylococcus aureus. КАСЕ: Мы представляем случай пациента с моноцитогенесом менингоэнцефалитом, эндокардитом, сепсисом и С. ауреусом остеомиелитом, высветив сложность лечения распространяемой полимикробной инфекции. A 64-year-old Женщина с множественной миеломой лечится химиотерапией с температурой, изменившимся психическим состоянием, тошнотой и диареей в от

Совпадение в аннотации оригинала
INTRODUCTION: Listeria monocytogenes is a formidable pathogen that poses a significant threat to immunocompromised and might cause rare atyp … the aortic valve. The patient was initially treated with ceftriaxone, ampicillin, gentamicin, with clindamycin and ciprofloxacin for osteomyelitis and later with ampicillin/sulbactam and ciprofloxacin to cover both pathogens and pathologies. Due to an allergic reaction to ampicillin, treatment was changed to vancomycin. After 4 weeks of antibiotic therapy pa …

Epstein-Barr Virus (EBV) Masquerading as Exudative Tonsillitis and Rash in a Transgender Adolescent.

A 19-year-old transgender adolescent on hormonal therapy with a history of recent hospitalization for exudative tonsillitis presented with w … , hemophagocytic lymphohistiocytosis (HLH) was considered but not confirmed. Management included IV clindamycin for tonsillitis, corticosteroids for airway inflammation, and doxycycline for atypical pneumonia. Over the 10-day hospitalization, the patient showed gradual improvement, with resolution of the rash and all other symptoms. The rash was ultimately di …

Changes in the epidemiology and antimicrobial resistance patterns of Streptococcus pneumoniae from pediatric community acquired pneumonia patients attended in a Chinese hospital during the COVID-19 pandemic.

PURPOSE: The COVID-19 pandemic has altered the infection dynamics of numerous pathogens. This study aimed to elucidate its impact on Strepto … nd the resistance rates to certain antibiotics during the COVID-19 pandemic. The resistance rate to clindamycin and quinupristin-dalfopristin increased, whereas the resistance rate to tetracycline, trimethoprim-sulfamethoxazole, telithromycin, and proportion of multi-drug resistant isolates decreased. The number of S. pneumoniae strains and resistant isolates …

Staphylococcus spp. as part of the microbiota and as opportunistic pathogen in free-ranging black-tuffed marmosets (Callithrix penicillata) from urban areas: Epidemiology, antimicrobial resistance, and pathology.

BACKGROUND: Marmosets (Callithrix sp.), including black-tuffed marmosets (C. penicillata), are neotropical primates that can be highly adapt … e of S. epidermidis was resistant to multiple antimicrobials (penicillin, cefoxitin, ciprofloxacin, clindamycin, and erythromycin). We considered S. aureus as the main staphylococci to colonize black-tuffed marmosets. CONCLUSIONS: Black-tuffed marmosets can be colonized by several Staphylococcus species, most frequently by S. aureus, and the majority of isol …

Triple Therapy IDP-126 Gel for Acne Treatment: A Systematic Review and Meta-Analysis.

Acne vulgaris (AV) is a common dermatological condition that ranges from mild comedones to severe inflammatory nodules and scarring. Effective management is essential for improving patients' quality of life. The recent FDA approval of IDP-126 (Cabtreo™), a novel triple-combination gel, meets these needs by combining clindamycin phosphate, benzoyl peroxide, and adapalene into a single formulation. This systematic review and meta-analysis aimed to assess the efficacy, safety, and impact of IDP-126 on quality of life in managing AV. The study's goal was to provide clinicians with the necessary in…

Antimicrobial Resistance Trends in Hidradenitis Suppurativa Lesions.

Background/Objectives: Antibiotic (AB) therapy is the first step in managing hidradenitis suppurativa (HS). Knowledge of the local patterns … n were observed for Gram-negative isolates. Resistances of 62.5%, 61.5%, and 53.8% to erythromycin, clindamycin, and penicillin, respectively, were observed in the anaerobes. Conclusions: Patients with HS displayed considerable resistance to bacterial proliferation. The revised therapeutic guidelines for HS should incorporate the latest insights into bacteria …

Assessing the potential for improved predictive capacity of antimicrobial resistance in outpatient Staphylococcus aureus isolates using seasonal and spatial antibiograms.

BACKGROUND: While the use of cumulative susceptibility reports, antibiograms, is recommended for improved empiric therapy and antibiotic ste … al and spatial antibiograms were created for five commonly used antibiotic classes: cephalosporins, clindamycin, macrolides, tetracycline, trimethoprim/sulfamethoxazole. RESULTS: A total of 338,681 S. aureus isolates obtained in VHA outpatient settings from 2010 to 2019 and 6,817 isolates obtained in UIHC outpatient settings from 2014 to 2019 were used to ge …

Fatal Case of Pneumocystis Jirovecii Pneumonia (PJP) During Treatment for Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome.

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is an acute, rare and potentially fatal drug reaction. To date, limit … Pneumocystis jirovecii. Despite targeted therapy with trimethoprim/sulfamethoxazole, primaquine and clindamycin successively, no remission was observed. Chest CT scans exhibited multiple exudations in both lungs, indicative of interstitial pneumonia. Unfortunately, the patient's oxygenation progressively declined, leading to his untimely demise. This rare cas …

Robinsoniella peoriensis Infections in Humans-A Narrative Review.

Robinsoniella peoriensis is a Gram-positive, strictly anaerobic, spore-forming, rod-shaped bacterium belonging to the phylum Firmicutes and … itis, and peritonitis. The only isolated species was R. peoriensis, and antimicrobial resistance to clindamycin was 50%, but was 0% to the combination of piperacillin with tazobactam, aminopenicillin with a beta-lactamase inhibitor, and metronidazole which were the most commonly used antimicrobials for the treatment of these infections. The overall mortality …