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The effect of age on the tolerability of intraperitoneal chemotherapy, complication rate, and survival in patients with ovarian cancer.

OBJECTIVE: We sought to determine if patient age influenced chemotherapy completion rate, complication rate, or progression free survival (PFS) among patients who received intraperitoneal (IP) chemotherapy for epithelial ovarian, fallopian tube, or primary peritoneal cancers. METHODS: Charts for patients receiving IP chemotherapy between January 2006 and September 2009 were reviewed at three institutions. Primary outcomes included completion rate of planned IP chemotherapy, complication rate, and PFS. Completion rates were categorized as 0-49%, 50-99%, or 100% of planned treatments were deliv

Inhaled nitric oxide increases survival rates in newborn rats with congenital diaphragmatic hernia.

The high mortality of newborn infants with congenital diaphragmatic hernia (CDH) can be partly attributed to pulmonary hypertension causing extrapulmonary right-to-left shunting with subsequent severe hypoxemia. Inhaled nitric oxide (NO) may reduce elevated pulmonary artery pressure and has been successfully improve arterial oxygenation in some newborns with CDH. However, it is not clear whether inhaled NO will actually improve survival of newborns with CDH. We therefore investigated the effect of inhaled NO on the survival rate of newborn rats with CDH following intrauterine exposure to nitro…

[Thromboxane A2 and granulocyte elastase after severe trauma--relationship to complications and survival rates].

Of 64 polytraumatized patients with a mean injury severity score of 33.1, 42 showed marked systemic release of thromboxane B2 and granulocyte elastase during the initial 18 hours after trauma, reaching peak arterial levels of greater than 1,000 pg/ml and ng/ml, respectively. If those patients ("responders": plasma TXB2 greater than 250 pg/ml) were compared with the remaining 22 ("non-responders": TXB2 less than 250 pg/ml) the following became obvious: "Late" mortality (greater than 3 d) was 31% in responders, which is significantly higher than in non-responders (9%). No correlation was observe

[The atrial pacemaker as therapy in sinus node disease: retrospective analysis of complications and rate of survival].

The implantation of an atrial pacing device represents an established mode of therapy for bradycardia in sinus node dysfunction. However, co … s. 82 +/- 6% of patients survived the first 5 years, 52 +/- 14% survived for 10 years. The 5 years' survival rate was not different from that of the normal population. From this we conclude that atrial pacing can be safely done with an AAI system as long as there are no signs of an AV-block. Atrial fibrillation develops less often on AAI pacing than on VVI paci …

Sex and Health Disparities Impacts on Survival Rates for Patients With Major Salivary Gland Tumors.

OBJECTIVE: To evaluate demographic and clinical factors influencing survival in patients with major salivary gland tumors (MSGTs) using the surveillance, epidemiology, and end results (SEER) database. STUDY DESIGN: A retrospective cohort study using SEER data from 2000 to 2021. SETTING: Data were collected from the SEER registry, a comprehensive database capturing cancer statistics across the United States. METHODS: Patients diagnosed with major salivary gland malignancies were analyzed for demographic factors, including age, sex, race, marital status, and income, as well as clinical variab

Impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study.

BACKGROUND: Combination therapy with a beta-lactam and an aminoglycoside is currently recommended for the empirical treatment of urosepsis. Nephrotoxicity is the most common adverse effect of aminoglycosides and acute kidney injury (AKI) has a significant prognostic impact in septic shock. This study aimed to evaluate the impact of empirical antibiotic therapy with or without an aminoglycoside on survival and renal outcomes in patients admitted to the intensive care unit (ICU) with urosepsis. METHODS: This multicenter, retrospective, comparative study included all adults admitted to the ICU f

Renal Function and its Time-Sensitive Influence on Survival Rates of Acute Myocardial Infarction.

BACKGROUND: Primary percutaneous coronary intervention is the preferred treatment for acute myocardial infarction. However, in patients with chronic kidney disease (CKD), the use of contrast media can exacerbate renal dysfunction, often necessitating alternative strategies. The impact of CKD on acute myocardial infarction prognosis, particularly in the context of percutaneous coronary intervention, is not fully understood. METHODS AND RESULTS: This study utilized real-world registry data from the OACIS (Osaka Acute Coronary Insufficiency Study) to evaluate prognosis across different CKD grade

Criteria and prognostic factors for survival and success rates for autotransplantation in the area of first and second molars.

Autotransplantation of immature third molars is an effective treatment option, offering high success rates, minimal complications, and notab … ines. Nine studies met the inclusion criteria for qualitative and quantitative analysis. The pooled survival rate was consistently high across studies, estimated at 91.867% (95% CI: 85.058% to 96.741%), while the success rate, though slightly lower, remained substantial at 90.162% (95% CI: 79.813% to 97.067%). Key prognostic factors identified include the devel …

Total femoral replacement for oncologic indications: Functional outcomes, complications, and implant survival rates.

OBJECTIVE: Total femoral replacements for oncological indications are a rare indication, and there is limited data on functional outcomes, complications, and implant survival rates. The purpose of this study was to investigate functional outcomes, the rate and nature of com plications associated with this technique, and the survival rates of the implant used. METHODS: This is a retrospective case series from a single subspeciality orthopedic oncology unit in an urban referral center that evalu ated patients treated between January 2000 and May 2023. A total of 27 patients were included in the…

HLA Compatibility and Graft Survival Rates Among Related and Unrelated Donors in Renal Transplantation.

Human leukocyte antigen (HLA) compatibility between donors and recipients plays a critical role in graft survival in renal transplantation. This study evaluates the impact of HLA mismatching on graft survival and rejection among renal transplant recipients with related and unrelated donors, considering factors such as age, sex, ABO blood type, and anti-HLA antibodies. We investigated the graft survival rates between related and unrelated donors in a prospective cohort study conducted from 2018 to 2020 at Cho Ray Hospital and People's Hospital 115 in Vietnam, involving 126 related and 82 unrela…

Incidence and survival rates of primary uterine carcinosarcoma in Korea: a National Cancer Registry study.

OBJECTIVE: To investigate the incidence and survival rates of primary uterine carcinosarcoma (UCS) in Korea. METHODS: From the Korea Central Cancer Registry, we identified patients diagnosed with primary UCS between 1999 and 2018 and collected their information, including age at diagnosis, Surveillance, Epidemiology, and End Results (SEER) summary stage, and treatment. Age-standardized incidence rates (ASRs) and annual percent changes (APCs) were calculated. Baseline characteristics and overall survival (OS) were compared by study periods, ages, and stages at initial diagnosis. RESULTS: Over…

Establishment of a Reproducible Ischemic Stroke Model in Nestin-GFP Mice with High Survival Rates.

An accumulation of evidence shows that endogenous neural stem/progenitor cells (NSPCs) are activated following brain injury such as that suf … ) but highly reproducible in Nestin-GFP mice (CB-17 background). In a further investigation of mice survival rates up to 28 days after MCA occlusion, all Nestin-GFP mice (CB-17 background) survived the period, whereas Nestin-GFP mice (C57BL/6 background) frequently died within 1 week and exhibited a higher mortality rate. Immunohistochemistry analysis of Nestin …

Disparities in the Diagnosis, Treatment, and Survival Rate of Cervical Cancer among Women with and without Disabilities.

IntroductionNot much is known regarding the disparities in cancer care between women with and without disabilities.ObjectivesThe aim of this study was to investigate the potential disparities in the diagnosis, treatment, and survival of women with cervical cancer with and without disabilities.MethodsWe performed a retrospective cohort study and linked the National Disability Database, Korean Central Cancer Registry, and Korean National Health Insurance claims database. Charlson comorbidity index was used for adjusting the comorbidity. The study population comprised 3 185 women with disabilitie

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… Chemo-radiotherapy is the primary treatment for larger, localized, or advanced cervical cancers, with no significant differences in survival. 5 Surgery and concurrent chemo-radiotherapy for early-stage cervical cancers (stages I–II) have 5-year survival rates of 80–90%. 6 , 7 The 5-year survival rate … rates. 24 Shin et al. 25 reported that disabled lung cancer patients underwent fewer staging work-ups and treatments; they also had lower survival rates. …

Higher incidence of retinopathy of prematurity in extremely preterm infants associated with improved survival rates.

AIM: This study assessed possible reasons for the increasing incidence of retinopathy of prematurity (ROP) since mid-2015 at our institution … as the only significant risk factor the for severest ROP stage (P = .0045). CONCLUSION: Increased survival rate of extremely preterm infants was associated with an increased incidence of ROP at our institution. Despite the increase, the incidence is still very low compared with other countries. No other additive factors were identified.

De Novo and Nevus-Associated Melanomas: Different Histopathologic Characteristics but Similar Survival Rates.

The clinical significances of de novo and nevus-associated melanomas are controversial. In this study, we investigated the correlations of t … th aggressive histopathologic variables, such as tumor depth, ulceration and high mitotic rate, the survival rates of de novo and nevus-associated melanomas are similar.

Influence of exposing dental implants into the sinus cavity on survival and complications rate: a systematic review.

BACKGROUND: After tooth loss, the posterior maxilla is usually characterized by limited bone height secondary to pneumatization of the maxil … up were included in the qualitative assessment. RESULTS: Eight studies provided information on the survival rate, with a global sample of 493 implants, being the weighted mean survival rate 95.6% (IC 95%), after 52.7 months of follow-up. The level of implant penetration (≤ 4 mm or > 4 mm) did not report statistically significant differences in survival rate (p …

Multifactorial Analysis of Prognostic Factors and Survival Rates Among 706 Mucosal Melanoma Patients.

BACKGROUND: The hypothesis that mucosal melanomas from different anatomic sites would have different prognostic features and survival outcome was tested in a multifactorial analysis. METHODS: Complete clinical and pathological information from 706 mucosal melanoma patients from different anatomical sites was compared for overall survival (OS) and prognostic factors. RESULTS: Mucosal melanomas arising from different anatomical sites did not have any significant differences in OS in a multivariate analysis (p = 0.721). Among all 706 stage I-IV mucosal melanoma patients, depth of tumor invasion