Результаты поиска

Cardiac Amyloidosis in Older Adults With a Focus on Frailty: JACC: Advances Expert Consensus.

Amyloidosis, which is caused by misfolded proteins that form amyloid fibrils, is predominantly diagnosed in older adults. Although previously considered a rare disease, increased awareness and noninvasive diagnostic methods have resulted in a rise in diagnoses. As a multisystem disease that affects multiple organ systems (cardiac, gastrointestinal, renal, and neurological), there is significant overlap with both geriatric conditions and common conditions in heart failure. Frailty is recognized as a distinct biological syndrome of declines across multiple physiological systems, which prevents m

Symptom experiences and self-management strategies of patients with haematological malignancy undergoing chemotherapy: A qualitative study.

ObjectiveTo explore symptom experiences and self-management strategies from the haematological malignancy patient's perspective.MethodsA qualitative descriptive approach was used to provide a direct and comprehensive understanding of the symptoms experienced and self-management strategies during treatment among patients with haematological malignancy. Fourteen patients with haematologic malignancies who received chemotherapy at a Chinese tertiary hospital were selected using purposeful sampling. Data were collected via semi-structured interviews and one-on-one patient sessions. The collected d

Oncology Nursing During a Pandemic: Critical Reflections in the Context of COVID-19.

ObjectivesTo provide a critical reflection of COVID-19 in the context of oncology nursing and provide recommendations for caring for people affected by cancer during this pandemic.Data sourcesElectronic databases, including CINAHL, MEDLINE, PsychINFO, Scopus, professional web sites, and grey literature were searched using Google Scholar.ConclusionNurses are key stakeholders in developing and implementing policies regarding standards of care during the COVID-19 pandemic. This pandemic poses several challenges for oncology services. Oncology nurses are providing a pivotal role in the care and ma

Patient-Centered Insights on Treatment Decision Making and Living with Acute Myeloid Leukemia and Other Hematologic Cancers.

Expectations relating to treatment and survival, and factors influencing treatment decisions are not well understood in adult patients with acute myeloid leukemia. This study analyzed combined findings from a targeted literature review with patient-reported information shared on YouTube to further understand patient perspectives in hematologic cancers and, in particular, acute myeloid leukemia. The targeted literature review included articles concerning patient (aged ≥ 18 years) experiences or perspectives in acute myeloid leukemia or other hematologic cancers. YouTube video selection criteria

Perspectives of patients, partners, primary and hospital-based health care professionals on living with advanced cancer and systemic treatment.

PurposeAn emerging group of patients lives longer with advanced cancer while receiving systemic treatment. This study aimed to investigate psychosocial aspects of living longer with advanced cancer, and experiences with psychosocial care, from the perspectives of patients, partners, and health care professionals (HCPs).MethodsFrom May to December 2020, participants were purposively selected. In-depth, semi-structured interviews were conducted by video or phone call, containing open questions regarding psychosocial aspects and psychosocial care in oncology. The data was analysed following thema

Миксобактериальная реакция на воздействие метильясмоната свидетельствует о вкладе в набор микропрепараторов на заводы.

Химические обмены между растениями и микробами в пределах ризобиомы имеют решающее значение для развития общинной структуры. Такие летучие корневые экюды, как фитохормоновый метилжасмонат (MeJA), способствуют принятию различных мер реагирования в связи со стрессом на растения, и они были причастны к тому, чтобы играть определенную роль в поддержании микробных сообществ. Миксобактерия является компетентным хищником растительных патогенов и, как правило, считается полезной для ризобиомов. Хотя было предложено использовать миксобактерию растений для защиты от патогенов, не известно о каких-либо с

Racial and ethnic variations in caregiving-related physical, emotional, and financial strain during COVID-19 among those caring for adult cancer patients.

PurposeCancer caregiving is shown to be a burdensome experience in typical times. The purpose of this study was to describe cancer caregivers' emotional, physical, and financial strain during the COVID-19 pandemic and compared to preCOVID-19, and explore racial and ethnic variations in caregiver strain.MethodsWe conducted a cross-sectional online survey using Lucid, LLC, incorporating quotas for race, ethnicity, gender and age. Caregivers had to be adults living in the USA and currently providing unpaid care to an adult cancer patient (i.e., during COVID-19) and prior to the pandemic. We asses

Development of Psychosocial Distress in Cancer Survivors and Its Potential Prognostic Impact on Survival: A Scoping Review.

BackgroundWhile single-point assessments of psychosocial distress have been associated with survival outcomes, investigations examining longitudinal changes in psychosocial distress and survival outcomes remain limited.AimsThis scoping review evaluates existing literature on longitudinal distress patterns and their association with survival outcomes.MethodsA comprehensive search was performed in PubMed, Web of Science, and PsycInfo databases up to January 2025. Studies were eligible if they included adult cancer survivors, measured psychological distress using validated instruments at minimum

An Observational Study of the First 100 Patients Undergoing Nocturnal Every-Other-Day Online Hemodiafiltration: Clinical Outcomes and Patient and Technique Survival.

Background: High-volume online hemodiafiltration (OL-HDF) has proven to be the most efficient dialysis modality and to offer better clinical outcomes in patients on hemodialysis. Longer and more frequent dialysis sessions have demonstrated clinical and survival benefits. Methods: A single-center observational study of the first one hundred patients on nocturnal every-other-day OL-HDF was conducted with the aim of reporting the experience with this treatment schedule and evaluating analytical and clinical outcomes as well as the patient and technique survival. Results: Nocturnal OL-HDF on alter

The organization, weaknesses, and challenges of the control of thalidomide in Brazil: A review.

The drug thalidomide has resurged in the world market under restrictive conditions for marketing and use. In Brazil, there are still cases of pregnant women using thalidomide even after the implementation of laws that regulate the control of use (Law No. 10.651/2003 and Collegiate Board Resolution No. 11/2011). The objective of this study was to discuss the control of thalidomide use in Brazil, based on a scoping review of the scientific literature, documents, and data from the Ministry of Health. A total of 51 studies and documents related to the following subthemes were selected: (1) organiz

Hope and Acceptance at the End of Life: Impact of Spirituality on Patients in Palliative Care.

IntroductionPalliative care aims to improve the quality of life of patients with serious illnesses. In this type of care, spirituality is placed alongside other dimensions: physical, psychological, and social. The end of life brings confrontation with dilemmas such as "none of this makes sense" or "was it worth it?" The acceptance or rejection of the journey presents spirituality as a dimension that accompanies the person in their existence. Interventions that allow for a review of life help facilitate reflection on regrets, unresolved issues, and an understanding of the legacy that generates

Потенциал транскраниального прямого течения (tDCS) в повышении качества жизни пациентов с множественным склерозом: обзор и обсуждение механизмов действий.

Фон/цели: Множественный склероз (MS) является наиболее распространенным неизлечимым нетравматическим расстройством у молодых людей. Она вызывает многочисленные симптомы, включая покалывание, усталость, мышечные спазмы, когнитивные расстройства и нервно - психические расстройства. Это заболевание значительно ухудшает качество жизни (QoL), и этот аспект общего функционирования обеспечивает ценную информацию об эффективности лечения и благосостояния. Существует психологическая помощь, которая может улучшить QoL, но ее количество ограничено. Поэтому поиск новых методов, которые были бы как можно б

European Code Against Cancer, 5th edition - occupational exposures and cancer.

Occupational exposure to cancer-causing agents is a major, yet preventable, contributor to cancer in Europe and globally. In the European Union (EU), cancer is responsible for nearly half of all work-related deaths, underscoring the critical need for prevention measures. Effective strategies typically involve regulatory and workplace measures aimed at reducing or eliminating exposure risks. Raising awareness of hazardous workplace exposures is essential to empower individuals, foster a culture of prevention, and support effective regulation. The 5th edition of the European Code Against Cancer

Консолидация, систематическая оценка и сопоставление руководящих рекомендаций в отношении лечения хронической боли: Протокол для составления карты рекомендаций в отношении цифрового хронического заболевания.

ВВЕДЕНИЕ: Хроническая боль 1 В 5 :: взрослые и дети во всем мире; однако управление попрежнему носит весьма различный характер, и, как правило, обеспечивается низкий уровень медицинского обслуживания. Несогласованность рекомендаций, содержащихся в руководящих принципах клинической практики в отношении лечения хронической боли, способствует неоптимальному лечению пациентов. Мы будем разрабатывать и распространять живую цифровую карту рекомендаций в отношении хронической боли (e-Chronic Bain RecMap) для выявления заслуживающих доверия рекомендаций в three высокоприоритетные области1) опиоиды,2)

Clinical trial challenges, design considerations, and outcome measures in rare CNS tumors.

Clinical research for patients with rare cancers has been very challenging. First and foremost, patient accrual to clinical trials typically requires a network, cooperative group, or even international collaboration in order to achieve the necessary numbers of patients to adequately evaluate a new treatment or intervention. Similar limitations in preclinical models and in the understanding the natural history of the disease or pertinent prognostic factors further impede the development of hypothesis-based, appropriately powered clinical trials. However, despite these challenges, several studie

Просветительская работа с пациентами с помощью массового открытого онлайнового курса (МООК) для пациентов с множественными миеломами и лиц, обеспечивающих уход: описывающее исследование знаний, проведенное Французской ассоциацией пациентов с множественными миеломами (АФ3М) и французскоязычной межгруппой " Миэлома " (МФМ).

Множественная миелома (ММ) представляет собой хроническую гематологическую халатность, характеризующуюся сложными терапевтическими стратегиями, неоднократными рецидивами и существенными информационными и психосоциальными потребностями. Достижения в области пероральной терапии и амбулаторного лечения переложили бóльшую ответственность на пациентов и лиц, обеспечивающих уход, подчеркнув необходимость наличия доступных и высококачественных образовательных ресурсов. Терапевтическое просвещение пациентов (ТПЭ) направлено на то, чтобы помочь пациентам лучше понять свое состояние и более эффективно с

Cali cancer registry methods.

BackgroundThe Population Cancer Registry of Cali (RPCC) has operated since 1962, disseminating high quality information to provide a framework to assess and control the burden of cancer in Cali.MethodsThe collection of new cancer cases in permanent residents of Cali is done through active search in and notification from hospitals, and public and private laboratories. The Secretary of Municipal Public Health provides individual information on general mortality and death from cancer. Tumors are coded with ICDO-3 and mortality with ICD-10. Presented rates are standardized by age and trends are as

Using journey mapping to understand the experience and need for patients with chimeric antigen receptor T-cell therapy.

ObjectiveTo map the journey and needs of patients receiving chimeric antigen receptor T-cell (CAR-T) therapy, providing a reference for improving the comprehensive management of patients receiving clinical CAR-T cell therapy, as well as enhancing patients' overall well-being.MethodsA qualitative grounded theory approach was used. From August 2024 to January 2025, patients receiving CAR-T cell therapy at a university hospital in Wuhan, China, were enrolled through purposive sampling. The research data were collected from descriptive observation, focused observation, and selective observation. T

Familial aspects of fear of cancer recurrence: current insights and knowledge gaps.

Fear of cancer recurrence is fear or worry about cancer recurrence or progress. Fear of recurrence can impact patients' quality of life and wellbeing. Cancer survivors' families support them practically and emotionally, making them a vital supplement for official healthcare. Given the well-established important role of the family in dealing with cancer, we compiled the studies that examined the relationship between family-related factors and fear of cancer recurrence (FCR) among cancer survivors (CSs). One of the foremost studies in this field is the FCR model presented by Mellon and colleague

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… Applying social network analysis to identify the social support needs of adolescent and young adult cancer patients and survivors . J. Adolesc. Young Adult Oncol. 7 , 181 – 186 . doi: 10.1089/jayao.2017.0058 , PMID: 29106316 Lai W. S. Shu B. C. Hou W. L. ( 2019 ). …

Routes of administration, reasons for use, and approved indications of medical cannabis in oncology: a scoping review.

INTRODUCTION: Some patients diagnosed with cancer use medical cannabis to self-manage undesirable symptoms, including nausea and pain. To improve patient safety and oncological care quality, the routes of administration for use of medical cannabis, patients' reasons, and prescribed indications must be better understood. METHODS: Based on the Joanna Briggs Institute guidelines, a scoping review was conducted to map the current evidence regarding the use of medical cannabis in oncological settings based on the experiences of patients diagnosed with cancer and their healthcare providers. A searc