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Cancer Pain Is Not One-Size-Fits-All: Evolving from Tradition to Precision.

Cancer pain remains a significant challenge in oncology, profoundly affecting patients' quality of life, function, and prognosis. Historically under-recognized and managed with a uniform, opioid-centric approach, cancer pain was often inadequately treated. Advances in pain assessment, multimodal analgesia, and supportive care have improved outcomes, yet traditional algorithms frequently fail to address the complex, heterogeneous nature of cancer pain. Contemporary management is shifting toward precision and personalized medicine, integrating genetic, molecular, and biomarker data with individu

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… Integrative Therapies for Cancer Pain Integrative therapies such as acupuncture, hypnosis, massage, yoga and mindfulness-based therapies have shown efficacy in multimodal pain management in various randomized controlled trials. … Massage may be offered to patients experiencing pain during palliative and hospice care. 6. …

Supportive care needs of adults living with a peripherally inserted central catheter (PICC) at home: a qualitative content analysis.

BackgroundPeripherally inserted central catheters (PICCs) are common vascular access devices inserted for adults undergoing intravenous treatment in the community setting. Individuals with a PICC report challenges understanding information and adapting to the device both practically and psychologically at home. There is a lack of research investigating the supportive care needs of individuals with a PICC to inform nursing assessment and the provision of additional supports they may require to successfully adapt to life with a PICC. The aim of this study was to identify the supportive care need

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… One participant continued work as a massage therapist and indicated that they were required to spend time modifying how they provided a massage to protect the PICC. … ‘I’m still working for a living and I’m a massage therapist … you have to approach something from a slightly different angle, like you pick up limb that you want to work on and you can’t sort of wrap your arm around it like you used to sort of thing so, you know, you can attack other people from different …

Non-surgical treatment for lower limb apophyseal injuries.

RATIONALE: Lower limb apophyseal injuries are common in children and adolescents. The most common are traction apophysitis of the tibial tub … ators were poorly described but included exercise, stretches, nonsteroidal anti-inflammatories, and massage. SYNTHESIS OF RESULTS: Pharmaceutical intervention versus placebo for children with traction apophysitis of the tibial tubercle Compared to placebo, the evidence is very uncertain about the effects of dexamethasone on overall pain (MD -0.52, 95% CI …

Abstracts From JADPRO Live 2019: Washington State Convention Center • Seattle • October 24-27.

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… This study sought to examine how complementary and alternative medicine (CAM), specifically massage, yoga, meditation, and acupuncture, impact quality of life for patients receiving outpatient chemotherapy. … AP providers utilized a multi-modal approach to treat chronic pain, which included physical therapy, psychiatry, orthopedics, integrative medicine, acupuncture, massage, and social work. …

Neurophysiological Mechanisms Related to Pain Management in Bone Tumors.

BackgroundPrimary and metastatic bone tumor incidence has increased in the previous years. Pain is a common symptom and is one of the most important related factors to the decrease of quality of life in patients with bone tumor. Different pain management strategies are not completely effective and many patients afflicted by cancer pain cannot be controlled properly. In this sense, we need to elucidate the neurophysiology of cancer-induced pain, contemplating other components such as inflammation, neuropathies and cognitive components regarding bone tumors, and thus pave the way for novel thera

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… therapeutic exercise, occupational therapy, hydrotherapy, treatment for specific disorders), Psychological (psychoeducational interventions, cognitive behavioral therapy, relaxation therapy, hypnosis, guided imagery), Neurostimulation (transcutaneous, transcranial, implanted), and Integrative (acupuncture, massage … Manipulation, soft tissue manipulation, heat, and massage have been reported to reduce discomfort in these patients [ 100 ]. Psychological Cognitive behavioral therapy (CBT) refers to a broad range of treatments that aim to address maladaptive thinking, resulting in improved mood and behavior. …

Разоблачение множественных миеломы: важность подозрения в совершении злодеяний при атипичной хронической болезни, имитирующей дегенеративные условия.

Для пациентов с атипичной хронической болью необходима повышенная клиническая бдительность в отношении множественной миеломы. Симптомы могут перекликаться с дегенеративными мускулоскелетными условиями, что часто приводит к неправильному диагностике. Это подчеркивает необходимость проведения тщательной оценки в тех случаях, когда симптомы отклоняются от традиционных методов лечения, с тем чтобы содействовать своевременному диагностированию и эффективному регулированию злоумышленничества.

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… Complementary therapies like acupuncture, massage, and reflexology alleviate pain, reduce anxiety, and enhance well‐being, as endorsed by the Society for Integrative Oncology and the American Society of Clinical Oncology (ASCO) [ 9 ]. …

Managing emotional and physical stress in sickle cell anemia: a review of effective strategies and approaches.

Sickle cell anemia (SCA) is a genetic blood disorder characterized by recurrent pain episodes, chronic complications, and significant emotional and physical stress. This review article explores effective strategies for managing both the emotional and physical aspects of stress in SCA patients. A comprehensive literature search was conducted across multiple databases, including PubMed, Scopus, and Google Scholar, using keywords such as "sickle cell anemia", "stress management", "psychological support", and "pain management". Emotional stress in SCA arises from chronic pain, frequent hospitaliza

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… Techniques such as acupuncture, massage therapy, and mindfulness-based stress reduction (MBSR) offer additional avenues for pain relief and stress management. … Techniques such as acupuncture, massage therapy, and aromatherapy can provide symptomatic relief and enhance the effectiveness of conventional treatments. These therapies work by targeting pain pathways, reducing muscle tension, and promoting relaxation. …

Exploring the impact of a decision support algorithm to improve clinicians' chemotherapy-induced peripheral neuropathy assessment and management practices: a two-phase, longitudinal study.

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) negatively affects physical function and chemotherapy dosing, yet, clinicians infrequently document CIPN assessment and/or adhere to evidence-based CIPN management in practice. The primary aims of this two-phase, pre-posttest study were to explore the impact of a CIPN clinician decision support algorithm on clinicians' frequency of CIPN assessment documentation and adherence to evidence-based management. METHODS: One hundred sixty-two patients receiving neurotoxic chemotherapy (e.g., taxanes, platinums, or bortezomib) answered pati

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… Zakim Center for Integrative Therapies and Healthy Living at Dana-Farber Cancer Institute offers exercise, nutrition, yoga, acupuncture, massage, and mindfulness services. Fig. 1 Chemotherapy-Induced Peripheral Neuropathy Symptom Summary Report. … Zakim Center for Integrative Therapies and Healthy Living at Dana-Farber Cancer Institute offers exercise, nutrition, yoga, acupuncture, massage, and mindfulness services. …

Inpatient Medicine

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Chronic Non-cancer Pain Management and Addiction: A Review.

The use of opioids in chronic non-cancer pain (CNCP) has been a fast-rising treatment phenomenon in the last two decades. Though opioids are advocated in various chronic pain management guidelines, their use in chronic non-cancer pain still remains controversial as evidence of this approach is still weak. This paper highlights potential adverse effects associated with opioid use in pain management, including an increase in tolerance, dependence, and addiction outcomes. Nonetheless, opioids have an important place in contemporary CNCP management for selected patients. However, pain management m

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… These injections are augmented with other treatment approaches, including modification of analgesic medication, transcutaneous electrical nerve stimulation, aquatraining, massage therapy, and back education, among others [ 10 ]. …

Traditional chinese medicine in cancer care: a review of case series published in the chinese literature.

Traditional Chinese medicine (TCM) has been widely used in cancer in China. Case series report a series of cases exposed to a certain intervention. To understand the current situation of case series of TCM for cancer, we performed this review. We included case series of cancer patients treated with TCM therapy. Electronic searches were conducted in four main Chinese databases until February 2011. A total of 1,217 reports of case series (92,945 patients) were included. The top five types of cancer were lung cancer, liver cancer, stomach cancer, leukemia, and esophageal cancer. Leukopenia and hi

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… zhong_yi_yao ” (traditional Chinese medicine), “ zhong_cheng_yao ” (Chinese patent medicine), “ zhong_cao_yao ” (Chinese herbal medicine), “ zhen_ci ” (acupuncture), “ zhen_jiu ” (acupuncture and moxibustion), “ zhong_xi_yi_jie_he ” (integrated traditional Chinese and western medicine), “ an_mo ” (massage …

Характеристики самоидентифицированных сексуальных азартных игроков в клинике азартных заболеваний.

Фон и цели Исследования сексуального зависимости процветали в последний десятилетний период, стимулированные развитием большого количества онлайн-сексуальных активностей. Несмотря на накопление исследований, однако, доказательства, собранные в клинических образцах людей, ищущих лечение, остаются редкими. Целью этого исследования было описать характеристики (социodemографические, сексуальные привычки и сопутствующие заболевания) самоназначенных «сексуальных зависимых». Методы Образец составлял 72 пациента, обратившихся в поликлинический центр лечения по поводу своих сексуальных поведений. Данны

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… behavior is problematic Sexual behavior 71  Masturbating 100 31  Watching pornography 90.1 29.7  Using cybersex 77.5 43.6  Having multiple sexual partners 70.4 56  Searching sexual fantasies 49.3 40  Using sex toys 39.4 3.6  Having unprotected sexual intercourse 38 51.9  Using phone sex 38 29.6  Using sex massage …

Editorial: Cancer therapy: The challenge of handling a double-edged sword.

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… Interestingly, non-pharmacological interventions (mainly cryotherapy, compression therapy, and massage therapy) seemed to be more effective than pharmacological interventions (gabapentin, omega-3 fatty acids, vitamin E and N-acetylcysteine) in the 14 controlled trials that were eligible for the study …

Case report: Immune-mediated meibomian gland dysfunction following pembrolizumab therapy for advanced urothelial carcinoma.

Ocular immune-related adverse events are a relatively rare complication of immune checkpoint inhibitors. Common ocular toxicities range from dry eyes to inflammatory uveitis and ocular myasthenia gravis. Here, we present the case of a 55-year-old woman with recurrent urothelial carcinoma of the ureter after initially being managed with neoadjuvant cisplatin-based chemotherapy and surgical resection. She was treated with pembrolizumab which was complicated by immune-mediated pneumonitis after the eighth cycle, which was managed with a prolonged steroid course. The patient also developed red eye

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… Management was started with warm compresses, lid massages, oil-based eye drops, as well as dietary omega-3 fatty acid supplementation. With these measures, the patient had significant improvement in her eye symptoms. …

Burst of Corneal Dendritic Cells during Trastuzumab and Paclitaxel Treatment.

During breast cancer therapy, paclitaxel and trastuzumab are both associated with adverse effects such as chemotherapy-induced peripheral neuropathy and other systemic side effects including ocular complications. Corneal nerves are considered part of the peripheral nervous system and can be imaged non-invasively by confocal laser scanning microscopy (CLSM) on the cellular level. Thus, in vivo CLSM imaging of structures of the corneal subbasal nerve plexus (SNP) such as sensory nerves or dendritic cells (DCs) can be a powerful tool for the assessment of corneal complications during cancer treat

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… The ACM can be observed by slit-lamp examination after instillation of fluorescin into the conjunctival sac and a massage of the cornea on the surface of the corneal epithelium through the lids [ 20 ]. …

Who Needs What? Perceptions of Patients and Caregivers in Oncology Phase 1 Trials.

BackgroundThe study design and nature of oncology phase 1 clinical trials create a uniquely vulnerable patient population yet little research has been conducted to identify the added burden these trials create for both cancer patients and their caregiver(s).ObjectiveExamining the perceptions and needs of patients and their caregivers participating in phase 1 oncology clinical trials, the investigators tested the hypothesis that the caregiver will exhibit a higher level of burden and/or distress than the patient.MethodA mixed-methods exploratory process utilizing patient and caregiver interview

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… They voiced the need for the caregiver to be offered the same type of reclining chairs in the treatment rooms, to have full access to support services such as free massages, and open discussions with the medical team. …

Effects of combinations of diagnostic and treatment strategies for postpartum haemorrhage: a network meta-analysis.

RATIONALE: Postpartum haemorrhage (PPH) is a major cause of maternal mortality worldwide. The combination of accurate diagnosis and effectiv … ss ≥ 300 mL to < 500 mL plus abnormal observations, or 3. blood loss ≥ 500 mL) plus MOTIVE (uterine Massage, Oxytocics, Tranexamic acid, IntraVenous fluids, and Examination and Escalation of care) treatment bundle; 2-option trigger PPH diagnosis with calibrated drape (1. clinical concern, or 2. blood loss ≥ 500 mL) plus MOTIVE treatment bundle; calibrated …

Ginseng for the Management of Cancer-Related Fatigue: An Integrative Review.

BackgroundCancer-related fatigue (CRF) is one of the most prevalent, debilitating symptoms affecting a majority of patients with cancer worldwide. It can lead to poor compliance with anticancer therapy and discontinuation of treatment. Current management strategies for CRF center around activity and exercise; however, these strategies can be challenging for many patients undergoing active treatment. Ginseng has been shown to improve CRF and may provide benefit for patients suffering from CRF.MethodsA systematic review was completed by searching PubMed and Scopus databases.Results115 search res

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… Complementary therapies such as tai chi, yoga, acupressure, massage therapy, and cognitive behavior therapy have been researched; however, rigorous data are lacking and early findings have yet to be replicated ( Arring et al., 2019 ). …

Characteristics and advances in signaling pathways, cellular communication, cell junctions, and oxidative stress in lymphedema.

Lymphedema is a chronic inflammatory disease without an effective treatment method, and it results in a high disease burden and psychological distress in patients. Although there have been significant advances in targeted therapies, there are still no effective options to treat this refractory disease. In recent years, new advances and breakthroughs have been made in signaling pathways, including RAS/MAPK, PI3K/AKT, VEGF-C/VEGFR-3, HGF/MET, and TGF-β1, which are important for understanding the pathogenesis and disease progression of lymphedema. Mutations in genes encoding cell junctions affect

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… Most current lymphedema treatments include massage, manual lymphatic drainage, compression bandages, therapeutic exercise, and dietary intervention ( Shimizu et al., 2023 ). However, there is still a lack of targeted therapies for lymphedema, and there are no treatments based on molecular targets. … , bacterial | Cancer treatment: Surgery, radiotherapy (Western prevalence) | Regional hotspots: India (40% global filariasis burden) Epidemiology | Rare | Filarial: 250 endemic districts in India Cancer-related: 21%–28% breast cancer survivors (West), 75% gynecological malignancies Core Therapies | Massage …

Resilience and Sub-optimal Social Determinants of Health: Fostering Organizational Resilience in the Medical Profession.

The relationship between social determinants of health (SDOH) and resilience has been investigated at the individual level and, to some extent, at the community level. The aftermath of the COVID-19 pandemic further highlighted the necessity for organizational resilience in the United States. The US public health and health care system began the lengthy process of identifying the resiliency needs of its workforce that expand beyond disaster preparedness. The purpose of this article is to describe the relationship between resilience and SDOH and how medical training can infuse resiliency within

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… This emphasis on systemic changes as important foundational aspects of individual and workforce wellness is an encouraging sign that the superficial emphasis on an individual's path to wellness (often with “token” offers such as chair massages, meditation sessions, lunch break yoga, and “surprise” gifts …