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The BirthPlace collaborative practice model: results from the San Diego Birth Center Study.

Objective: The search for quality, cost-effective health care programs in the United States is now a major focus in the era of health care reform. New programs need to be evaluated as alternatives are developed in the health care system. The BirthPlace program provides comprehensive perinatal services with certified nurse-midwives and obstetricians working together in an integrated collaborative practice serving a primarily low-income population. Low-risk women are delivered by nurse-midwives in a freestanding birth center (The BirthPlace), which is one component of a larger integrated health

Сила мышц тазового пола у женщин с множественным склерозом и его связь с недержанием мочевого слоя и качеством жизни.

Множественный склероз (MS) является изнурительным аутоиммунным заболеванием, от которого в основном страдают женщины. ЦЕЛИ: В этом исследовании мы провели оценку зависимости между мышцами таза и недержанием мочевых мускулов и качеством жизни у женщин с MS. МАТЕРИАЛЫ И МЕТОДЫ: В этом междисциплинарном исследовании было принято на работу 87 женщин с НР. Данные, собранные с использованием демографического вопросника, Международного консультативного совещания по вопросу о краткой форме вопросника о несоблюдении - внутреннем несостоянии (ICIQ-UI SF) и Вопросника о качестве жизни (QOL-SF-36). Для из

Повышение уровня информированности и знаний о раке в Йоханнесбурге и округах iLembe с помощью целенаправленных просветительских мероприятий на уровне общин: экспериментальное исследование.

В Южной Африке рак по-прежнему вызывает все большую озабоченность в области общественного здравоохранения, особенно в недостаточно обслуживаемых общинах, где различия в уровне информированности и доступе к медицинскому обслуживанию приводят к задержкам в диагностике. В рамках этого исследования была проведена оценка воздействия ориентированной на культурные особенности просветительской деятельности на основе адаптированного модуля исследований и просвещения по вопросам доступа к информации о раковых заболеваниях (c-CARE) в районах Йоханнесбурга и iLembe. Было проведено экспериментальное исслед

Совпадение в полном тексте источника
… (Select all that apply) Irregular vaginal bleeding—Yes | 129 | 82.2 | 132 | 84.1 | 0.002 Ongoing lower back pain—Yes | 65 | 41.4 | 101 | 64.3 | 0.002 Abnormal or smelly vaginal discharge—Yes | 106 | 67.5 | 135 | 86 | <0.001 Pain during sex—Yes | 99 | 63.1 | 136 | 86.6 | <0.001 Heavier or longer menstrual … The proportion of participants identifying abnormal or smelly vaginal discharge increased from 67.5% to 86.0% ( p < 0.001), while recognition of pain during sex increased from 63.1% to 86.6% ( p < 0.001). …

The 48th Annual Meeting of the European Society for Blood and Marrow Transplantation: Nurses Group - Poster Sessions (NP001 - NP054).

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2021 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Las Vegas, Nevada, 31 August–3 September 2021: Video Loops

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Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology.

Vulvar cancer (VC) is a specific form of malignancy accounting for 5-6% of all gynaecologic malignancies. Although VC occurs most commonly in women after 60 years of age, disease incidence has risen progressively in premenopausal women in recent decades. VC demonstrates particular features requiring well-adapted therapeutic approaches to avoid potential treatment-related complications. Significant improvements in disease-free survival and overall survival rates for patients diagnosed with post-stage I disease have been achieved by implementing a combination therapy consisting of radical surgic

Novel diagnostic options for endometriosis - Based on the glycome and microbiome.

BackgroundEndometriosis is a chronic gynaecological disease whose aetiology is still unknown. Despite its prevalence among women of reproductive age, the pathology of the disease has not yet been elucidated and only symptomatic treatment is available. Endometriosis has high latency and diagnostic methods are both limited and invasive.Aim of reviewThe aim of this review is to summarise minimally invasive or non-invasive diagnostic methods for endometriosis and their diagnostic efficiencies. Furthermore, we discuss the identification and diagnostic potential of novel disease biomarkers of microb

Spontaneous uterine rupture after myomectomy in patients during pregnancy: Clinical cases in a single university center.

Uterine rupture is an infrequent yet sometimes fatal complication of a subsequent vaginal birth attempt following a previous uterine surgery. We have chosen to write about spontaneous uterine ruptures following myomectomy due to the scarcity of data on this subject, stemming from the limited number of reported cases. Furthermore, with the increasing trend of advanced maternal age, there is a growing cohort of pregnant women with a history of myomectomy, thereby presenting a timely opportunity to examine this phenomenon in greater depth. A total of 28 studies reporting pregnancies after prior m

Effectiveness of a pelvic floor muscle exercise program on urinary incontinence following childbirth.

UNLABELLED: EXECUTIVE SUMMARY: Objectives  The primary objective of this review was to determine, from the available evidence, the effectiveness of an antenatal and/or a post-natal program of pelvic floor muscle exercises (PFME) compared with usual care on preventing, reducing or resolving the incidence and severity of stress incontinence, urge incontinence or mixed stress and urge urinary incontinence following childbirth. Secondary objectives were included to examine the effectiveness of a PFME program on pelvic floor muscle strength and on encouraging adherence to an exercising program. IN

Воздействие дексаметазона на подстрекательские маркеры хирургического стресса: случайное испытание роботической истерэктомии.

Иммунодепрессивное действие дексаметазона может помочь уменьшить риск таких послеоперационных осложнений, как инфекция, образование сцепления и запоздалое исцеление ран. Дексаметасон может уменьшить повреждение тканей и ускорить восстановление, смягчив возбудительскую реакцию, модифицировав активность иммунных клеток и сократив высвобождение провоспалительных цитокинов. В этом первом произвольном эксперименте дексаметазона в роботизированной гистерэктомии мы стремились оценить его влияние на уменьшение C-реактивного белка (CRP) в качестве косвенного признака хирургического стресса. Methods Wom

Women with Gaucher Disease.

Gaucher disease is an inherited disorder in which there is a deficiency of the enzyme glucocerebrosidase, which leads to the accumulation of glucosylceramide. Although much scientific evidence is now available, there is still limited data on the impact on the different life stages of women with this disease. Among other alterations, a delay in menarche has been described, although it has not been related to fertility problems. Menorrhagia is relatively frequent, being related to the presence of thrombocytopenia, thrombocytopathies or coagulation disorders. On the other hand, pregnancy planning

Establishing the safety of waterbirth for mothers and their babies: the POOL cohort study with nested qualitative component.

BACKGROUND: Intrapartum water immersion analgesia has been recommended by the National Institute for Health and Care Excellence since 2007, but high-quality evidence relating to the safety of waterbirth for mothers and their babies was lacking. PRIMARY STUDY OBJECTIVE: To establish whether, in the case of 'low-risk' women who use water immersion during labour, waterbirth, compared to birth out of water, is as safe for mothers and their babies. METHODS: A cohort study with non-inferiority design. SETTING: Twenty-six National Health Service organisations in England and Wales. PARTICIPANTS: T

Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period.

BACKGROUND: Venous thromboembolism (VTE), although rare, is a major cause of maternal mortality and morbidity, and methods of prophylaxis are therefore often used for women considered to be at risk. This may include women who have given birth by caesarean section, those with a personal or family history of VTE and women with inherited or acquired thrombophilias (conditions that predispose people to thrombosis). Many methods of prophylaxis carry risks of adverse effects, and as the risk of VTE is often low, it is possible that the benefits of thromboprophylaxis may be outweighed by harms. Guide

Биология и болезни крыс

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Systematic review of patient-reported outcome item libraries in cancer research: an EORTC Quality of Life Group study.

BackgroundPatient-reported outcome (PRO) item libraries support flexible PRO assessment in cancer research by facilitating the development of customized item lists. However, little is known about the use of item lists in clinical research. This systematic review addresses this by assessing utilization of PRO item libraries and lists in oncology research.MethodsA systematic review of MEDLINE, Embase, and CINAHL identified cancer studies using PRO item libraries to develop item lists, regardless of study design, published between October 2021 and September 2025. Key features of item library usag

Ocrelizumab-Induced Hemophagocytic Lymphohistiocytosis: A Case Report.

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon disorder marked by severe immune system dysfunction and excessive inflammation. Its clinical features often mimic those of severe sepsis, including persistent high fevers, multiorgan failure, cytopenia, and coagulation abnormalities. HLH can be triggered by infections, malignancies, rheumatological disorders, genetic factors, and medications, particularly those that cause immunosuppression. Ocrelizumab, an anti-CD20 monoclonal antibody used in the treatment of multiple sclerosis, has been associated with rare immune-mediated complications

Clinical Manifestations of Human Exposure to Fungi.

Biological particles, along with inorganic gaseous and particulate pollutants, constitute an ever-present component of the atmosphere and surfaces. Among these particles are fungal species colonizing almost all ecosystems, including the human body. Although inoffensive to most people, fungi can be responsible for several health problems, such as allergic fungal diseases and fungal infections. Worldwide fungal disease incidence is increasing, with new emerging fungal diseases appearing yearly. Reasons for this increase are the expansion of life expectancy, the number of immunocompromised patien

Совпадение в полном тексте источника
… The main signs and symptoms include edema, erythema, paresthesia, pruritus, odorless vaginal discharge with a cottage cheese appearance, vulvodynia, dyspareunia, and dysuria [ 170 ]. …

Emergency Care

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Comparison of different concentrations of a povidone iodine-diluted sitz bath in the prevention of perianal infection in patients undergoing chemotherapy for hematological malignancy: study protocol for a randomized controlled trial.

BackgroundInfection is one of the most common causes of death in patients with hematological malignancies during chemotherapy. Due to its special location, local warmth and humidity, repeated pollution with stool and urine, and characteristically wrinkled anatomical structure within which bacteria can hide, the perianal becomes a site with a high incidence of infection. Such infection also has a high recurrence rate and high mortality, increasing the economic burden of patients, delaying the time of treatment and reducing the quality of life. In severe cases, sepsis occurs and endangers the pa

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