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Multidisciplinary Management of Morbidities Associated with Chronic Graft-Versus-Host Disease.

Chronic graft-versus-host disease (cGVHD) represents a common long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT). It imposes a significant morbidity burden and is the leading cause of non-relapse mortality among long-term HSCT survivors. cGVHD can manifest in nearly any organ, severely affecting the quality of life of a transplant survivor. While the mainstay of treatment has remained systemic immunosuppression with glucocorticoids, progress has been made within the last few years with approvals of three oral agents to treat steroid-refractory cGVHD: ibrutin

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… occurs more frequently in women than men, 85 and is characterized by vulvovaginal involvement (e.g., erosions, ulceration, adhesions, stenosis, fibrosis, lichen sclerosis) that can present as vulvar pain, vaginal dryness, dyspareunia, and post-coital bleeding, which can impair sexual function. 88,89 Gynecologists …

Fertility Preservation in Female Patients with Cancer. Part I: Challenges and Future Prospects in Developing Countries; A Narrative Review Study.

While international guidelines on oncofertility practice have been published in developed countries, there is limited information available on oncofertility practice in developing countries, which often face limitations in their cancer health support networks. As survival rates improve in the field of cancer and other diseases, there is a growing need for stronger oncofertility services in developing countries. Given that 50% of cancer patients are under the age of 65, many of these patients are of reproductive age and preserving their fertility health prior to starting treatment is valuable.

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… Azh N Noei Teymoordash S Ghaffari F Fertility preservation in endometrial cancer: current knowledge and practice J Obstet Gynecol Cancer Res 2022 7 5 362 373 14 Iliadis SI Gambadauro P Conservative management of earlystage endometrial cancer for fertility preservation: a survey study among Swedish gynecologists …

Review of Potential Barriers to Effective Hemostatic Management of Acquired Hemophilia A by Non-Hemophilia Experts in the United States.

Acquired hemophilia A (AHA) is an ultra-rare autoimmune disorder caused by autoantibodies against factor VIII. It often presents with life-threatening bleeding to non-hemophilia experts, who have limited awareness of this condition. This review evaluated hemostatic management and identified barriers to optimal management of AHA by non-hemophilia experts in the United States through a literature review. AHA case reports published by non-hemophilia experts from January 2016 through November 2021 in non-hematology journals were critically reviewed for a chronology of clinical course and managemen

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… Examples of non-hemophilia experts include emergency room physicians, obstetricians, gynecologists, and surgeons. …

Cancer in pregnancy: FIGO Best practice advice and narrative review.

Cancer during pregnancy is relatively rare. The incidence is underestimated due to the lack of international registries covering both high-income and low- and middle-income countries, and is expected to rise with increasing maternal age and increasing global adoption of cell-free DNA testing for aneuploidy. Physiological changes during pregnancy often make the diagnosis challenging and delayed. Lack of experience and knowledge about this condition may also contribute to late diagnosis, suboptimal management, and occasionally inadvertent fetal and/or maternal harm. The principles of cancer mana

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… Obstetricians ACo , Gynecologists , Practice CoO . Committee opinion no. 656: guidelines for diagnostic imaging during pregnancy and lactation. Obstet Gynecol. 2016;127(2):e75‐e80. 34. Sorouri K, Loren AW, Amant F, Partridge AH. Patient‐centered care in the management of cancer during pregnancy. …

Endodontics in Systemically Compromised Patients

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The State of Cancer Care in the United Arab Emirates in 2022.

Cancer is the third-leading cause of death in the United Arab Emirates (UAE); cancer care in the UAE has evolved dramatically over the last 40 years, from a single center in Al Ain in 1981 to more than 30 cancer centers and clinics across the UAE, with at least four comprehensive cancer centers in the UAE nowadays. Despite the significant progress in medical care, cancer quality control across the UAE is still lacking, with significant variations in cancer care across the cancer centers. Access to clinical trials is still hampered by a lack of expertise and research infrastructure and a small

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… General gynecologists and general surgeons operate on many women’s cancer cases. Currently, there are no dedicated gynecologic oncology units in the UAE. Moreover, the number of trained gynecologic oncology surgeons is very limited and is estimated to be less than ten across the UAE. …

Current Diagnosis and Management of Primary Chylomicronemia.

Primary chylomicronemia (PCM) is a rare and intractable disease characterized by marked accumulation of chylomicrons in plasma. The levels of plasma triglycerides (TGs) typically range from 1,000 - 15,000 mg/dL or higher.PCM is caused by defects in the lipoprotein lipase (LPL) pathway due to genetic mutations, autoantibodies, or unidentified causes. The monogenic type is typically inherited as an autosomal recessive trait with loss-of-function mutations in LPL pathway genes (LPL, LMF1, GPIHBP1, APOC2, and APOA5). Secondary/environmental factors (diabetes, alcohol intake, pregnancy, etc.) often

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… Clinicians across multiple disciplines, such as primary care physicians, gastroenterologists, gynecologists, and other doctors who have occasionally encountered severe HTG patients, should consult lipidologists concerning further diagnostic tests for chylomicronemia. …

Osteoporosis in Frail Patients: A Consensus Paper of the Belgian Bone Club.

In this consensus paper, the Belgian Bone Club aims to provide a state of the art on the epidemiology, diagnosis, and management of osteoporosis in frail individuals, including patients with anorexia nervosa, patients on dialysis, cancer patients, persons with sarcopenia, and the oldest old. All these conditions may indeed induce bone loss that is superimposed on physiological bone loss and often remains under-recognized and under-treated. This is of particular concern because of the major burden of osteoporotic fractures in terms of morbidity, mortality, and economic cost. Therefore, there is

Delayed gastric emptying in critical illness: is enhanced enterogastric inhibition with cholecystokinin and peptide YY involved?

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Molecular Mechanism and Prevention Strategy of Chemotherapy- and Radiotherapy-Induced Ovarian Damage.

Fertility preservation is an emerging discipline, which is of substantial clinical value in the care of young patients with cancer. Chemotherapy and radiation may induce ovarian damage in prepubertal girls and young women. Although many studies have explored the mechanisms implicated in ovarian toxicity during cancer treatment, its molecular pathophysiology is not fully understood. Chemotherapy may accelerate follicular apoptosis and follicle reservoir utilization and damage the ovarian stroma via multiple molecular reactions. Oxidative stress and the radiosensitivity of oocytes are the main c

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… Effective multidisciplinary oncofertility strategies involving a highly skilled and experienced team composed of medical oncologists, gynecologists, reproductive biologists, surgeons, patient care coordinators, psychologists, and research scientists should be carefully considered for each patient to …

Сексуальное здоровье после неврологических расстройств: всеобъемлющий обзор данных о лечении.

Предыстория/задачи: Сексуальная дисфункция (СД) и более широкие проблемы сексуального здоровья являются распространенными после неврологических расстройств, однако улики вмешательства разрознены по различным условиям и результатам. В ходе этого зонтичного обзора были собраны и оценены на систематической основе данные о мерах, направленных на УР и сексуальное здоровье неврологических групп населения, а также квалифицированные выводы с использованием достоверной информации. Методы: с момента создания были проведены обыски PubMed, Web of Science, Cochrane Bibrary, Embase, PsycINFO, EBCOCOhost и S

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… Interdisciplinary collaboration between neurologists, physiatrists, urologists, gynecologists, psychologists, sex therapists, physiotherapists, and nurses is likely crucial for implementation [ 48 , 49 , 50 , 51 , 52 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ]. …

Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions.

Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune modulation, and secondary dissemination to distant sites through a series of mechanisms, and it has been proved that lymph node metastasis (LNM) is an essential prognostic indicator in many different types of cancer. Therefore, it is important for oncologists to understand the mechanisms of tumor cells to metastasize to LNs, as well as how LNM affects the prognosis and therapy of patients with cancer in order to provide patients with accurate disease assessment and effective treatment strategies. In recent years

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… In addition to TNM staging, a specific staging system for gynecologic malignancies has been established by the Federation of International of Gynecologists and Obstetricians (FIGO). This FIGO staging system strongly emphasizes the significance of LN evaluation. …

Abstracts of the ICARE 2024 78th SIAARTI National Congress

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Abstracts from the 8th Drug Hypersensitivity Meeting (DHM)

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Резюме докладов 2017 Ежегодное совещание Общества общей внутренней медицины.

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Genomic innovations in cancer prevention, diagnosis, prognosis and precision therapeutics.

Cancer research has undergone a transformative change with the advent of high-throughput genomic technologies. Advances in next-generation sequencing accelerated the identification of somatic and germline alterations that drive tumorigenesis enabling the transition from traditional histology-based cancer classification to molecularly informed precision oncology. Large-scale sequencing initiatives and clinical genomic profiling facilitated the development of companion diagnostic assays and targeted therapies. Beyond targeted therapies, genomic innovations have also catalyzed the emergence of no

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… A particular hereditary cancer syndrome may be present in cases that obstetrician-gynecologists and other care providers frequently encounter such as ovarian, breast, colon, and endometrial cancer ( Hereditary Cancer Syndromes and Risk Assessment: ACOG COMMITTEE OPINION, 2019 ). …

UMIB Summit 2015

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Alcohol Misuse in Older Women: A Scoping Review of Correlates, Consequences, Treatment, and Prevention.

BackgroundAlcohol use and alcohol use disorder (AUD) among older women (defined as age 50 and over) have increased substantially in recent years. Compared to men and younger women, older women negotiate biopsychosocial transitions that put them at greater risk of alcohol-related health conditions as they age and are less reliably screened and treated for heavy alcohol use and AUD.ObjectivesThis scoping review represents a critical evaluation of research methodology and findings since 2004 on biopsychosocial correlates and consequences of alcohol misuse (i.e., heavy alcohol use, defined as four

Abstracts

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Всемирный конгресс по болезням остеопороза, остеоартрита и мускулоскелета 2025).

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