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Should patient eligibility criteria for cervical disc arthroplasty (CDA) be expanded? A retrospective cohort analysis of relatively contraindicated patients undergoing CDA.

BACKGROUND CONTEXT: Cervical disc arthroplasty (CDA) is a safe and effective alternative to anterior cervical discectomy and fusion (ACDF) i … nificant loss of disc height (between 50% and 75% of initial measurements or 1.5-3mm), (3) bridging osteophytes, and (4) prior cervical spine surgery based on preoperative cervical radiographs. The other cohort included patients without any relative contraindication who underwent CDA over the same time frame. Additionally, a subgroup analysis was used to com …

[Diagnosis and treatment of osteoporosis in patients with chronic kidney disease : Joint guidelines of the Austrian Society for Bone and Mineral Research (ÖGKM), the Austrian Society of Physical and Rehabilitation Medicine (ÖGPMR) and the Austrian Society of Nephrology (ÖGN)].

DEFINITION AND EPIDEMIOLOGY: Chronic kidney disease (CKD): abnormalities of kidney structure or function, present for over 3 months. Staging … ot be used for the diagnosis or monitoring of osteoporosis in the presence of aortic calcification, osteophytes or vertebral fracture (not graded). FRAX can be used to aid fracture risk estimation in all stages of CKD (1C). Bone turnover markers can be measured in individual cases to monitor treatment (2D). Bone biopsy may be considered in individual cases, …

The impact of patellofemoral joint diseases on functional outcomes and prosthesis survival in patients undergoing unicompartmental knee arthroplasty: a systematic review and meta-analysis.

BACKGROUND: Patellofemoral joint (PFJ) diseases are chronic degenerative conditions that contribute to knee joint symptoms. Unicompartmental … survival. However, severe lateral PFJ degeneration, lateral patellar subluxation, lateral trochlear osteophytes, and patellar bone marrow edema did influence results. Fifteen high-quality studies were included in the meta-analysis, involving 6080 patients-1338 in the PFJ disease group and 4,742 in the non-PFJ disease group. With an average NOS score of 7.2, …

A radical procedure of circumferential spinal cord decompression through a modified posterior approach for thoracic myelopathy caused by severely impinging anterior ossification.

BACKGROUND CONTEXT: Thoracic myelopathy caused by an anterior, massive ossified plaque is often progressive and responds poorly to conservat … man who presented with severe thoracic myelopathy resulting from anterior impingement with multiple osteophytes is described as an illustrative patient. RESULTS: The sites of ossification in this series were distributed widely, from T4-T12. The anterior ossified plaques of all patients were resected completely. Five patients who had intraoperative evidence …

[Hyperextension trauma in patients with cervical spondylosis].

PURPOSE OF THE STUDY To evaluate retrospectively a group of patients with hyperextension injury to the cervical spine who were treated at th … gical management, in most of the cases from the anterior approach, which allows us to remove dorsal osteophytes and perform careful decompression to prevent damage to nerve structures and to preserve those which are still intact. There was no significant difference in the outcome between urgent and delayed trauma management, which is unusual amongst other in …

Joint manifestations revealing inborn metabolic diseases in adults: a narrative review.

Inborn metabolic diseases (IMD) are rare conditions that can be diagnosed during adulthood. Patients with IMD may have joint symptoms and the challenge is to establish an early diagnosis in order to institute appropriate treatment and prevent irreversible damage. This review describes the joint manifestations of IMD that may be encountered in adults. The clinical settings considered were arthralgia and joint stiffness as well as arthritis. Unspecific arthralgias are often the first symptoms of hereditary hemochromatosis, chronic low back pain may reveal an intervertebral disc calcification in

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… X-rays show geodes encircled by condensation and positioned in the subchondral bone area, osteophytes with rounded edges or hook-like osteophytes, joint space narrowing as well as chondrocalcinosis of wrists, hips and knees joints [ 17 ]. … X-rays show joint damage with joint space narrowing, osteophytes, subchondral sclerosis, subchondral geodes, periarticular osteopenia. Pyrophosphate arthropathy can occur in some cases [ 64 , 65 ]. …

The Advantages of Radiofrequency Echographic MultiSpectrometry in the Evaluation of Bone Mineral Density in a Population with Osteoarthritis at the Lumbar Spine.

BACKGROUND: Osteoarthritis (OA) in the lumbar spine can potentially lead to an overestimation of bone mineral density (BMD), and this can be a challenge in accurately diagnosing conditions like osteoporosis, where precise measurement of BMD is crucial. Radiofrequency Echographic Multi Spectrometry (REMS) is being recognized as an innovative diagnostic tool for assessing bone status. The purpose of this study was to evaluate whether the use of REMS may enhance the identification of osteoporosis in patients with osteoarthritis. METHODS: A cohort of 500 patients (mean age: 63.9 ± 11.2 years) dia

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… The authors interpreted the results using the Kellgren and Lawrence grading scale (K-L) for OA without assessing joint space narrowing and osteophytes separately [ 24 ]. K-L grades range from 0 to 4. … On the other hand, it is important to underline how the alterations induced by spinal osteoarthritis (osteophytes, facet sclerosis) can shield osteoporosis, consequently leading to misinterpretation of BMD [ 4 ]. …

[Safety study of navigation-assisted medial "in-out-in" technique in C2 screw fixation].

Objective: To evaluate the safety and clinical efficacy of the navigation-assisted medial "in-out-in" technique in C2 pedicle screw fixation … test were used for data comparison. Results: Six patients with reduction blocked by atlanto-dental osteophytes first underwent anterior cervical atlanto-dental arthroplasty, followed by posterior surgery in the prone position, while the remaining 62 patients underwent posterior reduction and internal fixation. All 36 patients in the navigation group success …

Arthroscopic debridement for osteoarthritis of the elbow: Results and analysis of predictive factors.

INTRODUCTION: Osteoarthritis is the second most frequent cause of elbow stiffness, after trauma sequelae. Surgical treatment mainly consists … accident/occupational disease status) and radiographic factors (foreign bodies, joint impingement, osteophytes, and fossa filling) was also assessed. RESULTS: The series comprised 87 patients: 75 male (86.2%); mean age, 49 years (range, 18-73 years). Arthroscopic debridement significantly improved all functional scores at a minimum 6 months, and notably th …

Comparison of clinical and radiographic outcome in instrumented anterior cervical discectomy and fusion with or without direct uncovertebral joint decompression.

BACKGROUND CONTEXT: Anterior cervical discectomy and fusion (ACDF) is an established procedure for the operative treatment of cervical disc disease in patients with radiculopathy resulting from impingement from uncovertebral joint osteophytes. Studies demonstrate that direct decompression of the lesion provides good result. However, known complications include vertebral artery injury, dural tears, nerve root injury, loss of biomechanical stability and increased operative time. Other studies suggest that disc space distraction may play an important role by indirectly decompressing neural elemen…

Histone modifications: Unveiling the epigenetic enigma of degenerative skeletal diseases.

Degenerative skeletal diseases, including osteoporosis, osteoarthritis, and intervertebral disc degeneration, are prevalent age-related conditions characterized by progressive tissue degeneration and functional decline. Histone modifications are covalent modifications of histone residues, catalyzed by specific enzymes, that modulate chromatin architecture and transcriptional activity. Accumulating evidence highlights the critical involvement of histone modifications in orchestrating disease-associated transcriptional programs. In osteoporosis, histone modifications regulate osteoblast and oste

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… Intra-articular overexpression of KDM6A in mice led to pronounced osteophyte formation and increased osteophyte volume around the injured knee, whereas KDM6A knockout alleviated OA features, including cartilage loss, osteophyte development, and subchondral trabecular bone loss [ 188 , 215 ]. … Lian et al. demonstrated that subchondral mesenchymal stem cells (SMSCs) from OA knees possess higher osteogenic and chondrogenic potential than bone marrow–derived MSCs, contributing to subchondral bone over-mineralization and osteophyte formation. …

A new four-area method for evaluating biochemical changes in lumbar facet joint degeneration on T2* mapping.

PURPOSE: To investigate the diagnostic efficacy of a new four-area method for evaluating biochemical changes in lumbar facet joint (LFJ) degeneration on T2* mapping. METHODS: LFJ degeneration was morphologically graded on T2-weighted imaging using the Weishaupt system. T2* value of LFJ was measured on T2* mapping using both all-inclusive and four-area methods. Inter-observer reliability for continuous and categorical variables was evaluated using intraclass correlation coefficient (ICC) and Kappa value, respectively. The correlation between continuous variables and ordered categorical variabl

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… LFJ degeneration was morphologically graded on T2-weighted imaging using the Weishaupt system [ 17 ]: grade 0, normal facet joint space (2–4 mm width); grade 1, mild degenerative disease, narrowing of the facet joint space (< 2 mm) and/or small osteophytes and/or mild hypertrophy of the articular process … ; grade 2, moderate degenerative disease, narrowing of the facet joint space and/or moderate osteophytes and/or moderate hypertrophy of the articular process and/or mild subarticular bone erosions; and grade 3, severe degenerative disease, narrowing of the facet joint space and/or large osteophytes and …

Spatiotemperal Dynamics of Osteoarthritis: Преобразование значений от стенда до Бедсайда.

Остеоартрит (OA) представляет собой многогранное дегенеративное совместное расстройство, вызванное различными факторами риска, такими, как возраст, механический стресс, воспаление и метаболическое воздействие. Эти элементы способствуют его разнообразным фенотипам и эндотипам, что подчеркивает имманентную сложность болезни. Участие нескольких тканей и их взаимодействие еще больше осложняет расследование ОА. Нынешние ограничения в области технологий пространственного фенотификации в сочетании со сложной сетью многофакторных взаимодействий препятствуют обнаружению надежных ранних диагностических

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… In the final stage, significant deformation of the joint surface occurs due to continued bone microfractures and reparative changes, including the formation of osteophytes. These osteophytes and fibrocartilaginous proliferation contribute to altering joint contour and function. … There is heightened recruitment of MSCs, which accelerates osteoblast differentiation and fosters osteophyte formation, contributing to joint deformity. …

Severe Disc degeneration is associated with lower caudal subendplate hounsfield unit values in degenerative lumbar spinal stenosis.

STUDY DESIGN: Retrospective radiological analysis OBJECTIVE: To analyze the distribution of computed tomography (CT)-based Hounsfield unit (HU) values of lumbar vertebrae and explore the correlation between HU values and the modified Pfirrmann grades in patients with degenerative lumbar spinal stenosis (DLSS). METHOD: A total of 82 DLSS patients were divided into two gender-based groups for this retrospective analysis. Demographic data, including age, gender, body mass index, medical history, smoking status, operative levels, bone turnover markers (BTMs), and bone metabolism indicators, of al

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… Among these, dual-energy x-ray absorptiometry (DXA) is considered to be the gold standard for measuring bone mineral density (BMD); however, DXA results of elderly people are often inaccurate due to the presence of lumbar osteophytes [ 3 ]. … Quantitative computed tomodensitometry (qCT) demonstrates superior ability in distinguishing between cancellous and cortical bones, providing more accurate BMD results in elderly patients with scoliosis, obesity, aortic calcification, or osteophytes. …

Disorders of the Spinal Cord

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… Causes and Pathophysiology Osteophyte production occurs in response to degenerative changes in the intervertebral discs. The changes may be secondary to aging and trauma. … Diagnosis Diagnosis is based on radiographic identification of osteophyte formation on the ventral surface (in the region of the metaphysis) of the vertebral body or bodies. Osteophytes may occur at either normal or narrowed disc spaces. …

Charcot Arthropaticy of the Peelter with Ipsionteral Wrist и First Carpometakarpal Shiri Malformation I Type with Syringomyelia.

Артропатия плеча является редким проявлением нервно - суставной болезни и чаще всего ассоциируется с шприцомелией. Когда это происходит, оно часто приводит к постепенному совместному разрушению, но из-за минимальной боли оно приводит к задержкам в диагностике. Мы сообщаем о случае 54-летней женщины, представлявшей трехмесячную историю опухоли левого плеча, деформации и жесткого ограничения диапазона движения, связанного с ипсиосторонней деформацией запястья. У пациента была известная история неправильной формы Кьяри первого типа с шприцомелией. В ходе клинического обследования была выявлена за

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… Early osteophytic changes were additionally noted at the ipsilateral radial head (Figure 3 ). … Lateral radiograph of the left elbow demonstrating early degenerative and neuropathic changes, including radial head osteophyte formation and mild articular surface irregularity, suggestive of early ipsilateral joint involvement. …

Chronic Pain and Bone-Related Pathologies: A Narrative Review.

PurposePain related to bone may occur as a result of trauma, bone fracture, genetic disease, arthritis, benign or malignant primary bone tumors and bone cancer metastases. We discuss the pathophysiology of chronic bone-related pain, treatment options and therapeutic perspectives.MethodsUsing predefined terms, we searched PubMed, MEDLINE, and Google Scholar for meta-analyses, evidence-based reviews, and clinical practice guidelines. This narrative article reviews pathologies linked to chronic bone pain and discusses the preventive and therapeutic strategies for better bone pain management.Resul

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… Osteophyte formation, subchondral bone change, synovitis, inflammation. Rheumatoid arthritis Spondyloarthritis Psoriatic arthritis | Chronic autoimmune inflammatory disease. Cartilage and bone damage. … It is characterized by focal areas of articular cartilage loss in synovial joints, associated with varying degrees of osteophyte formation, subchondral bone change and synovitis. …

Accuracy and potential risk factors of pedicle screw placement using a noninvasive-registration robotic system in the thoracolumbar spine.

To evaluate the accuracy of screw placement using the ORTHBOT robotic system in degenerative spine surgeries at our institution and identify … so increased the risk of screw displacement (P < 0.01), as more severe degeneration, with increased osteophyte formation and higher cortical bone density, may increase the difficulty of K-wire insertion, leading to displacement on the facet joint surface. Age did not have a significant impact on screw accuracy (P = 0.028). This study conducted a retrospectiv …

Utility of REMS-Derived Fragility Score and Trabecular Bone Score in Evaluating Bone Health in Type 2 Diabetes Mellitus.

Background/Objectives: A significantly higher fracture risk characterizes Type 2 diabetes mellitus (T2DM) patients when compared to the non-diabetic population, even though their average bone mineral density (BMD) tends to be normal or high. This elevated risk is primarily driven by defective bone quality. The trabecular bone score (TBS) and radiofrequency echographic multispectrometry (REMS) have recently been proposed to improve the assessment of bone quality in T2DM individuals. This study aimed to evaluate whether TBS and REMS can improve the identification of osteoporosis and fracture ris

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… The discrepancy between REMS and DXA measurements may be explained, at least in part, by the ability of REMS to eliminate artifacts commonly observed in patients with T2DM, such as osteophytes, degenerative joint changes, vascular calcifications, and diffuse idiopathic skeletal hyperostosis, which typically … Since TBS is derived from lumbar spine DXA images, it is inherently subject to the same sources of error and artifacts that affect BMD measurements, including degenerative spinal changes, osteophytes, and vascular calcifications. …

Tips for Successful Ulnar Collateral Ligament Reconstruction.

BACKGROUND: Ulnar collateral ligament (UCL) reconstruction has become an increasingly common procedure in overhead-throwing athletes because … ubercle, the ulnar ridge approximates the center of the tubercle.Failure to resect medial olecranon osteophytes can result in continued elbow pain. Preoperative computed tomography can help in identifying any notable osteophytes.Begin drilling the humeral tunnel with use of a small, sharp-tipped drill, such as a 3.5-mm drill, which will allow you to precisel …