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Trauma echoes: factors associated with peritraumatic distress and anxiety five days following Iranian missile attack on Israel.

Introduction: On 13-14 April 2024, Iran launched ∼300 drones and missiles at Israel, in an unprecedented attack. As most studies examine the effects of trauma months or years later, less is known about its effects days later. To fill this gap, this study gauged the population response, five days after the attack. Specifically, we examined the prevalence and factors associated with two precursors for later development of PTSD, peritraumatic distress (PD) and generalized anxiety disorder (GAD).Methods: Five-hundred and fifty-three participants (Mage = 57.51, SD = 13.67 years, range [30-90], 48.3

Risk for Anaphylactic Reaction from Cardiac Catheterization in Patients Receiving β-Adrenergic Blockers or Angiotensin-Converting Enzyme-Inhibitors.

BACKGROUND: β-Adrenergic blockers (BBs) have been associated with increased risk for severe anaphylactic reaction (AR) from contrast media; however, this was shown with intravenous contrast media, before widespread use of low osmolar contrast media, angiotensin-converting enzyme-inhibitors (ACE-Is), and cardioselective BBs. OBJECTIVE: To assess the risk for AR during cardiac catheterization (CC) associated with BB or ACE-I exposure. METHODS: Patients who experienced adverse reactions during CC from January 2004 to December 2013 were identified; 1 to 2 matched controls were assigned for each

Effects of violent and nonviolent sexualized media on aggression-related thoughts, feelings, attitudes, and behaviors: A meta-analytic review.

Women are often depicted as sex objects rather than as human beings in the media (e.g., magazines, television programs, films, and video games). Theoretically, media depictions of females as sex objects could lead to negative attitudes and even aggressive behavior toward them in the real world. Using the General Aggression Model (Anderson & Bushman, 2002) as a theoretical framework, this meta-analytic review synthesizes the literature on the effects of sexualized media (both violent and nonviolent) on aggression-related thoughts, attitudes, and behaviors. Our sample includes 166 independent st

Social Media and Direct-to-Consumer Treatments in Pediatric and Young-Adult Patients With Alopecia: Variable Use and Mixed Perceptions.

BACKGROUND: Social media is a common source of health information for children and young adults, yet little is known about how young patient … though only 30% were current users. Perceived effectiveness was inconsistent. CONCLUSIONS: Social media exposure and marketing of DTC products appear to shape how youth approach alopecia management, although reported experiences were variable and often unsatisfactory. Dermatologists should inquire about online content exposure and DTC product use in clinical c …

Deletion of core septin gene aspB in Aspergillus fumigatus results in fungicidal activity of caspofungin.

Septins are a family of GTP-binding proteins found in many eukaryotic lineages. Although highly conserved throughout many eukaryotes, their functions vary across species. In Aspergillus fumigatus, the etiological agent of invasive aspergillosis, septins participate in a variety of processes, including conidiation, septation, and responses to cell wall stress. Previous studies determined that the ΔaspB septin deletion strain had a greater sensitivity to anti-cell wall drugs, especially the echinocandins, yet mechanisms behind this augmented sensitivity are unknown. We performed cell viability s

Hypothermia and nutrient deprivation alter viability of human adipose-derived mesenchymal stem cells.

PURPOSE: Adipose-derived mesenchymal stem cells (MSCs) are attractive biological agents in regenerative medicine. To optimize cell therapies, it is necessary to determine the most effective delivery method for MSCs. Therefore, we evaluated the biological properties of MSCs after exposure to various temperatures to define optimal storage conditions prior to therapeutic delivery of MSCs. DESIGN: Prospective observational study. METHODS AND MATERIALS: Adherent and non-adherent MSCs were incubated at multiple temperatures (i.e., 4, 23 and 37 °C) in Lactated Ringers (LR) solution lacking essentia

Ultraviolet-C irradiation for inactivation of viruses in foetal bovine serum.

Foetal Bovine Serum (FBS) and porcine trypsin are one of the essential raw materials used in the manufacturing of cell culture based viral vaccines. Being from animal origin, these raw materials can potentially contaminate the final product by known or unknown adventitious agents. The issue is more serious in case of live attenuated viral vaccines, where there is no inactivation step which can take care of such adventitious agents. It is essential to design production processes which can offer maximum viral clearance potential for animal origin products. Ultraviolet-C irradiation is known to i

Foot and Ankle Care in the News: Media Representation Across Provider Types.

BackgroundOnline news media increasingly shapes patient understanding of musculoskeletal disease and influences care-seeking behavior. Foot and ankle (F&A) conditions are managed by overlapping specialties, yet their representation in public-facing media coverage is undefined.MethodsA cross-sectional analysis of patient education Google News articles was conducted for 4 foot and ankle pathologies: bunions, flatfoot deformity, plantar fasciitis, and Achilles tendonitis. Articles published January 1, 2025, to January 1, 2026, were retrieved via standardized incognito searches conducted on Februa

Primary prevention of malignant melanoma in the Stockholm Cancer Prevention Programme.

Malignant melanoma is the most rapidly increasing tumour in Sweden. Sunburns in childhood and adolescence are considered a major risk factor. The Stockholm Cancer Prevention Programme addresses strategies to establish sun awareness in the population of Stockholm county by using existing networks of standardized child health and preschool services, educational systems including schools, colleges of nursing sciences and preschool teaching (integration of sun awareness in curricula, and in a new syllabus for environmental theory), the Federation of Swedish Pharmacies, and media. Health education

Screen time and attention-deficit/hyperactivity disorder in children: a systematic review and meta-analysis.

BACKGROUND: Children's exposure to electronic screens has risen sharply. This study quantitatively evaluated the association between excessive screen time and childhood attention-deficit/hyperactivity disorder (ADHD) risk through a systematic review and meta-analysis, exploring the moderating roles of age and media type. METHODS: Following PRISMA guidelines, we systematically searched observational studies assessing children's screen time and ADHD, and finally included 10 observational studies with overall low-to-moderate risk of bias. Risk of bias was evaluated using the ROBINS-I tool. Conti

[Significance of biological indicators of mercury exposure].

BACKGROUND: It was considered appropriate to update of the significance and use of the different mercury exposure indicators. OBJECTIVE: The aim of the this paper was to correctly select biological media and sampling time and to understand the toxic kinetics of mercury for assessment of accurate biological monitoring. RESULTS: It was confirmed that mercury in blood (B-Hg) is a good indicator of recent exposure, while urinary mercury (U-Hg) indicates current exposure when mercury reaches the renal steady state. B-Hg values are greatly influenced by fish consumption, while the variables influe

Beyond Numbers: Opportunities and Challenges Using Qualitative Methods in Social Media Studies of PrEP Discourse.

Using pre-exposure prophylaxis (PrEP) discourse as a case study, we examine qualitative and multi-method approaches to analyzing health communication on social media platforms. These platforms have become crucial spaces for health promotion and community discourse, particularly on HIV prevention. Our review of 23 PrEP-focused studies that used social media data documents the different strengths of both methodologies. Qualitative analyses were strong at capturing how platform architecture shaped discourse quality: Reddit's forum structure enabled deeper narratives while X's (formerly Twitter) c

Trichloroethylene metabolism in vitro: an EPR/SPIN trapping study.

Trichloroethylene (TCE) was hypothesized to produce free radicals which could be detected using electron paramagnetic resonance spectroscopy with the spin trap, PBN (alpha-phenyl tert-butyl nitrone). The free radicals detected following incubation of precision cut liver slices in media containing 10 mM PBN had hyperfine coupling constants aN = 1.61 mT and aH = 0.325 mT. There was a linear increase in free radicals detected in the bathing media when the headspace TCE concentration was increased from 2500-10000 p.p.m. The levels of conjugated dienes measured in the slices incubated in PBN supple

Toxicity assessment of exposure to four short- and ultra-short PFAS using Daphnia magna and Hydra vulgaris as models.

Short- and ultra-short per- and polyfluoroalkyl substances (PFAS) such as perfluorobutanoic acid (PFBA, 4C), perfluorobutane sulfonic acid (PFBS, 4C), trifluoroacetic acid (TFA, 2C) and trifluoromethane sulfonic acid (TFMS, 1C) were detected in various environmental matrices, but studies addressing the effects attributed to exposure are still scarce. This study aimed to (1) investigate acute toxicity of these emerging PFAS using Daphnia magna (immobility, mortality, reproduction, and body size) and Hydra vulgaris (morphological changes and reproduction) and (2) assess the sub-chronic/chronic t

Like-minded sources on Facebook are prevalent but not polarizing.

Many critics raise concerns about the prevalence of 'echo chambers' on social media and their potential role in increasing political polarization. However, the lack of available data and the challenges of conducting large-scale field experiments have made it difficult to assess the scope of the problem1,2. Here we present data from 2020 for the entire population of active adult Facebook users in the USA showing that content from 'like-minded' sources constitutes the majority of what people see on the platform, although political information and news represent only a small fraction of these exp

Risk of anaphylaxis in a hospital population in relation to the use of various drugs: an international study.

PURPOSE: To evaluate the risk of anaphylaxis following exposure to medications given during hospitalization. METHODS: Cases with anaphylaxis and controls, matched according to length of hospital stay, were enrolled from hospitals in Hungary, Spain, India and Sweden. Exposures were recorded from the hospital record. The incidence of anaphylaxis was calculated among those exposed to various drugs, with denominators estimated from exposure rates in the controls and number of hospitalizations. RESULTS: Among 184 cases and 1003 controls, the incidence of anaphylaxis was in the range of 5-15 cases

"It's Like Plan B but for HIV!" Design and Evaluation of a Media Campaign to Drive Demand for PEP.

Post-exposure Prophylaxis (PEP) is an effective yet underutilized HIV prevention tool. PEPTALK developed and evaluated a media campaign to drive demand for PEP among men who have sex with men (MSM) and transgender women (TW) living in high HIV prevalence areas in New York City. Formative qualitative research (38 in-depth interviews and five focus groups [N = 48]) with Black or African-American MSM or TW who reported condomless sex with a HIV-positive/unknown status man was conducted to inform campaign design. We assessed the impact of the campaign, 15 bus shelter ads and low or no-cost social

Use of Intravenous Iodinated Contrast Media in Patients With Kidney Disease: Consensus Statements from the American College of Radiology and the National Kidney Foundation.

Intravenous iodinated contrast media are commonly used with CT to evaluate disease and to determine treatment response. The risk of acute kidney injury (AKI) developing in patients with reduced kidney function following exposure to intravenous iodinated contrast media has been overstated. This is due primarily to historic lack of control groups sufficient to separate contrast-induced AKI (CI-AKI; ie, AKI caused by contrast media administration) from contrast-associated AKI (CA-AKI; ie, AKI coincident to contrast media administration). Although the true risk of CI-AKI remains uncertain for pati

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… This risk is much higher than the risk of CI-AKI because it includes any AKI coincident to contrast media administration, regardless of contrast media exposure. … N -acetylcysteine was not shown to be effective versus placebo in a recent randomized trial of intra-arterial iodinated contrast media administration 40 and is not recommended for intravenous contrast media exposure prophylaxis. …

A Trans-Agency Workshop on the Pathophysiology of Radiation-Induced Lung Injury.

BACKGROUND: The rapid growth of social media has profoundly transformed communication, community building, and information sharing worldwide. In Afghanistan, the proliferation of social media platforms has significantly impacted the social, cultural, and political landscape, particularly among the youth. OBJECTIVE: This multi-disciplinary study aims to explore the diverse effects of social media on Afghan youth, focusing on usage patterns, mental health implications, entertainment-driven time allocation, financial expenditures, exposure to explicit content, and academic performance. METHODS:

The Mediating Role of Social Sensitivity in the Relationship Between Mindfulness and Secondary Traumatic Stress Among Social Media Users.

Exposure to traumatic events such as disasters, violence, and wars through social media has been associated with psychological distress and secondary traumatic stress (STS). However, limited evidence exists regarding how mindfulness and social sensitivity are associated with this digital form of trauma. This study examined the relationships among mindfulness, social sensitivity, and STS among social media users and tested the mediating role of social sensitivity. A descriptive, cross-sectional study was conducted in April 2025 with 433 social media users in Türkiye. Data were collected using t