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Abstracts of the Cell Therapy Transplant Canada 2022 Annual Conference.

On behalf of Cell Therapy Transplant Canada (CTTC), we are pleased to present the Abstracts of the CTTC 2022 Annual Conference. The conference was held in-person 15-18 June 2022, in Niagara Falls, Ontario. Poster authors presented their work during a lively and engaging welcome reception on Thursday, 16 June, and oral abstract authors were featured during the oral abstract session in the afternoon on Friday, 17 June 2022. Thirty-three (33) abstracts were selected for presentation as posters and six (6) as oral presentations. The top abstracts in each of four (4) categories, (1) Basic/Translati

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Targeting the proteasome in cancer therapy: development and future opportunities in natural products.

BACKGROUND: The ubiquitin-proteasome pathway is a critical therapeutic target in malignancies, particularly multiple myeloma. The development of proteasome inhibitors (PIs) has marked a milestone in multiple myeloma therapy and now constitutes the backbone of frontline treatment regimens. However, primary and acquired resistance remain a major challenge, underscoring the need to identify new PIs as well as agents that can resensitize resistant cells. METHOD: This review provides an overview of the current clinical applications of PIs and offers a comprehensive summary of natural products that

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… Like other PIs, epoxomicin also displayed anti-parasitic activity, inhibiting Plasmodium ( Czesny et al., 2009 ) and Babesia ( AbouLaila et al., 2010 ) growth at nanomolar concentrations. …

Epidemiology of infections in cancer patients.

Although major advances in the care of cancer patients over the past several decades have resulted in improved survival, infectious complications remain a significant cause of morbidity and mortality. To successfully identify, treat, and prevent infections, a comprehensive understanding of risk factors that predispose to infection and of commonly encountered pathogens is necessary. In addition, clinicians must keep abreast of the changing epidemiology of infections in this population. As therapeutic modalities continue to evolve, as established pathogens become increasingly drug resistant, and

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… Babesia microti, a tick-borne protozoan parasite, has been transmitted through transfusion along coastal regions of the Northeastern United States. It can cause a life-threatening infection in immunocompromised, especially asplenic, patients [ 171 , 174 ]. …

References

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… Transmission of Babesia microti in Minnesota through four blood donations from the same donor over a 6-month period. Transfusion. 2002;42:1154–1158. doi: 10.1046/j.1537-2995.2002.00189.x. 110. Kain KC, Jassoum SB, Fong IW, Hannach B. …

Сердечно-сосудистые заболевания

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Integumentary System

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Biology and Diseases of Dogs

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Emergency Care

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… Canine donors also should be screened initially for Lyme disease, Babesia, Rocky Mountain spotted fever (Rickettsia rickettsii), Ehrlichia, and Brucella. The prevalence of Babesia species in the racing Greyhound industry in Florida, Arizona, and Colorado is high (estimated to be 30% to 50%). …

C

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33rd Европейский конгресс патологии - резюме.

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Research Communications of the 26th ECVIM‐CA Congress

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… We performed PCRs ( Ehrlichia canis , Anaplasma platys / phagocytophilum, Babesia / Theileria spp, Hepatozoon sp., Mycoplasma haemocanis (MH)/ Candidatus M.haematoparvum, Leishmania spp) and serological tests (SNAP ® 4Dx, SNAP ® Leish). …

Abstracts from the 37th Annual Meeting of the Society of General Internal Medicine, 2014, San Diego, CA, USA.

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Резюме докладов 2017 Ежегодное совещание Общества общей внутренней медицины.

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