Результаты поиска

Infections and autoimmune diseases.

The high percentage of disease-discordant pairs of monozygotic twins demonstrates the central role of environmental factors in the etiology … he induction of a Guillain-Barré syndrome in rabbits after immunization with a peptide derived from Campylobacter jejuni is explained by mimicry between C. jejuni antigens and peripheral nerve axonal antigens. Other models involve chemical modification of autoantigens, as in the case of iodine-induced autoimmune thyroiditis. These mechanisms have so far only li …

Estimated global and regional causes of deaths from diarrhoea in children younger than 5 years during 2000-21: a systematic review and Bayesian multinomial analysis.

BACKGROUND: Information on the causes of deaths from diarrhoea in children younger than 5 years is needed to design improved preventive and … , "diarrhea", "diarrhoea", "dysentery", "rotavirus", "Escherichia coli", "salmonella", "shigella", "campylobacter", "Vibrio cholerae", "cryptosporidium", "norovirus", "astrovirus", "sapovirus", and "adenovirus". To be included, studies had to have a patient population of children younger than 5 years who were hospitalised for diarrhoea (at least 90% of study pa …

Microbial alterations in supragingival dental plaque in response to a triclosan-containing dentifrice.

A total of 325 subjects were entered into a double-blind, stratified 2-treatment clinical study that examined the effects of a dentifrice containing 0.3% triclosan, 2% Gantrez copolymer and 0.243% sodium fluoride on supragingival dental plaque and gingivitis. A subset of 159 subjects including 72 men and 87 women participated in the microbiological component of this study, which was designed to detect shifts in supragingival bacterial species in response to triclosan. Subjects were divided into two groups: one performed normal oral hygiene with the triclosan/copolymer dentifrice and a control

Climate changes, environment and infection: facts, scenarios and growing awareness from the public health community within Europe.

Climate change is a current global concern and, despite continuing controversy about the extent and importance of causes and of its effects, … In addition, health effects of flooding, have been related to an excess cases of leptospirosis and campylobacter enteritis. Such examples have been demonstrated reported after flooding in the Czech Republic. Similarly, an increase of cryptosporidiosis in the United Kingdom has been related to flooding. Changing vector distributions associated with tickborne en …

Combined Immune Defect in B-Cell Lymphoproliferative Disorders Is Associated with Severe Infection and Cancer Progression.

B cell chronic lymphoproliferative diseases (B-CLPD) are associated with secondary antibody deficiency and other innate and adaptive immune defects, whose impact on infectious risk has not been systematically addressed. We performed an immunological analysis of a cohort of 83 B-CLPD patients with recurrent and/or severe infections to ascertain the clinical relevance of the immune deficiency expression. B-cell defects were present in all patients. Patients with combined immune defect had a 3.69-fold higher risk for severe infection (p = 0.001) than those with predominantly antibody defect. Inte

Совпадение в полном тексте источника
… Specific causal infection by Campylobacter jejuni was documented in one patient. … In our cohort, seven patients with long-term malabsorptive symptoms gave rise to suspicion of a concomitant undiagnosed disease, such as sprue-like illness, Campylobacter jejuni infection. …

Challenges in the Diagnosis and Management of the Miller Fisher Variant of Guillain-Barré Syndrome: A Case Report.

Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS), characterized by the triad of ophthalmoplegia, ataxia, and areflexia, often following a bacterial or viral illness. This case report presents a 58-year-old Hispanic female patient with a preceding streptococcal pharyngitis who developed symptoms of bilateral facial nerve palsy and lower limb ataxia. Cerebrospinal fluid (CSF) analysis revealed albuminocytologic dissociation and, combined with her presentation of ophthalmoplegia, ataxia, and areflexia, supported the diagnosis of MFS. Magnetic resonance imaging (MRI)

Совпадение в полном тексте источника
… The most common infectious triggers are Campylobacter jejuni and Haemophilus influenzae , while less common causes include cytomegalovirus, Epstein-Barr virus, and human immunodeficiency virus (HIV) [ 2 , 3 ]. … The most common bacterial trigger has been Campylobacter jejuni , and the most common viral triggers have been HIV, Epstein-Barr virus, and Zika virus [ 2 ]. In a study, sore throat was statistically more frequent in MFS (18/24 cases, 75%) than in GBS (29/58, 50%). …

Surveillance of Waterborne Disease Outbreaks Associated with Drinking Water - United States, 2015-2020.

PROBLEM/CONDITION: Public health agencies in U.S. states, territories, and freely associated states investigate and voluntarily report water … izations. No deaths were reported. Among these illnesses, three pathogens (norovirus, Shigella, and Campylobacter) or multiple etiologies including these pathogens resulted in 1,225 (94%) cases. The drinking water source was identified most often (n = 34; 7%) as the contributing factor in enteric disease outbreaks. When water source (e.g., groundwater) was know …

Guillain-Barré syndrome in patients with multiple myeloma: three cases report and literature review.

BackgroundMultiple myeloma (MM) with Guillain-Barré syndrome (GBS) is relatively rare, and the specific mechanism is still unclear. The previous infection, surgery, and medication use may have contributed to the occurrence of GBS. The use of bortezomib in patients with MM can easily lead to peripheral neuropathy, which is similar to the symptoms of GBS, making it challenging to diagnose GBS.Cases presentationThree patients with IgA type MM experienced lower limb weakness during treatment. Combined with lumbar puncture, nerve conduction studies, and other tests, the diagnosis was confirmed as G

Совпадение в полном тексте источника
… The reported pathogens of GBS precursor infection include Campylobacter jejuni, Mycoplasma pneumoniae, Haemophilus influenzae, Japanese encephalitis virus, Epstein-Barr virus, herpes simplex virus, cytomegalovirus, and Zika virus [ 13 – 15 ]. … Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies [J]. Brain, 1995;118( Pt 3):597–605. Associated Data Data Availability Statement No datasets were generated or analysed during the current study. …

Human microbiomes in cancer development and therapy.

Colonies formed by bacteria, archaea, fungi, and viral groups and their genomes, metabolites, and expressed proteins constitute complex human microbiomes. An increasing evidences showed that carcinogenesis and disease progression were link to microbiomes. Different organ sources, their microbial species, and their metabolites are different; the mechanisms of carcinogenic or procancerous are also different. Here, we summarize how microbiomes contribute to carcinogenesis and disease progression in cancers of the skin, mouth, esophagus, lung, gastrointestinal, genital, blood, and lymph malignancy

Совпадение в полном тексте источника
… A high abundance of Fusobacterium, Actinomyces, Facracter , and Campylobacter was found in the urine of patients with bladder cancer, while Streptococcus and Corynebacterium were higher in the urine of healthy people. … Detection of IL‐18 and IL‐1β protein and mRNA in human oral epithelial cells induced by Campylobacter concisus strains. Biochem Biophys Res Commun. 2019;518(1):44‐49. 35. Nagata N, Takeuchi T, Masuoka H, et al. …

Risk of Hematologic Malignancies in Patients with Inflammatory Bowel Disease: A Meta-Analysis of Cohort Studies.

Background/aimsInflammatory bowel disease (IBD) may contribute to the development of hematologic malignancies. In this study, the potential relationship between IBD and hematologic malignancies was investigated.MethodsWe searched the PubMed, Web of Science, Embase, and Cochrane Library databases for all cohort studies comparing the incidence of hematologic malignancies in non-IBD populations with that in IBD patients, and we extracted relevant data from January 2000 to June 2023 for meta-analysis.ResultsTwenty cohort studies involving 756,377 participants were included in this study. The resul

Совпадение в полном тексте источника
… proven that Helicobacter pylori is a risk factor in more than 90% of cases of gastric mucosa-associated lymphoid tissue lymphoma, 42 and the same pathological pattern exists in mice with chronic H. pylori infection, especially Felis H. pylori . 43 In addition, studies have shown that bacteria such as Campylobacter … jejuni , Chlamydia psittaci , and Borrelia berenii are also involved in the development of human lymphoma. 33 It has been found that a series of bacteria causing intestinal infections, such as Campylobacter , 44 will increase the risk of IBD, and bacterial infections recur throughout the course of the …

Pneumonia in the Cancer Patient

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Influenza B Parainfluenza type-3 Respiratory syncytial virus Adenovirus Varicella-zoster virus HHV-6 SARS-associated coronavirus Paramyxovirus Hantavirus Humoral immune S. pneumoniae VZV Dysfunction Haemophilus influenzae Echovirus Splenctomy Neisseria meningitidis Enterovirus Capnocytophaga canimorsus Campylobacter … Respiratory syncytial virus Adenovirus Varicella-zoster virus HHV-6 SARS-associated coronavirus Paramyxovirus Hantavirus Humoral immune | S. pneumoniae | | | VZV Dysfunction | Haemophilus influenzae | | | Echovirus Splenctomy | Neisseria meningitidis | | | Enterovirus Capnocytophaga canimorsus | | | Campylobacter …

Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial.

BACKGROUND: Hyperbaric oxygen has been used as a therapy for patients experiencing chronic intestinal syndromes after pelvic radiotherapy fo … ry [grade 3]; recurrence of vomiting and dehydration [grade 3]; diarrhoea and fever associated with Campylobacter infection [grade 3]; recurrence of abdominal pain, bloating, diarrhoea, and urinary tract infection [grade 3]; aneurysm [grade 4]), none of which were deemed treatment-related. INTERPRETATION: We found no evidence that patients with radiation-induc …

Conference Proceedings - 6th International Conference on Molecular Diagnostics and Biomarker Discovery (MDBD 2022): Building Resilience in Biomedical Research : Penang, Malaysia. 11-13 October 2022.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Роль микробиомы в множестве миелом: новые знания и терапевтические возможности.

Множественная миелома — гематологический рак, описываемый распространением плазменных клеток в костном мозге, что вызывает иммунную дисфункцию и другие аномалии. Микробиом кишечника, микробное сообщество в желудочно-кишечном тракте, было обнаружено, что он модифицирует системный иммунитет, воспаление и метаболизм. Хотя взаимосвязь между кишечным микробиомом и множеством миелома была обнаружена в недавних исследованиях, существует пробел в знаниях, связывающий воздействие микробиома на патогенез и лечение множественной миеломы. Несбалансированность в кишечном микробиоме, дисбиозе, может влиять

Совпадение в полном тексте источника
… Apart from immune dysregulation and alterations in signaling pathways, Escherichia coli and Campylobacter jejuni have proven to promote carcinogenesis through the production of directly genotoxic metabolites colibactin and cytolethal distending toxin, respectively. … A study conducted by He et al., for example, highlighted the role of Campylobacter jejuni in the formation of colorectal cancer by altering the microbial composition through the DNAse activity of the genotoxin cytolethal distending toxin [ 52 ]. …

Клиническое представление лептоспироза: ретроспективное исследование 34 Пациенты поступили в одно учебное заведение во Франции.

Лептоспироз имеет весьма изменчивое клиническое представление, которое может быть связано с различными заражающими сероварами, факторами хост-компьютеров или их комбинацией. Это исследование проводилось ретроспективно 34 Число пациентов с серологическим подтвержденным лептоспирозом, принятых в течение отчетного периода 1992-2002. Наиболее частыми симптомами при поступлении в школу были лихорадка (см.100%), головная боль75%), миальгии55%), артхальгии45%) и рвотой (т.е.39%). Применяемые лабораторные исследования включали в себя лимфопенцию (см.85%), тромбоцитопенсия75%), повышенные ферменты пече

Genome-wide association study of periodontal pathogen colonization.

Pathological shifts of the human microbiome are characteristic of many diseases, including chronic periodontitis. To date, there is limited evidence on host genetic risk loci associated with periodontal pathogen colonization. We conducted a genome-wide association (GWA) study among 1,020 white participants of the Atherosclerosis Risk in Communities Study, whose periodontal diagnosis ranged from healthy to severe chronic periodontitis, and for whom "checkerboard" DNA-DNA hybridization quantification of 8 periodontal pathogens was performed. We examined 3 traits: "high red" and "high orange" bac

Dengue-Related Hemophagocytic Lymphohistiocytosis in an Adult: A Case Report and Brief Update.

Dengue virus is an arbovirus transmitted through the bite of infected Aedes mosquitoes. Many unusual clinical features are being reported in dengue. Dengue complicated with hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal condition. Here, we report an 18-year-old otherwise healthy female with dengue fever complicated with HLH. The diagnosis was made by fulfilling the clinical and laboratory criteria of HLH. She was managed successfully with a methylprednisolone pulse regimen. Our case highlights the importance of early recognition of complications and prompt treatment f

Совпадение в полном тексте источника
… (HIV), human T-lymphotropic virus (HTLV), adenovirus, HAV, HBV, HCV, measles, mumps, rubella, dengue, hantavirus, parvovirus B19, parechovirus, enterovirus, H1N1 influenza virus, and recently severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) Bacterial infections | Staphylococcus aureus, Campylobacter …

Стрессивая симметрия: паралич двустороннего Белла, потенциально вызванный экстремальным стрессом.

Лица с нервыми (FNP) идиопатического происхождения обычно называются параличом Белла. Двусторонний ФНП представляет собой исключительно редкую подгруппу всех дел, связанных с параличом Белла. Она может проявляться либо синхронно, либо последовательно, с одной стороны, с другой стороны, с последующим участием противоположной стороны в течение первых 30 дней с момента возникновения симптома. Обычные этиологии ФНП охватывают такие инфекции, как инфекционный мононуклеоз, грипп, болезнь лайма и менингит. Неинфекционные причины включают в себя новообразования, множественный склероз и синдром Гильен-

Совпадение в полном тексте источника
… A rare, potentially life-threatening disease to rule out is GBS, an acute post-inflammatory polyneuropathy often preceded by illness commonly caused by Campylobacter jejuni , Epstein-Barr virus, or even influenza. …

Accidental Ixazomib Overdose in a Patient With Multiple Myeloma.

Multiple myeloma is the second most common hematological malignancy. Ixazomib is the first oral proteasome inhibitor approved in the United States for the management of multiple myeloma who have received at least one prior treatment. The availability of oral chemotherapeutic agents for the management of multiple myeloma has made it easier for patients who do not have to come to the hospital for chemotherapy infusions. However, many barriers are associated with oral chemotherapy, and one of them is a misinterpretation of instruction which can have deleterious effects. In this case report, we pr

Совпадение в полном тексте источника
… Test performed | Polymerase chain reaction result Campylobacter spp | Not detected Clostridium difficile toxin A/B genes | Not detected Plesiomonas shigelloides | Not detected Salmonella spp | Not detected Vibrio spp | Not detected Vibrio cholerae | Not detected Yersinia enterocolotica | Not detected …

Radiotherapy in COVID-19 patient affected by multiple myeloma: a case report.

In COVID-19 pandemic, cancer patients may be vulnerable for their immunological status and need of immunosuppressive anti-neoplastic treatments. Choosing the best treatment option in COVID-19 positive cancer patients is still a challenging issue. We report the case of a 62-year-old woman diagnosed with multiple myeloma and affected by COVID-19. After the diagnosis of multiple myeloma in January 2019, the patient underwent first line therapy followed by bone marrow autologous stem cell transplantation, achieving a complete response in September 2019. In March 2020, the patient showed intrathora

Совпадение в полном тексте источника
… She was tested for H1N1 and other respiratory flu viruses, chlamydia, mycoplasma, legionella, cytomegalovirus, campylobacter, aspergillus. While waiting for the results of blood and urine cultural tests (which were all negative), she was admitted to the Internal Medicine inward. …