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Computer-assisted Diagnostic Checklist in Clinical Neurology.

Considering computers are more efficient at processing large amounts of information than the human brain, speaks to the need to explore more intelligent computer-assisted diagnostic approaches. Two diagnostic checklist programs, one for single key term entry (NeurologyINDEX), and another, with more advanced algorithms to process multiple key terms and perform additional functions (NeurologicDx) are discussed. Both programs are internet based, access the same database, and are designed to generate diagnostic checklists and disease profiles accessible with hand-held or other computer device. The…

The Tripartite Influence Model: New conceptualizations and measurement strategies based on an evolving social media onslaught.

The metastasizing of social media from a nodule of internet foci - Facebook, Instagram, TikTok, YouTube - to far flung lymph nodes of AI, ChatGPT, Grok, and beyond, aided by blood flow provided by AI silicon tech-savants, often without a moral compass, can easily overwhelm the need to return to our rock foundations of research, and what changes we must make to keep us in step with the often capricious improvisations of the latest social media dance craze. In this commentary, I suggest how an evolution of measurement and theory, can provide a framework for future work in the area of social medi…

[Ophthalmic agents during pregnancy].

The use of ophthalmic agents during pregnancy and breastfeeding always represents an off-label use. Therefore, the use of drugs must be particularly carefully assessed with respect to the risk-benefit assessment. In this overview the literature databank of the PubMed library, pharmaceutical lists (Red List, Swiss pharmaceutical compendium), guidelines of the specialist societies the German Society of Ophthalmology (DOG), the Swiss Society of Ophthalmology (SOG), the European Glaucoma Society (EGS), the American Academy of Ophthalmology (AAO) and internet portals (embryotox, reprotox) were insp…

Evolution and trends of hikikomori: a bibliometrics analysis.

Hikikomori is the Japanese term for the phenomenon of young adults isolating themselves from society and becoming reclusive. This study aims to examine the evolution and distribution of hikikomori, as well as identify the major players and institutions involved in hikikomori research. The searches, which were conducted in Scopus database identified 286 academic research works pertaining to hikikomori research. The findings indicate that hikikomori has attracted the attention of academic researchers in both the East and the West, with a consistent increase in research output since the Internet …

Acceptance of a Future Gonorrhea Vaccine in a Post-Coronavirus Disease 2019 World: Impact of Type of Recommendation and Changing Levels of Trust in Health Institutions and Authorities.

Widespread uptake of a future gonorrhea vaccine could decrease the burden of disease and limit the spread of antibiotic resistance. However, gonorrhea vaccination will occur in the backdrop of the roll-out of the coronavirus disease 2019 (COVID-19) vaccine, which could have influenced parental perceptions about other, non-COVID-19 vaccines. In an internet-based cross-sectional survey, 74% of parents would get a gonorrhea vaccine for their child, and this was higher among those whose trust in pharmaceutical companies increased since the start of the COVID-19 pandemic. About 60% of adults aged 1…

Cerebrospinal fluid analysis and the determination of oligoclonal bands.

This document presents the guidelines for the cerebrospinal fluid (CSF) analysis and the determination of oligoclonal bands (OCBs) as pivotal tests in neuroinflammatory pathologies of the central nervous system. The guidelines have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on the pathologies in which the CSF analysis is indicated, and, particularly, on those characterized by the presence of OCBs in th…

Comprehensive Review and Comparison of the Disinfection Techniques Currently Available in the Literature.

The goal of disinfection in the dental office is to prevent the spread of infection from one patient to another and maintain the safety of t … on method, and sterilization of dental impression from 1980 to 2016 in Medline, Google Scholar, the internet, and textbooks. This article critically analyzes the various published methods of dental impression disinfection in dentistry.

Definition of Substance and Non-substance Addiction.

Substance addiction (or drug addiction) is a neuropsychiatric disorder characterized by a recurring desire to continue taking the drug despite harmful consequences. Non-substance addiction (or behavioral addiction) covers pathological gambling, food addiction, internet addiction, and mobile phone addiction. Their definition is similar to drug addiction but they differ from each other in specific domains. This review aims to provide a brief overview of past and current definitions of substance and non-substance addiction, and also touches on the topic of diagnosing drug addiction and non-drug a…

Behavioral addictions in addiction medicine: from mechanisms to practical considerations.

Recent progress has been made in our understanding of nonsubstance or "behavioral" addictions, although these conditions and their most appropriate classification remain debated and the knowledge basis for understanding the pathophysiology of and treatments for these conditions includes important gaps. Recent developments include the classification of gambling disorder as a "Substance-Related and Addictive Disorder" in the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and proposed diagnostic criteria for Internet Gaming Disorder in Section 3 of DSM-5. This ch…

Инфодемиология и инфовелленс множественных склерозов в Италии

Множественный склероз (MS) является хроническим изнурительным заболеванием вероятной аутоиммунной провокационной природы, аэтология которого не в полной мере понята, несмотря на многочисленные усилия и исследования. В этой рукописи мы пересматриваем концепцию < < мультипликаторного склероза 2.0 > > , т.е. использование Интернета пациентами, страдающими MS, для поиска медицинских и связанных с болезнями материалов для целей самообслуживания и саморегулирования, и внедряем основанный на Google Trends подход к мониторингу связанных с MS запросов и поисков в Google, который называется

Совпадение в аннотации оригинала
Multiple Sclerosis (MS) is a chronic debilitating disease of probable autoimmune inflammatory nature, whose aetiology is not fully understood, despite the many efforts and investigations. In this manuscript, we review the concept of “Multiple Sclerosis 2.0”, that is to say the Internet usage by MS patients, for seeking health and disease-related material for…

Database of the clinical phenotypes, genotypes and mutant arylsulfatase B structures in mucopolysaccharidosis type VI.

Mucopolysaccharidosis type VI (MPS VI) is a genetic disorder caused by a deficiency of arylsulfatase B (ARSB). In our previous study, we investigated the structural changes in ARSB caused by amino acid substitutions associated with MPS VI, and revealed that such structural changes in ARSB were correlated with the clinical phenotypes. To the best of our knowledge, there is no database containing the structures of mutant ARSBs. Here, we built a database of clinical phenotypes, genotypes and structures of mutant ARSBs (http://mps6-database.org). This database can be accessed via the Internet, and…

Usage of support services in primary lateral sclerosis.

Patients with amyotrophic lateral sclerosis (ALS) rely on a variety of support services during the course of their illness. Patients with pr … lp for activities requiring mobility. As in other chronic diseases, there was a striking use of the internet to gather information and for patient support groups.

Guidelines for the prevention, diagnosis and treatment of compensatory hyperhidrosis.

With the objective of establishing guidelines for the prevention, diagnosis and treatment of compensatory hyperhidrosis, consensus meetings … revised and subsequently approved by all of the participants. The consensus text was posted on the Internet, becoming the object of further corrections and revisions prior to taking on its present form.

Chemotherapy and cutaneous toxicities: implications for oncology nurses.

OBJECTIVE: To review common cutaneous effects and dermatologic or cutaneous toxicities related to the administration of chemotherapy. These range from mostly cosmetic, such as hyperpigmentation or alopecia, to dose-limiting toxicities such as palmar-plantar erythrodysesthesia or hand-foot syndrome. DATA SOURCES: Current research, published literature, and internet resources. CONCLUSION: Assessment and grading of associated toxicities of therapy is an integral part of caring for this patient population. Early intervention may reduce toxicities associated with therapies for this patient popula…

Renal cystic disease: new insights for the clinician.

This article cannot comprehensively cover the enormous strides made in defining the molecular and cellular basis of renal cystic diseases over the last decade. Therefore, it provides a brief overview and categorization of inherited, developmental, and acquired renal cystic diseases, providing a relevant, up-to-date bibliography as well as a useful list of informative Internet Web sites. Its major focus is the translational biology of polycystic kidney disease. It demonstrates how emerging molecular and cellular knowledge of the pathophysiology of particular diseases such as autosomal dominant …

A Dynamic Blood Information Management System Based on RFID.

As a patient and recipient of a blood transfusion, it is important for him or her to receive the safest blood possible. Information about th … so that real-time data can be transmitted between the bloodmobile and blood center through wireless Internet.

Could it happen here? Vaccine risk controversies and the specter of derailment.

Controversy over vaccine safety has achieved high visibility over the past decade. At the same time, however, levels of coverage for routinely recommended childhood vaccines in the United States are at their highest ever. We examine this apparent paradox. We consider the ways in which concerns over vaccine safety have emerged and diffused through the popular media, legislative hearings, and Internet-based activism. As a case study, we review the controversy over the alleged connection between autism and the measles-mumps-rubella (MMR) vaccine and consider why it had a dramatic effect on the va…

Fetal surgery for spina bifida aperta: to be or not to be?

Fetal SBA (spina bifida aperta) has been operated upon in more than 213 cases in the USA in the last 8 years. Indications and results still remain controversial. Our group reproduced successfully Meuli's model in sheep and reviewed the literature on SBA and the Internet updated sites on the theme. Then we reviewed the follow-up of all cases operated upon postnatally in 20 years at a Neurosurgery Department in Rome. We published all the data regarding the three above-mentioned steps. This paper contains reflections on the three, and our opinion on the correct approach to prenatally diagnosed SB…

[Monitoring human African trypanosomiasis in Central Africa in 2001 and cartography: results and perspectives].

Cases of human African trypanosomiasis are distributed in changing geographical "outbreak areas" that can be visualized over time and space. … s preliminary results. Also presented in this article is the Trypinfo site being development on the internet to increase the surveillance response-time and improve the feedback system.

Genetic renal diseases in children.

In this review, a survey is given of genetic renal diseases in which recent progress has been made regarding the study of their molecular ge … isease, has recently provided an international database called kidbase, which is accessible via the Internet.