Результаты поиска

[An immunosuppressed woman in her seventies with night sweats and weight loss].

BACKGROUND: Candidatus Neoehrlichia mikurensis is an emerging tick-borne pathogen with widespread distribution in Ixodes ricinus ticks in Eu … s resolved promptly after initiation of oral doxycycline treatment. INTERPRETATION: Infection with anaplasmataceae such as Candidatus Neoehrlichia mikurensis can present with non-specific constitutive symptoms. In this case, persistent night sweats and moderate weight loss were the only manifestations over an eight-month period. Diagnosis is readily established …

Diversity of Ehrlichia spp., Anaplasma spp. and Neorickettsia spp. in vampire bats.

Although bats (Mammalia: Chiroptera) act as natural reservoirs for many zoonotic pathogens around the world, few studies have investigated the occurrence of Anaplasmataceae agents in bats, especially vampire bats. The family Anaplasmataceae (order Rickettsiales) encompasses obligate intracellular bacteria of the genera Anaplasma, Ehrlichia, Neorickettsia, Neoehrlichia, Wolbachia, and Allocryptoplasma. The present study aimed to investigate, using molecular techniques, the presence of species of Anaplasma, Ehrlichia, and Neorickettsia in vampire bats sampled in northern Brazil. Between 2017 and…

Присутствие Rickettsia eschlimannii, Candidatus Rickettsia barbariae и Coxiella signetii в клещах от скота в северо-западном Алжире.

Скотоводство и его эктопарациты участвуют в эпидемиологии нескольких зоонотических заболеваний. Исследования, касающиеся молекулярного обнаружения инфекционных агентов в клещах из северо-западного Алжира, недостаточны. Таким образом, было расследовано присутствие группы рикеттсии, микроорганизмов Anaplasmaciae и печени Coxiella signetii в клещах, собранных у румын в провинциях Сиди-Бель-Аббес и Сайда. Рикетсия Эшлиманнаи была обнаружена в одном экскавационном бассейне < < Хьяломма > > и одном пуле < < Х. саркатум > > . Более того, "Candidatus Rickettsia barbariae" был н

Совпадение в аннотации оригинала
Livestock and their ectoparasites are involved in the epidemiology of several zoonotic diseases. Studies regarding the molecular detection of infectious agents in ticks from Northwestern Algeria are scarce. Thus, the presence of spotted fever group Rickettsia spp., Anaplasmataceae microorganisms and Coxiella burnetii was investigated in ticks collected from …

Fatal disseminated cryptococcosis and concurrent ehrlichiosis in a dog.

Laboratory findings in an adult bull terrier presented with a history of anorexia and weight loss included the following: severe anaemia, leukocytosis, neutrophilia, lymphopaenia, thrombocytopaenia, Ehrlichia canis morulae in monocytes, hypergammaglo-bulinaemia, a bleeding tendency, icterus and proteinuria. In addition, a high Haemobartonella canis parasitaemia, non-encapsulated yeasts on urinalysis and a localised Demodex canis infestation were present. Treatment for ehrlichiosis was initiated but the dog died. Lesions found were a severe cryptococcal granulomatous pneumonia and cryptococcal

Novel genotypes of Hepatozoon spp. in small mammals, Brazil.

BACKGROUND: Small mammals (rodents and marsupials) have been poorly explored for the occurrence of apicomplexan (genus Hepatozoon and genera of the order Piroplasmorida) and Anaplasmataceae agents in Brazil. Thus, this study investigated the occurrence of Hepatozoon spp., Piroplasmorida, and Anaplasmataceae agents in small mammals in seven forest fragments in Brazil. METHODS: During 2015-2018, small mammals were captured in six forest fragments in the State of São Paulo (Cerrado and Atlantic Forest biomes) and one fragment in the State of Mato Grosso do Sul (Pantanal biome). Mammal blood, liv…

Molecular Prevalence of Anaplasma marginale and Ehrlichia in Domestic Large Ruminants and Rhipicephalus (Boophilus) microplus Ticks From Southern Luzon, Philippines.

Anaplasmosis and ehrlichiosis are tick-borne rickettsial diseases that cause significant economic losses in the livestock industry worldwide … nd 108 water buffalo and 195 tick samples were subjected to nested PCR targeting the groESL gene of Anaplasmataceae. Positive samples were further subjected to another nested PCR and conventional PCR to amplify the A. marginale groEL gene and the Ehrlichia dsbA gene, respectively. Selected A. marginale-positive samples were also subjected to nested PCR targeting …

Bartonella spp. in different species of bats from Misiones (Argentina).

The aim of this study was to detect vector-borne pathogens (Anaplasmataceae family, Rickettsia genus, and Bartonella genus) in bats from Misiones (Argentina). Thirty-three specimens were captured over 8 days using mist nets. Twenty (60.6%) blood samples were positive (11/13 Artibeus lituratus, 4/10 Desmodus rotundus, 4/8 Carollia perspicillata, and 1/2 Myotis nigricans) by PCR for the gltA gene fragment of Bartonella. All samples were negative by PCR for the Anaplasmataceae family and Rickettsia genus. The phylogenetic analysis showed seven Bartonella genotypes. The three genotypes obtained fr…

Omentalisation of perinephric pseudocysts in a cat.

An 11-year-old male domestic shorthaired cat was presented with behavioural disturbances and abdominal distension of two days' duration. Haemobartonella felis was found on routine haematology and serum biochemistry showed mild azotaemia. Abdominocentesis revealed a transudate. Bilateral perinephric fluid accumulations were observed on ultrasonography and chronic nephrosclerosis was diagnosed on needle biopsies of the kidney. A celiotomy with resection of the major portion of both cyst walls was performed. The omentum was extended along the floor of the abdomen, across the ventral aspect of bot

Cytokine responses of immunosuppressed and immunocompetent patients with Neoehrlichia mikurensis infection.

PURPOSE: The tick-borne bacterium Neoehrlichia mikurensis causes the infectious disease neoehrlichiosis in humans. Vascular endothelium is one of the target cells of the infection. Neoehrlichiosis patients with compromised B cell immunity present with more severe inflammation than immunocompetent patients. The aim of this study was to compare the cytokine profiles of immunocompetent and immunosuppressed patients with neoehrlichiosis. METHODS: Blood samples from Swedish and Norwegian immunosuppressed (N = 30) and immunocompetent (N = 16) patients with neoehrlichiosis were analyzed for the leve

[Tick-borne CandidatusNeoehrlichiamikurensis was the cause of fever in a haematological patient].

A 77-year-old woman had a history of mantle cell lymphoma, splenechtomy and rituximab-treatment. For six months she had fever, night sweats and weight loss. Thorough investigations did not reveal the cause of the fever, and empiric antibiotics had no effect. Eventually she developed an erythema nodosum-like rash on both legs. A biopsy was sent for 16S rRNA PCR, which was positive for Candidatus Neoehrlichia mikurensis. She was treated with doxycycline with resolution of all symptoms. This is the first case report of neoehrlichiosis in Denmark, and the first case diagnosed on a skin biopsy.

Neoehrlichia mikurensis-An emerging opportunistic tick-borne infection in immunosuppressed patients.

BACKGROUND: Neoehrlichia mikurensis (N. mikurensis) is a newly discovered tick-borne pathogen that can inflict life-threatening illness in immunocompromised patients. N. mikurensis infection is only detectable by polymerase chain reaction (PCR)-based methodologies. We describe three distinct clinical manifestations of N. mikurensis infection (neoehrlichiosis) in Danish patients receiving B-lymphocyte-depleting therapy, rituximab, for underlying hematological, rheumatological, or neurological disorders. All three patients went through a protracted pre-diagnostic period. METHODS: N. mikurensis

Neoehrlichia mikurensis in Ticks and Tick-Bitten Persons, Sweden and Finland, 2008-2009.

By using PCR testing, we found Neoehrlichia mikurensis DNA in 1.1% of ticks removed from persons in Sweden and Finland. Symptoms developed in 2 immunocompetent persons. Despite low transmission risk, infection can occur after short tick attachment. Our findings highlight the need to consider N. mikurensis in patients with unexplained symptoms after tick bite.

Hematotropic parasites of translocated raccoons in the southeast.

Ninety-four raccoons (Procyon lotor) from 6 southeastern states were examined for hematotropic parasites, to evaluate the carrier potential of these animals as they relate to translocation and release for hunting purposes. Four species of hematotropic parasites were identified, viz, Babesia procyonis, Haemobartonella procyoni, Hepatozoon procyonis, and Trypanosoma cruzi. Lesions in infected raccoons were associated only with H procyonis. Babesia procyonis was enzootic in populations of raccoons used as sources for exportation and in raccoons resident in typical release areas. Haemobartonella p

[The course of trypanosoma cruzi infection in nonsplenectomized SPE rats with and without Haemobartonella muris infection (author's transl)].

Rats were infected with H. muris from the first to the second week of their life. Four weeks later 20 of the infected rats were inoculated with 1.5 x 10(5) T. cruzi. Control animals were given the same number of parasites. In both experimental groups no hemoflagellate could be seen in blood smears four weeks after infection. The comparison of the course of infection of T. cruzi in rats with and without H. muris was made using t- and Wilcoxon-Test for Pair Differences. Rats with H. muris infections showed a low development of T. cruzi up to the 16th day of infection with this flagellate (P less

Detection of Ehrlichia spp., Candidatus Neoehrlichia sp. (FU98) and Anaplasma phagocytophilum in red foxes (Vulpes vulpes) in Germany.

Vector-borne diseases pose a growing challenge to public health. Effective surveillance, interdisciplinary cooperation in line with the One Health approach, and prevention and control strategies are therefore essential to reduce the risk of future outbreaks and burden of disease in the long term. Identifying and investigating sentinels can help in this regard. In this study, 537 red fox (vulpes) spleen samples from three regions in Germany (Berlin, Brandenburg, Arnsberg administrative region) were tested for Anaplasmataceae and Rickettsia spp. using PCR. Only 3% of the samples (n = 15) tested …

Anaplasma platys and Rickettsia massiliae in Rhipicephalus sanguineus sensu stricto ticks collected on dogs in the Patagonian region of Argentina.

The aim of this study was to examine the presence of tick-borne rickettsial bacteria in Rhipicephalus sanguineus sensu stricto ticks collect … ickettsia. Thirty-three tick pools were tested by different PCR assays of which 3 were positive for Anaplasmataceae bacteria. From the 3 Anaplasmataceae positive samples, 2 partial 16S rDNA sequences were generated and belonging to Anaplasma platys, the causative agent of canine cyclic thrombocytopenia. Two tick samples were positive in Rickettsia specific PCR as …

Detection and genetic diversity of Neoehrlichia mikurensis in rodents from central and southern Shanxi, China.

Neoehrlichia mikurensis is vector-borne gram-negative intracellular bacteria that has a wide range of hosts, and are recognized as emerging human pathogens. This study aimed to investigate the prevalence and genetic characteristics of N. mikurensis infections in rodents from central and southern of Shanxi Province, China. The rodents were captured, and the liver, spleen and kidney were collected for N. mikurensis detection and identification by 16 S rRNA and groEL genes sequencing. N. mikurensis was detected in Apodemus agrarius from Yangquan and Eothenomys inez from Yuncheng, with a positivit

"Candidatus Neoehrlichia mikurensis" in Ixodes ricinus ticks collected near the Arctic Circle in Norway.

BACKGROUND: "Candidatus Neoehrlichia mikurensis" is a gram-negative bacterium belonging to the family Anaplasmataceae that, in Europe, is transmitted by Ixodes ricinus ticks. "Candidatus N. mikurensis" can cause a severe systemic inflammatory syndrome, neoehrlichiosis, mostly in persons with other underlying diseases. To date, "Ca. N. mikurensis" has been found in ticks in different countries in Asia and Europe, but never as far north as at the Arctic Circle. METHODS: A total of 1104 I. ricinus ticks collected from vegetation and from animals in northern Norway (64-68°N) were analysed for the…

Susceptibility of the female reproductive tract of mice to Tyzzer's organism.

Susceptibility of the reproductive tract of ICR adult female mice to Tyzzer's organisms was examined by intravenous and intravaginal inoculation at various stage of pregnancy. After intravenous inoculation, the uterus was most severely affected when inoculation was made at the midpregnancy. Severe involvement of the uterus was also seen after intravaginal inoculation made either at late-pregnancy or shortly before and after parturition. While non-pregnant female mice were less susceptible to intravenous or intravaginal inoculation, the growth of organisms in the uterine epithelium was recogniz

Update on Tick-Borne Bacterial Diseases in Travelers.

PURPOSE OF REVIEW: Ticks are the second most important vectors of infectious diseases after mosquitoes worldwide. The growth of international tourism including in rural and remote places increasingly exposes travelers to tick bite. Our aim was to review the main tick-borne infectious diseases reported in travelers in the past 5 years. RECENT FINDINGS: In recent years, tick-borne bacterial diseases have emerged in travelers including spotted fever group (SFG) rickettsioses, borrelioses, and diseases caused by bacteria of the Anaplasmataceae family. African tick-bite fever, due to Rickettsia af…