Результаты поиска

Abstracts from the 6th Annual Conference of Emirates Society of Internal Medicine (ESIM) 2025.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Ethnoveterinary contemporary knowledge of farmers in pre-alpine and alpine regions of the Swiss cantons of Bern and Lucerne compared to ancient and recent literature - Is there a tradition?

ETHNOPHARMACOLOGICAL RELEVANCE: The term "traditional" is well established in European (human) medicine and even appears in recent European … plant species belonging to 46 botanical families. Plants of the families Asteraceae, Lamiaceae and Rosaceae were most frequently used. Matricaria recutita L., Calendula officinalis L., Quercus robur L., Thymus vulgaris L. and Symphytum officinale L. were the most frequently documented species. A total of 404 use reports (UR) were gathered for the 315 HSH …

First Report of Phyllosticta capitalensis causing leaf spot on Eriobotrya japonica in China.

Loquat (Eriobotrya japonica), a member of the Rosaceae family that has been widely grown in South China, is rich in triterpenoids and has numerous medicinal uses (Su et al. 2021). In August 2024, leaf spots on E. japonica were observed in Libo (25.4°N, 107.8°E) and Guanling (25.9°N, 105.6°E), Guizhou province of China with a disease incidence of 20%-40%. Leaf spots were initially yellow and gradually spread and turned dark brown. Fifteen symptomatic leaves were randomly collected from five fields. Leaves were cut into 4×4 mm pieces and disinfested with 75% ethanol for 30 s, 2% NaCIO solution f…

Antibacterial effects of blackberry extract target periodontopathogens.

BACKGROUND AND OBJECTIVE: Antimicrobial agents provide valuable adjunctive therapy for the prevention and the control of oral diseases. Limitations in their prolonged use have stimulated the search for new, naturally occurring agents with more specific activity and fewer adverse effects. Here we sought to determine the antibacterial properties of blackberry extract (BBE) in vitro against oral bacterial commensals and periodontopathogens. MATERIAL AND METHODS: The effects of whole and fractionated BBE on the metabolism of 10 different oral bacteria were evaluated using the colorimetric water-s

A case of Schöpf-Schulz-Passarge syndrome presented with widespread apocrine hidrocystomas showing variable clinical features.

Dear Editor, Genodermatoses are usually diagnosed in early childhood but diagnosis may be delayed in rare cases. Schöpf-Schulz-Passarge synd … was also associated. However, other rare supporting features, such as eccrine syringofibroadenoma, rosacea-like facial erythema, hypoplastic areolae and nipple, and ocular involvement were not observed (4-7). The patient had also a basal cell carcinoma on the nose (Fig. 2c) which has been occasionaly reported in SSPS (4). Furthermore, a 9 × 9 cm soft, su …

Primary cutaneous lymphoma patients seen at a referral dermatological centre in 1 year: A single-centre observational retrospective cohort study of the diagnoses and staging, comorbidities and associated symptoms, treatment performed and clinical course.

IMPORTANCE: Primary cutaneous lymphomas (PCL) are rare diseases, but the indolent course makes their prevalence high. Although there are many treatment options, no hierarchy is recommended. OBJECTIVE: To identify the burden of PCL and describe clinical-pathologic features; associated comorbidities; analyse treatment approaches in real-life and the parameters associated with the achievement of complete response (CR). DESIGN, SETTING AND PARTICIPANTS: In this study, all the PCL patients (384 patients) consecutively seen at the Dermatologic Clinic of the University of Turin from January 1, 2019

Совпадение в полном тексте источника
… Dermatologic comorbidities were more frequently psoriasis (19 patients), atopic dermatitis (3), rosacea (3), seborrheic dermatitis (2), bullous pemphigoid (2). Primary malignant skin cancers were basal cell carcinoma in 15 (39.5%) and melanoma in 11 patients (28.9%). …

Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination.

Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its physiological role is much larger and encompasses very different processes ranging from facilitation of iron absorption through involvement in hormones and carnitine synthesis for important roles in epigenetic processes. Contrarily, high doses act as a pro-oxidant than an anti-oxidant. This may also be the reason why plasma levels are meticulously regulated on the level of absorption and excretion in the kidney. Interestingly, most cells contain vitamin C in millimolar concentrations, which is much highe

Совпадение в полном тексте источника
… . | Grossulariaceae | Black currant | 148–310 a | [ 24 ] 60–250 d | [ 32 ] Actinidia deliciosa (A.Chey.)C.F.Liang et A.R.Ferguson | Actinidiaceae | Kiwi | 60–78 a | [ 11 , 25 ] Fragaria virginiana Duchesne | Rosaceae | Strawberry | 65 a | [ 25 ] Citrus x sinensis (L.)Osbeck. | Rutaceae | Orange | 41– … 58 a | [ 11 , 25 , 44 ] Citrus limon (L.)Osbeck. | Rutaceae | Lemon | 30 d 31 a | [ 44 , 45 ] Citrus reticulata Blanco | Rutaceae | Common mandarin | 27 a | [ 25 ] Malus domestica Borkh. | Rosaceae | Apple | 11–35 a | [ 46 ] Pyrus communis L. | Rosaceae | Pear | 7–29 a | [ 46 ] Vegetables | | | | …

Adverse Reaction to Cetuximab, an Epidermal Growth Factor Receptor Inhibitor.

Dear Editor, Inhibition of the epidermal growth factor receptor (EGFR) is a new strategy in treatment of a variety of solid tumors, such as … ocols. Therapy is mainly based on clinical experience and follows the standard treatments for acne, rosacea, xerosis, paronychia, and effluvium. The therapeutic approach for papulopustular exanthema includes topical and systemic antibiotics for their antimicrobial as well as anti-inflammatory effect, sometimes in combination with topical steroids. Topical …

Genes, Gene Loci и их влияние на иммунную систему развития множественных склерозов: систематический обзор.

Множественный склероз (MS) — это состояние, характеризующееся повреждением центральной нервной системы (CNS), которое вызывает у пациентов когнитивные и физические трудности. Хотя болезнь имеет сложную этиологию, которая включает генетические и экологические факторы, мало что известно о роли генов и генологов в ее развитии. Цели: Данное исследование было направлено на изучение воздействия генов и ген-лочи на иммунную систему в ходе разработки MS. Мы стремились определить основные гены и генные лочи, которые играют роль в патогенезе MS, и последствия для будущей разработки подходов к клиническо

Совпадение в полном тексте источника
… Genetic factors that are shared between MS and other autoimmune conditions, such as rosacea, can also affect disease severity and progression [ 64 ]. … Clustering of autoimmune diseases in patients with rosacea. J. Am. Acad. Dermatol. 2016;74:667–672.e1. doi: 10.1016/j.jaad.2015.11.004. 59. Tranah G.J., Santaniello A., Caillier S.J., D’Alfonso S., Boneschi F.M., Hauser S.L., Oksenberg J.R. …

Thalidomide attenuates radiation-induced apoptosis and pro-inflammatory cytokine secretion in oral epithelial cells by promoting LZTS3 expression.

Radiation-induced oral mucositis (RIOM) is a prevalent oral complication that occurs in individuals undergoing radiotherapy or radiation treatment for head and neck tumors. The presence of oral mucosal rupture and ulcerative lesions, which are the defining features of this condition, can significantly affect the quality of life of patients. Additionally, it can interfere with tumor therapy and contribute to an unfavorable prognosis. Current evidence suggests that cellular inflammation and programmed cell death are important factors in disease development. Moreover, thalidomide (THD) has been r

Совпадение в полном тексте источника
… Chen M Xie H Chen Z Xu S Wang B Peng Q Thalidomide ameliorates rosacea-like skin inflammation and suppresses NF-κB activation in keratinocytes Biomed Pharmacother 2019 116 109011 10.1016/j.biopha.2019.109011 31132668 Chen M, Xie H, Chen Z, Xu S, Wang B, Peng Q, et al. … Thalidomide ameliorates rosacea-like skin inflammation and suppresses NF-κB activation in keratinocytes. Biomed Pharmacother. 2019;116:109011. 31132668 10.1016/j.biopha.2019.109011 12. …

Patient and Physician Preferences for Acute Myeloid Leukemia Maintenance Treatments Following Hematopoietic Stem Cell Transplantation.

PurposeThis study assessed and compared preferences for treatment attributes of maintenance therapies post-hematopoietic stem cell transplantation (HSCT) in patients with acute myeloid leukemia (AML) and in physicians who treat these patients.Patients and methodsPatients with AML post HSCT and physicians from the United States, United Kingdom, Canada, and Australia (physicians only) completed a web-based discrete choice experiment (DCE). The DCE used inputs identified via a targeted literature review and qualitative interviews to ascertain relevant treatment attributes and associated levels. S

Совпадение в полном тексте источника
… (40.0) $2001 to $5000 11 (27.5) More than $5000 5 (12.5) Unknown/not sure 3 (7.5) Notes : a Among patients who provided a response. b Other comorbidities include arthritis, osteoporosis, high cholesterol, skin issues, migraine, memory loss, hearing loss, pain, cognitive impairment, hyperlipidemia, rosacea … Table 2 Patient Baseline Demographics and Clinical Characteristics Notes : a Among patients who provided a response. b Other comorbidities include arthritis, osteoporosis, high cholesterol, skin issues, migraine, memory loss, hearing loss, pain, cognitive impairment, hyperlipidemia, rosacea, emphysema …

Талидомид взаимодействует с воспалением в идиопатическом фиброзе легких.

" Трагедия Талидомида " является важной вехой в истории фармацевтической промышленности. Несмотря на ограниченные клинические испытания, прилагаются постоянные усилия по изучению Талидомида в качестве лекарства от рака и подстрекательских заболеваний, таких, как ревматуидный артрит, проказа, и COVID-19. В рамках этого обзора основное внимание уделяется возможностям борьбы с воспалением путем повторного использования талидомида для лечения идиопатического фиброза легких (ИПФ). Статьи были найдены в базе данных Scopus, сортированы и рассмотрены отдельные статьи. Содержание включает в с

Совпадение в полном тексте источника
… The transcript BCN2 is responsible for simulating fibrosis signalling in tissues (Bobowski-Gerard et al. 2022 ) 40 Thalidomide effectively lowered skin lesions, inflammation and fibrosis related factors in rosacea mice model (Kang et al. 2022 ) Table 1 Preclinical and clinical trials performed to assess … The transcript BCN2 is responsible for simulating fibrosis signalling in tissues | (Bobowski-Gerard et al. 2022 ) 40 | Thalidomide effectively lowered skin lesions, inflammation and fibrosis related factors in rosacea mice model | (Kang et al. 2022 ) Currently approved drugs for IPF are pirfenidone …

Autologous Hematopoietic Cell Transplant as an Effective Treatment Modality for Systemic Sclerosis and Multiple Myeloma.

Systemic sclerosis (SSc) is a multi-system disease characterized by a dysregulated immune system. Autologous hematopoietic cell transplantation (AHCT) is the only treatment that has been shown to confer significant benefit in controlling disease and improving survival for patients with SSc. A diagnosis of multiple myeloma (MM) after the diagnosis of SSc is rare and optimal treatment in such cases remains unclear. We here report a case of a female patient who was diagnosed with MM while she was undergoing evaluation for AHCT due to SSc. A novel conditioning regimen for AHCT, with therapeutic ef

Совпадение в полном тексте источника
… Thalidomide attenuates skin lesions and inflammation in rosacea-like mice induced by long-term exposure of LL-37 . Drug Des Devel Ther . 2022 ; 16 : 4127 – 4138 . doi: 10.2147/DDDT.S393122 PMC9724583 36483458 …

Вероятное метформирование, связанное с эритемой: доклад о деле и практическая ссылка на оценку причинно-следственной связи.

Метформин - это первая линия терапии для типа 2 В целом считается, что сахарный диабет имеет благоприятную характеристику безопасности и терпимости. Несмотря на редкие, резкие негативные реакции на метформин являются разнообразными, при этом особенно редко встречается многоформовая эритема (ЭМ). Мы сообщаем о случае 51-year-old человек, разработавший общие митоидные повреждения кожи с масштабированием и мягким приритом ten через несколько дней после инициирования метроформина (500 мг дважды в день) для вновь поставленного типа 2 диабет. Он также получал аспирин и аторвастатин для острого цереб

Совпадение в полном тексте источника
… vasculitis), exclusion of other causes Lenfestey (2012) ( 19 ) 71/M Pseudoporphyria Tense hemorrhagic bullae on dorsal hands, skin fragility, mild scarring 4 months 2 months No milia, hypertrichosis, sclerosis, or calcification; normal urine porphyrins Exclusion of other etiologies Mumoli (2014) ( 22 ) 29/F Rosacea-like …

Belantamab mafodotin, carfilzomib, lenalidomide и дексаметазон для рецидива или рефракта множественной миеломы.

Резюме Belantamab mafodotin (Belamaf), антитела-наркотики, направленные против антигена ячеек B-клеток, продемонстрировало активность одного агента в повторной/охлажденной миеломе (RRMM), но связано с окулярной токсичностью. Это фазы 1/2 в ходе исследования была проведена оценка безопасности и предварительной эффективности использования беналафа 8 Недели в сочетании с карфилзомидом, линалидомидом и дексаметасоном (KRd-b) у пациентов с RRMM. Пациенты, имеющие право на получение помощи, по крайней мере, 1 :: предыдущая терапия и не продвинулась по полной дозе леналидомида. На стадии " доза-

Совпадение в полном тексте источника
… . § Petechiae, painless bumps on inside of lips, skin peeling on hands, rosacea, and skin graft for cellulitis. ǁ Melena, light colored stools, and 24-hour gastrointestinal virus. ¶ Prostate hypertrophy and rectal carcinoma. # Elective implanted port placement and laryngeal biopsy. Table 2. … . § Petechiae, painless bumps on inside of lips, skin peeling on hands, rosacea, and skin graft for cellulitis. ǁ Melena, light colored stools, and 24-hour gastrointestinal virus. ¶ Prostate hypertrophy and rectal carcinoma. # Elective implanted port placement and laryngeal biopsy. …

Hematological indices as indicators of silent inflammation in achalasia patients: A cross-sectional study.

Complete blood count (CBC)-derived parameters such as neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), eosinophil-to-lymphocyte (ELR) ratio, and platelet-to-lymphocyte ratio (PLR) are sensitive markers of occult inflammation and disease activity for systemic lupus erythematosus, rheumatoid arthritis, psoriasis, esophageal cancer, etc. We assessed NLR, PLR, MLR, and ELR as indicators of inflammation in achalasia patients.This cross-sectional study included 103 achalasia patients and 500 healthy blood donor volunteers (HD). Demographic, clinical and laboratory informatio

Совпадение в полном тексте источника
… Finally, the presence of chronic inflammatory conditions (i.e., asthma, allergic rhinitis, gout, and rosacea) was recorded. CBC parameters used in the study were the latest laboratory findings recorded prior to surgical intervention. …

Management and outcomes of proteasome inhibitor associated chalazia and blepharitis: a case series.

BACKGROUND: The purpose of this case series was to further characterize proteasome inhibitor associated chalazia and blepharitis, to investigate outcomes of different management strategies, and to propose a treatment algorithm for eyelid complications in this patient population. METHODS: This retrospective case series included sixteen patients found to have chalazia and/or blepharitis while receiving proteasome inhibitors for plasma cell disorders at Mount Sinai Hospital in New York, NY from January 2010 through January 2017. Main outcomes were complete resolution of eyelid complications and

Совпадение в полном тексте источника
… No patients had a history of preexisting seborrheic dermatitis, rosacea, or prior ocular infections. Of the fourteen patients with chalazia, eleven (79%) experienced two or more concurrent lesions. …

Neurotoxicity associated with cancer chemotherapy: the first study in the Palestinian healthcare system.

BackgroundChemotherapy-induced neurotoxicity is a significant concern in cancer treatment as it adversely affects treatment outcomes. However, research on this subject within the Palestinian healthcare system is limited. This study aimed to evaluate the prevalence, clinical manifestations, and associated factors of neurotoxicity in cancer patients receiving chemotherapy in Palestine.MethodsThis retrospective cohort study included 196 cancer patients who underwent chemotherapy at multiple hospitals across Palestine. Data on patient demographics, cancer characteristics, chemotherapy regimens, an

Совпадение в полном тексте источника
… for no apparent reason | 83 (42.3) | 27 (13.8) | 33 (16.8) | 28 (14.3) | 25 (12.8) 62 | Appetite swings | 66 (33.7) | 31 (15.8) | 37 (18.9) | 32 (16.3) | 30 (15.3) 63 | Frequent muscle aches, cramps, unusual sharp sudden pains | 95 (48.5) | 37 (18.9) | 26 (13.3) | 13 (6.6) | 25 (12.8) 64 | Rashes or rosacea …