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A Review on the Multidisciplinary Approach for Cancer Management in the Eastern Mediterranean Region: A Focus on Nutritional, Lifestyle and Supportive Care.

Cancer is one of the leading causes of global morbidity and mortality and one of the most challenging global health conditions, impacting the lives of millions every year. The Eastern Mediterranean Region (EMR) is not on track to achieve the sustainable development goal (SDG) target 3.4 which aims to reduce premature mortality (i.e., before the age of 70 years) for non-communicable diseases (NCDs), including cancer, by a third by year 2030; instead, it is projected that the EMR will experience the least progress towards achieving this target. This review therefore highlights the importance of

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… Incorporating complementary therapies such as ginger tea, deep breathing, acupressure bracelets and other relaxation approaches such as reading a book, listening to music and meditating, to aid in the management of symptoms. …

The use of smart technologies for enhancing palliative care: A systematic review.

IntroductionWith the rapid advancement of technology, smart technologies have permeated various sectors, including palliative care in healthcare. Based on the available literature, similar studies have elucidated the application of individual and isolated smart technologies in palliative care, with their benefits, and limitations. This research, therefore, focuses on the conceptualisation of various smart technologies and makes holistic recommendations on the effective and efficient use of smart technologies in healthcare to enhance palliative care.PurposeThe purpose of this study is to system

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… Participants emphasised the soundscapes, the natural habitats with their flora and fauna, the soothing music, and the water as important immersive elements. | Future experiences must have simple interfaces and minimise difficulties like resolution, discomfort, and complicated controls that have been …

2026 Приложение к резюме Международного конгресса

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Integrating Palliative Care into Oncology Care Worldwide: The Right Care in the Right Place at the Right Time.

Opinion statementWhile the benefits of early palliative care are indisputable, most of the current evidence has emerged from resource-rich settings in urban areas of high-income countries, with an emphasis on solid tumors in outpatient settings; this model of palliative care integration is not currently scalable internationally. A shortage of specialist palliative care clinicians means that in order to meet the needs of all patients who require support at any point along their advanced cancer trajectory, palliative care must also be provided by family physicians and oncology clinicians who req

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… Interdisciplinary care is a key component of the support provided in inpatient hospices or palliative care units, provided by specialized palliative care nurses, physicians, social workers, spiritual care providers, physiotherapists, occupational therapists, music therapists, art therapists, pharmacists …

Preclinical B cell depletion and safety profile of a brain-shuttled crystallizable fragment-silenced CD20 antibody.

BACKGROUND: The blood-brain barrier (BBB) presents a major challenge for the development of monoclonal antibody (mAb)-based therapies for brain disorders. To improve the likelihood of success of such therapies, Roche Brainshuttle technology utilizes a single anti-transferrin receptor 1 (TfR1)-antigen-binding antibody fragment linked to a therapeutic antibody, allowing engagement with TfR1 to transport the therapeutic antibody into the brain via receptor-mediated transcytosis. METHODS: We compared Fc-silenced and Fc-competent variants of the Brainshuttle and the parental (non-shuttled) type II

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… studies, mice (up to six per cage [type IV macrolon boxes with autoclaved sawdust bedding]) were kept in a climate‐controlled animal room under periodic bacteriologic control, at 22 ± 2°C (monitored), at 40–80% humidity (monitored), with fluorescent lighting on a 12 h light/dark cycle, with background music …

Survival protection of patients undergoing hematopoietic stem cell transplantation: grounded theory.

PurposeFor patients with blood malignancies, hematopoietic stem cell transplantation (HSCT) is a significant challenge. These patients have hope to be completely cured after the transplantation, but deal with the dread of dying at the same time. This study presents a deep understanding of the psychological process of the treatment including perception, emotion, interactions, and its consequences in patients undergoing HSCT.MethodsThis study utilized a qualitative method based on the Strauss and Corbin Approach toward the grounded theory. The research population comprised all patients undergoin

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… Self-control One of the measures that patients take to preserve their spirit, is planning for the time of hospitalization including watching movies and series, listening to music, dancing, finding entertainment, making a daily journal, praying, distracting themselves, hiding their discomfort from others …

Novel therapeutic approaches for pulmonary fibrosis.

Pulmonary fibrosis represents the end stage of a number of heterogeneous conditions and is, to a greater or lesser degree, the hallmark of the interstitial lung diseases. It is characterized by the excessive deposition of extracellular matrix proteins within the pulmonary interstitium leading to the obliteration of functional alveolar units and in many cases, respiratory failure. While a small number of interstitial lung diseases have known aetiologies, most are idiopathic in nature, and of these, idiopathic pulmonary fibrosis is the most common and carries with it an appalling prognosis - med

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… Prospective, double-blinded randomized placebo-controlled trial; ambrisentan vs. placebo, currently recruiting, total planned n = 600 | Primary end points: time to disease progression or death, event driven over 4 years | Terminated at interim analysis stage due to lack of efficacy Macicentan | See text | MUSIC … An additional trial investigating the efficacy of endothelin antagonists in IPF is currently ongoing: the MUSIC trial (Actelion, Switzerland) is a randomized double-blinded placebo-controlled trial designed to examine the effect of the dual endothelin receptor antagonist, macicentan, on FVC, and has …

Development of a quality indicator set for day hospices in Germany - a multi-stage, quality-assured review of German guidelines and quality indicator sets.

BackgroundDay hospices are an emerging component of outpatient palliative care in Germany. However, a standardized quality management system utilizing defined quality indicators has not yet been implemented. This study aimed to develop a new set of quality indicators for day hospices.MethodsThrough a multi-phase, quality-assured review, we screened validated quality indicators from German-language S3 guidelines and established quality indicator sets, including the Quality Indicator System for Outpatient Care (QISA) and Outpatient Quality Indicators and Key Figures (AQUIK) based on defined crit

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… These include specific care measures, the evaluation of special support services (e.g., music therapy, breathing therapy, volunteer helpers), and day-structuring activities (e.g., shared meals, walks). …

Неучтенная роль экгасомов в когнитивно-моторной нейрореабилитации: систематический обзор.

Эксгармии — это новые инструменты когнитивно-моторной нейрореабилитации, но их воздействие на взрослых с неврологическими условиями еще недостаточно изучено. В рамках этого систематического обзора были изучены исследования, полученные из PubMed, Scopus, Embase и Web of Science, с оценкой воздействия экзотомов на двигательные и когнитивные результаты. К числу приемлемых исследований относятся случайные контролируемые испытания (РСТ), не связанные с РСТС и экспериментальные проекты. Протокол был зарегистрирован на сайте ПРОСПЕРО (CRD420250655053) и составлен в соответствии с руководящими принцип

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… mixed forms; inclusion criteria: age ≥65 years, diagnosed with MNCD, able to perform standing exercises | Dividat Senso exergame system: pressure-sensitive step training platform | 8 weeks, 3 sessions/week, 15 min of exergaming (intervention) Control: 8 weeks, 3 sessions/week, 15 min of listening to music …

Review of the Immune Checkpoint Inhibitors in the Context of Cancer Treatment.

Checkpoint proteins are an integral part of the immune system and are used by the tumor cells to evade immune response, which helps them grow uncontrollably. By blocking these proteins, immune checkpoint inhibitors can restore the capability of the immune system to attack cancer cells and stop their growth. These findings are backed by adequate clinical trial data and presently, several FDA-approved immune checkpoint inhibitors exist in the market for treating various types of cancers, including melanoma, hepatocellular, endometrial, lung, kidney and others. Their mode of action is inhibition

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… Immune surveillance of human cancer: If the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune? Tissue Antigens. 2010;75:1–8. doi: 10.1111/j.1399-0039.2009.01401.x. 2. Jhunjhunwala S., Hammer C., Delamarre L. …

The Effect of Exercise on Pain in People with Cancer: A Systematic Review with Meta-analysis.

IntroductionCancer-related pain is common and undertreated. Exercise is known to have a pain-relieving effect in non-cancer pain.ObjectivesThis systematic review aimed to evaluate (1) the effect of exercise on cancer-related pain in all cancers, and (2) whether the effect of exercise differed according to exercise mode, degree of supervision, intervention duration and timing (during or after cancer treatment), pain types, measurement tool and cancer type.MethodsElectronic searches were undertaken in six databases to identify exercise studies evaluating pain in people with cancer, published pri

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… Non-pharmacological pain management strategies, including pain educational programmes to reduce patient-related barriers and to improve knowledge and communication with healthcare professionals [ 14 , 15 ], and psychosocial interventions (involving relaxation techniques, cognitive–behavioural therapy, music …

Prevalence of unmet supportive care needs reported by individuals ever diagnosed with cancer in Australia: a systematic review to support service prioritisation.

PurposeImproved health outcomes for individuals ever diagnosed with cancer require comprehensive, coordinated care that addresses their supportive care needs. Implementing interventions to address these is confounded by a lack of evidence on population needs and a large pool of potential interventions. This systematic review estimates the point prevalence of different supportive care needs stratified by the tool used to measure needs and cancer type in Australia.MethodsWe searched MEDLINE, Embase, and Scopus from 2010 to April 2023 to identify relevant studies published on the prevalence of su

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… Most reviews focused on exercise interventions, whilst others included acupuncture, Chinese medicine, complementary and alternative medicines, diet, psychological therapy, expressive writing, art therapy, music therapy, massage, education, and pharmacological interventions [ 23 ]. …

Effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer: A systematic review and meta-analysis.

BackgroundTelehealth is being integrated with palliative care for patients with advanced cancer to improve access to specialized palliative care. However, its effectiveness and implementation requirements in palliative care remain unclear.AimThis study evaluates the effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer.DesignThis was designed as a systematic review and meta-analysis with narrative synthesis (registered; CRD42024581786). The effects on patients' quality of life, symptom burden, and depression were analyzed using a rando

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… Some studies encompassed additional team members, such as pharmacist, psychologists, social workers, music therapists, physiotherapists, and chaplains. 49 , 51 , 69 , 72 Physicians played a central role, particularly in video consultations. …

Proceedings of Réanimation 2020, the French Intensive Care Society International Congress.

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Management of Myeloproliferative Neoplasms: An Integrative Approach.

Myeloproliferative neoplasms (MPNs) are chronic blood cancers characterized by overproduction of blood cells, leading to increased thrombotic and ischemic risk. Patients frequently experience symptoms including fatigue, abdominal discomfort, and complications from thrombotic events, which significantly impact the quality of life (QoL). Many patients inquire about complementary and integrative medicine (CIM) approaches, including nutritional interventions and supplements, creating opportunities for healthcare providers to engage in meaningful discussions guided by the principle of safety. This

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… Other Integrative Approaches for MPNs Integrative therapies, such as massage, music therapy, art therapy, Aryuveda, healing touch, and other therapies, are increasingly recognized for their potential to alleviate symptom burden and enhance QoL in patients with cancer. …

Регулирующие расстройства и качество жизни у пациентов с травматологической и трахеотической каннулой: обзор.

ВВЕДЕНИЕ: Операция по Трахеостомии (TCT) и последующее включение трахеиальной каннулы (TC) сопряжены с рядом физических, коммуникативных и психологических изменений для пациента. В этих клинических ситуациях часто наблюдаются такие расстройства настроения и расстройства, как болезненное беспокойство, депрессия и стресс, что сказывается на качестве жизни (QoL) и процессе реабилитации. Цель этого обзора состоит в изучении исследований, содержащихся в литературе по расстройствам регулирования (АЖД) у пациентов с ТХТ или ТЦ, и того, как это влияет на их QOL в ходе процесса реабилитации. МЕТОДЫ: Ис

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… It involved a secondary analysis of data derived from a parent study that explored the impact of music listening on anxiety. | Study Design: Uncontrolled Experimental Study. Size: 166 patients. Age: 18 years or older. Sex: not specificated. …

Patient-Centered Insights on Treatment Decision Making and Living with Acute Myeloid Leukemia and Other Hematologic Cancers.

Expectations relating to treatment and survival, and factors influencing treatment decisions are not well understood in adult patients with acute myeloid leukemia. This study analyzed combined findings from a targeted literature review with patient-reported information shared on YouTube to further understand patient perspectives in hematologic cancers and, in particular, acute myeloid leukemia. The targeted literature review included articles concerning patient (aged ≥ 18 years) experiences or perspectives in acute myeloid leukemia or other hematologic cancers. YouTube video selection criteria

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… And I used to watch through the window, crying my eyes out and the nurses would say he has music in there. I didn’t need that.” …

Chronic stress: a fourth etiology in tumorigenesis?

Chronic stress, driven by persistent psychological, environmental, or physiological factors, is a prolonged heightened state of stress response that disrupts homeostasis. When unmanaged, it will lead to sustained negative emotions such as depression, loneliness, anxiety, and emotional adversity. This persistent emotional distress not only exacerbates mental health disorders but also poses significant risks to physical health. Increasing evidence suggests a strong link between chronic stress, stress-related hormones, and the rising incidence of malignancies. As a result, chronic stress might be

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… hematopoietic cell transplant Propranolol is effective in the treatment of multiple myeloma Propranolol Attenuate HCT-related stress NCT05429970 Ovarian cancer 35 NA Ongoing To determine the combination of propranolol and etodolac with mind-body resilience training/mind-body resilience training (MBRT) and music … transplant Propranolol is effective in the treatment of multiple myeloma | Propranolol Attenuate HCT-related stress NCT05429970 | Ovarian cancer | 35 | NA | Ongoing | To determine the combination of propranolol and etodolac with mind-body resilience training/mind-body resilience training (MBRT) and music …

Precision Oncology Clinical Trials: A Systematic Review of Phase II Clinical Trials with Biomarker-Driven, Adaptive Design.

Novel clinical trial designs are conducted in the precision medicine era. This study aimed to evaluate biomarker-driven, adaptive phase II trials in precision oncology, focusing on infrastructure, efficacy, and safety. We systematically reviewed and analyzed the target studies. EMBASE and PubMed searches from 2015 to 2023 generated 29 eligible trials. Data extraction included infrastructure, biomarker screening methodologies, efficacy, and safety profiles. Government agencies, cancer hospitals, and academic societies with accumulated experiences led investigator-initiated precision oncology cl

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… We commenced the extraction of articles based on exclusion criteria predefined by researchers after pre-screening as follows: (1) noncancer disease and non-human studies; (2) nonintervention clinical studies, including music therapy, psychological treatment, behavioral therapy, cognitive therapy, etc …

Quality indicators and patient outcome measures for palliative care in cancer patients: a systematic review.

IntroductionWith the exponential rise in global cancer incidence, the surge in demand for palliative care has outstripped capacity, limiting patients' access to quality and holistic palliative care, especially in low- and middle-income countries. Despite an upturn in research activity, evidence in palliative care remains limited, given its complexity as well as the shortage of standardised quality indicators (QIs) and patient outcome measures (POMs). The objective of this systematic review is to assess the QIs and POMs used to evaluate palliative care service on aggregated and individual level

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… Each non-medical palliative care program, such as art and music therapy, yoga, foot massage, haircut and body care, showed no significant differences between the group who received them and those who did not. | Inpatient Care | Process | APCU Length of stay, APCU discharge rate USA | Boyd et al [ 23 …