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VZV infection in pregnancy: a retrospective review over 5 years in Sheffield and discussion on the potential utilisation of varicella vaccine in prevention.

OBJECTIVES: To study retrospectively the epidemiology, demography and clinical issues related to varicella in pregnancy in a UK city over a … ies were recorded and the neonatology database used as a source of information regarding effects of chickenpox on the baby. RESULTS: The incidence of varicella infection in pregnancy was at least 6 per 10,000 deliveries. Nineteen pregnant women with varicella were admitted to hospital. Three had pneumonia. Infection occurred in the first pregnancy in a quar …

Severe complications of varicella in previously healthy children in Germany: a 1-year survey.

OBJECTIVE: Varicella is a common infectious disease, usually benign and self-limited, and complications are believed to be rare. The purpose of this study was to describe the epidemiology of severe varicella complications in immunologically healthy children in Germany. METHODS: Information on any admission of children with a severe complication associated with chickenpox was solicited throughout 1997 from all 485 pediatric hospitals in Germany using an established surveillance system. The case definition included nonimmunocompromised individuals who were up to 16 years of age and hospitalized…

Acyclovir treatment of disseminated varicella in childhood malignant neoplasms.

Primary varicella-zoster virus infection (chickenpox) in immunocompromised children is frequently associated with visceral dissemination and attendant high mortality. Eight children with malignant neoplasms and chickenpox with visceral involvement (seven with hepatitis, three with pneumonitis, two with encephalitis, and two with coagulopathy) were initially treated with intravenously (IV) administered vidarabine but demonstrated progressive visceral involvement. After three days of vidarabine treatment (two days for two patients), seven had rising serum SGPT levels, all eight had pneumonitis, …

[Benign acute ataxia in an adult with VZV infection].

In adults, neurological complications of VZV virus usually occur after herpes zoster infection in patients with AIDS. We report a case of acute and benign cerebellar ataxia after chickenpox in a patient without immunodeficiency.

[Membranous and pseudomembranous lesions of the esophagus (author's transl)].

Case reports are given of 2 patients with benign esophageal pemphigoids , of 1 patient with chickenpox involving the esophagus, an of 1 patient with carcinoma of the cardia. Differential diagnosis of membranous lesions of the esophagus is discussed on the basis of these case reports.

[Varicella associated with Lyell's syndrome after administration of sulfametin].

A case of chickenpox associated with Lyell syndrome, which appeared after the administration of sulfamethine, is reported. Quantitative determination of the immunoglobulins showed marked immunologic changes in the course of the syndrome. Antistaphylococcal treatment, without corticotherapy led to clinical recovery.

Reactivation of varicella zoster virus following trigeminal schwannoma resection.

Varicella zoster is found exclusively in humans. Infected people with this virus result in chickenpox followed by dormant virus within neural ganglia. This dormant virus, once activated, may affect any ganglia or nerves of the body but most commonly involves the thoracic, cervical and trigeminal nerves in decreasing order of frequency. We review three such cases in which manipulation of the trigeminal ganglion resulted in reactivation of varicella at homologous operative sites. Each patient underwent surgeries in which the trigeminal ganglion was manipulated for the resection of trigeminal sch…

Simultaneous infection of measles and varicella-zoster virus in a child in India.

Simultaneous occurrence of measles and chickenpox in a single individual is a rare event despite the fact that each of these infections alone is very common. The clinical presentation and molecular characterization of a dual infection caused by measles and Varicella-Zoster virus (VZV) in a 3-year female child is reported for the first time from India. The child presented with high fever, cough, cervical lymphadenopathy, and maculopapular rash followed by vesicular skin rash. The child was not immunized against measles and chickenpox. The viral nucleic acids extracted from the clinical specimen…

Pox in the docks: varicella outbreak in an Australian prison system.

OBJECTIVES: 1. Describe an outbreak of varicella in a prison system. 2. Highlight the risks of disease transmission within the prison environment. 3. Promote infection control guidelines for high-risk sub-groups within the prison system, including the application of quarantine. SETTING: Four prisons, one prison hospital, the prison transport system, one courthouse. MAIN OUTCOME MEASURES: Number of cases of varicella infection; reported varicella immunity status of cases and contacts; immunity status of known HIV antibody positive inmates. RESULTS: Five cases of chickenpox were identified. T…

Use of immunization as strategy for outbreak control of varicella zoster in an institutional setting.

BACKGROUND: Outbreaks of varicella gets reported often in India. However, outbreak in health care providers living in closed institutional setting and role of vaccination as post exposure prophylaxis for control of outbreak has not been studied extensively. This paper presents epidemiological investigation and control strategy undertaken in such scenario. METHODS: This is an epidemiological investigation of chickenpox in nursing students which highlights role of early identification and appropriate control strategy to prevent explosive outbreak in high risk vulnerable population. Vaccination …

Comments on vaccines, August 1987.

Because of latency and infectious recurrences, eradication of herpes simplex and herpes zoster from the world by vaccines is likely to be much more difficult to accomplish than eradication of smallpox. For some time we may have to settle for control of these diseases rather than their eradication. The live, attenuated varicella vaccine protects immunocompromised and normal persons against clinical chickenpox but it does not completely prevent subsequent infection with natural chickenpox virus or latency. With herpes simplex vaccines we may have to be satisfied with amelioration or control of c…

Кратковременная и низкодозированная внутривенная ацикловирусная терапия у зостерных инфекций варицеллы и злокачественных заболеваний у детей, проходящих комбинированную химиотерапию.

Сообщается о последствиях низкодозированной и коротковременной ацикловирусной терапии для 14 детей с злокачественными заболеваниями в возрасте от 4 до 18 лет, у которых во время агрессивной химиотерапии появились вирусные инфекции варицелла-зостера. У десяти из них была ветрянка и 4 герпеса. Ацикловир 5 мг/кг подавался IV каждые 12 часов на 9 пациентов и каждые 8 часов на 5 пациентов в среднем за 4 дня. Мы возобновили первичную терапию, когда повреждения пациентов высохли и стали корчиться и новые повреждения не появились снова. Период начала ацикловирусной терапии для возобновления онкологиче

Совпадение в аннотации оригинала
The effects of low-dose and short-time acyclovir therapy in 14 children with malignant disease of ages 4-18 years who had developed varicella zoster virus infections while receiving aggressive chemo-/+radiotherapy are reported. Ten of them had chickenpox and 4 herpes zoster. Acyclovir 5 mg/kg was infused IV every 12 h in 9 patients and every 8 h in 5 patient…

[Ibuprofen in childhood: evidence-based review of efficacy and safety].

Ibuprofen is the non-steroidal anti-inflammatory drug most prescribed for the treatment of fever and moderate pain in childhood. Its analges … es. These data suggest there is an increased risk of invasive group A streptococcal infection after chickenpox and of acute renal failure in case of hypovolemia after a treatment by ibuprofen. Gastroduodenal and hemorrhagic adverse events could also happen, but the causality with ibuprofen is not demonstrated. Therefore, ibuprofen is not recommended for the …

Shingles in Alberta: before and after publicly funded varicella vaccination.

PURPOSE: A universal publicly funded chickenpox vaccination program was implemented in Alberta in 2002. We examine the epidemiology of medically attended shingles in Alberta from 1994 to 2010. METHODS: Incident shingles cases (earliest health service utilizations for ICD-9 053 or ICD-10-CA B02) and their co-morbid conditions for the 12 months prior to shingles diagnosis were identified from the records of Alberta's universal, publicly funded health-care insurance system for 1994-2010. Shingles diagnostic codes at least 180 days after the first were classified as recurrent episodes. Denominato…

Teenagers' understandings of and attitudes towards vaccines and vaccine-preventable diseases: a qualitative study.

BACKGROUND: To examine immunisation information needs of teenagers we explored understandings of vaccination and vaccine-preventable diseases, attitudes towards immunisation and experiences of immunisation. Diseases discussed included nine for which vaccines are currently offered in the UK (human papillomavirus, meningitis, tetanus, diphtheria, polio, whooping cough, measles, mumps and rubella), and two not currently included in the routine UK schedule (hepatitis B and chickenpox). METHODS: Twelve focus groups conducted between November 2010 and March 2011 with 59 teenagers (29 girls and 30 b…

Evaluation of anti-varicella antibody in young women before their marriage: A sero-epidemiologic study in Iran.

BACKGROUND: Chickenpox during pregnancy can cause severe complications in both the mother and her baby. However, no complications will occur in a mother with proper immunity. Therefore, physicians and health systems can make better decisions when they know the immunologic status of the women in a community. OBJECTIVES: We conducted this study to clarify the Varicella zoster virus (VZV) immune status of engaged women in Iran. STUDY DESIGN: This cross-sectional descriptive study was carried out on 334 young women who intended to marry between 2006 and 2008. The subjects' VZV-immunoglobulin G (…

[Herpes zoster in a 12-month-old girl subsequent to intrauterine exposure to the varicella-zoster virus].

A few cases have been recorded in which zoster was presumably due to reactivation of V-Z virus acquired during the intrauterine life. In our patient, a 12-month-old infant, the mother had chickenpox during her seventh month of pregnancy.

Morphometric Analysis of the Acetabular Anterior Column for Retrograde Screw Fixation: A Comparative CT Study.

OBJECTIVE: To describe the clinical manifestations laboratory findings and frequency of complications in adult chickenpox patients admitted in the hospital. METHODS: This was a hospital based descriptive study, conducted at the Infectious Diseases Unit, Rashid Hospital Dubai, UAE, from March 2005 to February 2008. The study was designed to include demographics (age, sex, nationality); clinical information, radiological and biochemical changes observed in each patient and data was entered into the proforma separately. Full blood count, urea, electrolytes and blood sugar were done for all the p…

[Prophylaxis in severe congenital neonatal varicella. Apropos of two cases].

We present two cases of neonatal varicella in newborn twins, who had serious complications in spite of being given human anti-chickenpox immuneglobulin (zoster immuneglobulin ZIG) prophylaxis. We comment on current criteria of the prophylaxis in newborns with risk of severe neonatal varicella.