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On the occurrence of mirror modes at Mercury and their comparison with magnetic holes and ion cyclotron waves.

In the context of this review, civil unrest is defined as disharmony, expressive dissatisfaction and/or disagreement between members of a community, which leads to a situation of competitive aggression that may find expression as disruption of organisation, conflicts, damage to property and injuries. Such a breakdown of harmonious relationships, which may result in property damage and human injuries that may be threatening to life, varies in magnitude from participation of a very few individuals up to the involvement of large crowds of people, which may evolve into a full-scale riot. It is the

A nationwide survey of knowledge of and compliance with cancer pain management guidelines by korean physicians.

PurposeAlthough cancer pain is prevalent, under-treatment still remains a problem. Knowledge of and compliance with guidelines for management of cancer pain were analyzed for exploration of physician-related barriers to cancer pain management. In addition, physicians' knowledge and its correlation with cancer pain control were audited.Materials and methodsFrom July 8 to December 2, 2010, a nationwide survey of house staff enquired about their knowledge of cancer pain control guidelines, and the medical records of patients under their care were analyzed.ResultsIn total, 180 physicians participa

Do health service waiting areas contribute to the health literacy of consumers? A scoping review.

Health service waiting areas commonly provide health information, resources and supports for consumers; however, the effect on health literacy and related outcomes remains unclear. This scoping review of the literature aimed to explore the use of waiting areas as a place to contribute to the health literacy and related outcomes of consumers attending health appointments. Articles were included if they focussed on health literacy or health literacy responsiveness (concept) in outpatient or primary care health service waiting areas (context) for adult consumers (population) and were published af

Japanese POEMS syndrome with Thalidomide (J-POST) Trial: study protocol for a phase II/III multicentre, randomised, double-blind, placebo-controlled trial.

IntroductionPolyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS) syndrome is a fatal systemic disorder associated with plasma cell dyscrasia and the overproduction of the vascular endothelial growth factor (VEGF). Recently, the prognosis of POEMS was substantially improved by introduction of therapeutic intervention for myeloma. However, no randomised clinical trial has been performed because of the rarity and severity of the disease.Methods and analysisThe Japanese POEMS syndrome with Thalidomide (J-POST) Trial is a phase II/III multicentre, double-blinded, randomi

Implementing patient-centred outcome measures in palliative care clinical practice. An updated systematic review of facilitators and barriers.

BackgroundPatient-centred outcome measures (PCOMs), when well implemented, are powerful tools facilitating patient, family and clinical communication to better respond to patient needs. Their routine use in palliative care practice still faces challenges.ObjectiveTo update a systematic review of PCOMs implementation, reviewing and synthesising new evidence on facilitators, barriers, lessons learned, measures used, models of implementation, costs, implementation outcomes, and consequences in clinical practice.MethodsWe searched eight information sources supplemented by hand-searching and citati

Расовая неравноправие, множественный склероз и внедрение нового лечения алгоритма на уровне системы здравоохранения.

СПРАВОЧНАЯ ИНФОРМАЦИЯ И ЗАДАЧИ: Достижения в области множественного склероза (МС) не привели к справедливому улучшению лечения НР или результатов среди миниатюризированных людей. Наша цель заключалась в том, чтобы определить, осуществляются ли меры системы здравоохранения, направленные на расширение использования высокоэффективных методов лечения, на справедливой основе и привели ли они к аналогичным улучшениям в показателях НР среди расовых и этнических групп.МЕТОДЫ: Мы разработали и внедрили алгоритм лечения MS, который увязывает риск инвалидности человека с надлежащим образом эффективными м

Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes.

BACKGROUND: There is a large body of evidence evaluating quality improvement (QI) programmes to improve care for adults living with diabetes. These programmes are often comprised of multiple QI strategies, which may be implemented in various combinations. Decision-makers planning to implement or evaluate a new QI programme, or both, need reliable evidence on the relative effectiveness of different QI strategies (individually and in combination) for different patient populations. OBJECTIVES: To update existing systematic reviews of diabetes QI programmes and apply novel meta-analytical techniq

Mortality rate after open Roux-in-Y gastric bypass: a 10-year follow-up.

The prevalence of obesity has increased to epidemic status worldwide. Thousands of morbidly obese individuals undergo bariatric surgery for sustained weight loss; however, mid- and long-term outcomes of this surgery are still uncertain. Our objective was to estimate the 10-year mortality rate, and determine risk factors associated with death in young morbidly obese adults who underwent bariatric surgery. All patients who underwent open Roux-in-Y gastric bypass surgery between 2001 and 2010, covered by an insurance company, were analyzed to determine possible associations between risk factors p

SUBJECT INDEX Volume 125 (JANUARY–JUNE, 2004)

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Свойства измерений и их применение WHODAS 2.0 в многоразовом склерозе: систематический обзор.

Фон/задачи: Множественный склероз (МС) влияет на моторное, когнитивное, психологическое и социальное функционирование, которое не в полной мере фиксируется на основе нарушений. В ходе этого систематического обзора была проведена оценка свойств измерений и их применения в соответствии с графиком Всемирной организации здравоохранения по оценке инвалидности (WHODAS) 2.0 для взрослых с МЗ в исследовательских и клинических контекстах. Методы: с момента создания библиотеки Пубмед/МЕДЛИН, Эмбазы, Скопуса, Сети науки и Кокрана до 25 мая 2026 года был проведен обыск. В ходе соответствующих экспертных и

Telehealth exercise to Improve Physical function and frailty in patients with multiple myeloma treated with autologous hematopoietic Stem cell transplantation (TIPS): protocol of a randomized controlled trial.

BACKGROUND: Advances in autologous hematopoietic stem cell transplantation (HSCT) and supportive care have led to marked improvements in survival for patients with multiple myeloma. Despite these improvements, patients with multiple myeloma remain at high risk of physical dysfunction and frailty due to HSCT and its associated exposures. Although traditional supervised exercise programs can improve frailty in cancer patients and survivors, rehabilitation facilities are typically far from a patient's residence, are offered on fixed days/hours, contain uniform activities for everyone, and carry a

Mortality Audit of Cancer Patients in the Department of Medical Oncology at a Tertiary Cancer Care Centre in South India.

Considerable advances in the diagnosis and treatment of cancer have made a huge impact on morbidity and mortality from neoplastic diseases. However, cancer remains the leading cause of death across the world. This is a retrospective study carried out at a tertiary cancer care centre (Kidwai Memorial Institute of Oncology, Bangalore) in South India. Case records of all cancer patients who died while receiving inpatient treatment between January 2022 and December 2022 under the Department of Medical Oncology were reviewed and studied. There was a total of 240 deaths. Out of these, the majority o

Антибиотическое управление в случае предполагаемой нейтральной лихорадки (испытание ASTERIC): мультицентр, тип 1 гибридный протокол проведения экспериментальных исследований по вопросам эффективности, ступенчатый, выборочный и контролируемый.

ВВЕДЕНИЕ: Нейтропеническая лихорадка (НФ) имеет общий коэффициент смертности: 3-18%. Международные руководящие принципы рекомендуют всем пациентам, имеющим NF, получать антибиотики сверхширокого спектра (UBSA) в пределах 1 час регистрации аварийного отделения (ЭД). Тем не менее, 70% пациентов, поступающих в больницу с подозрением в наличии NF (SNF), не могут получить доступ к абсолютному числу нейтрофильов (ANC) в пределах 1 час, не имеет NF и не требует UBSA. В скорой и госпитализированных пациентах, имеющих SNF, мы предполагаем, что протокол ASTERIC эффективно и безопасно сокращает использов

Translation research: 'Back on Track', a multiprofessional rehabilitation service for cancer-related fatigue.

OBJECTIVES: To assess the effectiveness and acceptability of an individually tailored rehabilitation intervention for patients with cancer-related fatigue (CRF). METHODS: Eighteen individuals, (16 female, two male, aged 40-83 years), who self-reported CRF (above four on a 10-point Likert scale) took part in an 8 week physical activity intervention weekly review and optional gym-based support. Fifteen participants had a primary diagnosis of breast cancer and along with the other participants had multiple myeloma, colorectal or prostate cancer. All participants took part in a goal-oriented walk

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… Clinical audit in palliative care. Oxford: Radcliffe Medical Press, 1993:61–77. 14. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories.. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med 2002;166:111–17. 15. …

Phenotypes and rates of cancer-relevant symptoms and tests in the year before cancer diagnosis in UK Biobank and CPRD Gold.

Early diagnosis of cancer relies on accurate assessment of cancer risk in patients presenting with symptoms, when screening is not appropriate. But recorded symptoms in cancer patients pre-diagnosis may vary between different sources of electronic health records (EHRs), either genuinely or due to differential completeness of symptom recording. To assess possible differences, we analysed primary care EHRs in the year pre-diagnosis of cancer in UK Biobank and Clinical Practice Research Datalink (CPRD) populations linked to cancer registry data. We developed harmonised phenotypes in Read v2 and C

Clinical outcomes of bortezomib-based therapy in myeloma.

Bortezomib, a first generation proteasome inhibitor, is used in both newly diagnosed and relapsed myeloma settings. Considerable differences exist in the usage of bortezomib therapy in the clinical practice setting in comparison to clinical trial setting as well manufacturer's recommendations. These differences include route of administration (intravenous (iv) vs. subcutaneous (sc)), frequency from twice to once weekly, choice of alkylating agent used in combination with bortezomib (melphalan or cyclophosphamide), and choice of glucocorticoids (dexamethasone or prednisolone). We reviewed data

Rasburicase vs. allopurinol: mortality in hematological malignancies post anti-hyperuricemic therapy - real-world study.

PURPOSE: This retrospective, real-world (RW) study utilizing propensity score matching investigated tumor lysis syndrome (TLS)-related mortalities following anti-hyperuricemic (HU) monotherapy (allopurinol vs. rasburicase) in hematological malignancies. The study aim was to determine if a significant difference exists in the proportion of TLS-associated mortalities in hematological malignancy patients who received either rasburicase or allopurinol. METHODS: Following random selection of patient cases of rasburicase or allopurinol monotherapy, 141 in each group were PS-matched for TLS risk usi

Real-world assessment of the clinical impact of symptomatic infection with severe acute respiratory syndrome coronavirus (COVID-19 disease) in patients with multiple myeloma receiving systemic anti-cancer therapy.

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… We conducted a fully‐anonymised prospective clinical audit where only MM patients with documented symptomatic COVID‐19, whether managed in the inpatient or outpatient setting, were reported. …

Assessment of Psychiatric Disorders in Consultation-Liaison Setting.

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Design and development of the Australian and New Zealand (ANZ) myeloma and related diseases registry.

BACKGROUND: Plasma cell dyscrasias (PCD) are a spectrum of disorders resulting from the clonal expansion of plasma cells, ranging from the pre-malignant condition monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM). MM generates a significant burden of disease on the community and it is predicted that it will increase in both incidence and prevalence owing to an ageing population and longer survival secondary to new therapeutic options. Robust and comprehensive clinical data are currently lacking but are required to define current diagnostic, investigational and