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Pre- and post-diagnosis physical activity, television viewing, and mortality among hematologic cancer survivors.

PurposeThe associations of physical activity and television (TV) viewing with mortality risk among individuals with hematologic malignancies remain unclear.MethodsWe examined the relations of physical activity and TV viewing time before and after diagnosis with mortality among 5182 U.S. adults aged 50-71 years from the NIH-AARP Diet and Health Study cohort who survived a first primary hematologic cancer between 1995-1996 and 2011.ResultsFor the pre- and post-diagnosis analyses, we confirmed 2606 and 613 deaths respectively. In multivariable-adjusted Cox proportional hazard regression models, c

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… The Florida cancer incidence data were collected by the Florida Cancer Data System under contract with the Florida Department of Health, Tallahassee, Florida; the views expressed herein are solely those of the authors and do not necessarily reflect those of the Florida Cancer Data System or the Florida …

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.

BACKGROUND: The majority of hypertensive individuals require combination antihypertensive therapy to achieve adequate blood pressure (BP) control. This study aimed to identify genetic variants associated with uncontrolled BP on combination therapy with a thiazide diuretic and a β-blocker. METHODS AND RESULTS: A genome-wide association study of uncontrolled BP on combination therapy was conducted among 314 white participants of the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) trial. Multivariable logistic regression analysis was used. Genetic variants meeting a suggestive le

:: воздействие программы < < Передовая практика > > на пациентов с повторной/отправленной миеломой, принимающих Селинксор.

Передовая практика (БП) в области лечения раковых заболеваний включает в себя многоплановый подход, включающий индивидуальные планы лечения, основанную на фактических данных медицину, оптимальное использование вспомогательных услуг и просвещение пациентов. Мы изучили последствия программы BP для пациентов с реанимацией/отменой множественных миелом (RRMM), получающих селинксор. Особенности программы BP, специфичные для селинксора, инициировали селинксор при дозах ≤80 gg раз в неделю и переднее использование стандартизованных антиметиков. К числу конечных точек исследования относятся время, необ

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… Florida Cancer Specialists and Research Institute (FCS) implemented a BP program on 1 March 2022. The BP program was tailored to address the drug delivery challenges associated with individual anticancer drugs, such as selinexor. … L.N.G., A.W., T.H., M.F., D.W., P.C., N.K. and S.P. are all employees of the Florida Cancer Specialists and Research Institute, Tampa, FL 33609, USA. There are no other conflicts of interest to declare. References 1. …

Selected Abstracts from the 12th Annual Meeting of the Clinical Immunology Society: 2021 Virtual Annual Meeting: Immune Deficiency and Dysregulation North American Conference.

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… relatives: the importance of pursuing a genetic diagnosis Maria Chitty Lopez , MD 1 , Farnaz Tabatabaian, MD 2 , Hana Niebur, MD 3 , Erinn Kellner, MD 4 , Gulbu Uzel, MD 5 , Jennifer Leiding, MD 6 1 Physician Fellow/Division of Allergy and Immunology, Department of Pediatrics, University of South Florida … , Tampa, FL, USA 2 Assistant Professor/Division of Allergy & Immunology, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Fla 3 Assistant Professor/Division of Allergy and Immunology, Department of Pediatrics, University of Nebraska, Omaha, NE, USA …

First Report of Korean Cyst Nematode, Heterodera koreana, Parasitic on Bamboo, Phyllostachys nigra, from Iran.

Bamboo is grown sporadically in the north of Iran and is confined to very limited areas. The history of growing bamboo was to some extent si … an. So far the Korean cyst nematode was reported from South Korea, Thailand, and the United States, Florida (from nurseries); this study includes the distribution of this cyst-forming nematode in Iran and expands the information of the occurrence of H. koreana for the world.

Whole-body MRI for a patient with progressive multiple myeloma.

Multiple Myeloma represents a plasma cell disorder that can result in hallmark bony destructive change in addition to other signs of myelomatous disease. Imaging often helps in establishing the diagnosis and staging the patient. There are several different imaging modalities that can provide different levels of insight into the disease extent. We report a unique case of multiple myeloma where the progressive nature of the patient's disease highlights the strengths and limitations of the different imaging approaches. Whole-body MRI represents a noncontrast imaging technique that directly images

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… Contributor Information Jonathan E Henning, University of South Florida Morsani College of Medicine, Tampa, FL 33602, United States. Taiga Nishihori, Department of Blood & Marrow Transplant and Cellular Immunotherapy, H. … Davis Kuruvilla, University of South Florida Morsani College of Medicine, Tampa, FL 33602, United States. Sebastian Feuerlein, Department of Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States. …

Perspective: Does personalized medicine hold the future for medicine?

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… Genomas Expands Personalized Medicine Business with Clinical Laboratory Licenses in New York, Florida, California. 2013. [Last accessed on 2013 Aug 10]. … Available from: http://www.prnewswire.com/news-releases/genomas-expands-personalized-medicine-business-with-clinicallaboratory-licenses-in-new-york-florida-california-194824371.html . 18. West D. Enabling Personalized Medicine through Health Information Technology. 2011. …

Sex differences in physical activity, psychosocial determinants, and symptom outcomes in knee osteoarthritis: a cross-sectional analysis of a Hispanic/Latino-predominant cohort.

Knee osteoarthritis (KOA) is a chronic disease that often leads to persistent pain, functional limitations, and diminished quality of life. Physical activity can be an effective countermeasure but its adherence typically relies on behavioral determinants. Currently, there is limited work investigating how clinical symptoms among patients with KOA affect behavioral determinants, and there is a need for further insight into why females engage in less physical activity. The purpose of this study was to investigate these questions in a sample of patients with KOA. Patients (n = 736; mean age 56.4

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… A total of 736 participants were recruited at a tertiary medical center in Miami-Dade County, Florida. Eligible patients were those attending their first clinic visit, aged 18 years or older, with valid insurance, and presenting with knee pain and/or stiffness. … Additionally, our sample is drawn from a predominantly Hispanic/Latino population in South Florida, a demographic group underrepresented in prior publications on KOA psychosocial research [ 35 ]. …

Use of carfilzomib in second-line therapy and beyond for relapsed multiple myeloma.

The development of proteasome inhibitors has been a major advance in therapy of multiple myeloma, accounting, in part, for the significant increase in the survival of patients diagnosed with this disease. Bortezomib was the first proteasome inhibitor to be approved for the therapy of multiple myeloma. Carfilzomib is a second-generation proteasome inhibitor with irreversible binding to proteasome and less off-target toxicity. The drug has been approved for use in relapsed/refractory multiple myeloma. In this article, we review the use of carfilzomib as second-line therapy in multiple myeloma. W

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… American Society of Hematology Annual Meeting 2015; Orlando, Florida. Abstract 1840. 42. Berdeja JG, Hart LL, Mace JR, et al. Phase I/II study of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma. … American Society of Hematology Annual Meeting 2015; Orlando, Florida. Abstract. 728 57. Richardson PG, Siegel DS, Vij R, et al. Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study. …

Selected Abstracts from the 13th Annual Meeting of the Clinical Immunology Society: 2022 Annual Meeting: Immune Deficiency and Dysregulation North American Conference

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… of Medicine, University of South Florida, Tampa, FL; Johns Hopkins All Children's Hospital, St Petersburg, FL, USA 3 University of South Florida and Johns Hopkins All Children's Hospital, St. … Petersburg, FL, USA 4 Morsani College of Medicine, University of South Florida, Tampa, FL, USA; Johns Hopkins All Children's Hospital, St Petersburg, FL, USA 5 Drexel University College of Medicine 6 University of South Florida and Johns Hopkins All Children's Hospital, St. …

2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference.

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Disparities in survival of hematologic malignancies in the context of social determinants of health: a systematic review.

Social determinants of health (SDHs) have been reported as relevant factors responsible for health inequity. We sought to assess clinical data from observational studies conducted in the United States evaluating the impact of SDHs on the outcomes of patients with hematologic malignancies. Thus, we performed a systematic review in 6 databases on 1 September 2021, in which paired reviewers independently screened studies and included data from 41 studies. We assessed the risk of bias using the Joanna Briggs Institute appraisal tools and analyzed the data using a descriptive synthesis. The most co

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… State studies assessed cancer registries: 4 studies from California (11.1%), 1 from Florida (2.2%), 1 from New York (2.2%), 1 from North Carolina (2.2%), and 1 from Virginia (2.2%). Institutional studies retrieved data from the patients’ medical records. … Cancer Data System; FL, Florida; HL, Hodgkin lymphoma; HR, hazard ratio; MDS, myelodysplastic syndromes; MM, multiple myeloma; multi, multivariate analysis; N, sample size; NC, North Carolina; NC CCR, North Carolina Central Cancer Registry; NCDB, National Cancer Database; NHL, non-Hodgkin lymphoma; …

Abstracts of the 3rd International Conference on Cancer Cachexia, September 23–25, 2016 in Washington, DC, USA

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… Lee Moffitt Cancer Center, Tampa, Florida, USA; 2 University of Alberta Canada, Edmonton, Alberta, Canada Recent findings suggest that computed‐tomography (CT)–defined features of body composition (ie skeletal muscle, fat amount and distribution) predict for cancer‐associated survival. … George 4 and Lucio Gordan 5 1 College of Nursing, University of Florida; 2 College of Pharmacy, University of Florida; 3 Sunshine Integrative Health; 4 Hematology/Oncology, College of Medicine, University of Florida; 5 Florida Cancer Specialists & Research Institute, Gainesville, FL, USA Significance …

Gene Therapy with CRISPR/Cas9 Coming to Age for HIV Cure.

The huge success of current antiretroviral therapy is mediated by a triple effect: (i) Halting progression to AIDS in infected persons; (ii) … d in the development of Cas9/gRNA nanoparticle formulations. To overcome these problems, a group in Florida recently developed human transgenic cells that may be used for gene-editing studies and as platform for high-throughput screen of HIV provirus disrupters (Huang et al. Sci Rep 2017;7:5955). Of note, Cas9 protein instead of a Cas9 plasmid was used. C …

Viewing the US presidential electoral map through the lens of public health.

Health, disease, and mortality vary greatly at the county level, and there are strong geographical trends of disease in the United States. Healthcare is and has been a top priority for voters in the U.S., and an important political issue. Consequently, it is important to determine what relationship voting patterns have with health, disease, and mortality, as doing so may help guide appropriate policy. We performed a comprehensive analysis of the relationship between voting patterns and over 150 different public health and wellbeing variables at the county level, comparing all states, including

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… "Battleground states” are the tightly contested states of the 2016 Presidential election: Nevada, Colorado, Virginia, Florida, Michigan, Minnesota, Wisconsin, Iowa, New Hampshire, Ohio, and Pennsylvania. … The battleground states are: Nevada, Colorado, Virginia, Florida, Michigan, Minnesota, Wisconsin, Iowa, New Hampshire, Ohio, and Pennsylvania. The flipped states are: Michigan, Pennsylvania, Wisconsin and Maine. …

2019 ASCO Annual Meeting Highlights for the Advanced Practitioner: Issues in Oncology.

Several abstracts presented at the ASCO Annual Meeting reflected the meeting theme of providing high-quality care to every patient. Following coverage by The ASCO Post, Editor-in-Chief to JADPRO, Pamela Hallquist Viale, RN, MS, CNS, ANP, comments on abstracts revealing disparities afflicting both providers and patients in the cancer care community, as well as initiatives designed to combat them.

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… At a press conference, ASCO expert Merry-Jennifer Markham, MD, Associate Director for Medical Affairs at the University of Florida Health Cancer Center, Gainesville, Florida, weighed in on this study. “Ovarian cancer is a deadly disease. …

Fertility preservation trends, perspectives, and reflections in gender diverse adults across the life course.

STUDY QUESTION: What is the fertility preservation (FP) utilization rate among transgender and gender diverse (TGD) patients at the Transgen … ess coordination for Lesbian, Gay, Bisexual, and Transgender (LGBT) teens and young adults in North Florida. Individuals were invited to participate in a qualitative interview exploring their cumulative healthcare experiences accessing gender-affirming care. Interviews were conducted from January 2023 to June 2023. Interviews examined participants' percep …