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Digital health interventions for promoting physical activity among adolescents: a systematic review.

BACKGROUND: The issue of insufficient physical activity in adolescents (defined by the World Health Organization as those aged 10-19 years) … s. (2) relational design, features like team challenges, empathetic AI characters, and customizable avatars can boost confidence by 50% and motivation by 120%; and (3) contextual relevance, data indicates that moderate to vigorous physical activity (MVPA) peaks between 5 and 8 p.m., highlighting the critical difference between screen time (which can hind …

Меры по оказанию помощи в случае хронических заболеваний, основанные на группировании: систематический обзор случайных контролируемых испытаний.

Растущее глобальное бремя хронических заболеваний требует новых и интерактивных и устойчивых мер. Гамификация стала новаторской стратегией, направленной на более активное вовлечение пациентов в лечение хронических заболеваний и их самостоятельное лечение. Хотя gamification широко используется в сфере здравоохранения, анализ данных о ее эффективности в различных клинических условиях остается непоследовательным. three основные базы данных: EBSCOhost, PubMed и Scopus вместе с two поисковые системы, включая Google Scientific and Sage Journal, без ограничений по годам, после PRISMA 2020 и методолог

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… . | 10/13 Loerzel et al 2020 25 | RCT | USA | Older adults ≥60 years with cancer (n=80) | Community cancer center (chemo setting) | eSSET-CINV serious game (iPad-based): avatar-based decision-making on CINV prevention and management | The intervention group engaged more in preventive behaviors, while … The gamification components used are episodic narratives, avatars, points and badge systems, leaderboards, time-based challenges, direct feedback, and material rewards. …

Неучтенная роль экгасомов в когнитивно-моторной нейрореабилитации: систематический обзор.

Эксгармии — это новые инструменты когнитивно-моторной нейрореабилитации, но их воздействие на взрослых с неврологическими условиями еще недостаточно изучено. В рамках этого систематического обзора были изучены исследования, полученные из PubMed, Scopus, Embase и Web of Science, с оценкой воздействия экзотомов на двигательные и когнитивные результаты. К числу приемлемых исследований относятся случайные контролируемые испытания (РСТ), не связанные с РСТС и экспериментальные проекты. Протокол был зарегистрирован на сайте ПРОСПЕРО (CRD420250655053) и составлен в соответствии с руководящими принцип

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… Leveraging affordances to study the impact of avatar/interaction coherence on embodiment and plausibility in virtual reality. IEEE Trans. Vis. Comput. Graph . 31 , 2611–2621 (2025). 46. Do, T. D., Benjamin, J., Protko, C. I. & McMahan, R. P. … Cultural reflections in virtual reality: the effects of user ethnicity in Avatar matching experiences on sense of embodiment. IEEE Trans. Vis. Comput. Graph. 30 , 7408–7418 (2024). 47. Impellizzeri, F. et al. …

Virtual Reality-Based Exercise Rehabilitation in Cancer-Related Dysfunctions: Scoping Review.

BackgroundVirtual reality-based exercise rehabilitation (VRER) is a promising intervention for patients with cancer-related dysfunctions (CRDs). However, studies focusing on VRER for CRDs are lacking, and the results are inconsistent.ObjectiveWe aimed to review the application of VRER in patients with CRDs.MethodsThis scoping review was conducted following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist framework. Publications were included from the time of database establishment to October 14, 2023. The databases were

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… ), “Card Island,” “Remember that Card” (match card), “Musical Drums” (strike notes using drum stick avatars), “Xylophone” game (repeat notes using mallet avatars), “Pick & Place” (grasp and move balls), “Arm Slalom” (rotate the shoulder to guide a skier avatar through a downhill slalom), “Avalanche” … (control a pick axe and a shovel avatar to break and clear ice walls), and “Treasure Hunt” game (control shovel avatars to find buried treasure) | 20 to 50 minutes per session, 2 sessions per week for 8 weeks Jin et al [ 46 ], 2018 | Breath and raise the leg, ball throw, hair comb, pendulum, shoulder …

Экспериментальное технико-экономическое обоснование исследования виртуальной оценки гейт на основе реальности с орехами у людей с множественным склерозом: исследовательский протокол.

Множественный склероз (МС) часто приводит к значительным нарушениям в походах и мобильности. Несмотря на то, что пешие брекеты обычно предписываются, их эффективность в реальном мире ограничивается недостаточной адаптацией. Традиционные клинические оценки основываются на субъективных масштабах и могут не в полной мере отражать проблемы повседневной жизни. Неизмеримая виртуальная реальность (VR) и износимые сенсоры предлагают перспективные решения для экологического мониторинга, однако их комбинированное использование по-прежнему не является приемлемым для ортопедической поддержки в MS. В рамка

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… Lower limb movements are tracked using the Meta Quest 3 embedded camera‐based tracking system, which allows real‐time avatar representation and enhanced visual feedback during gait. … In VR conditions, the Meta Quest 3 cameras will be used to track participants' body movements and replicate them on a virtual avatar. All trials will also be video recorded with the two GoPro cameras for markerless motion analysis. …

Оценка функции верхнего лимфа с использованием технологий виртуальной реальности для взрослых с неврологическими расстройствами: систематический обзор.

Справочная информация: Виртуальная реальность (ВП) все чаще изучается в качестве инструмента для оценки состояния верхних конечностей (УЛ) у взрослых с неврологическими расстройствами. Этот обзор обобщает имеющиеся данные оценок UL на основе VR путем анализа их психометрических свойств и потенциальной роли в клинических и исследовательских условиях. Методы: Этот систематический обзор проводился в соответствии с руководящими принципами представления отчетности о систематических обзорах инструментов оценки результатов (PRRISMA-COSMIN) и был в перспективе зарегистрирован в ПРОСПЕРО. Добыча данных

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… Compensatory strategies, such as trunk movement, were minimized by restricting avatar motion to the affected limb, ensuring that recorded performance reflected true motor capacity [ 33 ]. … Combined with Microsoft Kinect ® data and kinematic algorithms, the system enabled real-time estimation of UL joint movements and reconstruction of the patient’s avatar. …

Exploring the characteristics of conversational agents in chronic disease management interventions: A scoping review.

ObjectiveWith the increasing global burden of chronic diseases, there is the potential for conversational agents (CAs) to assist people in actively managing their conditions. This paper reviews different types of CAs used for chronic condition management, delving into their characteristics and the chosen study designs. This paper also discusses the potential of these CAs to enhance the health and well-being of people with chronic conditions.MethodsA search was performed in February 2023 on PubMed, ACM Digital Library, Scopus, and IEEE Xplore. Studies were included if they focused on chronic di

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… male 67% | White 50% and AA 50% | 14 days | One | Qualitative, quantitative | Acceptability, feasibility 35 | Heart failure for 7 years on average | 57 | 55 (>18) | Gender: female 35%, male 61%, missing 4% | Black 61% | 90 days | Nonrandomized Two: smart speaker and visually animated and voice-enabled avatar … interventions: responses from chatbot versus responses from physicians, 57 interaction with a chatbot concerning pain management versus reception motivational messages unrelated to chronic pain, 49 bibliotherapy versus chatbot interaction, 54 and smart speaker versus visually animated and voice-enabled avatar …

Виртуальная реальность в области аутизма и физической терапии: метааналитический обзор клинических результатов и терапевтической эффективности.

Технология Virtual Reality (VR) стала трансформативной терапевтической инновацией в сфере здравоохранения, обеспечивая императивность three- многомерная, многочувствительная среда, способствующая практическому обучению, реабилитации и взаимодействию. Хотя результаты многочисленных исследований свидетельствуют о его преимуществах, эмпирические исследования в области основанных на VR методов лечения расстройства аутистического спектра (ASD) и физической терапии (PT) по-прежнему ограничиваются методологическими несоответствиями, небольшими размерами выборки и изменяющимися схемами вмешательства.

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… Body dissatisfaction directs avatar perception: embodiment and selective visual attention in body mass-modified self-avatars. Cyberpsychol Behav Soc Netw. (2023) 26(11):850–60. 10.1089/cyber.2022.0385 26. Kocur M, Henze N, Schwind V, Habler F, Wolff C, Woźniak PW. … Physiological and perceptual responses to athletic avatars while cycling in virtual reality. In: Proceedings of the 2021 CHI Conference on Human Factors in Computing Systems (CHI '21). New York, NY: Association for Computing Machinery; (2021). p. 519, 18. 10.1145/3411764.3445160 27. …

Cancer during a pandemic: A psychosocial telehealth intervention for young adults.

The SARS-II COVID-19 pandemic has posed pronounced global health threats and prompted assorted transformations in societal engagement and clinical service delivery. For cancer survivors, many of whom are immune-compromised, these pandemic-related health threats pose greater challenges, warranting extra precautions within everyday living. Young adult (YA) cancer survivors already confront many unique physical and emotional challenges specific to their demographic. Already comfortable with assorted technologies, the pandemic presented an opportunity to provide telehealth intervention that target

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… | Personal and medical check-ins, avatars as metaphors, polar bear and open mind mindfulness practices 4 | Self-Observation, Legacy & Values: “How can acting on life serve my values?” …

Унификация одиссеи: искусственный интеллект для диагностирования и лечения редких заболеваний.

Подытожить текущие проблемы в диагностике и лечении редких заболеваний (РД), осветить последние достижения в области искусственного интеллекта (АИ) для РД и предложить модель будущего состояния лечения пациентов РД. Многодисциплинарный экспертный обзор с кратким изложением современных практических задач и мер по ограничению ставок в области РД-клиентов с учетом ключевых клинических и исследовательских соображений в отношении нормативных и экономических ограничений. 10,000 известные РД оказывают коллективное воздействие 1 В 10 Американцы, в целом 30 million Люди. Ежегодно на РД приходится свыше

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… In the future, AI can align digital twin/avatar responses with patient features to estimate transport from bench to bedside and minimize the need for animal testing [ 66 ]. …

Effect of a Mobile App for the Pharmacotherapeutic Follow-Up of Patients With Cancer on Their Health Outcomes: Quasi-Experimental Study.

BackgroundOral antineoplastic agents (OAAs) have revolutionized cancer management. However, they have been reported with adverse side effects and drug-drug interactions. Moreover, patient adherence to OAA treatment is critical. Mobile apps can enable remote and real-time pharmacotherapeutic monitoring of patients, while also promoting patient autonomy in their health care.ObjectiveThe primary objective was to analyze the effect of using a mobile app for the follow-up of patients with oncohematological malignancies undergoing treatment with OAAs on their health outcomes. The secondary objective

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… However, unlike our app, ease of use was one of the least valued aspects, possibly because it is an app based on an avatar type game. …

A smartphone app to improve the safety of patients undergoing treatment with oral antineoplastic agents: 4 years of experience in a university hospital.

ObjectiveThis study aims to analyze the impact of the eOncosalud app on the management and follow-up of adverse effects (AE) in patients receiving oral antineoplastic agents.Material and methodsWe performed an observational, prospective study of cancer outpatients treated with oral antineoplastic agents (OAA), monitored by the eOncosalud app between August 2017 and October 2021. Safety variables were collected from eOncosalud: the number of AE; severity of the AE according to CTCAE, version 4.03; timelapse from app installation to first recorded AE; automatic recommendations issued; and the pa

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… The app has a daily 5-min routine avatar simulation video of lymphatic exercises providing a unique way of helping breast cancer survivors to establish their own self-care routine by following the video and educational material. | No direct communication with healthcare professionals. …

Longevity leap: mind the healthspan gap.

Life expectancy has increased by three decades since the mid-twentieth century. Parallel healthspan expansion has however not followed, largely impeded by the pandemic of chronic diseases afflicting a growing older population. The lag in quality of life is a recognized challenge that calls for prioritization of disease-free longevity. Contemporary communal, clinical and research trends aspiring to extend the health horizon are here outlined in the context of an evolving epidemiology. A shared action integrating public and societal endeavors with emerging interventions that target age-related m

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… Zebrafish patient avatars in cancer biology and precision cancer therapy. Nat. Rev. Cancer. 2020;20:263–273. doi: 10.1038/s41568-020-0252-3. 38. Boumahdi S, de Sauvage FJ. The great escape: tumour cell plasticity in resistance to targeted therapy. Nat. Rev. …

Геномика определяет злонамеренную трансформацию в условиях Миеломы.

Множественной миеломе (ММ) последовательно предшествует моноклонная гаммопатия неопределённого значения (МГУС) и множественная миелома (ШМ). Хотя эти прекурсоры являются асимптоматическими, они не являются полностью доброкачественными и сопряжены с риском продвижения к MM на протяжении всей жизни. В отличие от других раковых заболеваний, определяемых патологией, злокачественная трансформация от MGUS или SMM до MM до сих пор основывалась на демонстрации клинического ущерба конечной организации, поскольку морфология и цитогенетика не могут надежно их отличить. В настоящем исследовании используют

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… Moffitt: This research was made possible through the Oncology Research Information Exchange Network (ORIEN) Avatar Project in collaboration with Aster Insights (formerly known as M2Gen), the Total Cancer Care protocol, and supported by the NTRO, Tissue Core, Molecular Genomics, Cancer Pharmacokinetics …

The role of tumor types in immune-related adverse events.

Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block inhibitors of T cell activation and function. With the widespread use of ICIs in cancer therapy, immune-related adverse events (irAEs) have gradually emerged as urgent clinical issues. Tumors not only exhibit high heterogeneity, and their response to ICIs varies, with "hot" tumors showing better anti-tumor effects but also a higher susceptibility to irAEs. The manifestation of irAEs displays a tumor-heterogeneous pattern, correlating with the tumor type in terms of the affected organs, incidence, median onset time, and se

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… Al-Hamaly MA Turner LT Rivera-Martinez A Rodriguez A Blackburn JS Zebrafish cancer avatars: a translational platform for analyzing tumor heterogeneity and predicting patient outcomes Int J Mol Sci 2023 24 3 2288 36768609 10.3390/ijms24032288 PMC9916713 Al-Hamaly MA, Turner LT, Rivera-Martinez A, Rodriguez … Zebrafish cancer avatars: a translational platform for analyzing tumor heterogeneity and predicting patient outcomes. Int J Mol Sci. 2023;24(3):2288. 36768609 10.3390/ijms24032288 PMC9916713 18. …

Living and dying with incurable cancer: a qualitative study on older patients' life values and healthcare professionals' responsivity.

BackgroundIn ageing Western societies, many older persons live with and die from cancer. Despite that present-day healthcare aims to be patient-centered, scientific literature has little knowledge to offer about how cancer and its treatment impact older persons' various outlooks on life and underlying life values. Therefore, the aims of this paper are to: 1) describe outlooks on life and life values of older people (≥ 70) living with incurable cancer; 2) elicit how healthcare professionals react and respond to these.MethodsSemi-structured qualitative interviews with 12 older persons with advan

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… The themes and life values that arose from this research will be incorporated in a digital value clarification tool (in the form of a serious game; older adults who have advanced cancer can use this ‘game’ to learn about their values and preferences in ‘playful’ interaction with the game’s avatars. …

The functional imperative in high-grade glioma.

Precision oncology has emerged as a promising strategy for treating high-grade gliomas, yet its clinical impact has been disappointing, with over 300 clinical trials on targeted therapies failing to yield substantial improvements in patient outcomes. Current approaches primarily focus on static, marker-driven tumor features, which capture only a small portion of the complex biology that governs therapeutic responses. Functional precision oncology (FPO) offers a complementary approach, enhancing treatment selection in a personalized manner by dynamically testing patient-derived tumor cells agai

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… Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy. Cell Stem Cell 10.1016/j.stem.2024.11.010 (2024). 102. O’Neil, J. et al. An unbiased oncology compound screen to identify novel combination strategies. Mol. …

Targeting the gut microbiota to enhance the antitumor efficacy and attenuate the toxicity of CAR-T cell therapy: a new hope?

Chimeric antigen receptor (CAR) -T cell therapy has achieved tremendous efficacy in the treatment of hematologic malignancies and represents a promising treatment regimen for cancer. Despite the striking response in patients with hematologic malignancies, most patients with solid tumors treated with CAR-T cells have a low response rate and experience major adverse effects, which indicates the need for biomarkers that can predict and improve clinical outcomes with future CAR-T cell treatments. Recently, the role of the gut microbiota in cancer therapy has been established, and growing evidence

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… FMT from healthy human donors to preconditioned mice recapitulated the results obtained in naive gut microbiota mice. 16s Metagenomic analysis demonstrated that oral vancomycin affected the composition of human gut microbiome of engrafted avatar mice, with a significant decrease of alpha diversity and …

The role of AI in oncology: present applications and future horizons.

Artificial intelligence (AI) offers a powerful means to accelerate precision oncology by individualizing care in an era of rapidly evolving treatment paradigms. However, there is limited regulatory oversights for safe clinical implementation of AI, and concerns surrounding data bias, ownership, and privacy have hindered broad integration into healthcare practice. In this perspective, we offer a forward-looking roadmap for the dissemination of AI in oncology. We discuss the role for AI in guiding biomarker-driven patient selection for clinical trials and in facilitating both personalized drug s

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… Avatar: personalized precision radio-genomic theranostic oncology. Cancer Biother. Radiopharm . 10.1089/cbr.2025.0152 (2025). 10.1089/cbr.2025.0152 40576646 46. Niraula, D. et al. A decision support software for AI-assisted decision making in response-adaptive radiotherapy—an evaluation study. …

Erratum.

UNLABELLED: In the article The use of gaming technology for rehabilitation in people with multiple sclerosis, DOI: 10.1177/1352458514563593, … le tennis, boxing, archery, and sword fight) or displacements of the whole body to control the game avatar (ski slalom, balance bubble, penguin picnic, soccer heading, tilt city, and perfect ten). Table tennis, tennis, and tilt city were the preferred games. Single task (ST) exercises on the unstable platform group.Pre- and post-testing. Combination of s …