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Эпидемиологический и клинический курс по геморрагической лихорадке с ренальным синдромом в Новой эндемической зоне для гантавирусной инфекции в Хорватии.

Гантавирусы остаются важным примером новых и вновь возникающих инфекций в медицине человека. Цель этого исследования заключалась в анализе эпидемиологии, клинического представления и результатов хантавирусных инфекций в западной части Республики Хорватии, которая является новой географической зоной для хантавирусных инфекций. МЕТОДЫ: Ретроспективный анализ медицинских записей пациентов, лечившихся от геморрагической лихорадки с почечным синдромом (HFRS), в клинике инфекционных заболеваний Клинического больничного центра в Риеке, Хорватия, с 1 января 2014 года по 31 декабря 2021 года. РЕЗУЛЬТАТ

Совпадение в аннотации оригинала
BACKGROUND: Hantaviruses remain an important case of emerging and re-emerging infections in human medicine. This study aimed to analyse the epidemiology, clinical presentation, and outcome of hantavirus infections in the western part of Republic of Croatia, a new geographical area for hantavirus infections. METHODS: Retrospective analysis of medical records…

Serological Surveillance of Equine Leptospirosis in Croatia in the Period From 2012 to 2022: A Key Insight Into the Changing Epizootiology.

Leptospirosis is re-emerging zoonotic bacterial disease of global importance that affects domestic and wild animals and humans. Due to the public health importance, control of disease in Croatia is being implemented by monitoring the seroprevalence of equine leptospirosis and it is regulated by the law. In the period from 2012 to 2022, a total of 61,724 serum samples from apparently healthy horses were admitted to the Laboratory for leptospires, Faculty of Veterinary Medicine University of Zagreb. Serum samples were tested for Leptospira spp. antibodies using the microscopic agglutination test…

Prevalence and impact of pre-pregnancy body mass index on pregnancy outcome: a cross-sectional study in Croatia.

The aim of this study was to determine the association of maternal pre-pregnancy body mass index (BMI) and pregnancy outcome among pregnant women in Croatia. Women who gave birth in Croatia in 2017 were categorised into four groups according to pre-pregnancy BMI and analysed regarding maternal characteristics and perinatal outcomes. Among 32,051 pregnant women, 5.3% were underweight, 65.5% had normal BMI, 20.4% were overweight and 8.8% were obese. Overweight and obese women had a higher prevalence of induction of labour and delivery by caesarean section compared to normal-BMI women (p < .001),…

Trends of Late Presentation to Care in Patients with Chronic Hepatitis C during a 10-Year Period in Croatia.

Late presentation to care is the major obstacle to receiving treatment for chronic hepatitis C (CHC). Our aim was to analyze the prevalence and trends of late presenters (LP) at first consultations in Croatia during a 10-year period. This retrospective cross-sectional study included all adult CHC patients (n = 854) entering specialist medical care at the University Hospital for Infectious Diseases Zagreb between 2009 and 2018. LP was defined as liver stiffness measurement ≥ 9.5 kPa or biopsy METAVIR F ≥ 3. During the study period, mean patients' age increased from 37 to 52 years while HCV geno…

Prevalence and molecular epidemiology of West Nile and Usutu virus infections in Croatia in the 'One health' context, 2018.

In 2018, Croatia reported the largest outbreak of West Nile virus (WNV) infections as well as the re-occurrence of human Usutu virus (USUV) infections. For the first time, fatal WNV and USUV infections were detected in wild birds. We analysed epidemiological characteristics and molecular epidemiology of WNV and USUV infections detected during 2018 transmission season. From April to November, 178 patients with neuroinvasive disease and 68 patients with febrile disease were tested for WNV and USUV. Viral RNA was detected in cerebrospinal fluid (CSF) and urine samples using a real-time RT-PCR. Po…

Psychosocial adjustment to sex reassignment surgery: a qualitative examination and personal experiences of six transsexual persons in croatia.

In Croatia, transgender individuals face numerous social and medical obstacles throughout the process of transition. The aim of this study was to depict the factors contributing to the psychosocial adjustment of six transsexual individuals living in Croatia following sex reassignment surgery (SRS). A combination of quantitative and qualitative self-report methods was used. Due to the specificity of the sample, the data were collected online. Standardized questionnaires were used to assess mental health and quality of life alongside a series of open-ended questions divided into 4 themes: the de…

The prevalence and the risk factors of the cervical colonization by the genital mycoplasmas among pregnant women from Eastern Croatia.

The aim of this study was to determine the prevalence of the genital mycoplasmas cervical colonization among the pregnant women from the Eastern Croatia and to evaluate its correlation with the demographic and the behavioural risk factors. Study was conducted from March 2010 to April 2011 at the Microbiology Department of the Institute of Public Health for the Osijek-Baranja County. The study included 456 pregnant women in the first and the second trimester of pregnancy. Demographic data and data on their possible risk behaviour during the lifetime were collected with the usage of an anonymous…

Biochemical screening of fetal aneuploidies and neural tube defects by "double-test" in Croatia: a 10 years' experience.

The aim of the study is to investigate the efficiency of the second-trimester biochemical screening, with maternal serum alpha-fetoprotein (MS-AFP) and free beta-subunit of human chorionic gonadotropin (free beta-hCG), during the ten-year period. The study included 11,292 of pregnant women between the 15th and 18th gestational week, who underwent screening from November 1996 to December 2006. The risk for trisomy 21 and trisomy 18 were calculated by computer software, based on a model which generated the final risk for fetal aneuploidies from the pregnant woman's a priori age risk and the like

[The development of interventional catheterisation in the referral centre for pediatric cardiology of the Republic of Croatia--a retrospective study 1996-2009].

The goal of our study was to show an increase in the number of interventional heart catheterisations in the last 14 years in the Referral Centre for Pediatric Cardiology of the Republic of Croatia. From January 1996 to December 2009 2379 children (51% male and 49% female) underwent invasive diagnostic procedures (mean age 4.1+3.8 years, range 1 day-20.5 years). In that period in 22.27% (2379/530) of the children a certain interventional procedure was performed. The number of interventional catheterisations increased from 20/160 (12.5%) in 1996 to 70/224 (31.25%) in 2009. Some interventional pr…

Periodontal conditions and oral hygiene in rural population of post-war Vukovar region, Croatia in correlation to stress.

OBJECTIVE: The greatest burden of oral diseases is on the socially marginalized population, such as those living in small villages and war areas. The aim of this study was to assess the periodontal conditions of people in post-war area villages in relation to oral hygiene, habits and war stress. METHODS: The study was conducted on a sample of 282 subjects (mean age 41.5 +/- 17.8) in seven Vukovar villages using the questionnaire and clinical periodontal examination. RESULTS: Five years after the war in Croatia the population was still very poor, low educated, and had a low level of periodont…

A review of leishmaniasis in Dalmatia (Croatia) and results from recent surveys on phlebotomine sandflies in three southern counties.

Zoonotic visceral leishmaniasis (VL) is a re-emerging disease in the Mediterranean area. A historical review on human and canine leishmaniasis in Croatia documents the presence of stable disease foci in coastal and insular territories of central and southern Dalmatia since the beginning of the 20th century. We report on a 3-year entomological investigation (2002-2004) aimed to study the current species composition and seasonality of phlebotomine sandflies in 10 localities of Dalmatia. Standard blacklight traps employed for sampling Culicoides midges in the frame of bluetongue disease surveilla…

Study of MCPA and MCPP herbicides mobility in soils from North-West Croatia as affected by presence of fertilizers.

The mobility of acid herbicide (4-chloro-2-methylphenoxy)acetic acid [MCPA] and 2-(4-chloro-2-methylphenoxy)propionic acid [MCPA] in soils of North-West Croatia has been studied by soil thin-layer chromatography (STLC). Mobility of MPCA and MCPP was influenced by the change in concentration of soluble salts and the effect of mineral composition of the system studied, i.e. content of kaolin and sand in soil thin layer. The objective of this work was also to investigate how the mobility of phenoxy herbicides MCPA and MCPP is altered by the presence of fertilizers when both coexist in soil as a r…

Asymptomatic pharyngeal carriage of beta-haemolytic streptococci and streptococcal pharyngitis among patients at an urban hospital in Croatia.

In a one-year study at the University Hospital of Infectious Diseases in Zagreb, Croatia the rate of asymptomatic throat carriage of beta-haemolytic streptococci was investigated. Throat carriage was investigated in 1796 patients, none of whom had a sore throat nor signs and/or symptoms of a respiratory tract infection. The carrier rate of beta-haemolytic streptococci was 8.3%, for group A streptococci 6%, group B 1.3%, group C 0.3% and group F 0.1%. The highest rate was observed in the 6 to 14 year age group: 13.8% for all streptococcal groups, 11.7% for group A alone. The proportion of non-A…

Impact of the COVID-19 pandemic on university performance: a retrospective follow-up study of the University of Split, Croatia.

BACKGROUND: The COVID-19 pandemic has affected the academic performance, financial health, scientific output, and student and staff mobility of higher education institutions globally. Here, we report on a retrospective analysis of the core activities at the University of Split, Croatia, from 2017 to 2023, with a focus on the pandemic's impact thereon. METHODS: Using interrupted time series analysis, we examined trends in student success, research output, financial indicators, and mobility patterns before, during, and after the pandemic, with a total of 34 indicators. RESULTS: We found no sig…

Patients' awareness of the cardiovascular risk factors - results of the primary care arm of EUROASPIRE V study in Croatia.

BACKGROUND: Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality globally and in Croatia. Effective prevention relies on patient awareness and management of modifiable risk factors, yet the extent of patient knowledge regarding their own risk factor values and guideline-recommended targets is unclear. METHODS: This study analysed data from the Croatian primary care arm of the EUROASPIRE V survey, which included adults aged 18-79 years without established atherosclerotic disease but receiving treatment for hypertension, dyslipidemia, or diabetes. Patients were interv…

Radon levels in caves in Primorsko-goranska County, Croatia and assessment of the effective dose for visitors and tourist guides.

Radon is a natural source of radiation and one of the main causes of lung cancer. Since radon is a product of radium decay, it leaks from soil and rock and often accumulates in enclosed spaces. Caves are known for high radon concentrations, especially under certain meteorological conditions when the air circulation in the cave is weak. In this study, the results of radon monitoring in two caves in Croatia, Šparožna Cave and Biserujka Cave, are presented. Radon concentrations were measured continuously in each cave for 14 months. The monthly average concentrations showed a clear seasonal patter…

Molecular epidemiology and mechanisms of carbapenem and colistin resistance in Klebsiella and other Enterobacterales from treated wastewater in Croatia.

Among the most problematic bacteria with clinical relevance are the carbapenem-resistant Enterobacterales (CRE), as there are very limited options for their treatment. Treated wastewater can be a route for the release of these bacteria into the environment and the population. The aim of this study was to isolate CRE from treated wastewater from the Zagreb wastewater treatment plant and to determine their phenotypic and genomic characteristics. A total of 200 suspected CRE were isolated, 148 of which were confirmed as Enterobacterales by MALDI-TOF MS. The predominant species was Klebsiella spp.

Prevalence of Use and Knowledge about Tobacco Products and Their Harmful Effects among University Students in Southern Croatia.

Understanding students' attitudes toward smoking and tobacco products is essential for effective smoking prevention interventions. This questionnaire-based cross-sectional survey aims to determine the prevalence of use and knowledge about cigarettes, heated tobacco products, and electronic cigarettes and their harmful effects among university students. The survey was conducted using a self-administered online questionnaire among 1184 students. Questions were related to the respondents' demographic characteristics, tobacco use patterns, and opinions about exposure to health warnings and tobacco

Anger in Adulthood in Participants Who Lost Their Father During the War in Croatia When They Were in Their Formative Age.

BACKGROUND: Loss of parents in early childhood can have serious long-term psychological consequences. Abandoned by a close figure of attachment, many persons have developed the emotion of anger, even though the separation was caused by death. The traumatic experience of the loss of a parent is particularly hard in war, because most often it does not occur as an individual trauma. Our aim is to research anger as a personality trait in persons whose father had died in war at a time when they were children, and to compare it with an appropriate civilian control group of subjects. SUBJECTS AND ME

Risk factors for fatal outcome in patients with opioid dependence treated with methadone in a family medicine setting in Croatia.

AIM: To determine the risk factors for fatal outcome in patients with opioid dependence treated with methadone at the primary care level. METHODS: A group of 287 patients with opioid dependence was monitored prospectively from 1995 to 2007. At the beginning of the study, we collected the data on patient baseline characteristics, treatment characteristics, and living environment. At the annual check-up, we collected the data on daily methadone dose, method of methadone therapy administration, and family physician's assessment of the patient's drug use status. RESULTS: Out of 287 patients, 8%