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Ultrasound findings of Fitz-Hugh-Curtis Syndrome (FHCS) associated with splenic tuberculosis in an HIV-positive male patient.

Fitz-Hugh-Curtis (FHCS) is characterized by an inflammation of the hepatic capsule concomitant or following pelvic infection due to Chlamydia trachomatis or Neisseria gonorrhea. It is a rare condition occurring most often in a woman of childbearing age and very rare in male patients. Splenic involvement is also a rare form of abdominal tuberculosis. The association of these two conditions is very uncommon. We report the exceptional case of a 58- year-old HIV-positive male patient, with whom abdominal ultrasound helped diagnose FHCS associated with abdominal tuberculosis invovlving the spleen.

[Haemorrhagic proctocolitis as primary manifestation of lymphogranuloma venereum in an HIV-positive male].

This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. LGV is a se xually transmitted infection with a rising incidence among persons with risk behaviour. This case report underlines the importance, that all positive rectal screenings for Chlamydia trachomatis should be routinel…

Azithromycin levels in cervical mucus and plasma after a single 1.0g oral dose for chlamydial cervicitis.

OBJECTIVE: To determine the kinetics of azithromycin in cervical mucus and plasma. SUBJECTS AND METHODS: Azithromycin concentrations were determined in plasma and mucus samples from 20 women with cervical chlamydial infection one, seven and fourteen days after a single oral 1.0 g dose. RESULTS: In mucus, all measurable azithromycin concentrations were above the minimal inhibitory concentration against Chlamydia trachomatis on day 7 as well as on day 14. CONCLUSION: The high cervical mucus concentrations of azithromycin can explain the high clinical and microbiological efficacy.

Advances in diagnostic testing for vaginitis and cervicitis.

An accurate diagnosis of vaginal and cervical infection is the key to proper treatment. New tests are available to aid in the diagnosis of b … rally more rapid but less accurate than culture for the identification of Neisseria gonorrhoeae and Chlamydia trachomatis.

В vivo оценка окулярных вставок гидрогеля, пропитанного антибиотиками для трахомной терапии.

Устойчивый выпуск антибиотиков из гидрогельных матриц в глаз был изучен в целях разработки нового метода лечения трахомы. Кополимеры N-винилпиролидона были сформированы в окулярную вставку и пропитаны эритромицином или эритромицином. Антибиотико-гидрогель полностью подавляет хламидиозную инфекцию трахоматиса в глазах совы. Показатели злоупотребления наркотиками были немного ниже в vivo, чем в vitro. По сравнению с уровнем утечки наркотиков в человеческий глаз и в совы обезьяньего глаза ожидается аналогичный терапевтический эффект при лечении трахомы человека.

Совпадение в аннотации оригинала
Sustained release of antibiotics from hydrogel matrices in the eye was studied for the purpose of developing a new method for trachoma therapy. Copolymers of N-vinylpyrrolidone were moulded into an ocular insert and impregnated with erythromycin or erythromycin estolate. The antibiotic-hydrogel inserts completely suppressed the chlamydia trachomatis infectio…

[Bacteriological finding in the urethra in men with and without non-gonococcal urethritis].

BACKGROUND/AIM: Non-gonococcal urethritis (NGU) is a very common sexually transmitted disease. The etiology of the disease is complex and no … addition to standard bacterial examination and performinig direct imunofluorescence test to detect Chlamydia trachomatis (bioMerieux, France), urethral smears were also examined for the presence of Ureaplasma urealyticum and Mycoplasma hominis by commercially available Mycofast Evolution 2 test (International Microbio, France). The finding of mycoplasmas > or = 10(4) …

Anorectal lymphogranuloma venereum (LGV) circulation dynamics in Buenos Aires: Nine-year surveillance and therapeutic implications.

BackgroundLymphogranuloma venereum (LGV), caused by Chlamydia trachomatis L-genotypes, has re-emerged as a major anorectal infection in men who have sex with men (MSM), especially in people living with HIV. Distinguishing LGV from non-LGV C. trachomatis is essential because LGV requires 3 weeks of doxycycline. Long-term Latin American data are lacking.MethodsAnorectal swabs from patients with suspected anorectal sexually transmitted infections were studied in a cross-sectional study conducted at two Buenos Aires coloproctology referral centers (August 2017-November 2025). Anorectal swabs were …

Maternal exposure to sexually transmitted infections and schizophrenia among offspring.

Animal models and epidemiologic studies suggest that prenatal maternal infection, and sexually transmitted infection (STI) in particular, is associated with an increased risk of schizophrenia in the offspring. However, findings from prior research studies on common infections, including herpes simplex virus type 2 (HSV-2) and Chlamydia trachomatis (C. trachomatis) have been inconsistent. To investigate these associations, we conducted a case-control study nested in the population-based Finnish Prenatal Study of Schizophrenia. Using linked national registries, 963 cases with schizophrenia (ICD-…

Time from first intercourse to first sexually transmitted infection diagnosis among adolescent women.

OBJECTIVE: To determine the time between first intercourse and first sexually transmitted infection (STI) with Chlamydia trachomatis, Neisseria gonorrhoeae, or Trichomonas vaginalis and time between repeated infections. DESIGN: Observational study. SETTING: Three adolescent medicine clinics. PARTICIPANTS: A cohort of 386 urban young women aged 14 to 17 years at enrollment. MAIN OUTCOME MEASURES: Age at first intercourse; organism-specific interval between first intercourse and first STI diagnosis; interval between repeated infections; and age at first STI test prior to study participation.…

Sexually transmitted and reproductive tract infections in symptomatic clients of pharmacies in Lima, Peru.

OBJECTIVE: To determine prevalences and predictors of sexually transmitted and reproductive tract infections among men and women seeking care at pharmacies. METHODS: Men and women with urethral discharge or dysuria and vaginal discharge were enrolled at 12 central and 52 smaller pharmacies in Lima, Peru. All participants answered a questionnaire. Men provided urine for polymerase chain reaction (PCR) testing for Neisseria gonorrhoeae and Chlamydia trachomatis, and for leucocyte esterase testing. Women provided self-obtained vaginal swabs for PCR testing for N gonorrhoeae and C trachomatis, Tr…

Haemophilus influenzae Urethritis: A Localization to Consider.

Urethritis may be acute or subacute and can be classified as gonococcal or nongonococcal. Nongonococcal urethritis is mainly dominated by Chlamydia trachomatis. Other bacteria such as Haemophilus influenzae have been implicated in some cases. We report the case of a 56-year-old diabetic man with H. influenzae urethritis following unprotected oral sex. The patient initially received treatment with ciprofloxacin, but this proved to be ineffective. Once our diagnosis was made, we switched the patient to cefixime for a period of seven days, which resulted in a successful clinical outcome.

The silent epidemic of lymphogranuloma venereum inside the COVID-19 pandemic in Madrid, Spain, March 2020 to February 2021.

Despite social distancing measures implemented in Madrid to prevent the propagation of SARS-CoV-2, a significant increase (57.1%; 28.5 to 38.5 cases/month) in cases of lymphogranuloma venereum was detected during the COVID-19 pandemic. This unusual scenario might have accelerated a shift in Chlamydia trachomatis (CT) epidemiology towards a higher proportion of L genotypes compared with non-L genotypes in CT-positive samples. Our data underscore the importance of surveillance of sexually transmitted infections during the pandemic, in particular among vulnerable populations.

The great imitator, revisited.

Our study shows an atypical presentation of primary syphilis inappropriately treated with surgery: a 36-year-old male visited our clinic for a consultation 2 weeks after surgery, since he had noticed a recurrent lesion on the glans head of the penis. Clinical data, histologic pictures and serological tests, confirmed the diagnosis of an atypical presentation of primary syphilis; in addition, Chlamydia trachomatis infection was found. The patient was started on a course of doxycycline 100 mg tablets, twice daily for 4 weeks. At follow up, there was complete remission.

Time to re-evaluate the guidance on sexual infections in fertility services.

Current guidance in the UK for fertility services on the screening for sexually transmitted infections (STI) is solely directed towards Chlamydia trachomatis. Evidence used to formulate the guidance is based on research undertaken before more sensitive diagnostic methods were available and before testing of some organisms was even possible. This commentary outlines current STI trends, evidence available for STI effect on fertility and new diagnostic methods of screening. It aims to demonstrate that UK guidance should be updated and directed towards areas where further research is required.

A review of current guidelines and research on the management of sexually transmitted infections in adolescents and young adults.

Adolescents and young adults are at high risk for sexually transmitted infections (STIs). Providers have the responsibility to accurately manage these infections to prevent medical complications and the spread of STIs. This article will review the epidemiology, screening recommendations, diagnostic tests, and treatment guidelines for STIs most commonly encountered in this population: Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes simplex virus, and Trichomonas vaginalis, as well as the sexually associated infection bacterial vaginosis. This review will discuss ongoing research that explo…

Doxycycline failure in lymphogranuloma venereum.

Lymphogranuloma venereum (LGV) cases are currently re-emerging in the homosexual community, particularly in HIV-seropositive patients. The standard treatment for this infection, which is caused by Chlamydia trachomatis L1, L2 and L3 serotypes, is a 3-week doxycycline regimen. The case is reported of a male patient presenting with LGV, who was rapidly cured with moxifloxacin treatment after failure of extended treatment with cyclines. This fluoroquinolone is known to be highly active in vitro on the LGV pathogenic agent. Thus it may be a useful alternative when doxycycline treatment results in …

The emergence of LGV in Western Europe: what do we know, what can we do?

Lymphogranuloma venereum (LGV), a systemic sexually transmitted disease (STD) caused by a variety of the bacterium Chlamydia trachomatis, occurs rarely in the Western world [1]. However, in January 2004, public health officials in the Netherlands noted an outbreak of cases of LGV proctitis among men who have sex with men (MSM) [2]. Since then, cases have been reported from several European countries, and the United States of America and Canada. In this issue three countries report on the current status of LGV [3-5].

[Results of the microbiological, clinical and immunological examination of children with Reiter's disease].

Infectious agents were detected in 100% of examined children with Reiter's disease (RD). Chlamydia trachomatis were detected in 98% of cases. In children with RD lesions of joints and eyes often took acute forms with cases of sacroiliitis, early muscular atrophy and conjunctivitis. In 95% of the patients the prostatitis manifestations were detected. In children with RD a rised number of CD lymphocytes in combination with the fivefold rised IL-4 content, an essential increase in the activity of C2-C5 components of the complement and a multiple rised level of PSA were registered.

Lymphogranuloma venereum presenting as a rectovaginal fistula.

Lymphogranuloma venereum (LGV) is a rare form of the sexually transmitted disease caused by Chlamydia trachomatis. In the United States, there are fewer than 350 cases per year. In a review of the world's literature, there has not been a case reported in the last thirty years of a case of LGV presenting as a rectovaginal fistula. We present a case of an otherwise healthy American woman who presented with a rectovaginal fistula. Although uncommon, LGV does occur in developed countries and may have devastating tissue destruction if not recognized and treated before the tertiary stage.

Tampon sampling for diagnosis of bacterial vaginosis: a potentially useful way to detect genital infections?

Genital tract infections are important causes of ill health in developing countries, but diagnosis is difficult. Bacterial vaginosis (BV) was correctly diagnosed by using a vaginal specimen obtained by tampon sampling in 22 of 24 women (91.6%) for whom BV was diagnosed by Gram staining. The yield for other vaginal infections was higher (28% for Trichomonas vaginalis and 32.7% for Candida albicans) than it was for cervical infections (0% for Neisseria gonorrhoeae and 30% for Chlamydia trachomatis). Tampon sampling was acceptable to patients and may facilitate diagnosis of genital infections in …