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Attachment Styles and Sexual Function Among Survivors of Autologous Hematopoietic Stem Cell Transplantation: A Multicenter Study.

Background and Objectives: Autologous hematopoietic stem cell transplantation (AHSCT) offers life-saving treatment for hematologic malignancies but can result in persistent sexual dysfunction and relationship challenges. Attachment theory provides a valuable framework for understanding how enduring relational patterns influence sexual well-being. This study aimed to assess sexual function and attachment styles in AHSCT survivors and examine correlations between attachment and sexual health outcomes. Materials and Methods: A multicenter, cross-sectional study was conducted from December 2019 to

Корреляции неточностей в сообщении о поглощении энергии среди лиц с множественным склерозом.

Лица с множественным склерозом (МС) заинтересованы в рационе питания в качестве второго подхода к лечению заболеваний. В этом исследовании были изучены потенциальные переменные, которые соотносятся с неточностью данных о самопоглощении энергии (ЭИ) у взрослых с МЗ. МЕТОДЫ: Twenty-eight Число завершенных участников two назначений в рамках системы Организации 14-day b) период, который включал стандартный протокол с двойной маркировкой воды (ДЛВ) для оценки общих расходов на энергию (ПЭЭ). Участники сообщили о том, что они используют автоматизированную систему самоуправления 24 h (ASA24) Инструме

Результаты перкутановой вертебропластики в множестве миеломы: опыт третичной нейрофизики в долгосрочной последующей деятельности.

Множественная миелома диагностируется в 5,800 ежегодно в Соединенном Королевстве (Соединенном Королевстве) 64% - иметь переломы позвоночника при диагностике. Больные переломы позвоночника могут нанести значительный ущерб качеству жизни пациентов. Перкутанная вертебропластика направлена на обеспечение долгосрочного обезболивания и стабилизацию перелома позвонков. МЕТОДЫ И МАТЕРИАЛЫ: Данные были собраны по всем случаям перкутановой вертебропластики, выполненной пациентами с множественной миеломой с ноября 2017 по январь 2019. Показатели боли измерялись по шкале Визуального Аналога (VAS) и предпр

Measuring Frailty Using Patient-Reported Outcomes (PRO) Data: A Feasibility Study in Patients with Multiple Myeloma.

PURPOSE: The objective of this retrospective study was to determine the feasibility of measuring frailty using patient responses to relevant EORTC QLQ-C30 items as proxy criteria for the Fried Frailty Phenotype, in a cohort of patients with Relapsed/Refractory Multiple Myeloma (RRMM). METHODS: Data were pooled from nine Phase III randomized clinical trials submitted to the FDA for regulatory review between 2010 and 2021, for the treatment of RRMM. Baseline EORTC QLQ-C30 responses were used to derive a patient-reported frailty phenotype (PRFP), based on the Fried definition of frailty. PRFP wa

Виртуальная реалити-ческая подготовка по расстройствам похода в болезни Паркинсона: библиометрический и визуальный анализ горячих точек и тенденций с использованием CiteSpace и VOSviewer.

В настоящем исследовании на систематической основе рассматривается нынешнее положение дел, распределение горячих точек и тенденции развития виртуальных реалити-шоу (ВР) в целях совершенствования хитроумных расстройств в болезни Паркинсона. 2008 и 2025 был извлечен из баз данных " Web of Science " , " PubMed " и " CNKI " . В конечном счете, 535 Английский 18 Были включены китайские статьи. CiteSpace и VOSviewer использовались для визуального анализа тома публикаций, сетей сотрудничества (страны, авторы и учреждения), ключевых слов, группирования и вспыльчивых терми

A Pilot Randomized Controlled Trial and Multi-Omics Analysis of Electrolysed Alkaline Water: Impacts on Gut Microbiota and Metabolic Signatures in Hyperuricemia.

Background/Objectives: Hyperuricemia (HUA) is the second most common metabolic disease in China (24.5% in males, 3.6% in females), which can induce multiple complications such as gout and diabetes. Existing urate-lowering drugs have significant hepatorenal toxicity, necessitating safe lifestyle interventions. Electrolyzed alkaline water (EAW) as daily drinking water has shown preliminary effectiveness, but it lacks randomized controlled evidence and mechanistic studies at the microbiome-metabolome interface. Methods: We conducted a 12-week randomized controlled trial in 40 adults aged 18-65 ye

Резюме докладов 2017 Ежегодное совещание Общества общей внутренней медицины.

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Деменция, расстройства настроения и старение.

С повышением возраста и продолжительности жизни в мире как в развитых, так и в развивающихся странах риск развития когнитивных потерь и расстройств настроения значительно возрастает в той мере, в какой после достижения возраста 65, этот риск почти удваивает каждый 5 Спустя годы. В результате, соответствующий рост неинфекционных заболеваний поразит людей со слабоумием и расстройствами настроения, связанными с болезнью Альцгеймера, множественным склерозом, депрессией и тревогой. На клинической основе многочисленные факторы риска и представления, которые связаны с утратой интеллектуальных способн

Comprehensive update on cancer scenario of Bangladesh.

Bangladesh, at 142 million people, is the ninth most populous country in the world. There are 13 to 15 lakh cancer patients in Bangladesh, with about two lakh patients newly diagnosed with cancer each year. As an overview, lung cancer and mouth-oropharynx cancer rank as the top two prevalent cancers in males. Other types of cancers are esophagus cancer and stomach cancer. In women, cancer cervix uteri and breast cancer are most prevalent. Other cancer types, which affect women, are mouth and oropharynx cancer, lung cancer, and esophagus cancer. There are around 150 qualified clinical oncologis

Artificial Intelligence-Augmented Propensity Score, Cost Effectiveness and Computational Ethical Analysis of Cardiac Arrest and Active Cancer with Novel Mortality Predictive Score.

Background and objectives: Little is known about outcome improvements and disparities in cardiac arrest and active cancer. We performed the first known AI and propensity score (PS)-augmented clinical, cost-effectiveness, and computational ethical analysis of cardio-oncology cardiac arrests including left heart catheterization (LHC)-related mortality reduction and related disparities. Materials and methods: A nationally representative cohort analysis was performed for mortality and cost by active cancer using the largest United States all-payer inpatient dataset, the National Inpatient Sample,

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… They contribute to worse health and health risks than other social groups (whose greater social advantage or relative position in latent social hierarchies typically confers greater resiliency (to social and personal shocks_ and social mobility and influence to pursue one’s ends (through greater prestige …

Identification of actions to be taken by managers to facilitate the return to work of cancer survivors: Consensus between managers and cancer survivors.

BackgroundManagers are considered to be main stakeholders in the return to work (RTW) of cancer survivors. However, the perspectives of cancer survivors and managers differ on what managerial actions should be taken during the RTW of cancer survivors. This difference might put effective collaboration and successful RTW at risk. Therefore, this study aims to reach consensus among managers and cancer survivors on the managerial actions to be taken during the four different RTW phases of cancer survivors (i.e., Disclosure, Treatment, RTW plan, Actual RTW).MethodsThe Technique for Research of Info

The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review.

Objective: Response-shift has been cited as an important measurement consideration when assessing patient reported quality of life (QoL) outcomes over time among patients with severe chronic conditions. Here we report the results of a systematic review of response shift in studies assessing QoL among cancer patients. Methods: A systematic review using MEDLINE, EMBASE, and PsychINFO along with a manual search of the cited references of the articles selected, was conducted. A quality review was performed using STROBE criteria and reported according to PRISMA guidelines. Results: A systematic rev

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015. METHODS: We estimated incid

Quality of Life in Palliative Care: A Systematic Meta-Review of Reviews and Meta-Analyses.

BackgroundThe area of palliative care is a setting in which the evaluation of the quality of life (QoL) is fundamental. However, the topic has been covered from many different points of view, and there is a lack of comprehensive synthesis of the evidence drawn from the available literature.ObjectiveWe carried out a meta-review of all available systematic reviews and meta-analyses that have dedicated part or most of the investigation to the assessment of QoL in palliative care to provide the most updated and comprehensive depiction of all available information about measurement and intervention

The Five "Ws" of Frailty Assessment and Chronic Lymphocytic Leukemia: Who, What, Where, Why, and When.

Chronic lymphocytic leukemia (CLL) is a disease of the elderly, but chronological age does not accurately discriminate frailty status at the inter-individual level. Frailty describes a person's overall resilience. Since CLL is a stressful situation, it is relevant to assess the patient´s degree of frailty, especially before starting antineoplastic treatment. We are in the era of targeted therapies, which have helped to control the disease more effectively and avoid the toxicity of chemo (immuno) therapy. However, these drugs are not free of side effects and other aspects arise that should not

Post-traumatic growth after cancer: a scoping review of qualitative research.

PurposeInterest is growing in post-traumatic growth (PTG) after cancer prompted, in part, by observations of positive associations with health-related quality of life. Qualitative research provides valuable insight into survivors' experiences. We conducted a scoping review of qualitative evidence on PTG in cancer, determining the number, nature, range and scope of studies, and gaps in the literature.MethodsWe systematically searched Medline, Scopus, CINAHL, Web of Science, and PsycINFO for qualitative research exploring positive changes after cancer published from 1996. From eligible studies,

Abstracts from the 37th Annual Meeting of the Society of General Internal Medicine, 2014, San Diego, CA, USA.

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Interpersonal emotion regulation and mental health among cancer survivors: A systematic review.

ObjectiveCancer and its treatment can cause significant emotional distress, adversely affecting mental health. Interpersonal emotion regulation, the process by which individuals regulate emotions through social interactions, plays a critical role in cancer survivorship. This study systematically reviews evidence on the associations between interpersonal emotion regulation and mental health outcomes among cancer survivors, along with the theoretical models guiding this research.MethodsA systematic search was conducted in PubMed, Embase, Web of Science, and Scopus databases, yielding 6928 record

Изучение перспектив потребителей услуг в области здравоохранения на пути к интеграции питания в рутинную помощь с множественным склерозом: качественное исследование.

КОЛИЧЕСТВО: Люди, страдающие множественным склерозом, рассчитывают получить информацию о питании от медицинских работников (HCP), с тем чтобы самостоятельно справиться со своим заболеванием. Цель этого исследования заключалась в изучении опыта ПМСО в области обеспечения ухода, связанного с питанием, и в обеспечении понимания их потребностей и предпочтений в отношении того, каким образом его можно было бы обеспечить в рамках обычного ухода. МЕТОДЫ: Это качественное исследование, опирающееся на интерпретационный феноменологический подход, было проведено с использованием онлайновых целевых групп

It's never too late - balance and endurance training improves functional performance, quality of life, and alleviates neuropathic symptoms in cancer survivors suffering from chemotherapy-induced peripheral neuropathy: results of a randomized controlled trial.

BackgroundChemotherapy-induced peripheral neuropathy (CIPN) can affect functional performance and quality of life considerably. Since balance training has proven to enhance physical function, it might be a promising strategy to manage CIPN-induced functional impairments.MethodsFifty cancer survivors with persisting CIPN after finishing their treatment were randomly allocated to an intervention (IG) or active control group (CG). The IG did endurance plus balance training, the CG only endurance training (twice weekly over 12 weeks). Pre- and post-assessments included functional performance, card