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Упорное использование опиоидов связано с более коротким выживанием миэломы.

Цель " Превышение " содержания опиоидов связана со значительным кризисом в области общественного здравоохранения, однако по-прежнему имеет решающее значение в качестве адъюнкт-процесса лечения во многих миеломах (ММ). Остаются вопросы о балансе между выгодами от продолжающегося использования опиоидов, особенно когда миэлома пациента находится в ремиссии. Этот ретроспективный обзор посвящен ассоциации хронического опиоида (COU) среди пациентов, преимущественно цветных. 174 В одном из городских медицинских центров были изучены пациенты, получившие аутологическую трансплантацию стволовы

Тенденции в области множественной смертности от миеломы и сердечно-сосудистых заболеваний среди пожилых людей в Соединенных Штатах, 1999 в адрес 2023:: анализ базы данных ЦКЗ " Удивительно " .

Множественная миелома (ММ) в значительной степени связана с сердечно-сосудистыми осложнениями, и их совместное существование значительно повышает риск сердечно-сосудистых заболеваний и смертности, главным образом среди пожилых людей. Поэтому мы намерены проанализировать тенденции смертности от MM и сердечно-сосудистых заболеваний (CVD) среди пожилых людей, 1999 в адрес 2023 В Соединенных Штатах (США) был проведен ретроспективный анализ базы данных центров по борьбе с заболеваниями и их профилактике (CDC WONDER) с использованием широкополосных онлайновых данных для целей эпидемиологических иссл

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… Gender disparities of heart disease and the association with smoking and drinking behavior among middle-aged and older adults, a cross-sectional study of data from the US health and retirement study and the China health and retirement longitudinal study . …

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial.

AimCancer remains a disease with a significant impact on morbidity and mortality but also on quality of life. This prospective randomized pilot study investigated the effects of a sound intervention on physical and emotional well-being in outpatients with cancer.MethodsTwo self-applied sound interventions were used for this purpose, either active "music playing" with a body monochord or passive sound intervention with headphones to listen to a given music compilation. Interventions were carried out over a period of 4 weeks for at least 15 min in the evening before bedtime. The following self-a

Оценка иглоукалывания и аурикулотерапии при борьбе с тошнотой и рвотой, вызванной химиотерапией: экспериментальное исследование.

ЦЕЛЬ: Оценка эффективности иглоукалывания и аурикулотерапии в деле уменьшения тошноты, вызванной химиотерапией, и рвоты у больных раком, по сравнению с антиэметическим протоколом. МЕТОД: Пилотное исследование прагматического two- Клинические испытания с применением огнестрельного оружия: группа иглоукалывания получила системную иглоукалывание, аурикулотерапию и антиеметический протокол; контрольная группа использовала антиеметический протокол. Образец состоял из: 42 больные раком желудочно-кишечной системы или множественной миеломой. Результаты были оценены с помощью инструмента химиотерапии п

Insights from Social Media on the Patient Experience of Living With Rare Eosinophil-Driven Diseases.

Eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES) are driven by persistently high eosinophil numbers, causing damage to tissues and organs. As rare diseases, they are often underappreciated by healthcare professionals. Using a social listening analysis, we collected patient and caregiver comments relating to EGPA and HES made on online social platforms between 1 January 2019 and 31 May 2020, in English, French, and German. Results were classified into key areas of interest. In total, 746 comments with consent to publish were collected mentioning EGPA, an

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… “My husband has a rare illness EGPA, he has to get infusion treatments…when it gets worse… We have gone [through] our retirement savings paying for medications.” | “After a decade of getting steadily sicker with few doctors taking it seriously, my health was largely wrecked…” “[After receiving treatment … One caregiver of a patient with EGPA in the United States shared, “My husband has a rare illness EGPA, he has to get infusion treatments …We have gone [through] our retirement savings paying for medications.” …

Patient-reported pain severity and health-related quality of life in patients with multiple myeloma in real world clinical practice.

BACKGROUND: The association between patient self-reported pain severity and health-related quality-of-life (HRQoL) is poorly understood. AIMS: This real-world study of symptomatic multiple myeloma (MM) patients sought to determine how pain severity from a single question asked during routine clinical consultation was associated with HRQoL. METHODS AND RESULTS: Point-in-time data on HRQoL of 330 patients with MM (median age 70 years) receiving anti-myeloma therapy in Germany and Italy from November 2017 through February 2018 were analyzed. HRQoL was assessed using validated questionnaires (Wo

Opioid-Induced Constipation among a Convenience Sample of Patients with Cancer Pain.

BACKGROUND: Little is known regarding the burden of opioid-induced constipation (OIC) among patients who suffer from cancer-related pain. METHODS: A prospective longitudinal study was conducted among cancer patients in the United Kingdom (UK), Canada, and Germany, which included medical record data abstraction, Internet-based patient surveys, and physician surveys. Patients on daily opioid therapy (≥30 mg for ≥4 weeks) for treatment of cancer pain with self-reported OIC were recruited. Response to laxatives was defined by classifying participants into categories of laxative use and evaluating

Patient Perspectives on Health Insurance Design: A Mixed-Methods Analysis.

There remains a persistent lack of patient-centered evidence on insurance reform and real-world experiences of patients with chronic disease. This study gathered insights around insurance design from chronic disease beneficiaries. This mixed-methods analysis comprised an online survey and virtual focus group sessions (August to December 2023) involving US residents with chronic disease and health insurance. Patients' perspectives on insurance design were explored. Survey data were analyzed descriptively. Key themes were identified from focus group transcripts and direct observations. In total,

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… In the focus groups, participants shared more in-depth perspectives about the nature of their satisfaction changing over time and fluctuating with life events such as retirement, which would usually necessitate a change in insurance coverage. … “[Medicare catastrophic care] been very economical for what I pay in my premium that’s deducted from my retirement. The dollar-for-dollar value is by far much more than it was when I had the private insurance, when I was working for many years. …

Potential health and economic impact of achieving Kenya's overweight and obesity reduction target: a modelling study.

IntroductionKenya has adopted the WHO target of halting the rise of overweight, including obesity, by 2025. This paper assesses the potential impact of achieving the set target on health, healthcare cost and productivity.MethodsWe used a proportional multistate life table model (Kenya Obesity Model) to simulate the 2019 population of Kenya over their lifetime. We compared a scenario in which body mass index (BMI) distributions stabilise in 2025 against one whose BMI distributions stabilise in 2044, and quantified changes in disease-specific health outcomes, healthcare costs and productivity. W

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… First, to estimate productivity gains resulting from a reduction in high BMI-related mortality, we use the methodology previously used in Nomaguchi et al . 32 Productivity gains are estimated from the age of premature death until the age of traditional retirement in Kenya (65 years). … Obesity increases costs with productivity loss due to disability retirements, independent of physical activity: a cohort study. J Occup Environ Med. 2020;62:325–30. doi: 10.1097/JOM.0000000000001808. 36. Carter HE, Schofield DJ, Shrestha R, et al. …

Presumptive Prostate Cancer Presenting as Low Back Pain in the Chiropractic Office: Two Cases and Literature Review.

Prostate cancer is a common type of cancer in men and may metastasize to the spine and pelvis, causing back and/or radicular pain that appears to be musculoskeletal. This presents a diagnostic challenge and can be complicated by a lack of routine screening for prostate cancer. In two similar cases, elderly males (ages 78 and 82) with no known history of cancer and no previous prostate-specific antigen screening presented to a chiropractor with chronic, worsening radiating low back pain. In each case, a previous provider obtained radiographs and ascribed symptoms to a non-cancerous etiology (i.

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… As a retired businessman, the patient had engaged in weightlifting and hiking for the past 15 years since retirement. He noted that symptoms began and progressively worsened after a hiking trip and were exacerbated by weightlifting and jogging. …

Множественный склероз в Германии: анализ данных об административной распространенности и оказании услуг в области здравоохранения в официальной системе здравоохранения.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Данные об использовании медицинских услуг в связи с множественным склерозом (МС) в Германии являются недостаточными. Цель этого исследования заключалась в анализе административной распространенности НР, использования лекарств и типов специалистов, занимающихся лечением НР в амбулаторных условиях в Баварии. МЕТОДЫ: Были использованы данные о Псевудонимных претензиях, представленные баварскими врачами, аккредитованными в системе обязательного медицинского страхования (ШСИ). Согласно определению, административная распространенность НР имеет ≥1 Диагноз MS (Международная клас

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… Two-fifths of the total cost are related to decreased productivity owing to sick leave and early retirement, while mean direct healthcare costs are €17,165, demonstrating that MS is a major healthcare burden in Germany [ 8 ]. … Patients were identified based on their insurance number, which remains fixed during a period of insurance with a particular provider, but can change, for example in the case of marriage, retirement or health-insurance mergers. …

Treatment landscape and disease burden of patients with multiple myeloma in Japan: a real-world survey.

AIM: Multiple myeloma (MM) is a hematological malignancy associated with poor health-related quality of life (HRQoL). Safe and effective treatments for MM are limited. There is a need for real-world data to improve understanding of treatment patterns and sequencing in routine clinical practice in Japan. This study evaluated disease burden, treatment patterns, treatment sequencing, and reasons for treatment selection in patients with MM in Japan. METHODS: This analysis used survey data of hematologists or hemato-oncologists and their adult patients with MM who received active treatment in a re

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… of data collection, n (%) Never smoked 149 (48) 43 (48) 35 (46) 34 (47) 37 (52) Ex-smoker 86 (28) 32 (36) 24 (32) 14 (19) 16 (23) Current smoker 6 (2) 2 (2) 1 (1) 2 (3) 1 (1) Unknown 68 (22) 13 (14) 16 (21) 22 (31) 17 (24) Employment status at the point of data collection, n (%) Not working due to retirement … Most patients were either retired (29%; 89/309), unemployed (28%; 86/309) or a homemaker (20%; 61/309). …

Физическая пригодность пациентов с хроническими лимфоидами, получающих терапию, основанную на Моноклональной антителной терапии: тематическое исследование.

Введение: Гематологическая недостаточность составляет значительную долю глобального бремени раковых заболеваний. Иммунотерапия в настоящее время one :: основные методы лечения, используемые при лечении этих заболеваний. Цель: Цель этого исследования заключалась в оценке физической пригодности пациентов с хроническими лимфоидными заболеваниями, получающих моноклонную антителную терапию, по сравнению с здоровыми людьми. Материалы и методы: Исследование включало в себя 99 амбулаторные пациенты лечатся от гематологии malignancies-33 с хронической лимфоцитной лейкемией, 32 с несколькими миэлома, и

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… In the case of employment, one possible explanation is that patients with hematological malignancies may retire earlier because of disease-related limitations or eligibility for retirement and disability benefits. …

Construction and validation of nomogram prediction model for anxiety and depression in chemotherapy patients with multiple myeloma.

ObjectiveTo construct and validate a nomogram prediction model for anxiety and depression in chemotherapy patients with multiple myeloma (MM).MethodsFrom May 2021 to May 2023, 333 MM chemotherapy patients treated at our hospital were selected. The patients were randomly divided into a modeling group and a validation group in a 7:3 ratio (using a random number table method). According to whether the modeling group patients had anxiety and depression, they were grouped into a non-anxiety and depression group and an anxiety and depression group; a nomogram model constructed using R software was b

Development and Implementation of an Advanced Practitioner-Led Survivorship Clinic for Patients Status Post Allogeneic Transplant.

BackgroundSurvivor recovery from hematopoietic cell transplantation (HCT) is long term, with significant physical and psychological morbidities that impact quality of life and reentry into personal and social lives. The optimal timing of when and how to deliver comprehensive HCT survivorship care is not well defined.PurposeThe purpose of this study was to design, implement, and evaluate an advanced practitioner (AP)-led pilot survivorship clinic incorporating an individual and group format for patients post HCT at the 1-year transition period.MethodsA survey assessing physical, social, emotion

Understanding In-Person and Online Exercise Oncology Programme Delivery: A Mixed-Methods Approach to Participant Perspectives.

Alberta Cancer Exercise (ACE) is an exercise oncology programme that transitioned from in-person to online delivery during COVID-19. The purpose of this work was to understand participants' experiences in both delivery modes. Specifically, survivors' exercise facilitators and barriers, delivery mode preference, and experience with programme elements targeting behaviour change were gathered. A retrospective cohort design using explanatory sequential mixed methods was used. Briefly, 57 participants completed a survey, and 19 subsequent, optional interviews were conducted. Most participants indic

An inpatient Serious Illness Care Program for older patients with hematologic malignancies: a single-arm pilot study.

AbstractThe Serious Illness Care Program (SICP) is an evidence-based intervention designed to systemically implement serious illness conversations (SICs) into clinical practice. We previously piloted the SICP via telehealth for patients in the ambulatory setting. However, many patients with hematologic malignancies experience frequent hospitalizations, providing a key opportunity to conduct SICs in the inpatient setting. The purpose of this study was to assess the feasibility of an inpatient SICP and describe completion of advance directives and SIC documentation after SICP implementation. Thi

Качественное изучение преференций в области физических упражнений среди испаноязычных взрослых с множественным склерозом.

Цель этого исследования состояла в том, чтобы определить компоненты идеальной программы тренировки для испаноязычных лиц с множественным склерозом (МС), культурными изменениями и способами распространения информации среди этой группы населения. В онлайновом режиме были проведены полуструктурированные собеседования с 27 взрослыми людьми, которые, как было установлено, являются испаноязычными. Для оценки необходимых и желаемых компонентов программы учений использовался подход, основанный на дедуктивном анализе содержания. Участники высказали предпочтения в отношении "что", "когда", "где" и "кто"

Patient Perspectives on Social and Identity Factors Affecting Multiple Myeloma Care: Barriers and Opportunities.

Patients living with multiple myeloma (MM) have a substantial disease burden and face multiple barriers to care. Building upon our previous research using mixed methods, this focus group research aimed to identify patients' priorities regarding specific social and identity-related needs, map these prioritized needs to the disease journey, and describe patient-generated ideas to improve patient support. Participants noted that patients with MM need a range of emotional, social, and financial support throughout the disease journey. They identified initial MM diagnosis and treatment adherence as

Evaluation by electronic patient-reported outcomes of cancer survivors' needs and the efficacy of inpatient cancer rehabilitation in different tumor entities.

ObjectiveWe investigated cancer survivors' health-related quality of life (HRQOL), specific deficiencies related to underlying disease or treatment, and benefits of rehabilitation in a large variety of cancer entities.Patients and methodsElectronic patient-reported outcomes were performed as clinical routine procedures. Cancer survivors underwent a 3-week multidisciplinary inpatient rehabilitation. Twenty-one different cancer entities were analyzed separately before (T0) and by the end (T1) of rehabilitation. HRQOL, symptoms, and functions were assessed with EORTC-QLQ-C30 questionnaire, psycho

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… Hence, early retirement and non-employment are common among cancer survivors [ 6 ]. Improved self-assessed capability of returning to work may help avoid unemployment. It might also be related to self-esteem and participation. … Early retirement and non-employment after breast cancer. Psychooncology. 2014;23:634–641. doi: 10.1002/pon.3459. 7. Reed SC, Bell JF, Whitney R, Lash R, Kim KK, Bold RJ, Joseph JG. Psychosocial outcomes in active treatment through survivorship. …