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Ключевые результаты мероприятий по профессиональной реабилитации лиц с множественным склерозом: Номинальное техническое исследование группы.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Мероприятия по профессиональной реабилитации лиц с множественным склерозом (МС) в целях удержания рабочих мест могут оказать позитивное воздействие на независимость человека и непосредственно повлиять на результаты в области здравоохранения и занятости. Вместе с тем оценка эффективности мероприятий в области ПР может быть сопряжена с трудностями в силу их весьма индивидуализированного характера и разнообразных потенциальных последствий для здоровья и занятости, которые могут быть затронуты. AIM: Определение наиболее важных результатов деятельности по сохранению рабочих м

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… For the last 2 years, I have been asked, “Have you thought about medical retirement?” And my answer is no, I will work as long as I can. Because I don't want to give up work. I want to get up. I want to have a purpose.’ Participant 1 ‘I mean, yeah, working as long as you can. … For the last 2 years, I have been asked, “Have you thought about medical retirement?” And my answer is no, I will work as long as I can. Because I don't want to give up work. I want to get up. I want to have a purpose.’ …

Patient perspectives on considerations, tradeoffs, and experiences with multiple myeloma treatment selection: a qualitative descriptive study.

BACKGROUND: Advances in multiple myeloma treatment and a proliferation of treatment options have resulted in improved survival rates and periods of symptom-free remission for many multiple myeloma patients. As a result, health-related quality of life (HRQoL) concerns related to myeloma treatments have become increasingly salient for this patient population and represent an important consideration guiding patients' treatment choices. To gain an understanding of patients' experiences with choosing myeloma therapies and explore the HRQoL concerns that are most important to them, we interviewed a

No blood transfusion for my own anaemia-tit for tat?

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… I am an anaesthetist and intensivist, currently in retirement. I was the former head of Operative Intensive Care of the University Hospital Regensburg, Germany. …

Deatary Inflammatory Score (DIS) и Life Score (LIS) «Влияние на многоразовый склероз» (LIS).

Фон/цели: Множественный склероз (MS) — иммунопосредованное демиелионирующее заболевание центральной нервной системы с изменяющимися уровнями воспаления и глиоза. Факторы питания и образа жизни могут влиять на развитие НР, а также способствовать воспалению. Целью нынешнего исследования является оценка взаимосвязи между пищевым и жизненным потенциалом и остротой множественных склерозов. Методы: Применялась схема перекрестного исследования. Сбор данных включал демографическую, неврологическую информацию и информацию о питании. На основе эталонного протокола были рассчитаны диетический воспламенит

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… It contributes to neurodegeneration, emerging as a leading cause of progressive disability and premature retirement among young adults [ 8 ]. … Similarly, a Brazilian cross-sectional study on a wide cohort of 15.000 employees described an overall healthier lifestyle in women, particularly after retirement. …

Racial and ethnic variations in caregiving-related physical, emotional, and financial strain during COVID-19 among those caring for adult cancer patients.

PurposeCancer caregiving is shown to be a burdensome experience in typical times. The purpose of this study was to describe cancer caregivers' emotional, physical, and financial strain during the COVID-19 pandemic and compared to preCOVID-19, and explore racial and ethnic variations in caregiver strain.MethodsWe conducted a cross-sectional online survey using Lucid, LLC, incorporating quotas for race, ethnicity, gender and age. Caregivers had to be adults living in the USA and currently providing unpaid care to an adult cancer patient (i.e., during COVID-19) and prior to the pandemic. We asses

Quality of life assessment & out-of-pocket expenditure in multiple myeloma: An observational study.

BACKGROUND & OBJECTIVES: Prognosis of patients with multiple myeloma (MM) has improved significantly in the past two decades. However, the symptoms burden is high at onset and treatment is generally prolonged with significant financial burden. This study was undertaken to assess the quality of life (QoL) and to analyse out-of-pocket expenditure (OOPE) incurred on MM patients being treated at a tertiary care cancer centre in north India. METHODS: This observational, cross-sectional study included 116 patients (aged >18 yr) of MM (both newly diagnosed and those with recurrent disease). For QoL

Symptom burden and health-related quality of life impacts of smoldering multiple myeloma: the patient perspective.

Abstract Background Smoldering multiple myeloma (SMM) is an early form of multiple myeloma (MM). SMM is typically considered asymptomatic, and research on how it affects health-related quality of life (HRQoL) is limited. This study assessed the symptoms and HRQoL of patients with SMM and those who progressed from SMM to MM and evaluated the content validity of two patient-reported outcome instruments (EORTC QLQ-C30 and nine items from the EORTC QLQ-MY20) for use in SMM clinical trials. To address these objectives, concept elicitation and cognitive interviews were conducted with SMM patients an

The diagnostic pathway of Parkinson's disease: a cross-sectional survey study of factors influencing patient dissatisfaction.

BackgroundThe diagnostic pathway of Parkinson's disease (PD) is often complicated. Experiences during this pathway can affect patients' satisfaction and their confidence and trust in healthcare providers. Although healthcare providers cannot influence the impact of the diagnosis, they can influence how patients experience the pathway. This study, therefore, aims to provide insight into PD patients' dissatisfaction with the diagnostic pathway and to describe the factors that influence it.MethodsWe carried out a cross-sectional survey study among 902 patient members of the Dutch Parkinson's Dise

Hypercalcemia of Malignancy: An Emergency Medicine Simulation.

Hypercalcemia is a poor prognostic factor associated with malignancy. The signs and symptoms of hypercalcemia that the patients present to the emergency department are vague and often overlap with the general symptoms of cancer itself or the adverse effects of the chemotherapy. Given that the development of hypercalcemia of malignancy can present with imminent danger to the patient and is a treatable condition, emergency physicians should know how to recognize and treat it. It also marks a time at which discussions regarding plans of care should be initiated with the patients. In this report,

Physical activity and ageing: The role of physiotherapy in promoting healthy ageing.

BackgroundThe global rise in the older population, especially in sub-Saharan Africa, has heightened the impact of non-communicable diseases (NCDs), responsible for 74% of global deaths and the leading cause for years lived with disability. Physical activity (PA) has proven to manage NCDs; however, 80% of older adults in sub-Saharan Africa engage in low-to-moderate PA levels.ObjectivesThis literature review explores current evidence on the effects of PA on ageing and NCDs in older people in sub-Saharan Africa. Insights gained will enable physiotherapists to refine their PA prescriptions, aligni

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… Loneliness is prevalent in ageing and some of the risk factors are (Somes 2021 ) as follows: death of loved one/spouse a lack of involvement with family (when children leave home) change of environment (e.g., relocation to an old age facility) retirement – a lack of social interaction with work colleagues … social stigma associated with ageing disorders (e.g., bladder/bowel incontinence) could lead to social embarrassment and increase the risk isolation decreased financial resources after retirement to facilitate socialisation. …

Оценка в реальном мире физиотерапевтических упражнений в процессе предварительной абилитации и реабилитации во время аутологической трансплантации стволовых клеток в миэломе: опыт работы в одном центре.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Имеются новые данные, свидетельствующие о роли упражнений в оптимизации функций, качестве жизни (QoL) и сокращении продолжительности пребывания в больнице, если они начались до пересадки аутологических стволовых клеток (ASCT). Проведенное на местном уровне экспериментальное исследование в области предабилитации и реабилитации пациентов миломы в ходе АОПП показало обнадеживающие результаты и было адаптировано к местным медицинским услугам. Цель настоящего доклада состоит в том, чтобы дать общее представление о недавно внедренной физиотерапевтической службе предварительной

Последние тенденции в области заболеваемости, выживания и лечения множественной миеломы в Финляндии - общенациональное когортное исследование.

Цель этого исследования состояла в том, чтобы определить распространенность и распространенность множественной миеломы (ММ) в Финляндии. 2015-2019, для характеристики взрослых пациентов, недавно диагностированных MM, и для контроля за их общим выживанием (OS) и схемами лечения до конца 2020. Мы почерпнули данные о стационарном и амбулаторном диагнозе, амбулаторном лечении и дате смерти из всеобъемлющих общенациональных регистров. Мы опознали 2037 пациенты с MM 2015-2019. В среднем годовой показатель общего числа случаев 8.8 и возрастная стандартная распространенность (мировой стандарт населени

Psychosocial distress in young adults surviving hematological malignancies: a pilot study.

PurposeSurvivors of cancer during young adulthood face multiple psychosocial challenges following treatment. This study explores psychosocial distress and unmet needs among young adult survivors treated of hematological malignancies.MethodsA total of 85 young adults aged between 18 and 39 years at time of diagnosis, were invited to join the survey after the completion of treatment with curative intent. Sociodemographic data and the need for advice were gathered with a self-report questionnaire. A set of standardized questionnaires for quality of life (EORTC QLQ-C30), psychosocial stressors (PH

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… Social issues Issues regarding rehabilitation (mean 4.78, SD 1.51) and early retirement (mean 4.35, SD 1.66) were of high interest, followed by information on acquiring a level of care (mean 3.7, SD 1.70). … Compared with healthy controls, AYA cancer survivors reported significantly higher levels of concern regarding retirement (25.5 vs 16.9%), standard of living (20.4 vs 12.9%), monthly bills (14.9 vs 10.3%), and housing costs (13.6 vs 8.9%) (Zheng et al. 2020 ). …

Patient-reported patterns of follow-up care in the 'Aftercare in Blood Cancer Survivors' (ABC) study.

BACKGROUND: Follow-up care provides long-term support for cancer survivors. Little is known about follow-up care in hematologic malignancies. METHODS: Our questionnaire-based study included blood cancer survivors diagnosed at the University Hospital of Essen before 2010, with a ≥ 3-year interval since the last intense treatment. The primary goal of the retrospective study was the identification and characterization of follow-up institutions. RESULTS: Of 2386 survivors meeting the inclusion criteria, 1551 (65.0%) consented to participate, with a follow-up duration > 10 years in 731. The unive

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… The most frequently suggested improvements were additional medical information (280/1262 survivors, 22.1%), support by a psychotherapist (224/1262, 17.7%), help with retirement issues (200/1262, 15.8%), and psychological support by a physician (137/1262, 10.9%). … 4/158 (2.5%) | 0.3417 Access to a patient advocacy group | 34/910 (3.7%) | 8/194 (4.1%) | 3/158 (1.9%) | 0.4655 Additional medical information | 193/910 (21.2%) | 52/194 (26.8%) | 35/158 (22.2%) | 0.2346 Help with employment issues | 58/910 (6.4%) | 12/194 (6.2%) | 11/158 (7.0%) | 0.9520 Help with retirement …

The contributions of family care-givers at end of life: A national post-bereavement census survey of cancer carers' hours of care and expenditures.

BackgroundFamily members provide vital care at end of life, enabling patients to remain at home. Such informal care contributes significantly to the economy while supporting patients' preferences and government policy. However, the value of care-givers' contributions is often underestimated or overlooked in evaluations. Without information on the activities and expenditures involved in informal care-giving, it is impossible to provide an accurate assessment of carers' contribution to end-of-life care.AimThe aim of this study was to investigate the contributions and expenditure of informal, fam

Perceived information provision and satisfaction among lymphoma and multiple myeloma survivors--results from a Dutch population-based study.

To improve posttreatment care for (long-term) lymphoma survivors in the Netherlands, survivorship clinics are being developed. As information provision is an important aspect of survivorship care, our aim was to evaluate the current perceived level of and satisfaction with information received by non-Hodgkin's lymphoma (NHL), Hodgkin's lymphoma (HL) and multiple myeloma (MM) survivors, and to identify associations with sociodemographic and clinical characteristics. The population-based Eindhoven Cancer Registry was used to select all patients diagnosed with NHL, HL and MM from 1999 to 2009. In

Longitudinal development and clinical predictors of financial toxicity among radiation oncology patients: final results of the SOCOFIN study.

PurposeFinancial toxicity (FT) associated with cancer and its treatment has become increasingly important. This study investigated factors associated with the development of FT during radiation therapy (RT). SOCOFIN was the first longitudinal prospective study to systematically evaluate FT in the context of RT.MethodsFinancial toxicity was measured with the Comprehensive Score for Financial Toxicity (COST-12) at RT initiation, completion, and at 3 months afterwards. Secondary endpoints included socioeconomic factors, health-related quality of life (EORTC QLQ-C30), depression (PHQ-9), coping me

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… Work-incapacitated patients (median 25) at baseline had significantly higher FT at 3 months after RT compared to retired patients (median 32), as shown in Fig. 6 . … 0.024 | −7.877 | −0.233 | −0.14 | 9.99e-13 | *** Age | −0.112 | 0.063 | −1.784 | −0.234 | 0.011 | 0.077 | – Gender (male vs. female) | −1.871 | 1.133 | −1.651 | −4.091 | 0.35 | 0.101 | – No systemic therapy or hormone therapy (vs. systemic therapy) | 1.867 | 1.234 | 1.513 | −0.552 | 4.285 | 0.133 | – Retirement …

Perspectives of patients, partners, primary and hospital-based health care professionals on living with advanced cancer and systemic treatment.

PurposeAn emerging group of patients lives longer with advanced cancer while receiving systemic treatment. This study aimed to investigate psychosocial aspects of living longer with advanced cancer, and experiences with psychosocial care, from the perspectives of patients, partners, and health care professionals (HCPs).MethodsFrom May to December 2020, participants were purposively selected. In-depth, semi-structured interviews were conducted by video or phone call, containing open questions regarding psychosocial aspects and psychosocial care in oncology. The data was analysed following thema

Missed Opportunities in Geriatric Oncology Research.

The field of geriatric oncology has made significant progress in recent decades, but there are still missed opportunities in important areas of research. One issue is the underrepresentation of older patients, especially those aged 75 years and older, in clinical trials. This has resulted in a lack of high-quality data for the care of this population, and the American Society of Clinical Oncology has called for an increase in the evidence base for older patients with cancer. The second missed opportunity is the chance to gather important knowledge from older patients participating in clinical

Стрессивая симметрия: паралич двустороннего Белла, потенциально вызванный экстремальным стрессом.

Лица с нервыми (FNP) идиопатического происхождения обычно называются параличом Белла. Двусторонний ФНП представляет собой исключительно редкую подгруппу всех дел, связанных с параличом Белла. Она может проявляться либо синхронно, либо последовательно, с одной стороны, с другой стороны, с последующим участием противоположной стороны в течение первых 30 дней с момента возникновения симптома. Обычные этиологии ФНП охватывают такие инфекции, как инфекционный мононуклеоз, грипп, болезнь лайма и менингит. Неинфекционные причины включают в себя новообразования, множественный склероз и синдром Гильен-