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Comparative effects of diazinon and malathion in Najdi sheep.

The comparative effects of diazinon and malathion on Najdi sheep were described in sheep allotted as untreated controls, diazinon-treated at 25 mg/kg/d or 50 mg/kg/d, and malathion-treated at 25 mg/kg/d or 50 mg/kg/d. Although serum cholinesterase (ChE) activity was reduced, neither significant clinical signs nor severe pathological changes were produced in sheep dosed orally with 25 or 50 mg diazinon/kg/d for 21 d. Both oral dose levels of malathion were lethal to sheep between 1 and 6 d and caused, prior to death, hyperexcitability, tremors, clonic convulsions, salivation, nasal discharge, i…

Pyrethroids, nerve poisons: how their risks to human health should be assessed.

The extensive worldwide efforts of structural modification of natural pyrethrins for better performances have resulted in successful develop … nounced repetitive activity characterized grossly by tremor, hypersensitivity, choleoathetosis, and salivation. In addition, so-called cyano-pyrethroids cause transient skin paresthesia in workers. With regard to tumorigenicity, mutagenicity, teratogenicity and developmental toxicity, no significant findings have been reported. Pyrethroids are eliminated fro …

Early (preweanling) recognition of alcohol's orosensory cues resulting from acute ethanol intoxication.

Three experiments were conducted in order to analyze the possibility that during acute alcohol intoxication, preweanling rats process ethano … takes place during acute ethanol intoxication probably due to ethanol elimination via respiration, salivation, and/or hematogenic olfaction processes.

Transdermal scopolamine: a review of its effects upon motion sickness, psychological performance, and physiological functioning.

Scopolamine is the most effective single drug for the prophylaxis and treatment of motion sickness. However, oral or injected scopolamine di … ovided by oral scopolamine or dimenhydrinate. Its autonomic nervous system effects comprise reduced salivation, bradycardia, and blurred vision due to reduced visual accommodation. The visual problems increase following repeated patch applications, with hypermetropic ("long sighted") individuals particularly at risk. Central nervous system effects comprise r …

Carbamate and organophosphate poisoning in early childhood.

Twenty-five infants and young children intoxicated by carbamate and organophosphorus compounds are described. Presenting signs and symptoms in children differed from those described in adults and were mainly related to severe CNS depression, coma and stupor, dyspnea, and flaccidity. Other clinical signs such as miosis, excessive salivation and tearing, sweaty, cold skin, and gastrointestinal symptoms were less frequent, while fasciculations and bradycardia were quite uncommon on arrival. Only two patients presented with all typical signs of organophosphate poisoning as described in adults. Sig…

Mandibular and parotid salivary excretion of procainamide and N-acetylprocainamide after intravenous administration of procainamide to rats.

Flow rate, protein level and pH of mandibular and parotid saliva samples in rats were almost stabilized 2 h after induction of salivation with pilocarpine (9.0 mg h-1 kg-1). Salivary excretion profiles of procainamide, 50 mg kg-1 i.v., and its metabolite N-acetylprocainamide (NAPA) were then investigated. Plasma and salivary procainamide levels declined bi-exponentially with time almost in parallel. Salivary procainamide levels (Y) from both types of gland were correlated with the plasma level (X) over a wide concentration range [Y = 0.108X + 1.96 (r = 0.795) for mandibular and Y = 0.917X (r =…

Natural history of bell's palsy: the salivary flow test and other prognostic indicators.

Fifty-one patients with Bell's palsy were evaluated within two days of onset and followed for six months without surgical intervention or ef … her tests did not become altered until 3 to 14 days after onset. In patients with Bell's palsy, the salivation test seems to be the only method capable of predicting denervation before it begins; therefore, it should be ideal for selecting patients for appropriate treatment.

Lyme disease transmission by severely impaired ticks.

It has been demonstrated that impairing protein synthesis using drugs targeted against tRNA amino acid synthetases presents a promising strategy for the treatment of a wide variety of parasitic diseases, including malaria and toxoplasmosis. This is the first study evaluating tRNA synthetases as potential drug targets in ticks. RNAi knock-down of all tested tRNA synthetases had a strong deleterious phenotype on Ixodes ricinus feeding. Our data indicate that tRNA synthetases represent attractive, anti-tick targets warranting the design of selective inhibitors. Further, we tested whether these se

Ethnoveterinary medicine of the Shervaroy Hills of Eastern Ghats, India as alternative medicine for animals.

The Eastern Ghats of India is well known for its wealth of natural vegetation and Shervaroy is a major hill range of the Eastern Ghats of Ta … o 16 families are used to cure various diseases such as mastitis, enteritis, arthritis, stomatitis, salivation from the mouth, wounding, and conjunctivitis in animals. It has been observed that the traditional knowledge of ethnoveterinary medicine is now confined only among the surviving older people and a few practitioners in the tribal communities of the S …

The effects of a hot drink on nasal airflow and symptoms of common cold and flu.

Hot drinks are a common treatment for common cold and flu but there are no studies reported in the scientific and clinical literature on thi … . The effects of the drinks are discussed in terms of a placebo effect and physiological effects on salivation and airway secretions. In conclusion the results support the folklore that a hot tasty drink is a beneficial treatment for relief of most symptoms of common cold and flu.

Leukoplakia: A correlative study of clinical picture and cytohistopathology.

Leukoplakia means a " White Patch", and is defined as a white patch or plaque on the mu-cosa that cannot be rubbed off and is not ascribable to any other condition(Fig. 1). Many patients come to the O.P.D. with presentation of white patch, ulcer, excessive salivation, trismus, increased sensitivity to chilies and burning sensation, dysphagia, otalgia and ultimately growth. Advanced countries have attained sophistication in oncopathy (like tumor marker, tumor antibodies). But we are still in search of an efficient screening method by which the cytologist can point accurately towards the nature …

A neurokinin-1 receptor antagonist reduced hypersalivation and gastric contractility related to emesis in dogs.

The roles of tachykinin neurokinin-1 (NK1) receptors in the induction of fictive retching, hypersalivation, and gastric responses associated with emesis induced by abdominal vagal stimulation were studied in paralyzed, decerebrated dogs. Vagal stimulation induced gradual increases in salivary secretion and activity of the parasympathetic postganglionic fibers to the submandibular gland, relaxation of the gastric corpus and antrum, and fictive retching. However, hypersalivation and increased nerve activity were suppressed and antral contractility was enhanced during fictive retching. An NK1 rec…

The laryngeal mask airway--clinical experience.

The laryngeal mask airway (LMA), a new type of airway, when it is inserted blindly into the hypopharynx forms a seal around the larynx and a … 2 patients. Insertion failure was seen in 2 patients respectively due to small mouth and excessive salivation. The placement of LMA does not require laryngoscopy and there is no fear of misplacement in the esophagus. It becomes obvious that the LMA would substantially gain a place in the armamentarium in anesthesia and we think that its use would be of inte …

[On the cholinolytic activity of pramiverine].

Pharmacological experiments with the spasmolytic 4,4-diphenyl-N-isopropyl-cyclohexylamine hydrochloride (pramiverine, Sistalgin) are reporte … in the guinea pig; hypotensive effect after acetylcholine administration in rabbits, cats and dogs; salivation after pilocarpine administration in rabbits; tremorine test in rats. The gastric secretion in the Shay rat and the gastrointestinal passage were reduced or inhibited by pramiverine. The test substance was also active on oral application.

Diaspora of oral maxillofacial pathology and dermatopathology-A review.

The oral cavity is an important diagnostic window because it frequently reflects dermatological, infectious, autoimmune, genetic and systemic disorders. Oral lesions may precede cutaneous or systemic manifestations in several conditions, including lichen planus, pemphigus vulgaris, viral infections, connective tissue disorders, vasculitic syndromes and immunodeficiency-associated diseases. The clinical appearance of oral lesions is often modified by salivation, mastication, microbial colonization, trauma and the thin nature of non-keratinized mucosa. Therefore, lesions that appear as vesicles …

Solid type primary intraosseous squamous cell carcinoma in a long hair cat.

BACKGROUND: Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare and aggressive malignancy that originates within the bone, reported in both humans and animals. While squamous cell carcinoma is the most common oral tumor in cats, PIOSCC is an uncommon variant with distinct clinical and pathological features. CASE DESCRIPTION: A 10-year-old spayed female domestic longhair cat presented with a progressively enlarging mass at the rostral mandible. Over 6 weeks, the cat exhibited clinical signs including inappetence, excessive salivation, and pain. Diagnostic evaluations comprised hema…

Strategy to kill two birds with one stone: High internal phase Pickering emulsions to modulate 3D printed pork texture as a dysphagia diet.

This study proposes a kill two birds with one stone strategy to improve the health and safety of pork with high internal phase Pickering emu … cooking loss of pork (from 30.8 % to 1.9 %), which is suitable for dysphagic patients with reduced salivation. HIPPEs adjusts the properties of pork gel by filling and winding gel networks. These results provide new ideas for the development of special formula foods.

Москиты из Европы способны передать вирус снежного тумана.

Вирус снежинки (SSHV) — зоонотический вирус, распространяющийся через артропод (arbovirus), вращающийся в более холодных районах Северного полушария. SSHV поддерживается в энзоотическом цикле между мелкими млекопитающими и комарами, что, по всей вероятности, соответствует роду эдес и кулисета. Симптомы SSHV-инфекции человека могут варьироваться от асимптоматических до тяжелых нейроинвазивных заболеваний. Исследования по проблеме передачи SSHV ограничены, и нет никакой информации о том, могут ли комары рода Culex передавать SSHV. Поэтому мы изучили шесть видов комаров с помощью анализа слюны на

Совпадение в аннотации оригинала
Snowshoe hare virus (SSHV) is a zoonotic arthropod-borne virus (arbovirus) circulating in colder areas of the Northern Hemisphere. SSHV is m … s of the genus Culex are able to transmit SSHV. Therefore, we investigated six mosquito species via salivation assay for their vector competence. We demonstrated that SSHV can be transmitted by the abundant European Culex species Cx. pipiens biotype pipiens, Cx. pipiens biotype molestus, and Cx. torrentium with low transmission efficiency between 3.33% and 6 …

Toxic effects seen in a herd of beef cattle following exposure to ash residues contaminated by lead and mercury.

Lead poisoning was diagnosed in three cattle along with increased mercury levels in the liver and kidney tissues of two of these animals. The clinical signs were different in each case and included salivation, anorexia, delayed menace response, delayed withdrawal reflex, head pressing, localized muscle fasciculation, reduced tongue tone, ataxia, rumen atony and seizures. Blood lead concentration was increased in all three cases to 0.76, 0.37 and 0.454ppm. Post mortem changes characteristic of lead poisoning were only recognized in one case and included cerebro-cortical oedema, cortical neurona…

Xerostomia, xerophthalmia, and plasmacytic infiltrates of the salivary glands (Sjögren's-like syndrome) in a cat.

A 2.5-year-old domestic shorthair cat was evaluated because of dysphagia and weight loss of 4 weeks' duration. MIld blepharospasm and conjunctival hyperemia were evident in both eyes, oral mucous membranes were tacky on palpation, and salivary glands were enlarged. Results of a Schirmer tear test were 0 mm/min for both eyes. Administration of atropine did not cause salivation or caused secretion fo thick rope-like saliva. Examination of biopsy specimens of salivary glands revealed a plasmacytic infiltrate. Sjögren's syndrome (SS) was diagnosed. Oral administration of prednisone was instituted …