Результаты поиска

Menstrual pattern and abnormalities in the high school girls of Dharan: a cross sectional study in two boarding schools.

Puberty is the biological transition between the immature and adult reproductive function. This study has been carried out to find out the menstrual pattern, and awareness of the abnormalities in menstrual pattern among school going pubertal age group girls in Dharan. It has been carried out with the aim to follow it with school health education. Cross sectional study was done in 96 girls of two different school of Dharan of the age group ranging from 11 years to 17 years. The median age of menarche was 12 years. There were 6.9% cases of oligomennorhea and 10.0% of hypomenorhea. Menorrhagia wa

Measles outbreak in a vaccinated population in Dhankutta.

A measles outbreak occurred in Dhankutta town in year 2056 Falgun to 2057 Baishak (3 months). A total of 130 cases were registered at the Dhankutta District Hospital. A large proportion of the cases had severe disease with complications and were admitted at the hospital. None of the patients registered at the hospital died. Interestingly, 50.0% of cases were in higher age group (10 years and above) which is an unusual trend in developing countries. All the cases gave history of measles vaccination, which points towards the need for investigation of vaccine efficacy and cold chain efficiency.

A scoping review of the literature on the application and usefulness of the Problem Management Plus (PM+) intervention around the world.

BackgroundGiven the high rates of common mental disorders and limited resources, task-shifting psychosocial interventions are needed to provide adequate care. One such intervention developed by the World Health Organization is Problem Management Plus (PM+).AimsThis review maps the evidence regarding the extent of application and usefulness of the PM+ intervention, i.e. adaptability, feasibility, effectiveness and scalability, since it was introduced in 2016.MethodWe conducted a scoping review of seven literature databases and grey literature from January 2015 to February 2024, to identify peer

Совпадение в полном тексте источника
… Effectiveness of group problem management plus, a brief psychological intervention for adults affected by humanitarian disasters in Nepal: a cluster randomized controlled trial . … Feasibility of group problem management plus (PM+) to improve mental health and functioning of adults in earthquake-affected communities in Nepal . …

Variations in Commencement of Median Nerve.

BACKGROUND: The median nerve, normally formed by two roots from the medial and lateral cords in relation to the axillary artery, but variations in its roots and unusual communications with other nerves are common. These anatomical differences can compromise anesthesia and are vulnerable to iatrogenic injury during surgical procedures of the upper limb. This study was conducted to determine the prevalence of such anatomical variations in axillary and arm regions. METHODS: A descriptive cross sectional study was conducted on 66 upper limbs from embalmed adult human cadavers, selected using a co

Allergy to Ringer's Lactate - Uncommon Cause of Anaphylaxis during Intraoperative Period: A Case Report.

Perioperative anaphylaxis is a rare but potentially fatal event, with an incidence ranging from 1:300 to 1:20,000 surgeries and a mortality rate of 3-9%. Its intraoperative occurrence is diagnostically challenging due to patient sedation and overlapping drug effects. Crystalloids like Ringer's Lactate are rarely implicated. A 27-year-old American Society of Anesthesiologists grade I female undergoing mastoidectomy developed intraoperative hypotension, tachycardia, and generalized erythema after induction with standard anesthetics and Ringer's Lactate infusion. Anaphylaxis was suspected, and Ri

Changes in Corneal Curvature and Astigmatism After Phacoemulsification Surgery.

BACKGROUND: This study aimed to investigate the relationship between anterior corneal curvature and astigmatism before and after phacoemulsification surgery. METHODS: A total of 90 eyes from 90 participants who underwent phacoemulsification with a 3.0 mm superior-temporal clear corneal incision were included in this longitudinal study. Each participant underwent a comprehensive ocular examination, including refraction and keratometry readings (k-readings) obtained using an automated keratometer on the IOL Master. Examinations were conducted preoperatively, on the first postoperative day, at o

Effectiveness of Intranasal Dexmedetomidine for Sedation in Children.

BACKGROUND: Preoperative sedation in children is necessary as it is a common source of distress, potentially leading to difficult induction. Intranasal dexmedetomidine bypasses hepatic metabolism and has good availability. It is non invasive, easy with minimal respiratory depression. This study aimed to observe safety, efficacy, sedation level and parental separation score following a fixed dose of 1.5 mcg/kg Methods: A cross sectional study design was conducted among 43 children posted for elective surgeries. After informed consent and assent were obtained, intranasal DEX 1.5mcg/kg was admini

Long-level Intramedullary Spinal Cord Tumor: A Case Series.

Spinal cord tumors, though uncommon, pose significant challenges due to their potential for neurological disability and mortality. Intramedullary spinal cord tumors, particularly Long-level intramedullary spinal cord tumors, present challenging clinical scenarios. Contrast-enhanced Magnetic resonance imaging remains pivotal for radiological evaluation and surgical planning. Notably, aggressive resection is advocated to enhance prognosis, with meticulous attention to preserving neurological function. Advancements in spinal surgery techniques, coupled with intraoperative monitoring, offer promis

Current Status and Future Potential of Machine Learning in Diagnostic Imaging of Endometriosis : A Literature Review.

The presence of endometrial tissue outside the uterus is a defining characteristic of endometriosis, a chronic systemic illness that affects women of childbearing age. Despite its enigmatic nature, laparoscopy remains the gold standard for diagnosis, while noninvasive methods such as transvaginal ultrasonography and magnetic resonance imaging are commonly used to aid in preoperative planning. In healthcare, AI has emerged as a game-changing innovation, enhancing patient outcomes, reducing costs, and revolutionizing healthcare delivery, particularly in diagnostic radiology. Images can be analyz

Central Corneal Thickness and Intraocular Pressure Measured with Goldmann Applanation Tonometer among Patients with Normal Intraocular Pressure.

BACKGROUND: Intraocular pressure measurement is one of the important and commonly performed examination in Ophthalmology. Goldmann applanation tonometer has been gold standard for measurement of Intraocular pressure. Intraocular pressure measurement is known to be affected by Central corneal thickness. It has been stated that thinner cornea leads to false low Intraocular pressure while thicker cornea leads to false high Intraocular pressure interpretations. METHODS: A total of 920 patients of forty and above years with no any anterior segment pathology like corneal diseases, corneal oedema an

Rare presentation of Eccrine Porocarcinoma.

Eccrine porocarcinoma is a tumor of the sweat gland that mostly develops from an existing benign eccrine poroma. It is a rare cutaneous malignancy with a high risk of metastasis and recurrence. Known to affect the elderly population in general with no gender discrepancy, it presents as an ulcerative mass commonly in the trunk or head/neck region. Definitive diagnosis is made by histopathological findings of peculiar pleomorphic cells with nuclear hyperchromasia and mitotic activity, surrounded by ductal lumen. The standard treatment is complete surgical excision with appropriate surgical margi

Coping Strategies among Patients with Dissociative Disorder: An Observational Study.

INTRODUCTION: Various factors contribute to the development of dissociative disorders. The ability to cope with different stressful events is key to symptom manifestations in this disorder. This study aims to explore various stressors and coping strategies in patients with dissociative disorder and the relationship between coping strategies with stressors and clinicodemographic characteristics. METHODS: This was an observational cross-section study which evaluated patients with dissociative disorder presenting at the Department of Psychiatry in a tertiary care teaching hospital for 6 months (

Vaginal Neoplasm in a Breast Cancer Survivor.

According to GLOBOCAN 2022 data, Carcinoma breast is the second most common malignancy worldwide after lung and ranks 4th in mortality worldwide. Breast cancer can metastasize to various organs. The incidence of vaginal metastasis in carcinoma breast is 1-2%. Here we present a patient with post menopausal bleeding with vaginal mass. She had a history of Triple negative carcinoma left breast 3 years back, treated by Modified Radical Mastectomy followed by chemo radiotherapy. Vaginal biopsy was suggestive of a metastatic carcinoma breast. MRI and PET CT showed isolated vaginal growth. Due to poo

Ultrasound-guided Hydrostatic Reduction of Acute Intussusception in Children at a Tertiary Care Center: An Observational Study.

INTRODUCTION: Intussusception is common cause of acute emergency responsible for bowel obstruction in infants and toddlers with peak age of incidence between 6-9 months. Ultrasound is imaging modality of choice for diagnosis of intussusception and ultrasound guided hydrostatic enema reduction is standard, nonsurgical, internationally preferred treatment modality for uncomplicated pediatric intussusceptions. This study was aimed to find the outcome of the procedure. METHODS: An observational cross-section was carried in a tertiary care center in children presenting with intussusception. Ultras

Spontaneous Entero-Cutaneous Fistula due to Femoral Hernia: A Case Report.

An enterocutaneous fistula is an aberrant connection between the intra-abdominal gastrointestinal tract and skin/wound. Spontaneous enterocutaneous fistula secondary to femoral hernia is extremely rare but may be life-threatening because of sepsis, malnutrition and stuid-electrolyte imbalance. We report an 83-year-old woman who presented with a short history of irreducible right groin swelling associated with feculent discharge. Contrast-enhanced computed tomography revealed a perforated distal ileal loop within a right femoral hernia, forming an enterocutaneous fistula. She underwent emergenc

Oral Ethanol for Methanol Poisoning: A Case Report.

Methanol poisoning usually occurs due to accidental ingestion of distilling and fermenting errors or beverage contamination. The typical presentation includes visual disturbances with severe metabolic acidosis and neurological damage. A 32-year-old male presented with blurring of vision for 2 days, with a history of local alcohol consumption 2 days prior, with severe metabolic acidosis on arterial blood gas analysis, and was clinically diagnosed and treated as methanol poisoning in the absence of a serum methanol assay. He responded favorably to the treatment with timely oral ethanol via Nasog

Postpartum Cavernous Sinus Thrombosis Associated with Eclampsia and Gestational Diabetes Mellitus: A Case Report.

Pregnancy is the pro-thrombotic state. The objective of this report is to highlight the rare occurance of postpartum cavernous sinus thrombosis associated with eclampsia and gestational diabetes mellitus, emphasizing its clinical presentation. A 25-year-old Muslim female came with the complaint of headache,post auricular and right parietal region on 8th day post-partum. She had a history of postpartum eclampsia and Gestational Diabetes Mellitus for which she was treated with magnesium sulfate and oral hypoglycaemic agents respectively. MRV showed a filling defect in right transverse sinus, sig

Klippel-Trenaunay Syndrome in the Distal Part of the Unilateral Upper Limb and Venous Deficiency: A Case Report.

Klippel-Trenaunay Syndrome is a rare congenital disorder characterized by a triad of symptoms-capillary malformations, venous abnormalities, and hypertrophy of bones and soft tissues. The syndrome often presents with port wine stains, varicose veins, and limb hypertrophy, which can lead to significant complications such as venous thromboembolism and bleeding. We present a case of a 13 ' year female, with erythema in left upper limb and shoulder since birth.. An effective treatment method was employed, which incorporated a multidisciplinary team of experts specialized in various fields of derma

Axenfeld Rieger Syndrome Presenting with Open Angle Glaucoma in an Adult Patient: A Case Report.

Axenfeld Rieger Syndrome is autosomal dominant genetic condition, which can present with various ocular and non-ocular findings. Anterior segment dysgenesis is the most common ocular finding leading to glaucoma. Non-ocular findings include craniofacial abnormalities, cardiac, dental as well as neurological problems. Mutations in PITX2 and FOXC1 genes have been associated with this condition. FOXC1 mutation causes more ocular findings where as PITX2 mutation has been linked with ocular as well as craniofacial abnormalities. Racial or gender predilection has not been suggested by any literature.