Результаты поиска

The Recently Discovered Bokeloh Bat Lyssavirus: Insights Into Its Genetic Heterogeneity and Spatial Distribution in Europe and the Population Genetics of Its Primary Host.

In 2010, a novel lyssavirus named Bokeloh bat lyssavirus (BBLV) was isolated from a Natterer's bat (Myotis nattereri) in Germany. Two further viruses were isolated in the same country and in France in recent years, all from the same bat species and all found in moribund or dead bats. Here we report the description and the full-length genome sequence of five additional BBLV isolates from Germany (n=4) and France (n=1). Interestingly, all of them were isolated from the Natterer's bat, except one from Germany, which was found in a common Pipistrelle bat (Pipistrellus pipistrellus), a widespread a…

Influenza and pneumococcal vaccination in patients with rheumatoid arthritis in comparison with age- and sex-matched controls: results of a claims data analysis.

The aim of this study was to assess the vaccination status for influenza and pneumonia and the prevalence of hospitalised pneumonia in rheumatoid arthritis (RA) patients and population controls in Germany. Members of a large statutory health insurance fund in Germany who were continuously insured between 2009 and 2013 and had a diagnosis of RA in 2013 were age and sex matched 1:5 to members without RA. Pneumococcal and influenza vaccinations were evaluated with regard to age, sex and region of residence. Logistic regression models were used to determine predictors for influenza vaccination in …

[Climate changes and emerging diseases. What new infectious diseases and health problem can be expected?].

Increasing temperatures, but also other climatic factors, will have an impact on human health. Apart from the direct consequences of extreme weather conditions (e.g., heat-related fatalities), indirect health consequences in the long-term are also of great importance. In addition to a likely increase in allergic diseases and additional complications in the course of cardiovascular and respiratory diseases, infectious diseases are of particular interest. In Germany, endemic pathogens, such as hantavirus (with its reservoir in small rodents), tick-borne pathogens (Borrelia burgdorferi, tick-born…

Public Interest in Knee Pain and Knee Replacement during the SARS-CoV-2 Pandemic in Western Europe.

Due to the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pandemic, a large number of elective knee replacement procedures had to be postponed in both early and late 2020 in most western countries including Germany and the UK. It is unknown how public interest and demand for total knee arthroplasties was affected. Public interest in knee pain, knee osteoarthritis and knee arthroplasty in Germany and the UK was investigated using Google Trend Analysis. In addition, we monitored for changes in patient composition in our outpatient department. As of early March in Germany and o…

Pharmacological treatment of inhalation injury after nuclear or radiological incidents: The Chinese and German approach.

Inhalation injury is often associated with burns and significantly increases morbidity and mortality. The main toxic components of fire smoke are carbon monoxide, hydrogen cyanide, and irritants. In the case of an incident at a nuclear power plant or recycling facility associated with fire, smoke may also contain radioactive material. Medical treatments may vary in different countries, and in this paper, we discuss the similarities and differences in the treatments between China and Germany. Carbon monoxide poisoning is treated by 100% oxygen administration and, if available, hyperbaric oxygen…

German multicenter study group for adult ALL (GMALL): recruitment in comparison to ALL incidence and its impact on study results.

Due to eligibility criteria not all patients with the disease under investigation can be recruited for therapeutic studies. Thus, the external validity of study results cannot per se be taken for granted. The representativity of the admitted patients is the most relevant determinant for external validity and has to be assessed. As an example we examined the representativity of the patients recruited for the German multicenter study group for adult acute lymphoblastic leukemia (ALL) (GMALL). Lacking nationwide ALL incidence figures available in Germany, a methodology was developed to estimate i…

Rates of antimicrobial resistance among common bacterial pathogens causing respiratory, blood, urine, and skin and soft tissue infections in pediatric patients.

Antimicrobial resistance patterns among the principal bacterial pathogens from infections of the respiratory tract, blood, skin and soft tissue, and urinary tract of pediatric patients from the USA, Canada, Germany, France, and Italy were studied using the The Surveillance Network (TSN) database. Among Streptococcus pneumoniae isolates from respiratory tract infections, the prevalence of high-level penicillin resistance (MIC>/=2 microg/ml) ranged from 1.1 (Italy) to 36.2% (USA); erythromycin resistance was higher, ranging from 13.4 (Germany) to 63.8% (France). The prevalence of beta-lactamase-…

[Organization and role of the German public health service].

The article describes the organization and role of the public health service in Germany. Health is not a federal but a state issue; sta-te health regulations are subject to state legislation. The role of the public health service may therefore differ among the federal sta-tes of Germany. In recent years there ha-ve been considerable changes in the main features of the role of the public health ser-vice. Prevention and health reporting have become top issues, as well as hygiene, control of epidemics, medical certificates, and physical and dental examinations for schoolchildren. The public healt…

[Screening for toxoplasmosis in pregnancy: more harm than good].

Using data from international literature makes it possible to calculate for Germany benefit and harm of a screening for toxoplasmosis in pregnancy. On the basis of these data harm of such a screening is much greater than benefit. Taking the reported number of congenital toxoplasmosis in Germany as the base for such a calculation of harm and benefit makes the ratio of benefit and harm even worse.

How are nurses' individual and their colleagues' diversity factors associated with their cooperation behaviors in teams? - Results of an online factorial survey.

BACKGROUND: Diversity within nursing teams in Germany increases due to staff shortages, nurse migration and the current academization of the profession. Little is known about how nurse’s own diversity factors and those of team members impact nurse’s perception and behavior in team situations. This study examines if and how nurses differentiate in the assessment of their colleagues’ nursing abilities in basic care, i.e. patient’s personal hygiene and treatment care, i.e. the set-up of an infusion, as well as their willingness to swap shifts with colleagues. METHODS: A quasi-experimental, cross-…

Live Cell Therapy as Potential Risk Factor for Q Fever.

During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans. Q fever developed in 7 LCT recipients from Canada, Germany, and the United States.

Pulmonary Artery Banding for Children With Dilated Cardiomyopathy: US Experience.

Pulmonary artery band placement is a recently described therapeutic strategy for dilated cardiomyopathy with preserved right ventricular function, originally reported from Germany.1 We present the results of the multicenter retrospective study of pulmonary artery band experience in the United States, with comparison to the German experience. Five centers contributed a total 14 patients (median age 5 months, interquartile range 3.5-10). Mechanical ventilation was required in 9/12 (75%) patients and inotropes were used in 13/14 (93%) patients preoperatively. Ultimately, 4 (29%) patients experien…

[Psychological symptoms after immigration: a comparison of various groups of immigrants in Berlin].

In a postal questionnaire we examined three samples of persons seven and a half months after their migration to Berlin: 1. 512 people having left East Germany, 2. 90 Germans who had left Poland, and 3. 283 people who lived in western parts of Germany before. The present study was to investigate social integration and psychic complaints in these groups. In general, all groups reported increased frequencies of unspecific symptoms like inner restlessness, irritability, nervousness, rumination, and sleeplessness. In people from the GDR symptoms decreased significantly during the first seven months…

Early vaccine advocacy: Medals honoring Edward Jenner issued during the 19th century.

The results from the first vaccination experiments published by Edward Jenner in 1798 were widely disseminated and consequently Jennerian vaccination was rapidly introduced in Europe and elsewhere. One of the reasons for the rapid spread of vaccination was that Jenner championed the procedure as a public health tool and not just as a mean to achieve individual protection. Vaccination was promoted by the highest levels of government in Germany where the vaccine was introduced in 1799 and also in France, where the vaccine arrived in 1800. Medals were used to promote vaccination both rewarding pa…

Lymphocytic Choriomeningitis Virus Seroprevalence in a Cohort of German Forestry Workers.

Forestry workers are exposed, through their occupation, to a variety of zoonotic pathogens. Lymphocytic choriomeningitis virus (LCMV) is a zoonotic agent typically transmitted through the excreta of infected rodents. Current knowledge concerning the prevalence of LCMV in wild house mice (Mus musculus) in Germany is limited, with the majority of data coming from studies during the 1960s and 1970s and only from the western and southern federal states. In this study, blood samples from 563 forestry workers, collected in 2008 from ten forestry offices in Brandenburg, Germany, were screened for LCM…

Genotyping of measles virus isolates from central Europe and Russia.

Sequence analysis of 285 nucleotides located on the variable part of the N gene was undertaken on measles virus (MV) samples collected from acutely infected patients in Germany, the Czech Republic, Denmark, Poland, and Russia. Two distinct genotypes (C2 and D6) have circulated in Germany between 1993 and 1996. Isolates of genotype C2 were related to strains reported in Germany before 1993. This genotype was also found in the Czech Republic in 1992 and in Denmark in 1997. The occurrence of genotype D6 in Germany is described below for the first time. In 1998, this genotype was identified in Pol…

Показатели иммунизации при поступлении в школу в 2012 году.

В последние годы в Германии были зарегистрированы столь низкие показатели иммунизации по некоторым заболеваниям, включая корь, что имели место эндемические вспышки. Для выявления недостаточно иммунизированных районов необходим подробный географический анализ показателей иммунизации. МЕТОДЫ: Мы рассмотрели этот вопрос с помощью региональных и местных данных, полученных в ходе вступительных экзаменов в школы, которые были предоставлены нам департаментами здравоохранения федеральных штатов Германии. Эти данные представлены как в табличной форме, так и с помощью географической информационной систе

Совпадение в аннотации оригинала
BACKGROUND: The immunization rates for some diseases, including measles, were so low in Germany in recent years that endemic outbreaks occurred. A finely detailed geographic analysis of immunization rates is necessary for the identification of under-immunized areas. METHODS: We addressed this question with the aid of regional and local data from school entr…

[Lemierre and Sohier's mission (3-13 January 1942)].

During the winter of 1941-42, an epidemic of louse borne typhus fever spread over prisoners of war camps in Germany. As the protector of her own captive citizens, France sent a mission to Germany composed of Professor Lemierre and Major Sohier in order to inquire about the German's actions to protect the French prisoners from this disease.

Advanced Techniques for Bone Restoration and Immediate Loading after Implant Failure: A Case Report.

The objective of this study was to report a clinical case of dental implant failure with significant bone loss that was treated using reconstructive surgical techniques. We present a 58-year-old man with a history of implant surgery and implant failure on the mandible. Data collected using cone beam computed tomography (CBCT) and intraoral scans were exported into Exoplan (exocad GmbH, Darmstadt, Germany), from which a standard tessellation file was obtained. To create a customized mandible mesh design, DentalCAD 3.0 Galway software (exocad GmbH, Darmstadt, Germany) was used. Based on guided b…