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Role of radiosurgical thalamotomy in the management for essential tremor: evidence from an international multi-institutional study.

INTRODUCTION: Essential tremor is a common movement disorder that can cause substantial functional disability when symptoms become medically … an improvement of 7.46 points (p < 0.001). Significant improvement was also observed across tremor, writing, drawing, and drinking sub scores (all p < 0.001). On multivariable analysis, a maximum lesion dose ≥ 140 Gy was independently associated with greater odds of clinical benefit (OR 3.44, p = 0.019). CONCLUSION: In this multi-institutional cohort, SR …

Management of anticoagulation in patients with heparin-induced thrombocytopenia requiring cardiac surgery with cardiopulmonary bypass: guidance from the ISTH SSC on Perioperative and Critical Care Haemostasis and Thrombosis.

Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse drug reaction characterized by thrombocytopenia and a high risk of thrombosis. Patients with HIT and a need for cardiac surgery with cardiopulmonary bypass represent a challenging group, as anticoagulation with unfractionated heparin (UFH) is the primary treatment choice. We conducted a systematic review evaluating intraoperative anticoagulation strategies for patients with a history of HIT who required cardiac surgery with cardiopulmonary bypass. Guidance statements were generated through consensus of the writing group. Of 1…

Exploring racial dis(con)cordance and self-affirmation in physical activity messaging to Black women.

OBJECTIVE: Black women are among the least physically active demographic groups in the United States, partly due to sociocultural barriers and medical mistrust. The present research examined whether self-affirmation could help racially discordant physicians enhance Black women's receptivity to a targeted physical activity promotion message. METHOD: In a single-session online experiment, Black women participants (N = 370) completed either a self-affirmation or control writing task before reading a targeted health promotion message about increasing physical activity from a Black or White male p…

Impact of a brief self-compassion intervention on state emotion dysregulation in self-reported generalized anxiety disorder.

BACKGROUND AND OBJECTIVES: The current study examined emotion dysregulation and self-compassion as an intervention in individuals with gener … presenting for treatment of GAD. The demonstrated effects were on state measures following a brief writing intervention; additional research is needed to assess the impact of more extensive self-compassion interventions over a longer time frame. CONCLUSIONS: The results align with theory and previous studies, revealing heightened emotion dysregulation a …

Preliteracy Skills in Young Children Who are Deaf/Hard of Hearing: Secondary Analysis of the Technology-assisted Language Intervention Randomized Trials.

OBJECTIVES: Most children exhibit preliteracy skills by preschool. Children who are deaf/hard of hearing (DHH) with a language gap are at ri … 48 weeks. Repeated-measures models assessed changes in total PRS scores and Early Reading and Early Writing subdomains. Results were presented as least square mean values with 95% confidence intervals. RESULTS: Forty-five children had completed pre-data and post-data. The mean nonverbal IQ was 99.3 (SD 14.3), and receptive and expressive language were 82 …

Sun Exposure and Type 2 Diabetes Mellitus: A Prospective Follow-up Cohort Study from Southern Sweden.

BACKGROUND/AIM: An inverse association exists between type 2 diabetes mellitus (T2DM) and both plasma vitamin D levels and sun exposure, but … egistry of 1990 by random selection. At the inception of the study, 74% of those women responded in writing to an inquiry (n=29,518) and provided detailed information on their sun exposure habits, age, exercise, education, and age at menarche. At the 11-year follow-up, 24,098 responses were received. We analyzed the data using logistic regression analysis …

Exploring Dyslexia Risk Through Psycholinguistic and Orofacial Correlates: Neurodevelopmental Insights Toward a Personalized Medicine Approach.

Background/Objectives: Dyslexia and dysgraphia are common childhood neurodevelopmental disorders characterized by persistent reading and writing difficulties, despite normal intelligence and access to education. While typically described as cognitive-linguistic deficits, emerging research suggests potential links to orofacial dysfunction and emotional regulation issues. This study examines associations between stomatognathic anomalies, emotional dysregulation, and early indicators of dyslexia-dysgraphia risk in preschool children, aiming to strengthen early screening and intervention strategie…

Looking Beyond the Lines: Mental Health Co-Occurrences and Future Treatment Considerations for Dyslexic Populations.

PURPOSE: Dyslexic students can present complex profiles with associated co-occurrences. One co-occurrence of interest involving dyslexic stu … res were divided into either directly addressing mental health morbidities or improving reading and writing skills to indirectly address the student's co-occurrences. Most findings indicated significant improvements involving dyslexia-related difficulties and reducing co-occurrence effects. However, factors such as study designs, small sample sizes, and s …

[Review of the Global Burden of Tuberculosis in 2023: Insights from the WHO Global Tuberculosis Report 2024].

OBJECTIVES: Tuberculosis (TB), caused by the airborne Mycobacterium tuberculosis (Mtb), requires a treatment of minimum 6 months. About a quarter of the world’s population is infected with Mtb. Globally in 2023, an estimated 10.8 million people fell ill with TB. This report accounts for TB incidence and mortality in 2023 in the Republic of Korea (ROK) and Organisation for Economic Co-operation and Development (OECD) member countries, and globally, based on the Global Tuberculosis Report 2024. METHODS: This report refers to a writing extracted the Global Tuberculosis Report 2024 and analyzed u…

U.S. Vietnamese Parents' Perceptions of Different Approaches for Confirming Adolescent HPV Vaccination Records in Research Studies.

BACKGROUND: The United States (U.S.) Vietnamese communities face a high burden of HPV-related cancer rates; they also have low HPV vaccinati … CONTRIBUTION: Community involvement was integral to the design, implementation of this project, and writing of the manuscript. The study team partnered with a community organization that works closely with the U.S. Vietnamese population and Vietnamese healthcare providers. The group met regularly to discuss participant recruitment strategies and study ins …

Approach to childhood tremors: Insights from a pediatric neurologist.

OBJECTIVE: This study aimed to analyze the demographic, clinical, and therapeutic profiles of pediatric patients diagnosed with tremor at a … cant statistical differences were noted in difficulties with drinking water, using a spoon, and handwriting impairments. CONCLUSION: Childhood tremor is a common clinical condition with diverse etiologies, where treatable causes, especially vitamin deficiencies, play a significant role. Functional impairments, such as difficulty in drinking water, using …

Pediatric early-onset neuropsychiatric obsessive compulsive disorders.

At the time of this writing, most pediatricians or child psychiatrists will probably have treated a child with early acute-onset obsessive compulsive disorder (OCD) behaviors due to the pediatric autoimmune neuropsychiatric disorder associated with Group A beta-hemolytic streptococcus, abbreviated PANDAS, described more than two decades ago; or Tourette syndrome, incorporating motor and vocal tics, described more than a century ago. One typically self-limited post-infectious OCD resulting from exposure to other putative microbial disease triggers defines PANS, abbreviating pediatric autoimmune…

Environmental Risk Factors in Isolated Dystonia: A Systematic Scoping Review.

BACKGROUND: Isolated dystonia, a neurological disorder characterized by abnormal postures and repetitive movements, has a complex etiology i … were identified between peripheral trauma and cervical dystonia (odds ratio), and between prolonged writing (>3 hours/day) and writer's cramp. Moderate associations were found between cranial trauma and blepharospasm and betel nut consumption with oromandibular dystonia. Conversely, tobacco use showed a protective effect against blepharospasm. Early-life …

Рефлексология ног в случае утомления, связанного с множественным склерозом: систематический обзор.

Усталость, широко распространенный и серьезный симптом у пациентов с множественным склерозом, негативно сказывается на повседневной жизни пациентов и их качестве жизни. Хотя в последние годы рефлексология ног широко использовалась в борьбе с усталостью, ее воздействие на многих пациентов, страдающих от усталости, связанной со склерозом, остается неясным. ЦЕЛЬ ПРИМЕНИТЕЛЬНОГО ИССЛЕДОВАНИЯ: Цель этого систематического обзора заключалась в изучении воздействия рефлексологии ног на многократную усталость, связанную со склерозом. МЕТОДЫ/ДЕСИГН: Протокол систематического обзора и подготовка статей о

Совпадение в аннотации оригинала
BACKGROUND: Fatigue, a common and serious symptom in multiple sclerosis patients, negatively affects patients' activities of daily living an … clerosis-associated fatigue. METHODS/DESIGN: The protocol of the systematic review and the article writing were based on Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols criteria. In this systematic review, the literature search was conducted in September 2022, in the databases "Scopus, Web of Science, PubMed, and Cochrane Libr …

Adjusting to living with chronic liver disease among patients who continue regular healthcare visits for hepatocellular carcinoma surveillance: A grounded theory study.

AIM: To explore patients' process of living with chronic liver disease while continuing regular healthcare visits for hepatocellular carcinoma surveillance. METHODS: Semistructured interviews and participant observations were conducted in this qualitative constructivist grounded theory study. The participants included 11 patients undergoing regular hepatocellular carcinoma surveillance every 1-6 months for 2-30 years. Data were analyzed using coding, memo-writing, theoretical sampling, and constant comparison. RESULTS: The participants incorporated regular healthcare visits into their living…

Combination of anlotinib and toripalimab for an advanced biliary tract cancer patient with high Eastern Cooperative Oncology Group performance status: a case report.

Up to 80% of biliary tract cancer (BTC) patients relapse within 3 years after surgery and the efficacy of second-line treatment remains dism … us survival benefit from treatment of anlotinib plus toripalimab after lung radiotherapy. Until the writing of the case draft, he had achieved another 11 months of PFS. The present case suggests that anlotinib plus toripalimab might be a potential effective treatment for advanced BTCs patients with high ECOG performance status.

Building a community of practice to address alcohol harms in Canada: Experience from the Canadian Alcohol Policy Evaluation project.

SETTING: Alcohol is a major cause of health and social costs and harms in Canada. While research and awareness of harms caused by alcohol ar … and international jurisdictions. CoP members engage in learning opportunities, contribute to letter-writing campaigns in support of alcohol policy initiatives, and lead a working group focused on alcohol warning labels. Through the CoP, members report gaining and applying new knowledge in their work, while also establishing valuable connections and collab …

Enhancing the Functional Performance of Patients with Late-Stage Age-Related Macular Degeneration Implanted with a Miniature Telescope using Rehabilitation Training.

INTRODUCTION: In this work, our aim is to report the functional outcomes of cataract surgery with smaller-incision new-generation miniature telescope (SING IMT) implantation followed by rehabilitation training in patients with central visual loss due to late-stage age-related macular degeneration (AMD). METHODS: This retrospective study included patients who were monocularly implanted with SING IMT and then followed a rehabilitation program based on 6 biweekly sessions focused on visual abilities, reading, writing, visual motor integration and mobility. A total of 11 participants were include…

Be kind, don't rewind: trait rumination may hinder the effects of self-compassion on health behavioral intentions after a body image threat.

Many individuals encounter situations that may elicit body-related concerns and impact how they think and feel about their weight, daily hab … state and predict poor health behaviors. The present study examined whether a brief self-compassion writing exercise, after recalling a negative body-related event, predicted intent to perform health-promoting behaviors, and whether trait rumination attenuated this relationship. Participants (N = 217) completed a measure of trait rumination, underwent a b …

The Relationship Between Auditory and Cognitive Processing Abilities in Children With Specific Learning Disorders.

PURPOSE: Specific learning disorder (SLD) refers to a pattern of learning difficulties characterized by problems with reading, writing, or mathematics that are not solely due to intellectual disabilities, sensory deficits, or other neurological or medical conditions. It is a neurodevelopmental disorder that affects the processing and organizing of information. Auditory and cognitive processing is affected in most children with SLD, although to a varying degree. However, it is still unclear whether there exists any relationship between auditory and cognitive processing disorders in children wit…