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Advances in materials Исследование related to orbital reconstruction: A review.

Orbital injuries or defects caused by various reasons are quite common, such as violent trauma or tumors. If the damaged orbits are not treated in a timely manner and the normal orbital structure cannot be restored, it may lead to ocular nerve injury, embedding or protrusion of orbital contents, and complications such as enophthalmos, diplopia, and eye movement disorders. Therefore, it is particularly important to repair orbital injuries or defects and reconstruct the normal structure of the orbit. Currently, there are various types of implants applied to reconstruct the orbit, which can be ca

A histopathology image dataset for Johne's disease detection and Исследование.

Johne's disease (paratuberculosis), caused by Mycobacterium avium subspecies paratuberculosis, is a chronic intestinal infection that affect … seful for supervised machine learning applications, computer-aided diagnosis, and digital pathology Исследование. In addition to supporting the development of automated detection systems, the dataset serves as a valuable educational resource for training veterinary pathology students in recognizing histological patterns associated with MAP infection. To the be …

Research progress on microglial pyroptosis and inflammasomes: a comprehensive analysis.

BACKGROUND: Microglial pyroptosis and inflammasome activation play critical roles in neurodegenerative diseases, especially Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS). In recent years, substantial attention has been directed toward elucidating their underlying mechanisms, diagnostic approaches, and prognostic implications. This study aimed to analyze the current Исследование landscape, hotspots, and trends in this field. METHODS: Articles published over the past decade on microglial pyroptosis and inflammasomes were retrieved from the Web of Science Core Colle…

Джанкарло Коми: наследие в неврологии и многочисленных склерозовых исследованиях.

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… He was also recognized as an honorary member of the Brazilian Committee for Treatment and Research in Multiple Sclerosis (BCTRIMS) for his unwavering engagement, support of scientific initiatives, and efforts to integrate Brazilian Исследованиеers into the global scientific community. … Above all, he was a dedicated scientist who never lost his passion for teaching, Исследование, and inspiring new generations of scientists. He always believed in global collaboration, working with Исследованиеers worldwide, including partnerships with Brazil. …

Research progress on ferroptosis in the pathogenesis and treatment of neurodegenerative diseases.

Globally, millions of individuals are impacted by neurodegenerative disorders including Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD). Although a great deal of energy and financial resources have been invested in disease-related Исследование, breakthroughs in therapeutic approaches remain elusive. The breakdown of cells usually happens together with the onset of neurodegenerative diseases. However, the mechanism that triggers neuronal loss is unknown. Lipid peroxidation, which is iron-dependent, causes a specific type of cell…

Research progress of orbital fat in histology and cytology: A review.

Orbital fat is an adipose tissue located behind orbital septum and originates from mesoderm and neural crest in ectoderm. It has been found that the histologic structure of orbital fat is different from subcutaneous and visceral fat. In addition, the regeneration and anti-inflammatory ability of stem cells derived from orbital fat have attracted much attention in recent years. This paper reviews the recent Исследование progress on orbital fat, including its structure, origin, histological characteristics, and related stem cells.

Research on the Thermal Aging Mechanism of Polyvinyl Alcohol Hydrogel.

Polyvinyl alcohol (PVA) hydrogels find applications in various fields, including machinery and tissue engineering, owing to their exceptional mechanical properties. However, the mechanical properties of PVA hydrogels are subject to alteration due to environmental factors such as temperature, affecting their prolonged utilization. To enhance their lifespan, it is crucial to investigate their aging mechanisms. Using physically cross-linked PVA hydrogels, this study involved high-temperature accelerated aging tests at 60 °C for 80 d and their performance was analyzed through macroscopic mechanics

Research progress on mechanism of acupuncture in treating functional constipation.

Acupuncture treatment for functional constipation (FC) is characterized by precise efficacy, rapid onset of action in the early stages, long-term stable effects, and overall regulation. This paper reviews recent literatures on acupuncture treatment for FC, indicating that acupuncture acts from multiple perspectives and pathways, including promoting intestinal motility, regulating intestinal microbiota, modulating the brain-gut axis, alleviating intestinal inflammation, and improving rectal hyposensitivity. Future Исследование could delve into the mechanical sensation conduction mechanisms of acupu…

Research progress on gene mutations and drug resistance in leukemia.

Leukemia is a type of blood cancer characterized by the uncontrolled growth of abnormal cells in the bone marrow, which replace normal blood … specific drug-resistant mutations, providing potential avenues to mitigate leukemia relapse. Future Исследование with these strategies holds promise for advancing leukemia treatment and addressing the challenges of drug-resistant mutations to improve patient outcomes.

[Research and development of intraoral scanning in edentulous soft tissue].

During the complete denture restoration process, accurate impression making is a crucial step for achieving good denture retention. With the increasing popularity of intraoral scanning technology in fixed restoration, the use of intraoral scanning technology in complete denture restoration for edentulous jaw has also been developed. This article systematically reviews the Исследование progress and application of intraoral scanning of edentulous soft tissue, focusing on difficulties in intraoral scanning of edentulous jaws, scanning accuracy, clinical application effects, as well as precautions inv…

[Research progress of metabolomics in children with irritable bowel syndrome].

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by symptoms such as abdominal pain, diarrhea, … omics technology is expected to offer novel insights and methodologies for the biological mechanism Исследование, diagnosis, and treatment of IBS. This article reviews recent advancements in the application of metabolomics to IBS, exploring its potential value in the clinical diagnosis and treatment of children with this condition.

Exploring trends and developments in cholesteatoma Исследование: a bibliometric analysis.

PURPOSE: Examination of the scientific literature on cholesteatoma from past to present using bibliometric methods. METHODS: A total of 235 … bsequently, the trend of increased interest has risen rapidly in later years, with notable peaks in Исследование intensity observed in 1989, 2006, and 2011. The highest academic trend occurred in 2006. In recent years, trending topics have included innovative approaches such as diagnostic and imaging methods particularly alongside technological developments, e …

[Progress in Исследование of incidence of aortic dissection and risk factors].

The incidence rate of aortic dissection (AD) is low, but it is highly fatal in the acute phase. Miss diagnosis and misdiagnosis can occur occasionally, resulting the miss of the best intervention time. Research on the epidemiological characteristics and of AD and related risk factors can identify high-risk groups, make screening and diagnosis as soon as possible and effectively control the changeable risk factors to reduce the incidence of AD and improve the outcome of AD cases. This paper summarizes the progress in Исследование of the epidemiological characteristics of AD and related risk factors…

Science mapping and Исследование trends of strabismus: a Scientometric analysis.

Aim: To draw and analyze a science map and Исследование trends in the field of strabismus with the method of co-word analysis. Method: In this Scientometric study, all scientific outputs in the field of strabismus indexing in the Scopus database between 2005 and 2023 have been analyzed based on various Scientometric indicators. Data analysis was conducted using Excel and VOSviewer softwares. Results: The most significant growth in scientific output occurred in 2021, while the lowest was observed in 2023. The field of strabismus classified in four subject clusters, including Strabismus and Neurolog…

Current Исследование on the interaction between Helicobacter pylori and macrophages.

Helicobacter pylori (H. pylori) is a gram-negative bacteria with a worldwide infection rate of 50%, known to induce gastritis, ulcers and gastric cancer. The interplay between H. pylori and immune cells within the gastric mucosa is pivotal in the pathogenesis of H. pylori-related disease. Following H. pylori infection, there is an observed increase in gastric mucosal macrophages, which are associated with the progression of gastritis. H. pylori elicits macrophage polarization, releases cytokines, reactive oxygen species (ROS) and nitric oxide (NO) to promote inflammatory response and eliminate

Research on magnetic resonance imaging in diagnosis of Alzheimer's disease.

As a common disease in the elderly, the diagnosis of Alzheimer's disease (AD) is of great significance to the treatment and prognosis of the patients. Studies have found that magnetic resonance imaging plays an important role in the early diagnosis of Alzheimer's disease. This article tries to review the application of magnetic resonance imaging in the diagnosis and differential diagnosis of Alzheimer's disease.

Challenges in Psoriasis Research: A Systematic Review of Preclinical Models.

INTRODUCTION: Psoriasis is a chronic inflammatory skin disease with variable clinical presentation, multifactorial etiology and an immunogen … n of effective drugs requires well-characterized and highly available preclinical models that allow Исследованиеers to quickly and reproducibly determine their safety and efficacy. METHODS: A systematic search on PubMed and Scopus databases was performed and assessed to find appropriate articles about psoriasis models applying the key words previously defined …